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The map label for this gene is nagZ [H]

Identifier: 237813190

GI number: 237813190

Start: 2878954

End: 2879982

Strand: Reverse

Name: nagZ [H]

Synonym: GBP346_A2955

Alternate gene names: 237813190

Gene position: 2879982-2878954 (Counterclockwise)

Preceding gene: 237813191

Following gene: 237813188

Centisome position: 70.27

GC content: 70.55

Gene sequence:

>1029_bases
ATGAAACTGCCCCCCGGTCCGGTGATGCTCGACGTCGCCGGCACGACGCTCACGCGCGACGACGCGCGCCGCCTCGCGCA
TCCGCACACGGGCGGCGTGATCCTGTTCGCGCGCCACTTCGAGAGCCGCGCGCAACTCGTCGCGCTGACCGAGGCGATCC
GGGCGATCCGCGACGGCATCCTGATCGCGGTCGATCACGAGGGCGGCCGCGTGCAGCGCTTTCGCACCGACGGCTTCACC
GTGCTGCCGGCGATGCGCCGGCTCGGCGAGCTGTGGGACAAGGACGTGCTGCACGCGACGAAGGCGGCGACCGCGCTCGG
CTATGTGCTCGCTTCCGAGCTGCGCGCGTGCGGCATCGACATGAGCTTCACGCCCGTGCTCGATCTCGATTACGGCCGCT
CGAAGGTGATCGGCGATCGCGCGTTCCATCGCGATCCGCGCGTCGTCGCGTTGCTCGCGAAGAGCGTCAACCACGGGCTC
GCGCTCGCCGGGATGGCGAACTGCGGCAAGCATTTTCCCGGCCACGGCTTCGCGCAGGCCGATTCGCACGTCGCGCTGCC
GACCGACGATCGTCCGCTCGACGAGATCCTCGCGAACGACGCGGCGCCGTACGACTGGCTCGGGCTGTCGTTGTCGGCCG
TCATTCCGGCGCACGTGATCTACACGCAGGTCGATTCGAAGCCGGCCGGCTTCTCGCGCGTGTGGTTGCAGGACGTGCTG
CGCGGCCGGCTGCGCTTTGCGGGCGCCGTGTTCAGCGACGATCTGTCGATGGAGGCCGCGCGCGAGGGCGGCACGCTCGC
GCAGTCGGCGCAGGCCGCGCTCGAGGCGGGCTGCGACATGGTGCTCGTGTGCAACCAGCCGGATGCGGCGGAGCGGGTGC
TCGACGAGCTGCGCACGACGGCGTCGCGCGAATCGTCGCGGCGGATCAAGCAGATGCGGCCGCGCGGCAAGGCGCTCGAG
TGGCGCAAGCTGATGCGCGAGCCGCGCTATCTGAATGCGCAGGGCCTGTTGCGCAGCACGTTCGCCTGA

Upstream 100 bases:

>100_bases
TTACGCGGTCACGTTCGTCGTCGCCGAGGCGCCGGACGACGTCGCCGCCGCGCGCTCGGGCGCCGCTTCCTGATCCATTT
TCCGCAAGGACGCTGATTCG

Downstream 100 bases:

>100_bases
CGCGAAGCGAAAACGGCAGCCGAAGACGGGAGAGGGCGCAGCGAAGGCGCGATGAAGGCGAAACGCAGCCGACGCACGGG
GCGGCGCGGCGGCTCGTTCG

Product: beta-hexosaminidase

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MKLPPGPVMLDVAGTTLTRDDARRLAHPHTGGVILFARHFESRAQLVALTEAIRAIRDGILIAVDHEGGRVQRFRTDGFT
VLPAMRRLGELWDKDVLHATKAATALGYVLASELRACGIDMSFTPVLDLDYGRSKVIGDRAFHRDPRVVALLAKSVNHGL
ALAGMANCGKHFPGHGFAQADSHVALPTDDRPLDEILANDAAPYDWLGLSLSAVIPAHVIYTQVDSKPAGFSRVWLQDVL
RGRLRFAGAVFSDDLSMEAAREGGTLAQSAQAALEAGCDMVLVCNQPDAAERVLDELRTTASRESSRRIKQMRPRGKALE
WRKLMREPRYLNAQGLLRSTFA

Sequences:

>Translated_342_residues
MKLPPGPVMLDVAGTTLTRDDARRLAHPHTGGVILFARHFESRAQLVALTEAIRAIRDGILIAVDHEGGRVQRFRTDGFT
VLPAMRRLGELWDKDVLHATKAATALGYVLASELRACGIDMSFTPVLDLDYGRSKVIGDRAFHRDPRVVALLAKSVNHGL
ALAGMANCGKHFPGHGFAQADSHVALPTDDRPLDEILANDAAPYDWLGLSLSAVIPAHVIYTQVDSKPAGFSRVWLQDVL
RGRLRFAGAVFSDDLSMEAAREGGTLAQSAQAALEAGCDMVLVCNQPDAAERVLDELRTTASRESSRRIKQMRPRGKALE
WRKLMREPRYLNAQGLLRSTFA
>Mature_342_residues
MKLPPGPVMLDVAGTTLTRDDARRLAHPHTGGVILFARHFESRAQLVALTEAIRAIRDGILIAVDHEGGRVQRFRTDGFT
VLPAMRRLGELWDKDVLHATKAATALGYVLASELRACGIDMSFTPVLDLDYGRSKVIGDRAFHRDPRVVALLAKSVNHGL
ALAGMANCGKHFPGHGFAQADSHVALPTDDRPLDEILANDAAPYDWLGLSLSAVIPAHVIYTQVDSKPAGFSRVWLQDVL
RGRLRFAGAVFSDDLSMEAAREGGTLAQSAQAALEAGCDMVLVCNQPDAAERVLDELRTTASRESSRRIKQMRPRGKALE
WRKLMREPRYLNAQGLLRSTFA

Specific function: Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides [H]

COG id: COG1472

COG function: function code G; Beta-glucosidase-related glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787350, Length=305, Percent_Identity=47.2131147540984, Blast_Score=250, Evalue=1e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022956
- InterPro:   IPR019800
- InterPro:   IPR001764
- InterPro:   IPR017853 [H]

Pfam domain/function: PF00933 Glyco_hydro_3 [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 37416; Mature: 37416

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLPPGPVMLDVAGTTLTRDDARRLAHPHTGGVILFARHFESRAQLVALTEAIRAIRDGI
CCCCCCCEEEEECCCEECHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCE
LIAVDHEGGRVQRFRTDGFTVLPAMRRLGELWDKDVLHATKAATALGYVLASELRACGID
EEEEECCCCCEEEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
MSFTPVLDLDYGRSKVIGDRAFHRDPRVVALLAKSVNHGLALAGMANCGKHFPGHGFAQA
CCCCEEEECCCCCCHHHCCHHHCCCCHHHHHHHHHHCCCEEEEEHHHCCCCCCCCCCCCC
DSHVALPTDDRPLDEILANDAAPYDWLGLSLSAVIPAHVIYTQVDSKPAGFSRVWLQDVL
CCEEECCCCCCCHHHHHCCCCCCCHHHCCHHHHHHHHHHEEEECCCCCCCHHHHHHHHHH
RGRLRFAGAVFSDDLSMEAAREGGTLAQSAQAALEAGCDMVLVCNQPDAAERVLDELRTT
HHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHH
ASRESSRRIKQMRPRGKALEWRKLMREPRYLNAQGLLRSTFA
HHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MKLPPGPVMLDVAGTTLTRDDARRLAHPHTGGVILFARHFESRAQLVALTEAIRAIRDGI
CCCCCCCEEEEECCCEECHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCE
LIAVDHEGGRVQRFRTDGFTVLPAMRRLGELWDKDVLHATKAATALGYVLASELRACGID
EEEEECCCCCEEEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
MSFTPVLDLDYGRSKVIGDRAFHRDPRVVALLAKSVNHGLALAGMANCGKHFPGHGFAQA
CCCCEEEECCCCCCHHHCCHHHCCCCHHHHHHHHHHCCCEEEEEHHHCCCCCCCCCCCCC
DSHVALPTDDRPLDEILANDAAPYDWLGLSLSAVIPAHVIYTQVDSKPAGFSRVWLQDVL
CCEEECCCCCCCHHHHHCCCCCCCHHHCCHHHHHHHHHHEEEECCCCCCCHHHHHHHHHH
RGRLRFAGAVFSDDLSMEAAREGGTLAQSAQAALEAGCDMVLVCNQPDAAERVLDELRTT
HHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHH
ASRESSRRIKQMRPRGKALEWRKLMREPRYLNAQGLLRSTFA
HHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]