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The map label for this gene is hutI [H]

Identifier: 237813080

GI number: 237813080

Start: 2776795

End: 2778018

Strand: Reverse

Name: hutI [H]

Synonym: GBP346_A2842

Alternate gene names: 237813080

Gene position: 2778018-2776795 (Counterclockwise)

Preceding gene: 237813081

Following gene: 237813079

Centisome position: 67.78

GC content: 71.98

Gene sequence:

>1224_bases
ATGAAATCGATTCTCTGGCACAACCTGAAGCTGTGCGCGCACGGCGACCCGAACGACACGATCGCGGATGCGGCGATCGC
GGTGAACGGCGACGGCACGATCGCCTGGACCGGGCGCGCGAGCGACGTGCCGGCCGGCTACGTGCACTGGCCGCGCGAGG
ACCTGCGCGGCGCATGGGTGACGCCCGGCCTCGTCGATTGCCACACGCACCTCGTCTACGGCGGCCAGCGCGCGGACGAG
TTCGCGCAGCGCCTGGCGGGGGCGAGCTACGAGGAGATCGCGCGGCGCGGCGGCGGCATCGTATCGACCGTGCGCGCGAC
GCGCGACGCGAGCGAGGCGGCGCTGTTCGAGCAGGCATGCGCGCGGCTGCGGCCGCTCCTTGCCGAGGGCGTGACCGCGA
TCGAGATCAAGTCCGGCTACGGGCTCGAACTCGCGAGCGAGCGGCGGATGCTGCGCGTCGCGCGGCAGCTCGGCGAGCGC
TTTCCGGTGAGCGTCTATACGACGTTCCTCGGCGCGCACGCGCTGCCGCCCGAGTACGCGGGCCGCGCGGACGAATATAT
CGACGAGGTTTGCGAACGGATGCTGCCCGCGCTTGCCGACGAAGGGCTCGTCGACGCGGTCGACGTGTTTTGCGAGCGGA
TCGGCTTCACGCTCGCGCAGAGCGAGCGCGTGTTCGAAGCGGCGGCGCGGCGCGGGCTGCCCGTCAAGATGCACGCGGAG
CAGTTGTCGAACGGCGGCGGCTCCGCGCTCGCCGCGCGCTATCGCGCGCTGTCGGCCGACCACCTCGAATATCTGGACGC
GGCGGGCGTCGCCGCGATGCGTGCATCGGGCACGACGGCCGTGCTGCTGCCGGGCGCGTACTACTTCATCCGCGAGACGA
AGCTGCCGCCGATCGATCTGCTGCGCCGCCACGGCGTGCCGATCGCGCTCGCGACCGATCACAATCCGGGCACCTCGCCG
CTCACGTCGCTGCTGCTCACGATGAACATGGGCTGCACGGTGTTCAAGCTGACCGTGCAGGAGGCGCTCCTCGGCGTCAC
GCGCCACGCGGCGGCGGCGCTCGGCGCGAGCGACCGGCACGGCTCGCTCGCGCCCGGGCGGCAGGCGGATTTCGCGGTAT
GGCCGGTCTCGACGCTCGCCGAGCTCGCGTACTGGTTCGGCCGGCCGCTGTGCGAGCGGGTCGTGAAGGGCGGCGTGACG
GTGTTCACGCGCGATGCGCGCTGA

Upstream 100 bases:

>100_bases
CGTGCGCGCACGGCGAGTTCCGATGCGCGATTCGCGGCGAAGGCGTGCTCCTCGCCGTCGGCGTGACGCTTCTTCAAGAC
AACGCACAAGGCTCGATCGA

Downstream 100 bases:

>100_bases
CCGGACGATGAGCATGACGAAAATCGATTCGATGTTGTTTGCCGAGCAGGCGTATCTGCCGGGCGGCTGGCGGCGCGACG
TGCTGCTGCGCTGGAACGCG

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MKSILWHNLKLCAHGDPNDTIADAAIAVNGDGTIAWTGRASDVPAGYVHWPREDLRGAWVTPGLVDCHTHLVYGGQRADE
FAQRLAGASYEEIARRGGGIVSTVRATRDASEAALFEQACARLRPLLAEGVTAIEIKSGYGLELASERRMLRVARQLGER
FPVSVYTTFLGAHALPPEYAGRADEYIDEVCERMLPALADEGLVDAVDVFCERIGFTLAQSERVFEAAARRGLPVKMHAE
QLSNGGGSALAARYRALSADHLEYLDAAGVAAMRASGTTAVLLPGAYYFIRETKLPPIDLLRRHGVPIALATDHNPGTSP
LTSLLLTMNMGCTVFKLTVQEALLGVTRHAAAALGASDRHGSLAPGRQADFAVWPVSTLAELAYWFGRPLCERVVKGGVT
VFTRDAR

Sequences:

>Translated_407_residues
MKSILWHNLKLCAHGDPNDTIADAAIAVNGDGTIAWTGRASDVPAGYVHWPREDLRGAWVTPGLVDCHTHLVYGGQRADE
FAQRLAGASYEEIARRGGGIVSTVRATRDASEAALFEQACARLRPLLAEGVTAIEIKSGYGLELASERRMLRVARQLGER
FPVSVYTTFLGAHALPPEYAGRADEYIDEVCERMLPALADEGLVDAVDVFCERIGFTLAQSERVFEAAARRGLPVKMHAE
QLSNGGGSALAARYRALSADHLEYLDAAGVAAMRASGTTAVLLPGAYYFIRETKLPPIDLLRRHGVPIALATDHNPGTSP
LTSLLLTMNMGCTVFKLTVQEALLGVTRHAAAALGASDRHGSLAPGRQADFAVWPVSTLAELAYWFGRPLCERVVKGGVT
VFTRDAR
>Mature_407_residues
MKSILWHNLKLCAHGDPNDTIADAAIAVNGDGTIAWTGRASDVPAGYVHWPREDLRGAWVTPGLVDCHTHLVYGGQRADE
FAQRLAGASYEEIARRGGGIVSTVRATRDASEAALFEQACARLRPLLAEGVTAIEIKSGYGLELASERRMLRVARQLGER
FPVSVYTTFLGAHALPPEYAGRADEYIDEVCERMLPALADEGLVDAVDVFCERIGFTLAQSERVFEAAARRGLPVKMHAE
QLSNGGGSALAARYRALSADHLEYLDAAGVAAMRASGTTAVLLPGAYYFIRETKLPPIDLLRRHGVPIALATDHNPGTSP
LTSLLLTMNMGCTVFKLTVQEALLGVTRHAAAALGASDRHGSLAPGRQADFAVWPVSTLAELAYWFGRPLCERVVKGGVT
VFTRDAR

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family [H]

Homologues:

Organism=Homo sapiens, GI223972677, Length=389, Percent_Identity=35.73264781491, Blast_Score=211, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17555004, Length=427, Percent_Identity=32.7868852459016, Blast_Score=218, Evalue=6e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.7 [H]

Molecular weight: Translated: 43815; Mature: 43815

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSILWHNLKLCAHGDPNDTIADAAIAVNGDGTIAWTGRASDVPAGYVHWPREDLRGAWV
CCCCHHCCEEEEECCCCCCCCCCEEEEECCCCEEEECCCCCCCCCCCEECCHHHCCCCCC
TPGLVDCHTHLVYGGQRADEFAQRLAGASYEEIARRGGGIVSTVRATRDASEAALFEQAC
CCCHHHHHHHHEECCCHHHHHHHHHCCCCHHHHHHHCCCEEEHHHHHCCHHHHHHHHHHH
ARLRPLLAEGVTAIEIKSGYGLELASERRMLRVARQLGERFPVSVYTTFLGAHALPPEYA
HHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHC
GRADEYIDEVCERMLPALADEGLVDAVDVFCERIGFTLAQSERVFEAAARRGLPVKMHAE
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEHH
QLSNGGGSALAARYRALSADHLEYLDAAGVAAMRASGTTAVLLPGAYYFIRETKLPPIDL
HHCCCCCHHHHHHHHHHCHHHHHHHHHHCHHHHCCCCCEEEEECCEEEEEECCCCCHHHH
LRRHGVPIALATDHNPGTSPLTSLLLTMNMGCTVFKLTVQEALLGVTRHAAAALGASDRH
HHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCC
GSLAPGRQADFAVWPVSTLAELAYWFGRPLCERVVKGGVTVFTRDAR
CCCCCCCCCCEEEECHHHHHHHHHHHCCHHHHHHHHCCCEEEEECCC
>Mature Secondary Structure
MKSILWHNLKLCAHGDPNDTIADAAIAVNGDGTIAWTGRASDVPAGYVHWPREDLRGAWV
CCCCHHCCEEEEECCCCCCCCCCEEEEECCCCEEEECCCCCCCCCCCEECCHHHCCCCCC
TPGLVDCHTHLVYGGQRADEFAQRLAGASYEEIARRGGGIVSTVRATRDASEAALFEQAC
CCCHHHHHHHHEECCCHHHHHHHHHCCCCHHHHHHHCCCEEEHHHHHCCHHHHHHHHHHH
ARLRPLLAEGVTAIEIKSGYGLELASERRMLRVARQLGERFPVSVYTTFLGAHALPPEYA
HHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHC
GRADEYIDEVCERMLPALADEGLVDAVDVFCERIGFTLAQSERVFEAAARRGLPVKMHAE
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEHH
QLSNGGGSALAARYRALSADHLEYLDAAGVAAMRASGTTAVLLPGAYYFIRETKLPPIDL
HHCCCCCHHHHHHHHHHCHHHHHHHHHHCHHHHCCCCCEEEEECCEEEEEECCCCCHHHH
LRRHGVPIALATDHNPGTSPLTSLLLTMNMGCTVFKLTVQEALLGVTRHAAAALGASDRH
HHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCC
GSLAPGRQADFAVWPVSTLAELAYWFGRPLCERVVKGGVTVFTRDAR
CCCCCCCCCCEEEECHHHHHHHHHHHCCHHHHHHHHCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA