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The map label for this gene is pdxY [H]

Identifier: 237813160

GI number: 237813160

Start: 2850013

End: 2850876

Strand: Direct

Name: pdxY [H]

Synonym: GBP346_A2922

Alternate gene names: 237813160

Gene position: 2850013-2850876 (Clockwise)

Preceding gene: 237813159

Following gene: 237813162

Centisome position: 69.54

GC content: 68.98

Gene sequence:

>864_bases
ATGAAAAACGTCCTCAGCATCCAGTCGCACGTCATCTACGGACATGCGGGCAACAGCGCCGCAGTGTTTCCGATGCAACG
GCTCGGCGTCAATGTCTGGCCGCTCAACACCGTGCAGTTGTCGAACCACATGCAGTACGGCCATTGGGCGGGCAGCGCGA
TCGACGCGGCGAAGATGGAGCAGCTCGTCGACGGCATCGCGGCGATCGGCGCGCTCAAGCGCTGCGACGCGGTGCTCTCG
GGCTTCCTCGGCTCGCCCGCGCAGGCGCGCGCGGCAGTCGAGATCGTGCGCACCGTGAAGGCGACGAATCCGAACGCGTG
GTACTTCTGCGATCCGGCGATGGGCCAGACGGGCGGCATCCGGCCGGAGCCCGGCGTCGAGGAGTTCATCGTCGCCGAGC
TGCCCGAGCTCGCGGACGGCATGGCGCCCAATCACAGCGAGCTGCAAAAGCTCGCCGGGCAGCGCATCGAGACGGTCGCC
GAGGCCGTCGCCGCGTGCCGCTCGATCATCCGCCGCGGCCCGCAGGTGATCCTCGTCAAGCATTTGCACGATCGCAACAG
CCCCGCCGACCGTTTCAACATGCTCGTCGTCACCGAGACCGAAGCATGGATCGGCCAGCGGCCGCTGTACGCGTTCCCGC
GGCATCCGGTCGGCGTCGGCGACCTGACGAGCGCGATCTTCGTCGCACGGCGGCTGCGCGGCGACAGCGTGCGCGCCGCG
TTCGAGCACACGCTCGCCGCCGTGCACGCGGTTGTCAAGGCGACCTACGACGCACGGCGCTACGAGCTCGAGCTCGTCGC
CGCGCAGGACGAGATCGCGCGGCCGAGCGAGTGGTTCGGCGCGTGGGTCACGGGCGCGGATTGA

Upstream 100 bases:

>100_bases
CCCTCCGATACCGTATTACCGGATGCTTCCGTGAATGCGGGAAAGTCATGTATCGTTCGACGTAATCCGGCGAGCTCGCC
GCGCGCCGGCACACTCGATC

Downstream 100 bases:

>100_bases
TGCGCGGCGCGCGCCGGTTCGCGTGTTGATCCGCACGCTCGATCGCGCGCCCCCGTTCGAGCCGCCGCGGCGGCGCCACG
CGGTGTCGCGGCACCCGTCG

Product: pyridoxal kinase

Products: NA

Alternate protein names: PM kinase [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MKNVLSIQSHVIYGHAGNSAAVFPMQRLGVNVWPLNTVQLSNHMQYGHWAGSAIDAAKMEQLVDGIAAIGALKRCDAVLS
GFLGSPAQARAAVEIVRTVKATNPNAWYFCDPAMGQTGGIRPEPGVEEFIVAELPELADGMAPNHSELQKLAGQRIETVA
EAVAACRSIIRRGPQVILVKHLHDRNSPADRFNMLVVTETEAWIGQRPLYAFPRHPVGVGDLTSAIFVARRLRGDSVRAA
FEHTLAAVHAVVKATYDARRYELELVAAQDEIARPSEWFGAWVTGAD

Sequences:

>Translated_287_residues
MKNVLSIQSHVIYGHAGNSAAVFPMQRLGVNVWPLNTVQLSNHMQYGHWAGSAIDAAKMEQLVDGIAAIGALKRCDAVLS
GFLGSPAQARAAVEIVRTVKATNPNAWYFCDPAMGQTGGIRPEPGVEEFIVAELPELADGMAPNHSELQKLAGQRIETVA
EAVAACRSIIRRGPQVILVKHLHDRNSPADRFNMLVVTETEAWIGQRPLYAFPRHPVGVGDLTSAIFVARRLRGDSVRAA
FEHTLAAVHAVVKATYDARRYELELVAAQDEIARPSEWFGAWVTGAD
>Mature_287_residues
MKNVLSIQSHVIYGHAGNSAAVFPMQRLGVNVWPLNTVQLSNHMQYGHWAGSAIDAAKMEQLVDGIAAIGALKRCDAVLS
GFLGSPAQARAAVEIVRTVKATNPNAWYFCDPAMGQTGGIRPEPGVEEFIVAELPELADGMAPNHSELQKLAGQRIETVA
EAVAACRSIIRRGPQVILVKHLHDRNSPADRFNMLVVTETEAWIGQRPLYAFPRHPVGVGDLTSAIFVARRLRGDSVRAA
FEHTLAAVHAVVKATYDARRYELELVAAQDEIARPSEWFGAWVTGAD

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=304, Percent_Identity=29.6052631578947, Blast_Score=122, Evalue=6e-28,
Organism=Escherichia coli, GI1787924, Length=283, Percent_Identity=52.6501766784452, Blast_Score=288, Evalue=2e-79,
Organism=Escherichia coli, GI1788758, Length=264, Percent_Identity=26.1363636363636, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17507759, Length=263, Percent_Identity=30.0380228136882, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17507757, Length=273, Percent_Identity=28.9377289377289, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324354, Length=275, Percent_Identity=32, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6320806, Length=275, Percent_Identity=29.8181818181818, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI45553007, Length=292, Percent_Identity=29.1095890410959, Blast_Score=128, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 31176; Mature: 31176

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNVLSIQSHVIYGHAGNSAAVFPMQRLGVNVWPLNTVQLSNHMQYGHWAGSAIDAAKME
CCCHHEEHHEEEEEECCCCEEECCHHHHCCEECCCCEEECCCCCCCCCCCCCHHHHHHHH
QLVDGIAAIGALKRCDAVLSGFLGSPAQARAAVEIVRTVKATNPNAWYFCDPAMGQTGGI
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCC
RPEPGVEEFIVAELPELADGMAPNHSELQKLAGQRIETVAEAVAACRSIIRRGPQVILVK
CCCCCHHHHHHHHCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
HLHDRNSPADRFNMLVVTETEAWIGQRPLYAFPRHPVGVGDLTSAIFVARRLRGDSVRAA
ECCCCCCCHHHEEEEEEEECHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHH
FEHTLAAVHAVVKATYDARRYELELVAAQDEIARPSEWFGAWVTGAD
HHHHHHHHHHHHHHHHCCHHEEEEEEECCHHHCCCHHHHCEEECCCC
>Mature Secondary Structure
MKNVLSIQSHVIYGHAGNSAAVFPMQRLGVNVWPLNTVQLSNHMQYGHWAGSAIDAAKME
CCCHHEEHHEEEEEECCCCEEECCHHHHCCEECCCCEEECCCCCCCCCCCCCHHHHHHHH
QLVDGIAAIGALKRCDAVLSGFLGSPAQARAAVEIVRTVKATNPNAWYFCDPAMGQTGGI
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCC
RPEPGVEEFIVAELPELADGMAPNHSELQKLAGQRIETVAEAVAACRSIIRRGPQVILVK
CCCCCHHHHHHHHCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
HLHDRNSPADRFNMLVVTETEAWIGQRPLYAFPRHPVGVGDLTSAIFVARRLRGDSVRAA
ECCCCCCCHHHEEEEEEEECHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHH
FEHTLAAVHAVVKATYDARRYELELVAAQDEIARPSEWFGAWVTGAD
HHHHHHHHHHHHHHHHCCHHEEEEEEECCHHHCCCHHHHCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA