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The map label for this gene is aceE [H]

Identifier: 237813032

GI number: 237813032

Start: 2720062

End: 2722758

Strand: Reverse

Name: aceE [H]

Synonym: GBP346_A2792

Alternate gene names: 237813032

Gene position: 2722758-2720062 (Counterclockwise)

Preceding gene: 237813033

Following gene: 237813031

Centisome position: 66.43

GC content: 65.41

Gene sequence:

>2697_bases
ATGTCCGCTGTACCGAATGAAGTGATGAAGTACGTCGCAGCCGAACGCGACGACGACGCGCAGGAAACCGTCGAATGGCT
CGAAGCGCTCGACGGCGTGATTTCGTCGGTCGGCCCCGGCCGCGCGCACTACCTGATCGAAAAGCAGATCGAATTCGCGC
GCATGCACGGCGAGCACTTGCCGTTCTCCGCGAACACCCCGTACATCAACACGATTCCCGTCGAAGCCCAGGCGAAGATT
CCGGGCGACCAGGACATCGAGCACCGGATCCGCTCGTACACGCGCTGGAACGCGATCGCGATGGTGCTGCGCGCGGGCAA
GCACACGAACGTCGGCGGCCACATCGCGTCGTTCGCTTCGGCCGCGACGCTCTATGACGTCGGCTACAACCACTTCTGGC
ACGCGCCGTCCGCCGAGCACGGCGGCGATCTCGTGTTCGTGCAGGGCCATTCGTCGCCCGGCATTTACTCGCGCGCGTTC
CTGCTCGGCCGCCTGACGGAAGATCAGCTCGACAACTTCCGCCAGGAAGTGGGCGGCAACGGCATCTCATCGTATCCGCA
CCCGTGGCTGATGCCGGATTTCTGGCAGTTCCCGACCGTGTCGATGGGCCTCGGTCCCATCATGGCGATCTATCAGGCGC
GCTTCATGAAGTACCTGCAGGCGCGCGGGATCGTGAAGACGGAAGGCCGCAAGGTCTGGGCGTTCCTCGGCGACGGCGAG
ACCGACGAGCCGGAATCGCTCGGCGCGATCGGCATGGCGAGCCGCGAGAAGCTCGATAACCTCGTGTTCGTGATCAACTG
CAACCTGCAGCGTCTCGACGGCCCGGTGCGCGGCAACGGCAAGATCATCCAGGAGCTCGAATCGGAGTTCCGCGGCGCCG
GCTGGAACGTGATCAAGGTGATCTGGGGCAGCCGCTGGGATGCGCTGTTCGCGCGCGACAAGACGGGCGCGCTGATGCGC
CGGATGATGGAAGCCGTCGACGGCGAGTATCAGACGTACAAGTCGGAGTCGGGCGCGTACGTGCGCGAGCACTTCTTCAA
CACGCCGGAGCTGAAGGCGCTCGTCGCCGACTGGTCCGACGACGACATCTGGAACCTGAACCGCGGCGGCCACGATCCGC
ACAAGATCTACGCGGCGTTCCACGAGGCGAGCAATTCGAAGGGCGCGCCGACGGTGATCCTTGCGAAGACGATCAAGGGC
TACGGGATGGGCGAAGCCGGCCAGGCGATGAACATCACGCACCAGCAGAAGAAGTTGCCCGTCGAGCAACTGAAGAAGTT
CCGCGACCAGTTCCGCCTGCCGATCGCCGACGACGTGATCGCCGACGTGCCGTACCTGAAGTTCGACGAAGGCTCGAAGG
AACTCGAGTACATGCGCGCGCACCGCCAGGCGCTCGGCGGCTATCTGCCGCAGCGCCGCCAGAAGGCGCAATCGCTGCCG
GTGCCGGCGCTCGACGCGTTCGAGCCGCTGCTCAAGGGCACGGGCGAAGGCCGCGAGATCTCGACGACGATGGCGTTCGT
GCGGATCCTGAACATCCTGCTGAAGGACAAGGCGCTCGGCAAGCGCGTCGTGCCGATCGTGCCGGACGAATCGCGCACGT
TCGGCATGGAGGGCCTGTTCCGCCAGATCGGCATCTGGAACCAGGAAGGCCAGAAGTATGTGCCGGAAGATTCCGATCAA
CTGATGTTCTACAAGGAATCGGAAACCGGCCAGATCCTGCAGGAAGGCATCAACGAAGCGGGCGGCATGTGCGACTGGAT
CGCGGCGGCGACGTCGTACTCGACGCACGGCGAGATCATGGTGCCGTTCTATATCTTCTATTCGATGTTCGGCTTCCAGC
GCATCGGCGATCTCGCGTGGGCGGCGGGCGACATGCGCTCGCGCGGTTTCCTGCTCGGCGGCACCGCGGGCCGCACGACG
CTCAACGGCGAAGGCCTGCAGCACGAAGACGGCCACTCGCTGATGTGGGCGGCTTCGGTGCCGAACTGCGTGAGCTACGA
TCCGACGTTCGGCTACGAGCTCGCCGTCATCGTGCAGGACGGCCTGCGCCGGATGGTGCAGGAGCAGGAGGACGTCTATT
ACTACGTGACGGTGATGAACGAGAACTACGAGCACCCGGCGATTCCGCAGGGCGAGCACGTGGCGGCCGACATCATCAAG
GGCATGTACGCGTTCAGGAAGGCCGACGCCGACAAGAAGGCGCCGCGCGTGCAACTGCTCGGCGCGGGCACGATCTTCAA
CGAAGTGATCGCCGCGGCGGACCTGCTGAAGAACGACTGGGGCGTCGCCGCCGATCTCTGGAGCGTGCCGAGCTTCACCG
AGCTCGCGCGCGAAGGCCATGACGTCGAGCGCTGGAACCTGCTGCATCCGGCCGAGGCGCGCCGCCTGTCGCACGTGCAG
ACGTGCCTGAAGGACACGCAGGGCCCGGTGATCGCGTCGACCGACTACGTCCGCGCGCTCGCCGACCAGATCCGCGGCCA
GATCGACCGCCGCTACGTCGTGCTCGGCACCGACGGCTTCGGCCGCTCGGACACGCGCGGCGCGCTGCGCCACTTCTTCG
AGGTGGACCGCTACTGGGTCACGGTCGCGGCGCTCAACGCGCTCGCCGATGAAGGCACGATCGAGCGCAAGGTCGTCGCC
GACGCCATCGCGAAGTACAACCTCGACCCGGCCAAGCCCAACCCGATGACGGTTTAA

Upstream 100 bases:

>100_bases
CCCGCAACGCTCTTTACAATCCGCGGGAGCTTGTTGCAGCTGGCGGCATGCGTCGTCGCGCGAAGGCCATCTTCAATTCC
AGGACACCCAGGAGACGAGA

Downstream 100 bases:

>100_bases
CGCACGCGCCGCGCGAGCCGCGCGCCCGCTCCCGCTGTCGACGTTTTCGACGAACGAAGCGGAGGCGGGTGGCGCGGCTG
CGCCTTGCATGGGATCGGAG

Product: pyruvate dehydrogenase subunit E1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 898; Mature: 897

Protein sequence:

>898_residues
MSAVPNEVMKYVAAERDDDAQETVEWLEALDGVISSVGPGRAHYLIEKQIEFARMHGEHLPFSANTPYINTIPVEAQAKI
PGDQDIEHRIRSYTRWNAIAMVLRAGKHTNVGGHIASFASAATLYDVGYNHFWHAPSAEHGGDLVFVQGHSSPGIYSRAF
LLGRLTEDQLDNFRQEVGGNGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLQARGIVKTEGRKVWAFLGDGE
TDEPESLGAIGMASREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVIWGSRWDALFARDKTGALMR
RMMEAVDGEYQTYKSESGAYVREHFFNTPELKALVADWSDDDIWNLNRGGHDPHKIYAAFHEASNSKGAPTVILAKTIKG
YGMGEAGQAMNITHQQKKLPVEQLKKFRDQFRLPIADDVIADVPYLKFDEGSKELEYMRAHRQALGGYLPQRRQKAQSLP
VPALDAFEPLLKGTGEGREISTTMAFVRILNILLKDKALGKRVVPIVPDESRTFGMEGLFRQIGIWNQEGQKYVPEDSDQ
LMFYKESETGQILQEGINEAGGMCDWIAAATSYSTHGEIMVPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTT
LNGEGLQHEDGHSLMWAASVPNCVSYDPTFGYELAVIVQDGLRRMVQEQEDVYYYVTVMNENYEHPAIPQGEHVAADIIK
GMYAFRKADADKKAPRVQLLGAGTIFNEVIAAADLLKNDWGVAADLWSVPSFTELAREGHDVERWNLLHPAEARRLSHVQ
TCLKDTQGPVIASTDYVRALADQIRGQIDRRYVVLGTDGFGRSDTRGALRHFFEVDRYWVTVAALNALADEGTIERKVVA
DAIAKYNLDPAKPNPMTV

Sequences:

>Translated_898_residues
MSAVPNEVMKYVAAERDDDAQETVEWLEALDGVISSVGPGRAHYLIEKQIEFARMHGEHLPFSANTPYINTIPVEAQAKI
PGDQDIEHRIRSYTRWNAIAMVLRAGKHTNVGGHIASFASAATLYDVGYNHFWHAPSAEHGGDLVFVQGHSSPGIYSRAF
LLGRLTEDQLDNFRQEVGGNGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLQARGIVKTEGRKVWAFLGDGE
TDEPESLGAIGMASREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVIWGSRWDALFARDKTGALMR
RMMEAVDGEYQTYKSESGAYVREHFFNTPELKALVADWSDDDIWNLNRGGHDPHKIYAAFHEASNSKGAPTVILAKTIKG
YGMGEAGQAMNITHQQKKLPVEQLKKFRDQFRLPIADDVIADVPYLKFDEGSKELEYMRAHRQALGGYLPQRRQKAQSLP
VPALDAFEPLLKGTGEGREISTTMAFVRILNILLKDKALGKRVVPIVPDESRTFGMEGLFRQIGIWNQEGQKYVPEDSDQ
LMFYKESETGQILQEGINEAGGMCDWIAAATSYSTHGEIMVPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTT
LNGEGLQHEDGHSLMWAASVPNCVSYDPTFGYELAVIVQDGLRRMVQEQEDVYYYVTVMNENYEHPAIPQGEHVAADIIK
GMYAFRKADADKKAPRVQLLGAGTIFNEVIAAADLLKNDWGVAADLWSVPSFTELAREGHDVERWNLLHPAEARRLSHVQ
TCLKDTQGPVIASTDYVRALADQIRGQIDRRYVVLGTDGFGRSDTRGALRHFFEVDRYWVTVAALNALADEGTIERKVVA
DAIAKYNLDPAKPNPMTV
>Mature_897_residues
SAVPNEVMKYVAAERDDDAQETVEWLEALDGVISSVGPGRAHYLIEKQIEFARMHGEHLPFSANTPYINTIPVEAQAKIP
GDQDIEHRIRSYTRWNAIAMVLRAGKHTNVGGHIASFASAATLYDVGYNHFWHAPSAEHGGDLVFVQGHSSPGIYSRAFL
LGRLTEDQLDNFRQEVGGNGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLQARGIVKTEGRKVWAFLGDGET
DEPESLGAIGMASREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVIWGSRWDALFARDKTGALMRR
MMEAVDGEYQTYKSESGAYVREHFFNTPELKALVADWSDDDIWNLNRGGHDPHKIYAAFHEASNSKGAPTVILAKTIKGY
GMGEAGQAMNITHQQKKLPVEQLKKFRDQFRLPIADDVIADVPYLKFDEGSKELEYMRAHRQALGGYLPQRRQKAQSLPV
PALDAFEPLLKGTGEGREISTTMAFVRILNILLKDKALGKRVVPIVPDESRTFGMEGLFRQIGIWNQEGQKYVPEDSDQL
MFYKESETGQILQEGINEAGGMCDWIAAATSYSTHGEIMVPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTTL
NGEGLQHEDGHSLMWAASVPNCVSYDPTFGYELAVIVQDGLRRMVQEQEDVYYYVTVMNENYEHPAIPQGEHVAADIIKG
MYAFRKADADKKAPRVQLLGAGTIFNEVIAAADLLKNDWGVAADLWSVPSFTELAREGHDVERWNLLHPAEARRLSHVQT
CLKDTQGPVIASTDYVRALADQIRGQIDRRYVVLGTDGFGRSDTRGALRHFFEVDRYWVTVAALNALADEGTIERKVVAD
AIAKYNLDPAKPNPMTV

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=885, Percent_Identity=59.6610169491525, Blast_Score=1077, Evalue=0.0,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 100330; Mature: 100199

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVPNEVMKYVAAERDDDAQETVEWLEALDGVISSVGPGRAHYLIEKQIEFARMHGEHL
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
PFSANTPYINTIPVEAQAKIPGDQDIEHRIRSYTRWNAIAMVLRAGKHTNVGGHIASFAS
CCCCCCCEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
AATLYDVGYNHFWHAPSAEHGGDLVFVQGHSSPGIYSRAFLLGRLTEDQLDNFRQEVGGN
HHHHHHCCCCCEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCC
GISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLQARGIVKTEGRKVWAFLGDGE
CCCCCCCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCC
TDEPESLGAIGMASREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKV
CCCCHHCCCCCCCCHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEE
IWGSRWDALFARDKTGALMRRMMEAVDGEYQTYKSESGAYVREHFFNTPELKALVADWSD
EECCCCHHHHCCCHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHCCCCCHHHHEEECCCC
DDIWNLNRGGHDPHKIYAAFHEASNSKGAPTVILAKTIKGYGMGEAGQAMNITHQQKKLP
CCCEECCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEHHCCCCCCCCCCCCCCCHHHHCCC
VEQLKKFRDQFRLPIADDVIADVPYLKFDEGSKELEYMRAHRQALGGYLPQRRQKAQSLP
HHHHHHHHHHHCCCCHHHHHHCCCCEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCC
VPALDAFEPLLKGTGEGREISTTMAFVRILNILLKDKALGKRVVPIVPDESRTFGMEGLF
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHH
RQIGIWNQEGQKYVPEDSDQLMFYKESETGQILQEGINEAGGMCDWIAAATSYSTHGEIM
HHHCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEE
VPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTTLNGEGLQHEDGHSLMWAASV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEECCCCCCCCCCCEEEEECCC
PNCVSYDPTFGYELAVIVQDGLRRMVQEQEDVYYYVTVMNENYEHPAIPQGEHVAADIIK
CCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHH
GMYAFRKADADKKAPRVQLLGAGTIFNEVIAAADLLKNDWGVAADLWSVPSFTELAREGH
HHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHCCC
DVERWNLLHPAEARRLSHVQTCLKDTQGPVIASTDYVRALADQIRGQIDRRYVVLGTDGF
CCHHHCCCCCHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHCCCCEEEEEECCCC
GRSDTRGALRHFFEVDRYWVTVAALNALADEGTIERKVVADAIAKYNLDPAKPNPMTV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SAVPNEVMKYVAAERDDDAQETVEWLEALDGVISSVGPGRAHYLIEKQIEFARMHGEHL
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
PFSANTPYINTIPVEAQAKIPGDQDIEHRIRSYTRWNAIAMVLRAGKHTNVGGHIASFAS
CCCCCCCEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
AATLYDVGYNHFWHAPSAEHGGDLVFVQGHSSPGIYSRAFLLGRLTEDQLDNFRQEVGGN
HHHHHHCCCCCEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCC
GISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLQARGIVKTEGRKVWAFLGDGE
CCCCCCCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCC
TDEPESLGAIGMASREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKV
CCCCHHCCCCCCCCHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEE
IWGSRWDALFARDKTGALMRRMMEAVDGEYQTYKSESGAYVREHFFNTPELKALVADWSD
EECCCCHHHHCCCHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHCCCCCHHHHEEECCCC
DDIWNLNRGGHDPHKIYAAFHEASNSKGAPTVILAKTIKGYGMGEAGQAMNITHQQKKLP
CCCEECCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEHHCCCCCCCCCCCCCCCHHHHCCC
VEQLKKFRDQFRLPIADDVIADVPYLKFDEGSKELEYMRAHRQALGGYLPQRRQKAQSLP
HHHHHHHHHHHCCCCHHHHHHCCCCEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCC
VPALDAFEPLLKGTGEGREISTTMAFVRILNILLKDKALGKRVVPIVPDESRTFGMEGLF
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHH
RQIGIWNQEGQKYVPEDSDQLMFYKESETGQILQEGINEAGGMCDWIAAATSYSTHGEIM
HHHCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEE
VPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTTLNGEGLQHEDGHSLMWAASV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEECCCCCCCCCCCEEEEECCC
PNCVSYDPTFGYELAVIVQDGLRRMVQEQEDVYYYVTVMNENYEHPAIPQGEHVAADIIK
CCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHH
GMYAFRKADADKKAPRVQLLGAGTIFNEVIAAADLLKNDWGVAADLWSVPSFTELAREGH
HHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHCCC
DVERWNLLHPAEARRLSHVQTCLKDTQGPVIASTDYVRALADQIRGQIDRRYVVLGTDGF
CCHHHCCCCCHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHCCCCEEEEEECCCC
GRSDTRGALRHFFEVDRYWVTVAALNALADEGTIERKVVADAIAKYNLDPAKPNPMTV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8021225 [H]