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The map label for this gene is dhaK [H]

Identifier: 237812430

GI number: 237812430

Start: 2147505

End: 2149217

Strand: Reverse

Name: dhaK [H]

Synonym: GBP346_A2178

Alternate gene names: 237812430

Gene position: 2149217-2147505 (Counterclockwise)

Preceding gene: 237812431

Following gene: 237812425

Centisome position: 52.44

GC content: 75.07

Gene sequence:

>1713_bases
ATGAAAAAGCTCGTCAACCATCCGTCCGACGTCGTGCGCGAAATGCTGGAAGGCATCGCGCGGCAATCGCCGCATGTCGC
CATGCTCGGCGACGAACACGTGCTGATCCGGCGCCCGCTGCCGGAGCCGGCCAAGCGCGCGGTCGCGGTCATCTCCGGCG
GCGGCAGCGGCCACGAGCCGGCGCATGGCGGCTATGTCGGCGCGGGAATGCTGAGCGCGGCCGTGTGCGGCGAAGTCTTC
ACGTCGCCGTCCGCCGACGCGGTGCTCGCCGCGATTCGCGCGACGGCGGGCCCGCACGGCGCGTTGCTCATCGTGAAGAA
CTACACGGGCGACCGCCTCAATTTCGGTCTCGCGGCCGAGCTCGCGCGCGCGGAGGGCATTCCGGTCGAGATCGTTGTCG
TCGCGGACGACGTGTCGCTGCGCGCGCTCACCGAGCGCGGGCGCCGCCGCGGCATCGCCGGCACCGTGCTCGTGCACAAG
CTCGCCGGCGCGGCCGCCGAGCGCGGCCTCACGCTGGCGCAGGTGGCCGCCGCCGCGAACACGGCGGCGGCGCGGCTCGG
CACGATGGGCGTCGCGCTCGACGGCTGCACGATGCCGGGCGCCGAGCAATCCGGCTTTCGCCTGGCCGATCACGAAATCG
AGCTTGGACTGGGCATACACGGCGAAAAGGGCGTGCAGCGCACGGCGCCGATGCCGGCCGACGCGCTGGCCGAAACGCTC
GTCGCGGCGATCGTCGACGATCAGTCGATCGCGCGCGGCGATCGGGTCGCGCTGCTCGTGAACGGGCTCGGCGCGACGCC
CGACATGGAGCTCGGCATCGTGCTGCGCGCGGCGTACGACAGCCTGAGCCGGCGCGGCGTCGAGGTGGCGCGTGCATGGG
CGGGCACCTTCCTGTCCGCGCTCGACATGCCGGGCTGCTCGATTTCGCTGCTCAAGCTGAACGACGACATGCTCGAGCTG
CTCGACGCGCCGACGCAGGCGCGCGCGTGGCCCGGCGGCGGCGCGGTGAACCGGGACATTCGCGTGGCGTGCGCCGAAGC
CGGCCCGGCCGACGGCCCGCCGCAATGGGCGACGGCGAGCATGGCGAGCGCGATGGGCGCCGACGTGCTGCAACCCGCGC
TGCATGCGGTCGCCGCCGCGCTGATCGACCACGAGCCGGTGTTGACCGAACTCGATGCCGTCGCGGGCGACGGCGATCTG
GGCGCGAGCATGCGGCGCGCGGCGAACGCGATGCTTGCGCTGCCCGCCGACGCGTATCGGGGGCCGGCCGTCCTGCTCGC
CGCGCTCGGCGCCGCGCTGCGCCGGGCGATCGCGGGCAGCTCCGGGCCGTTCTACGCGACGGCGCTGGTGCGTGCGGCCC
GCCGGCTCGCCGAGGTGCCGGATCCCGGCGCGCGCGACTGGGCGAGCGCGTTTCGCGGCGGCGTCGACGCGATCGGCGAA
CTGGGCGGCGCGAAGCCCGGCGATCGCACGATGCTCGACGCATTGGTGCCCGCCGCCGATGCGTTCGAGCGCGAACTGTC
GGCGGGCGGCAGCGCGCGTGCCGCATGGGCGGCGGCCGTGCGCGCGGCCGACGAAGGCGCGGCGCGCACCGCGGGCATGA
CGCCGCGCGCGGGGCGCGCGAGCTATCTGGGCGCGCGCGCGGTGGGCGCGCCCGACGGCGGTGCGGTCGCCGTCGCGTGC
TGGCTGCGCGCGTTGCAGCCGCACGTGGCGTAG

Upstream 100 bases:

>100_bases
GCGGGCTCGCCCACGAACGGCCGCTTCGCGCGCGTTCAGCCGCATGCGCCCGATGCCGCGACGGCGCGCCGCCCTCACTC
ACCGCCAGGAAACCGCCGCC

Downstream 100 bases:

>100_bases
CGGCGCATCGCGCGCTTCGGTGGCGGGCATCGCGGCCGGCGTCGCCGTTCGGGGCCGGCCGGCGATCCGCCGGCCGTCGG
CGTGGCGCGCGCGGGCGGGG

Product: dihydroxyacetone kinase

Products: NA

Alternate protein names: DHA kinase; Glycerone kinase [H]

Number of amino acids: Translated: 570; Mature: 570

Protein sequence:

>570_residues
MKKLVNHPSDVVREMLEGIARQSPHVAMLGDEHVLIRRPLPEPAKRAVAVISGGGSGHEPAHGGYVGAGMLSAAVCGEVF
TSPSADAVLAAIRATAGPHGALLIVKNYTGDRLNFGLAAELARAEGIPVEIVVVADDVSLRALTERGRRRGIAGTVLVHK
LAGAAAERGLTLAQVAAAANTAAARLGTMGVALDGCTMPGAEQSGFRLADHEIELGLGIHGEKGVQRTAPMPADALAETL
VAAIVDDQSIARGDRVALLVNGLGATPDMELGIVLRAAYDSLSRRGVEVARAWAGTFLSALDMPGCSISLLKLNDDMLEL
LDAPTQARAWPGGGAVNRDIRVACAEAGPADGPPQWATASMASAMGADVLQPALHAVAAALIDHEPVLTELDAVAGDGDL
GASMRRAANAMLALPADAYRGPAVLLAALGAALRRAIAGSSGPFYATALVRAARRLAEVPDPGARDWASAFRGGVDAIGE
LGGAKPGDRTMLDALVPAADAFERELSAGGSARAAWAAAVRAADEGAARTAGMTPRAGRASYLGARAVGAPDGGAVAVAC
WLRALQPHVA

Sequences:

>Translated_570_residues
MKKLVNHPSDVVREMLEGIARQSPHVAMLGDEHVLIRRPLPEPAKRAVAVISGGGSGHEPAHGGYVGAGMLSAAVCGEVF
TSPSADAVLAAIRATAGPHGALLIVKNYTGDRLNFGLAAELARAEGIPVEIVVVADDVSLRALTERGRRRGIAGTVLVHK
LAGAAAERGLTLAQVAAAANTAAARLGTMGVALDGCTMPGAEQSGFRLADHEIELGLGIHGEKGVQRTAPMPADALAETL
VAAIVDDQSIARGDRVALLVNGLGATPDMELGIVLRAAYDSLSRRGVEVARAWAGTFLSALDMPGCSISLLKLNDDMLEL
LDAPTQARAWPGGGAVNRDIRVACAEAGPADGPPQWATASMASAMGADVLQPALHAVAAALIDHEPVLTELDAVAGDGDL
GASMRRAANAMLALPADAYRGPAVLLAALGAALRRAIAGSSGPFYATALVRAARRLAEVPDPGARDWASAFRGGVDAIGE
LGGAKPGDRTMLDALVPAADAFERELSAGGSARAAWAAAVRAADEGAARTAGMTPRAGRASYLGARAVGAPDGGAVAVAC
WLRALQPHVA
>Mature_570_residues
MKKLVNHPSDVVREMLEGIARQSPHVAMLGDEHVLIRRPLPEPAKRAVAVISGGGSGHEPAHGGYVGAGMLSAAVCGEVF
TSPSADAVLAAIRATAGPHGALLIVKNYTGDRLNFGLAAELARAEGIPVEIVVVADDVSLRALTERGRRRGIAGTVLVHK
LAGAAAERGLTLAQVAAAANTAAARLGTMGVALDGCTMPGAEQSGFRLADHEIELGLGIHGEKGVQRTAPMPADALAETL
VAAIVDDQSIARGDRVALLVNGLGATPDMELGIVLRAAYDSLSRRGVEVARAWAGTFLSALDMPGCSISLLKLNDDMLEL
LDAPTQARAWPGGGAVNRDIRVACAEAGPADGPPQWATASMASAMGADVLQPALHAVAAALIDHEPVLTELDAVAGDGDL
GASMRRAANAMLALPADAYRGPAVLLAALGAALRRAIAGSSGPFYATALVRAARRLAEVPDPGARDWASAFRGGVDAIGE
LGGAKPGDRTMLDALVPAADAFERELSAGGSARAAWAAAVRAADEGAARTAGMTPRAGRASYLGARAVGAPDGGAVAVAC
WLRALQPHVA

Specific function: Catalyzes the phosphorylation of dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaL domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=567, Percent_Identity=43.0335097001764, Blast_Score=367, Evalue=1e-101,
Organism=Escherichia coli, GI87081857, Length=356, Percent_Identity=41.0112359550562, Blast_Score=241, Evalue=7e-65,
Organism=Escherichia coli, GI1787449, Length=179, Percent_Identity=34.6368715083799, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17565018, Length=577, Percent_Identity=35.0086655112652, Blast_Score=312, Evalue=3e-85,
Organism=Saccharomyces cerevisiae, GI6321055, Length=598, Percent_Identity=34.6153846153846, Blast_Score=268, Evalue=2e-72,
Organism=Saccharomyces cerevisiae, GI6323570, Length=597, Percent_Identity=33.1658291457286, Blast_Score=266, Evalue=7e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR004007
- InterPro:   IPR012734 [H]

Pfam domain/function: PF02733 Dak1; PF02734 Dak2 [H]

EC number: =2.7.1.29 [H]

Molecular weight: Translated: 57843; Mature: 57843

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLVNHPSDVVREMLEGIARQSPHVAMLGDEHVLIRRPLPEPAKRAVAVISGGGSGHEP
CCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCHHHHEEEEEECCCCCCCC
AHGGYVGAGMLSAAVCGEVFTSPSADAVLAAIRATAGPHGALLIVKNYTGDRLNFGLAAE
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHH
LARAEGIPVEIVVVADDVSLRALTERGRRRGIAGTVLVHKLAGAAAERGLTLAQVAAAAN
HHHCCCCCEEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHH
TAAARLGTMGVALDGCTMPGAEQSGFRLADHEIELGLGIHGEKGVQRTAPMPADALAETL
HHHHHHHHCCEEECCCCCCCCCCCCCEEECCEEEEEECCCCCCCCCCCCCCCHHHHHHHH
VAAIVDDQSIARGDRVALLVNGLGATPDMELGIVLRAAYDSLSRRGVEVARAWAGTFLSA
HHHHHCCHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDMPGCSISLLKLNDDMLELLDAPTQARAWPGGGAVNRDIRVACAEAGPADGPPQWATAS
HCCCCCEEEEEECCHHHHHHHCCCCHHCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHH
MASAMGADVLQPALHAVAAALIDHEPVLTELDAVAGDGDLGASMRRAANAMLALPADAYR
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHEEECCCHHCC
GPAVLLAALGAALRRAIAGSSGPFYATALVRAARRLAEVPDPGARDWASAFRGGVDAIGE
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHH
LGGAKPGDRTMLDALVPAADAFERELSAGGSARAAWAAAVRAADEGAARTAGMTPRAGRA
HCCCCCCCHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHCCCCCCCCCCH
SYLGARAVGAPDGGAVAVACWLRALQPHVA
HHCCCCCCCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKLVNHPSDVVREMLEGIARQSPHVAMLGDEHVLIRRPLPEPAKRAVAVISGGGSGHEP
CCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCHHHHEEEEEECCCCCCCC
AHGGYVGAGMLSAAVCGEVFTSPSADAVLAAIRATAGPHGALLIVKNYTGDRLNFGLAAE
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHH
LARAEGIPVEIVVVADDVSLRALTERGRRRGIAGTVLVHKLAGAAAERGLTLAQVAAAAN
HHHCCCCCEEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHH
TAAARLGTMGVALDGCTMPGAEQSGFRLADHEIELGLGIHGEKGVQRTAPMPADALAETL
HHHHHHHHCCEEECCCCCCCCCCCCCEEECCEEEEEECCCCCCCCCCCCCCCHHHHHHHH
VAAIVDDQSIARGDRVALLVNGLGATPDMELGIVLRAAYDSLSRRGVEVARAWAGTFLSA
HHHHHCCHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDMPGCSISLLKLNDDMLELLDAPTQARAWPGGGAVNRDIRVACAEAGPADGPPQWATAS
HCCCCCEEEEEECCHHHHHHHCCCCHHCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHH
MASAMGADVLQPALHAVAAALIDHEPVLTELDAVAGDGDLGASMRRAANAMLALPADAYR
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHEEECCCHHCC
GPAVLLAALGAALRRAIAGSSGPFYATALVRAARRLAEVPDPGARDWASAFRGGVDAIGE
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHH
LGGAKPGDRTMLDALVPAADAFERELSAGGSARAAWAAAVRAADEGAARTAGMTPRAGRA
HCCCCCCCHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHCCCCCCCCCCH
SYLGARAVGAPDGGAVAVACWLRALQPHVA
HHCCCCCCCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA