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The map label for this gene is rdgB [C]

Identifier: 237813383

GI number: 237813383

Start: 3057112

End: 3057744

Strand: Direct

Name: rdgB [C]

Synonym: GBP346_A3156

Alternate gene names: 237813383

Gene position: 3057112-3057744 (Clockwise)

Preceding gene: 237813382

Following gene: 237813384

Centisome position: 74.59

GC content: 71.88

Gene sequence:

>633_bases
ATGACGATGTCGCACGCATCGCCCGACGCCGCGCGCTCGCGCATCGTCCTCGCCTCGAACAATCCCGGCAAGCTGCGCGA
GTTCGCCGCGCTCTTCTCGACGGCGGGCATCGACATCGTGCCGCAAGGCGAGCTCGGCGTATCGGAAGCCGACGAACCGC
ACGCGACCTTCGTCGAGAACGCGCTCGCGAAGGCGCGCCATGCGTCGCGCGCGACGGGCCTGCCCGCCGTCGCCGACGAT
TCCGGCCTGTGCGTGCCCGCGCTGCTCGGCGCGCCGGGCGTCTACTCGGCGCGCTACGCGCAGCGCGCCGGCCGCGAGAA
GAGCGATGCGGCGAACAACGCGTATCTCGTCGAGCAGTTGCGCGAGGTCGCGGATCGGCGCGCGTATTACTACTGCGTGC
TCGCGCTCGTGCGGCACGCGGACGATCCGGAGCCGCTCATCGCCGAAGGGCGCTGGGCGGGCGAGATCCTCGACGCACCA
CGCGGCGCGCACGGCTTCGGCTACGATCCGCACTTCTTCGTGCCGGCGCTCGGCGCGACGGCGGCCGAGCTCGATCCGGC
CGCGAAAAACGCGGCGAGCCACCGCGCGCTCGCGCTGAAGGCGCTCGTCGCGCGGCTCGGAGAAATTCGATGA

Upstream 100 bases:

>100_bases
AAGGCGCGCCGTTCTCGCGCACCGAGATGAACGCGCTTCTCGATCTCGCGCAGGCCGGCATCGGCGAGCTCGTGCGGCTG
CAGCGCGCGGCGCTGGAGGC

Downstream 100 bases:

>100_bases
GCGACGCGGCAACCAACGGCGCGCGCGTCGTCGCGACATTCGCCGCGCCCGGCCGGATCCGGCTCGCGTCGCTGCCGCCG
CTCGCGCTGTACGTGCACTT

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MTMSHASPDAARSRIVLASNNPGKLREFAALFSTAGIDIVPQGELGVSEADEPHATFVENALAKARHASRATGLPAVADD
SGLCVPALLGAPGVYSARYAQRAGREKSDAANNAYLVEQLREVADRRAYYYCVLALVRHADDPEPLIAEGRWAGEILDAP
RGAHGFGYDPHFFVPALGATAAELDPAAKNAASHRALALKALVARLGEIR

Sequences:

>Translated_210_residues
MTMSHASPDAARSRIVLASNNPGKLREFAALFSTAGIDIVPQGELGVSEADEPHATFVENALAKARHASRATGLPAVADD
SGLCVPALLGAPGVYSARYAQRAGREKSDAANNAYLVEQLREVADRRAYYYCVLALVRHADDPEPLIAEGRWAGEILDAP
RGAHGFGYDPHFFVPALGATAAELDPAAKNAASHRALALKALVARLGEIR
>Mature_209_residues
TMSHASPDAARSRIVLASNNPGKLREFAALFSTAGIDIVPQGELGVSEADEPHATFVENALAKARHASRATGLPAVADDS
GLCVPALLGAPGVYSARYAQRAGREKSDAANNAYLVEQLREVADRRAYYYCVLALVRHADDPEPLIAEGRWAGEILDAPR
GAHGFGYDPHFFVPALGATAAELDPAAKNAASHRALALKALVARLGEIR

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=199, Percent_Identity=30.6532663316583, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI31657144, Length=152, Percent_Identity=34.2105263157895, Blast_Score=71, Evalue=9e-13,
Organism=Escherichia coli, GI1789324, Length=196, Percent_Identity=52.5510204081633, Blast_Score=201, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17556833, Length=192, Percent_Identity=30.2083333333333, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 22193; Mature: 22062

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMSHASPDAARSRIVLASNNPGKLREFAALFSTAGIDIVPQGELGVSEADEPHATFVEN
CCCCCCCCHHHHCEEEEECCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHH
ALAKARHASRATGLPAVADDSGLCVPALLGAPGVYSARYAQRAGREKSDAANNAYLVEQL
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHH
REVADRRAYYYCVLALVRHADDPEPLIAEGRWAGEILDAPRGAHGFGYDPHFFVPALGAT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHCCCH
AAELDPAAKNAASHRALALKALVARLGEIR
HHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TMSHASPDAARSRIVLASNNPGKLREFAALFSTAGIDIVPQGELGVSEADEPHATFVEN
CCCCCCCHHHHCEEEEECCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHH
ALAKARHASRATGLPAVADDSGLCVPALLGAPGVYSARYAQRAGREKSDAANNAYLVEQL
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHH
REVADRRAYYYCVLALVRHADDPEPLIAEGRWAGEILDAPRGAHGFGYDPHFFVPALGAT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHCCCH
AAELDPAAKNAASHRALALKALVARLGEIR
HHHCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA