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The map label for this gene is phbC_1 [H]

Identifier: 237812525

GI number: 237812525

Start: 2239952

End: 2241772

Strand: Reverse

Name: phbC_1 [H]

Synonym: GBP346_A2274

Alternate gene names: 237812525

Gene position: 2241772-2239952 (Counterclockwise)

Preceding gene: 237812526

Following gene: 237812524

Centisome position: 54.7

GC content: 67.66

Gene sequence:

>1821_bases
ATGCAACAGTTGTTCGAGTCCTGGCTCGGCGCGTGGCGCAGCTTCGCGGACCCGGCCCGGGCGGCCGCGGGCGACGCACC
GTCGCCGTCGCCGTCGCCGTCGCCGTTCGCGGCGTTCCAGCCGCCGCAGCCGTTTGCGTTCGCGATGCCTGCGATGCCGC
CGATGCCGCCGATGCCGGATTGGTCCGGCGCGGCCGCGTCGTTCGCGGGGCTCGCGCCCGTCGCGTCGGTGCCGCCCGCG
CGGCTGCAGAAGCTGCAGGCCGATTATTCGCGCGATTGCCTCGCGCTGATCCAGCAGGCGAGCGCCGCGACGCCGACCGT
TCCCGAGCTGAAGGACCGGCGTTTCAGCGCGGACGCCTGGAAGGCTTCACCCGCGCACGGGTTCGCGGCCGCCTGGTATC
TGCTGAACGCGCGCTACCTGCAGGAGCTCGCCGACGCGCTCGAGACCGACCCGAAGACGCGCGAGCGGATCCGCTTCACG
GTCCAGCAGTGGACGGCCGCCGCGTCGCCGAGCAACTTCCTCGCGCTCAATCCGGAGGCGCAGAAGAATCTCGTCGAGAC
GCAGGGCGAGAGCCTGCGTCTCGGGATGATGAACCTGCTCGCCGACATGCAGCGCGGCAAGATTTCGCAGACGGACGAAT
CGCAATTCGTCGTCGGCAAGAATCTCGCGGTGACGCCGGGCGCGGTCGTCTACGAGAACGATCTGATCCAGTTGATCCAG
TACACGCCCACGACAGCCACCGTCTTCGAGCGGCCGCTGCTCATCGTGCCGCCGTGCATCAACAAGTTCTACATCCTCGA
TCTGCAGCCGGAGAATTCGCTCGTCGCGCACGCGCTGTCGTGCGGCCATCAGGTGTTCCTCGTGTCGTGGCGCAATGCCG
ACGCGTCGGTCGCGCACAAGACGTGGGACGACTACATCGACGAGGGCCTGCTCGCCGCGATCGACGTCGTCCAGCAGGTG
AGCGGGCGCGAGCAGATCAACACGCTCGGCTTCTGCGTCGGCGGCACGATGCTTGCGACGGCGCTCGCGGTGCTCGCCGC
GCGCGGCGAGCACCCGGCCGCGTCGATGACGCTGCTCACCTCGATGCTCGACTTCTCCGACACGGGCATTCTCGACGTGT
TCGTCGACGAGGCGCACGTGCAGATGCGCGAGCAGACCATCGGCGGCAAGGGCGGCGCGCCCGCGGGCTTGATGCGCGGC
GTCGAGTTCGCGAACACGTTTTCGTTTCTGCGTCCGAACGATCTCGTGTGGAACTATGTCGTCGACAACTACCTGAAGGG
CCGCACGCCCGCGCCGTTCGATCTGCTGTACTGGAACGGCGATTCGACGAGCCTGCCCGGCCCGATGTACGCGTGGTATC
TGCGGAATACCTATCTCGAAAACAAGCTGCGCGAGCCGGATGCGCTCACGGTGTGCGGCGAGCCCGTCGATCTGTCGCGC
ATCGACGTGCCTACGTTCATCTACGGCTCGCGCGAGGATCACATCGTGCCGTGGCAGACCGCGTACGCGTCGACGTCGCT
GCTGACGGGGCCGCTGAAGTTCGTGCTGGGCGCGTCGGGCCACATCGCAGGCGTGATCAATCCGCCCGCGAAGCGCAAGC
GCAGCTACTGGAGCTACGACGCGAGCGCGAAGGAGCTGCCGGAATCGGCGAACGACTGGCTCGATGCGGCCGTCGAACAC
CCTGGCAGTTGGTGGCCGGTATGGATCGAGTGGCTCGATCAGTACGGCGGCAAGAAGGTGAAGCCGCGCGCGCACCTCGG
CTGCGCGCGCTTCCCGGTGATCGAGCCCGCGCCCGGCCGATATGTGTTGCAACGCGATTGA

Upstream 100 bases:

>100_bases
CACCGTTAAGGCAGGTATGACAGCATCGAAAAAATCGTCGACGTCCTCTCACACGGATACTCCCCAGGGTCGCAGCACAG
CCGGATTGGCGGCCCAGCCC

Downstream 100 bases:

>100_bases
CGAACGGCGCAAGGCGGAGCACGCTTTGCGTCGCGACCGATTTTTAACAGGGCGGTTCGCGGCGCGCCGTGCCGCGCGCG
CCCGGAGGATAGTGAAATGA

Product: poly-beta-hydroxybutyrate polymerase

Products: NA

Alternate protein names: PHA synthase; PHB synthase; Poly(3-hydroxyalkanoate) polymerase; PHA polymerase; Poly(3-hydroxybutyrate) polymerase; PHB polymerase; Polyhydroxyalkanoic acid synthase [H]

Number of amino acids: Translated: 606; Mature: 606

Protein sequence:

>606_residues
MQQLFESWLGAWRSFADPARAAAGDAPSPSPSPSPFAAFQPPQPFAFAMPAMPPMPPMPDWSGAAASFAGLAPVASVPPA
RLQKLQADYSRDCLALIQQASAATPTVPELKDRRFSADAWKASPAHGFAAAWYLLNARYLQELADALETDPKTRERIRFT
VQQWTAAASPSNFLALNPEAQKNLVETQGESLRLGMMNLLADMQRGKISQTDESQFVVGKNLAVTPGAVVYENDLIQLIQ
YTPTTATVFERPLLIVPPCINKFYILDLQPENSLVAHALSCGHQVFLVSWRNADASVAHKTWDDYIDEGLLAAIDVVQQV
SGREQINTLGFCVGGTMLATALAVLAARGEHPAASMTLLTSMLDFSDTGILDVFVDEAHVQMREQTIGGKGGAPAGLMRG
VEFANTFSFLRPNDLVWNYVVDNYLKGRTPAPFDLLYWNGDSTSLPGPMYAWYLRNTYLENKLREPDALTVCGEPVDLSR
IDVPTFIYGSREDHIVPWQTAYASTSLLTGPLKFVLGASGHIAGVINPPAKRKRSYWSYDASAKELPESANDWLDAAVEH
PGSWWPVWIEWLDQYGGKKVKPRAHLGCARFPVIEPAPGRYVLQRD

Sequences:

>Translated_606_residues
MQQLFESWLGAWRSFADPARAAAGDAPSPSPSPSPFAAFQPPQPFAFAMPAMPPMPPMPDWSGAAASFAGLAPVASVPPA
RLQKLQADYSRDCLALIQQASAATPTVPELKDRRFSADAWKASPAHGFAAAWYLLNARYLQELADALETDPKTRERIRFT
VQQWTAAASPSNFLALNPEAQKNLVETQGESLRLGMMNLLADMQRGKISQTDESQFVVGKNLAVTPGAVVYENDLIQLIQ
YTPTTATVFERPLLIVPPCINKFYILDLQPENSLVAHALSCGHQVFLVSWRNADASVAHKTWDDYIDEGLLAAIDVVQQV
SGREQINTLGFCVGGTMLATALAVLAARGEHPAASMTLLTSMLDFSDTGILDVFVDEAHVQMREQTIGGKGGAPAGLMRG
VEFANTFSFLRPNDLVWNYVVDNYLKGRTPAPFDLLYWNGDSTSLPGPMYAWYLRNTYLENKLREPDALTVCGEPVDLSR
IDVPTFIYGSREDHIVPWQTAYASTSLLTGPLKFVLGASGHIAGVINPPAKRKRSYWSYDASAKELPESANDWLDAAVEH
PGSWWPVWIEWLDQYGGKKVKPRAHLGCARFPVIEPAPGRYVLQRD
>Mature_606_residues
MQQLFESWLGAWRSFADPARAAAGDAPSPSPSPSPFAAFQPPQPFAFAMPAMPPMPPMPDWSGAAASFAGLAPVASVPPA
RLQKLQADYSRDCLALIQQASAATPTVPELKDRRFSADAWKASPAHGFAAAWYLLNARYLQELADALETDPKTRERIRFT
VQQWTAAASPSNFLALNPEAQKNLVETQGESLRLGMMNLLADMQRGKISQTDESQFVVGKNLAVTPGAVVYENDLIQLIQ
YTPTTATVFERPLLIVPPCINKFYILDLQPENSLVAHALSCGHQVFLVSWRNADASVAHKTWDDYIDEGLLAAIDVVQQV
SGREQINTLGFCVGGTMLATALAVLAARGEHPAASMTLLTSMLDFSDTGILDVFVDEAHVQMREQTIGGKGGAPAGLMRG
VEFANTFSFLRPNDLVWNYVVDNYLKGRTPAPFDLLYWNGDSTSLPGPMYAWYLRNTYLENKLREPDALTVCGEPVDLSR
IDVPTFIYGSREDHIVPWQTAYASTSLLTGPLKFVLGASGHIAGVINPPAKRKRSYWSYDASAKELPESANDWLDAAVEH
PGSWWPVWIEWLDQYGGKKVKPRAHLGCARFPVIEPAPGRYVLQRD

Specific function: Polymerizes d(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation [H]

COG id: COG3243

COG function: function code I; Poly(3-hydroxyalkanoate) synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHA/PHB synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010963
- InterPro:   IPR010941 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF07167 PhaC_N [H]

EC number: NA

Molecular weight: Translated: 66537; Mature: 66537

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQLFESWLGAWRSFADPARAAAGDAPSPSPSPSPFAAFQPPQPFAFAMPAMPPMPPMPD
CHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCC
WSGAAASFAGLAPVASVPPARLQKLQADYSRDCLALIQQASAATPTVPELKDRRFSADAW
CCCCHHHHHCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCHHHCCCCCCCCC
KASPAHGFAAAWYLLNARYLQELADALETDPKTRERIRFTVQQWTAAASPSNFLALNPEA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECCHH
QKNLVETQGESLRLGMMNLLADMQRGKISQTDESQFVVGKNLAVTPGAVVYENDLIQLIQ
HHHHHHHCCCCEEHHHHHHHHHHHCCCCCCCCCCCEEECCCEEECCCCEEEHHHHHHHHH
YTPTTATVFERPLLIVPPCINKFYILDLQPENSLVAHALSCGHQVFLVSWRNADASVAHK
CCCCHHHHHCCCCEEECCCCCCEEEEEECCCCHHHHHHHHCCCEEEEEEECCCCCHHHHH
TWDDYIDEGLLAAIDVVQQVSGREQINTLGFCVGGTMLATALAVLAARGEHPAASMTLLT
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
SMLDFSDTGILDVFVDEAHVQMREQTIGGKGGAPAGLMRGVEFANTFSFLRPNDLVWNYV
HHHCCCCCCEEEEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHH
VDNYLKGRTPAPFDLLYWNGDSTSLPGPMYAWYLRNTYLENKLREPDALTVCGEPVDLSR
HHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCC
IDVPTFIYGSREDHIVPWQTAYASTSLLTGPLKFVLGASGHIAGVINPPAKRKRSYWSYD
CCCCEEEECCCCCCCCCCHHHHHCHHHHHHHHHHHHCCCCCEEEEECCCHHHHCCCCCCC
ASAKELPESANDWLDAAVEHPGSWWPVWIEWLDQYGGKKVKPRAHLGCARFPVIEPAPGR
CCHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCC
YVLQRD
EEEECC
>Mature Secondary Structure
MQQLFESWLGAWRSFADPARAAAGDAPSPSPSPSPFAAFQPPQPFAFAMPAMPPMPPMPD
CHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCC
WSGAAASFAGLAPVASVPPARLQKLQADYSRDCLALIQQASAATPTVPELKDRRFSADAW
CCCCHHHHHCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCHHHCCCCCCCCC
KASPAHGFAAAWYLLNARYLQELADALETDPKTRERIRFTVQQWTAAASPSNFLALNPEA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECCHH
QKNLVETQGESLRLGMMNLLADMQRGKISQTDESQFVVGKNLAVTPGAVVYENDLIQLIQ
HHHHHHHCCCCEEHHHHHHHHHHHCCCCCCCCCCCEEECCCEEECCCCEEEHHHHHHHHH
YTPTTATVFERPLLIVPPCINKFYILDLQPENSLVAHALSCGHQVFLVSWRNADASVAHK
CCCCHHHHHCCCCEEECCCCCCEEEEEECCCCHHHHHHHHCCCEEEEEEECCCCCHHHHH
TWDDYIDEGLLAAIDVVQQVSGREQINTLGFCVGGTMLATALAVLAARGEHPAASMTLLT
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
SMLDFSDTGILDVFVDEAHVQMREQTIGGKGGAPAGLMRGVEFANTFSFLRPNDLVWNYV
HHHCCCCCCEEEEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHH
VDNYLKGRTPAPFDLLYWNGDSTSLPGPMYAWYLRNTYLENKLREPDALTVCGEPVDLSR
HHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCC
IDVPTFIYGSREDHIVPWQTAYASTSLLTGPLKFVLGASGHIAGVINPPAKRKRSYWSYD
CCCCEEEECCCCCCCCCCHHHHHCHHHHHHHHHHHHCCCCCEEEEECCCHHHHCCCCCCC
ASAKELPESANDWLDAAVEHPGSWWPVWIEWLDQYGGKKVKPRAHLGCARFPVIEPAPGR
CCHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCC
YVLQRD
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2670936; 1987116 [H]