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The map label for this gene is trxB [H]

Identifier: 237813407

GI number: 237813407

Start: 3078013

End: 3078975

Strand: Direct

Name: trxB [H]

Synonym: GBP346_A3182

Alternate gene names: 237813407

Gene position: 3078013-3078975 (Clockwise)

Preceding gene: 237813403

Following gene: 237813408

Centisome position: 75.1

GC content: 66.87

Gene sequence:

>963_bases
ATGTCCACGCCCAAACACGCGAAAGTCCTGATTCTCGGTTCCGGCCCCGCCGGCTACACGGCGGCCGTCTACGCGGCCCG
CGCGAACCTGTCGCCCCTCCTGATCACGGGCATCGCGCAAGGCGGCCAGCTGATGACGACGACCGACGTCGAGAATTGGC
CGGCCGACGCGGACGGCGTGCAGGGCCCCGAGCTGATGCAGCGCTTTCTCGCGCACGCGCAGCGCTTCAACACCGAGATC
GTGTTCGACCACATCCACACGGCCAAGCTGCACGAGAAGCCGATCCGCCTGATCGGCGACTCGGGCGAATACACGTGCGA
CTCGCTGATCATCGCGACGGGCGCGTCCGCGCAATACCTCGGCCTGCAGTCGGAAGAGGCGTTCATGGGCCGCGGCGTGT
CGGCGTGCGCGACCTGCGACGGCTTCTTCTATCGCGGCCAGAACGTCGCGGTCGTCGGCGGCGGCAACACGGCCGTCGAG
GAAGCGCTCTATCTGACGGGCATCGCGAAGAAGGTCACGGTGATCCACCGCCGCGACAAGTTCCGCGCGGAGCCGATCCT
CGTCGATCGCCTGCTCGAGAAGGAAAAGGAAGGCGCGGTCGAGATCAAGTGGGACCATGTGCTCGACGAGGTGACGGGCG
ACGATTCGGGCGTCTCGGGCGTGCGCATCAAGCACGTGACGACGGGCGCGACCGAGGACGTCGCGGTGCAGGGCCTGTTC
ATCGCGATCGGCCACAAGCCGAACACCGACATCTTCAAGGGCCAGCTCGAGATGAAGGACGGCTACATCATCACGAACAG
CGGCCTGTCGGGCAACGCGACGGGCACGAGCGTGCCAGGCGTGTTCGCGGCGGGCGACGTGCAGGACCACATCTACCGCC
AGGCGATCACGAGCGCGGGCACGGGCTGCATGGCGGCGCTCGACGCGCAGCGCTATCTCGAAAGCCTGCACGACCACAAG
TAA

Upstream 100 bases:

>100_bases
ATAATGCGGGCTTTGCACCCATCTGCGACGGTATCCCGCTCGCAACGGGCCGCCCGGCAGCAACGTCCGCCCGGCCGGCC
GCTTTTTACGGATCCTGCTC

Downstream 100 bases:

>100_bases
AGCGGCGCGGCGGCACGGCGCTACAATGGCGACGCCGCGCGCCGCCTGACGGGTTCGACACACCGCAGCCGCTGCGCGCA
TCGCGCAGCGGCTTTTTCAC

Product: thioredoxin-disulfide reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MSTPKHAKVLILGSGPAGYTAAVYAARANLSPLLITGIAQGGQLMTTTDVENWPADADGVQGPELMQRFLAHAQRFNTEI
VFDHIHTAKLHEKPIRLIGDSGEYTCDSLIIATGASAQYLGLQSEEAFMGRGVSACATCDGFFYRGQNVAVVGGGNTAVE
EALYLTGIAKKVTVIHRRDKFRAEPILVDRLLEKEKEGAVEIKWDHVLDEVTGDDSGVSGVRIKHVTTGATEDVAVQGLF
IAIGHKPNTDIFKGQLEMKDGYIITNSGLSGNATGTSVPGVFAAGDVQDHIYRQAITSAGTGCMAALDAQRYLESLHDHK

Sequences:

>Translated_320_residues
MSTPKHAKVLILGSGPAGYTAAVYAARANLSPLLITGIAQGGQLMTTTDVENWPADADGVQGPELMQRFLAHAQRFNTEI
VFDHIHTAKLHEKPIRLIGDSGEYTCDSLIIATGASAQYLGLQSEEAFMGRGVSACATCDGFFYRGQNVAVVGGGNTAVE
EALYLTGIAKKVTVIHRRDKFRAEPILVDRLLEKEKEGAVEIKWDHVLDEVTGDDSGVSGVRIKHVTTGATEDVAVQGLF
IAIGHKPNTDIFKGQLEMKDGYIITNSGLSGNATGTSVPGVFAAGDVQDHIYRQAITSAGTGCMAALDAQRYLESLHDHK
>Mature_319_residues
STPKHAKVLILGSGPAGYTAAVYAARANLSPLLITGIAQGGQLMTTTDVENWPADADGVQGPELMQRFLAHAQRFNTEIV
FDHIHTAKLHEKPIRLIGDSGEYTCDSLIIATGASAQYLGLQSEEAFMGRGVSACATCDGFFYRGQNVAVVGGGNTAVEE
ALYLTGIAKKVTVIHRRDKFRAEPILVDRLLEKEKEGAVEIKWDHVLDEVTGDDSGVSGVRIKHVTTGATEDVAVQGLFI
AIGHKPNTDIFKGQLEMKDGYIITNSGLSGNATGTSVPGVFAAGDVQDHIYRQAITSAGTGCMAALDAQRYLESLHDHK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=321, Percent_Identity=67.2897196261682, Blast_Score=449, Evalue=1e-127,
Organism=Escherichia coli, GI87081763, Length=312, Percent_Identity=33.6538461538462, Blast_Score=135, Evalue=5e-33,
Organism=Saccharomyces cerevisiae, GI6320560, Length=324, Percent_Identity=46.6049382716049, Blast_Score=271, Evalue=8e-74,
Organism=Saccharomyces cerevisiae, GI6321898, Length=322, Percent_Identity=46.2732919254658, Blast_Score=270, Evalue=2e-73,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34138; Mature: 34007

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPKHAKVLILGSGPAGYTAAVYAARANLSPLLITGIAQGGQLMTTTDVENWPADADGV
CCCCCCEEEEEEECCCCCCEEEEEEECCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCC
QGPELMQRFLAHAQRFNTEIVFDHIHTAKLHEKPIRLIGDSGEYTCDSLIIATGASAQYL
CCHHHHHHHHHHHHHCCCEEEEECHHHHHHCCCCEEEECCCCCCEECEEEEEECCCCEEE
GLQSEEAFMGRGVSACATCDGFFYRGQNVAVVGGGNTAVEEALYLTGIAKKVTVIHRRDK
CCCCCHHHHCCCCHHHEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHEEEEEECCC
FRAEPILVDRLLEKEKEGAVEIKWDHVLDEVTGDDSGVSGVRIKHVTTGATEDVAVQGLF
CCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCEEEEEEECCCCCCEEEEEEE
IAIGHKPNTDIFKGQLEMKDGYIITNSGLSGNATGTSVPGVFAAGDVQDHIYRQAITSAG
EEECCCCCCCEEEEEEEECCCEEEECCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHCC
TGCMAALDAQRYLESLHDHK
CCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STPKHAKVLILGSGPAGYTAAVYAARANLSPLLITGIAQGGQLMTTTDVENWPADADGV
CCCCCEEEEEEECCCCCCEEEEEEECCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCC
QGPELMQRFLAHAQRFNTEIVFDHIHTAKLHEKPIRLIGDSGEYTCDSLIIATGASAQYL
CCHHHHHHHHHHHHHCCCEEEEECHHHHHHCCCCEEEECCCCCCEECEEEEEECCCCEEE
GLQSEEAFMGRGVSACATCDGFFYRGQNVAVVGGGNTAVEEALYLTGIAKKVTVIHRRDK
CCCCCHHHHCCCCHHHEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHEEEEEECCC
FRAEPILVDRLLEKEKEGAVEIKWDHVLDEVTGDDSGVSGVRIKHVTTGATEDVAVQGLF
CCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCEEEEEEECCCCCCEEEEEEE
IAIGHKPNTDIFKGQLEMKDGYIITNSGLSGNATGTSVPGVFAAGDVQDHIYRQAITSAG
EEECCCCCCCEEEEEEEECCCEEEECCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHCC
TGCMAALDAQRYLESLHDHK
CCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]