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The map label for this gene is narL [H]

Identifier: 237813049

GI number: 237813049

Start: 2744071

End: 2744772

Strand: Direct

Name: narL [H]

Synonym: GBP346_A2810

Alternate gene names: 237813049

Gene position: 2744071-2744772 (Clockwise)

Preceding gene: 237813048

Following gene: 237813050

Centisome position: 66.95

GC content: 69.23

Gene sequence:

>702_bases
ATGACCATACGGGTACTGTTGATCGACGACCACACGCTCTTTCGCAGCGGCGTCAAGCTGCTGCTGCAGCGCCAGCCGGA
TTTCGAAGTCGTCGACGAGGCGTCCGACGGCGTCGAGGGCGTGAAGCGCGCGAAGCAGCATCAGCCGGACGTGATCCTGC
TCGATCTGAACATGCCGGGGCTATCGGGGCTCGAGACGCTGCAACTGCTCGTGCAGGACGTGCCGTCCGCGCACGTCGTG
ATCCTCACGGTGTCGGAAGACGCGGAAGAGCTGACGACCGCGCTGCGCGACGGCGCGTGCGGCTTCCTCGTGAAGAACAT
CGACGCGGAGACGCTCGTCGCGGGCATCCGCAAGGCTGCCGCGGGCGAGCCCGTGATCGCCGAGAGCATGACCGCGAAGT
GGATCGCGAGCCTGCGCGCGCCGGTGCCCGCCGCGCGGCCCGCGCCGGCCGCCGCGCTCGCGCCGGCCGCGCACGCGTCG
GTCGATCCCGACCAGTTGACGCCGCGCGAGCACGACATCGTGCGCGCGCTCGCGCGCGGCGCGAGCAACAAGGAGATCGC
GCGCGAGTTCGACGTCGCCGAAAGCACGGTGAAGATCCACGTGCAGAACGTCCTGAAGAAGCTGAACCTGTCGAGCCGCG
TGCAGATCGCCGTGTATGCGGTCGAGCGCGGGCTCACCGCGCCGCATCCGGCCGAGGCATAA

Upstream 100 bases:

>100_bases
TCACGTTGACGGGCGCGCCGCAGCGCGGCGCGCGCGTCGAGCTGGTGCTGCCGGCCGACGCGCGACAGGCGGCATAGCAA
CGAGAACGAGGACAATAATC

Downstream 100 bases:

>100_bases
GCGGAAACGCCCGAGGGGACGCCGGCCGCGGCCCCGAGCGGCGCGGCGCCGGCGGCCCGCCGCGGCGGCGTCTCGCCCCC
CTTTCCCGTCGGCCGCGGCG

Product: transcriptional regulatory protein DegU (Protease production enhancerprotein)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MTIRVLLIDDHTLFRSGVKLLLQRQPDFEVVDEASDGVEGVKRAKQHQPDVILLDLNMPGLSGLETLQLLVQDVPSAHVV
ILTVSEDAEELTTALRDGACGFLVKNIDAETLVAGIRKAAAGEPVIAESMTAKWIASLRAPVPAARPAPAAALAPAAHAS
VDPDQLTPREHDIVRALARGASNKEIAREFDVAESTVKIHVQNVLKKLNLSSRVQIAVYAVERGLTAPHPAEA

Sequences:

>Translated_233_residues
MTIRVLLIDDHTLFRSGVKLLLQRQPDFEVVDEASDGVEGVKRAKQHQPDVILLDLNMPGLSGLETLQLLVQDVPSAHVV
ILTVSEDAEELTTALRDGACGFLVKNIDAETLVAGIRKAAAGEPVIAESMTAKWIASLRAPVPAARPAPAAALAPAAHAS
VDPDQLTPREHDIVRALARGASNKEIAREFDVAESTVKIHVQNVLKKLNLSSRVQIAVYAVERGLTAPHPAEA
>Mature_232_residues
TIRVLLIDDHTLFRSGVKLLLQRQPDFEVVDEASDGVEGVKRAKQHQPDVILLDLNMPGLSGLETLQLLVQDVPSAHVVI
LTVSEDAEELTTALRDGACGFLVKNIDAETLVAGIRKAAAGEPVIAESMTAKWIASLRAPVPAARPAPAAALAPAAHASV
DPDQLTPREHDIVRALARGASNKEIAREFDVAESTVKIHVQNVLKKLNLSSRVQIAVYAVERGLTAPHPAEA

Specific function: This protein activates the expression of the nitrate reductase (narGHJI) and formate dehydrogenase-N (fdnGHI) operons and represses the transcription of the fumarate reductase (frdABCD) operon in response to a nitrate/nitrite induction signal transmitted

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1787473, Length=215, Percent_Identity=46.5116279069767, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI1788521, Length=223, Percent_Identity=38.5650224215247, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1788222, Length=224, Percent_Identity=28.125, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1790102, Length=215, Percent_Identity=31.6279069767442, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786747, Length=216, Percent_Identity=25.462962962963, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI1788712, Length=218, Percent_Identity=22.9357798165138, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082052, Length=126, Percent_Identity=34.9206349206349, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24921; Mature: 24790

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRVLLIDDHTLFRSGVKLLLQRQPDFEVVDEASDGVEGVKRAKQHQPDVILLDLNMPG
CEEEEEEECCHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCC
LSGLETLQLLVQDVPSAHVVILTVSEDAEELTTALRDGACGFLVKNIDAETLVAGIRKAA
CCHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCEEHHHCCCHHHHHHHHHHHC
AGEPVIAESMTAKWIASLRAPVPAARPAPAAALAPAAHASVDPDQLTPREHDIVRALARG
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCHHHCCCCHHHHHHHHHCC
ASNKEIAREFDVAESTVKIHVQNVLKKLNLSSRVQIAVYAVERGLTAPHPAEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
TIRVLLIDDHTLFRSGVKLLLQRQPDFEVVDEASDGVEGVKRAKQHQPDVILLDLNMPG
EEEEEEECCHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCC
LSGLETLQLLVQDVPSAHVVILTVSEDAEELTTALRDGACGFLVKNIDAETLVAGIRKAA
CCHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCEEHHHCCCHHHHHHHHHHHC
AGEPVIAESMTAKWIASLRAPVPAARPAPAAALAPAAHASVDPDQLTPREHDIVRALARG
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCHHHCCCCHHHHHHHHHCC
ASNKEIAREFDVAESTVKIHVQNVLKKLNLSSRVQIAVYAVERGLTAPHPAEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]