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The map label for this gene is hutF [H]

Identifier: 237813079

GI number: 237813079

Start: 2775399

End: 2776781

Strand: Reverse

Name: hutF [H]

Synonym: GBP346_A2841

Alternate gene names: 237813079

Gene position: 2776781-2775399 (Counterclockwise)

Preceding gene: 237813080

Following gene: 237813078

Centisome position: 67.75

GC content: 71.95

Gene sequence:

>1383_bases
ATGACGAAAATCGATTCGATGTTGTTTGCCGAGCAGGCGTATCTGCCGGGCGGCTGGCGGCGCGACGTGCTGCTGCGCTG
GAACGCGGCGGGCGCGCTCGTCGACGTGAGCGCGGATGCGGCGGCGCCCGCGGGCGTCGCGCGCGCGAACGGGCCGCTGT
TGCCGGGCATGCCGAACCTGCACTCGCACGCGTTTCAGCGCGCGATGGCGGGGCTCACCGAATATCGCGCGAACCCGTCC
GACACGTTCTGGAGCTGGCGCGACCTGATGTACCGCTTCGCGCTGAAGATCACGCCCGACGCGCTCGCCGCGGTCGCGCG
CTGGCTCTATGTCGAGATGCTGAAAAGCGGCTACACGTCGGTGTGCGAATTCCATTACGTTCATCACGCACCGGACGGCG
CGCGCTATGCGCGGCCCGCGGAGCTGGCGGCGCGCGTGGTCGGCGCGGCGCGGGACGCGGGCATCGGCATCACGATGCTG
CCGGTCGCGTATCAGTACAGCGGCTTCGGCGAGCGCGCGCCGCGCGACGACCAGCGTCGTTTCATCAATACGCCCGACGC
GCTGCTCGCGCTGGTCGACGCGTTGCGCGGCGAGTTGCCCGAGCATGGCGGGCTGCGCTACGGCATCGCGCCGCACTCGC
TGCGCGCGGTGTCGGAAAGCGGGCTGCGAGCGCTCGTTGGCGCGATGCCGGCCGATGCGCCGGTGCACATCCATATCGCC
GAGCAGACCGCGGAAGTCGACGATTGCATGCGCGCGTACGGCGCGCGGCCGGTGCGGTGGCTCCTCGAGCGCTTCGACGT
GAACGCGCGCTGGTGCCTCGTGCACGCGACGCATCTCGACGCCGCCGAGACGCAGGCGCTCGCACGCAGCGGCGCGACCG
CGGGCCTGTGCCCGACGACCGAGGCGAATCTCGGCGACGGCATTTTTCCGGCGGTCGACTATCTCGCGGCGGGCGGCGCG
ATCGGCATCGGTTCGGACAGCCACGCGAGCGTCGACTGGCGCGCCGAGTTGCGGCTCTTCGAATACGGGCAGCGGCTCGT
GCGGCGCGAGCGCAACGTGCTTGCCGACGCGGCGCAGACGCGCGTGGCGGACCGGCTGTTCGCGGCGTCGCTCGCGGGCG
GCGCGCGCGCGGCCGGGCGTGCCGTCGGCGCGCTCGAGGCGGGCCGACGCGCCGACTGGATCGTGCTCGATCCCGCGCAT
CCGTCGATCGCCGAGCACGGCAGCGACACGTGGCTGTCGGGCGCGGTGTTCGCCGAGCACGGCGACACGCCGGTGCTCGA
CGTGTACGTCGGCGGCGAGCGGGTGGTGAACGCGCGCAGGCATCGCGACGAAGAAGCGGCGTATGCCGGATATCGCGCGG
CGCTCGCGCAACTATTGAGCTGA

Upstream 100 bases:

>100_bases
GCCGAGCTCGCGTACTGGTTCGGCCGGCCGCTGTGCGAGCGGGTCGTGAAGGGCGGCGTGACGGTGTTCACGCGCGATGC
GCGCTGACCGGACGATGAGC

Downstream 100 bases:

>100_bases
AGCGCGGCGGCGTTGCGCGAACGCCGGACGCTACGAACGGACGGCGGCGCGGATGGCCTGCGGCGCGGTCAGCATGACTC
CGGCGCGCGGCGTCGAGCGC

Product: N-formimino-L-glutamate deiminase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MTKIDSMLFAEQAYLPGGWRRDVLLRWNAAGALVDVSADAAAPAGVARANGPLLPGMPNLHSHAFQRAMAGLTEYRANPS
DTFWSWRDLMYRFALKITPDALAAVARWLYVEMLKSGYTSVCEFHYVHHAPDGARYARPAELAARVVGAARDAGIGITML
PVAYQYSGFGERAPRDDQRRFINTPDALLALVDALRGELPEHGGLRYGIAPHSLRAVSESGLRALVGAMPADAPVHIHIA
EQTAEVDDCMRAYGARPVRWLLERFDVNARWCLVHATHLDAAETQALARSGATAGLCPTTEANLGDGIFPAVDYLAAGGA
IGIGSDSHASVDWRAELRLFEYGQRLVRRERNVLADAAQTRVADRLFAASLAGGARAAGRAVGALEAGRRADWIVLDPAH
PSIAEHGSDTWLSGAVFAEHGDTPVLDVYVGGERVVNARRHRDEEAAYAGYRAALAQLLS

Sequences:

>Translated_460_residues
MTKIDSMLFAEQAYLPGGWRRDVLLRWNAAGALVDVSADAAAPAGVARANGPLLPGMPNLHSHAFQRAMAGLTEYRANPS
DTFWSWRDLMYRFALKITPDALAAVARWLYVEMLKSGYTSVCEFHYVHHAPDGARYARPAELAARVVGAARDAGIGITML
PVAYQYSGFGERAPRDDQRRFINTPDALLALVDALRGELPEHGGLRYGIAPHSLRAVSESGLRALVGAMPADAPVHIHIA
EQTAEVDDCMRAYGARPVRWLLERFDVNARWCLVHATHLDAAETQALARSGATAGLCPTTEANLGDGIFPAVDYLAAGGA
IGIGSDSHASVDWRAELRLFEYGQRLVRRERNVLADAAQTRVADRLFAASLAGGARAAGRAVGALEAGRRADWIVLDPAH
PSIAEHGSDTWLSGAVFAEHGDTPVLDVYVGGERVVNARRHRDEEAAYAGYRAALAQLLS
>Mature_459_residues
TKIDSMLFAEQAYLPGGWRRDVLLRWNAAGALVDVSADAAAPAGVARANGPLLPGMPNLHSHAFQRAMAGLTEYRANPSD
TFWSWRDLMYRFALKITPDALAAVARWLYVEMLKSGYTSVCEFHYVHHAPDGARYARPAELAARVVGAARDAGIGITMLP
VAYQYSGFGERAPRDDQRRFINTPDALLALVDALRGELPEHGGLRYGIAPHSLRAVSESGLRALVGAMPADAPVHIHIAE
QTAEVDDCMRAYGARPVRWLLERFDVNARWCLVHATHLDAAETQALARSGATAGLCPTTEANLGDGIFPAVDYLAAGGAI
GIGSDSHASVDWRAELRLFEYGQRLVRRERNVLADAAQTRVADRLFAASLAGGARAAGRAVGALEAGRRADWIVLDPAHP
SIAEHGSDTWLSGAVFAEHGDTPVLDVYVGGERVVNARRHRDEEAAYAGYRAALAQLLS

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17540282, Length=425, Percent_Identity=30.3529411764706, Blast_Score=201, Evalue=9e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 49630; Mature: 49498

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIDSMLFAEQAYLPGGWRRDVLLRWNAAGALVDVSADAAAPAGVARANGPLLPGMPNL
CCCHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCCH
HSHAFQRAMAGLTEYRANPSDTFWSWRDLMYRFALKITPDALAAVARWLYVEMLKSGYTS
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHH
VCEFHYVHHAPDGARYARPAELAARVVGAARDAGIGITMLPVAYQYSGFGERAPRDDQRR
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHHCCCCCCCCCCCCHHHH
FINTPDALLALVDALRGELPEHGGLRYGIAPHSLRAVSESGLRALVGAMPADAPVHIHIA
HCCCHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEC
EQTAEVDDCMRAYGARPVRWLLERFDVNARWCLVHATHLDAAETQALARSGATAGLCPTT
CHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCCCCCCCCCCC
EANLGDGIFPAVDYLAAGGAIGIGSDSHASVDWRAELRLFEYGQRLVRRERNVLADAAQT
CCCCCCCHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVADRLFAASLAGGARAAGRAVGALEAGRRADWIVLDPAHPSIAEHGSDTWLSGAVFAEH
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHCCCCCEECCEEEECC
GDTPVLDVYVGGERVVNARRHRDEEAAYAGYRAALAQLLS
CCCCEEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TKIDSMLFAEQAYLPGGWRRDVLLRWNAAGALVDVSADAAAPAGVARANGPLLPGMPNL
CCHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCCH
HSHAFQRAMAGLTEYRANPSDTFWSWRDLMYRFALKITPDALAAVARWLYVEMLKSGYTS
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHH
VCEFHYVHHAPDGARYARPAELAARVVGAARDAGIGITMLPVAYQYSGFGERAPRDDQRR
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHHCCCCCCCCCCCCHHHH
FINTPDALLALVDALRGELPEHGGLRYGIAPHSLRAVSESGLRALVGAMPADAPVHIHIA
HCCCHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEC
EQTAEVDDCMRAYGARPVRWLLERFDVNARWCLVHATHLDAAETQALARSGATAGLCPTT
CHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCCCCCCCCCCC
EANLGDGIFPAVDYLAAGGAIGIGSDSHASVDWRAELRLFEYGQRLVRRERNVLADAAQT
CCCCCCCHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVADRLFAASLAGGARAAGRAVGALEAGRRADWIVLDPAHPSIAEHGSDTWLSGAVFAEH
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHCCCCCEECCEEEECC
GDTPVLDVYVGGERVVNARRHRDEEAAYAGYRAALAQLLS
CCCCEEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA