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The map label for this gene is sufC [H]

Identifier: 237813121

GI number: 237813121

Start: 2815108

End: 2815878

Strand: Direct

Name: sufC [H]

Synonym: GBP346_A2883

Alternate gene names: 237813121

Gene position: 2815108-2815878 (Clockwise)

Preceding gene: 237813120

Following gene: 237813122

Centisome position: 68.69

GC content: 69.26

Gene sequence:

>771_bases
ATGAATCGATCCGAACCCCTGCTGCAGGTATTCGACCTGAGCGTCGAAGTCGCGAAGCGCCGCGTGCTGCAGTCGGTATC
GCTCGCCGTGCCGGCGGGCGCGCTCGTCGTGCTGATGGGCGCGAACGGCAGCGGCAAGAGCACGCTCGGCATGACGCTCG
CGGGCCATCCCGCGTATCGCGCGACGCACGGCCACGTGCGCTTCGGCGGGCAGGACCTGCTCGCGATGAGCGTGCAGGAG
CGCGCGCGCGCCGGCCTGTTCCTGTCGTTCCAGGCGCCGCCCGATATCCCCGGCGTGAAGAACAATCTCTTCATTCGCAC
CGCGCTGAACGCCGTGCGCGAGGCGCGCGGCGACACCGCGCTCGATGCGCTCGACTTTCTCGGCGACGCGCGCGCGGCCG
CCGCGCAAGTCGGCCTATCCGATGCGATGCTCAACCGTTCGATGAACGAAGGATTCTCGGGCGGCGAGCGCAAGCGCAAC
GAGCTGCTGCAGCTCGCGCTGCTGTGCCCGCGGCTCGCGATGCTCGACGAGATCGACTCGGGAATGGACGTCGACGGCGT
GCGCGCGGCGGTCGCCCTGATCGGCCGGCTGCGCGAGCAAGGCACCGCGTTCGTGATCGTCTCGCATTATCTGCAGATGA
TCGAAGCGCTCGCGCCCGATACGGTGCTATTGCTCGATCGCGGGCGCATCGCCGAATCCGGCGATCTCGCACTCGCCCGC
GACATCGCGGCCAAGGGCTTCGCGCGCTCGGACGCACTCGCGCAGGCCTGA

Upstream 100 bases:

>100_bases
CGCTGCCGATGGAGTTCGCGCTCGAGGCGAAGGCATTGCTCGCGGTGTCGCTCGAGGGCGCCGTCGGCTGACCCCACACA
TGACAAACGAAGGAATCGCC

Downstream 100 bases:

>100_bases
AGCGATGACGACGACCGCCACCGACCGGGCCGCCGCGCGAGCCCAACTCGCGCAACACGGCTGGATCTCGCGCCACCACG
AATCGTTCCGCCATCTGCCG

Product: FeS assembly ATPase SufC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MNRSEPLLQVFDLSVEVAKRRVLQSVSLAVPAGALVVLMGANGSGKSTLGMTLAGHPAYRATHGHVRFGGQDLLAMSVQE
RARAGLFLSFQAPPDIPGVKNNLFIRTALNAVREARGDTALDALDFLGDARAAAAQVGLSDAMLNRSMNEGFSGGERKRN
ELLQLALLCPRLAMLDEIDSGMDVDGVRAAVALIGRLREQGTAFVIVSHYLQMIEALAPDTVLLLDRGRIAESGDLALAR
DIAAKGFARSDALAQA

Sequences:

>Translated_256_residues
MNRSEPLLQVFDLSVEVAKRRVLQSVSLAVPAGALVVLMGANGSGKSTLGMTLAGHPAYRATHGHVRFGGQDLLAMSVQE
RARAGLFLSFQAPPDIPGVKNNLFIRTALNAVREARGDTALDALDFLGDARAAAAQVGLSDAMLNRSMNEGFSGGERKRN
ELLQLALLCPRLAMLDEIDSGMDVDGVRAAVALIGRLREQGTAFVIVSHYLQMIEALAPDTVLLLDRGRIAESGDLALAR
DIAAKGFARSDALAQA
>Mature_256_residues
MNRSEPLLQVFDLSVEVAKRRVLQSVSLAVPAGALVVLMGANGSGKSTLGMTLAGHPAYRATHGHVRFGGQDLLAMSVQE
RARAGLFLSFQAPPDIPGVKNNLFIRTALNAVREARGDTALDALDFLGDARAAAAQVGLSDAMLNRSMNEGFSGGERKRN
ELLQLALLCPRLAMLDEIDSGMDVDGVRAAVALIGRLREQGTAFVIVSHYLQMIEALAPDTVLLLDRGRIAESGDLALAR
DIAAKGFARSDALAQA

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787972, Length=242, Percent_Identity=44.6280991735537, Blast_Score=221, Evalue=3e-59,
Organism=Escherichia coli, GI1789962, Length=255, Percent_Identity=30.5882352941176, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787029, Length=233, Percent_Identity=27.0386266094421, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789891, Length=218, Percent_Identity=30.2752293577982, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081709, Length=225, Percent_Identity=28.8888888888889, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87081834, Length=204, Percent_Identity=31.3725490196078, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786654, Length=217, Percent_Identity=29.0322580645161, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786345, Length=218, Percent_Identity=29.8165137614679, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1789593, Length=218, Percent_Identity=28.4403669724771, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788506, Length=233, Percent_Identity=27.0386266094421, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI212646699, Length=233, Percent_Identity=27.0386266094421, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27129; Mature: 27129

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRSEPLLQVFDLSVEVAKRRVLQSVSLAVPAGALVVLMGANGSGKSTLGMTLAGHPAYR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEEECCCCCC
ATHGHVRFGGQDLLAMSVQERARAGLFLSFQAPPDIPGVKNNLFIRTALNAVREARGDTA
CCCCEEEECCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEHHHHHHHHHHHCCCHH
LDALDFLGDARAAAAQVGLSDAMLNRSMNEGFSGGERKRNELLQLALLCPRLAMLDEIDS
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
GMDVDGVRAAVALIGRLREQGTAFVIVSHYLQMIEALAPDTVLLLDRGRIAESGDLALAR
CCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHH
DIAAKGFARSDALAQA
HHHHHCCCCCHHHHCC
>Mature Secondary Structure
MNRSEPLLQVFDLSVEVAKRRVLQSVSLAVPAGALVVLMGANGSGKSTLGMTLAGHPAYR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEEECCCCCC
ATHGHVRFGGQDLLAMSVQERARAGLFLSFQAPPDIPGVKNNLFIRTALNAVREARGDTA
CCCCEEEECCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEHHHHHHHHHHHCCCHH
LDALDFLGDARAAAAQVGLSDAMLNRSMNEGFSGGERKRNELLQLALLCPRLAMLDEIDS
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
GMDVDGVRAAVALIGRLREQGTAFVIVSHYLQMIEALAPDTVLLLDRGRIAESGDLALAR
CCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHH
DIAAKGFARSDALAQA
HHHHHCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]