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The map label for this gene is yiaY [H]

Identifier: 237812420

GI number: 237812420

Start: 2139402

End: 2140079

Strand: Reverse

Name: yiaY [H]

Synonym: GBP346_A2168

Alternate gene names: 237812420

Gene position: 2140079-2139402 (Counterclockwise)

Preceding gene: 237812421

Following gene: 237812419

Centisome position: 52.22

GC content: 68.44

Gene sequence:

>678_bases
GTGAAGATGGCGATCGTCGACTGGCGTTGCACGCCGCTCATCGCGATCGACGACCCGAGCCTGATGGTGGCGATGCCGCC
CGCGCTGACGGCCGCAACCGGCATGGACGCGCTCACGCACGCGGTGGAGGCCTACGTTTCCACCGCCGCGACGCCGATCA
CCGACGCCTGCGCCGAAAAGGCGATCGCGTTGATCGGCGAATGGCTGCCGAAGGCCGTCGCGAACGGCGAATCGATGCAG
GCGCGCGCGGCGATGTGCTACGCGCAGTACCTCGCCGGGATGGCGTTCAACAATGCGTCGCTCGGCTATGTGCACGCGAT
GGCGCACCAGCTCGGCGGGTTCTACAACCTTCCGCACGGGGTCTGCAACGCGATCCTGCTGCCGCACGTGTGCGAGTTCA
ACCTGATCGCCGCGCCCGAGCGTTTCGCCGCCATCGCGCCGCTGCTCGGCGTCAGGACGGCGGGCATGAGCACCCCCGAT
GCCGCACGCGCCGCCATTGCGGCGATCCGCGCGCTCTCGGCGTCGATCGGCATCCCGTCGGGCTTGGCCGCGCTCGGCGT
GAAGGCTGAAGACCATGAGGTGATGGCCGGCAACGCGCAGAAAGATGCGTGTATGCTGACCAATCCGCGCAAGGCGACGC
TCGCGCAGGTCATCGCGATCTTCGCGGCGGCGATGTGA

Upstream 100 bases:

>100_bases
AATCGACGGTGCCGATGACGCCGTTGATTTCGATCAACACGACGGCGGGCACGGCGGCGGAGATGACGCGCTTTTGCATC
ATCACGAATTCCAGCATCAC

Downstream 100 bases:

>100_bases
GCGCCGCGGCCGCCATGCCGCGCGTGCGCGGATAGCGCATTGAACGCACATCGAGCGCGTATCGGGCAAGGGCGCGCGCG
TCGTTGGAAGCCCGTCATCG

Product: alcohol dehydrogenase, iron-containing

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKMAIVDWRCTPLIAIDDPSLMVAMPPALTAATGMDALTHAVEAYVSTAATPITDACAEKAIALIGEWLPKAVANGESMQ
ARAAMCYAQYLAGMAFNNASLGYVHAMAHQLGGFYNLPHGVCNAILLPHVCEFNLIAAPERFAAIAPLLGVRTAGMSTPD
AARAAIAAIRALSASIGIPSGLAALGVKAEDHEVMAGNAQKDACMLTNPRKATLAQVIAIFAAAM

Sequences:

>Translated_225_residues
MKMAIVDWRCTPLIAIDDPSLMVAMPPALTAATGMDALTHAVEAYVSTAATPITDACAEKAIALIGEWLPKAVANGESMQ
ARAAMCYAQYLAGMAFNNASLGYVHAMAHQLGGFYNLPHGVCNAILLPHVCEFNLIAAPERFAAIAPLLGVRTAGMSTPD
AARAAIAAIRALSASIGIPSGLAALGVKAEDHEVMAGNAQKDACMLTNPRKATLAQVIAIFAAAM
>Mature_225_residues
MKMAIVDWRCTPLIAIDDPSLMVAMPPALTAATGMDALTHAVEAYVSTAATPITDACAEKAIALIGEWLPKAVANGESMQ
ARAAMCYAQYLAGMAFNNASLGYVHAMAHQLGGFYNLPHGVCNAILLPHVCEFNLIAAPERFAAIAPLLGVRTAGMSTPD
AARAAIAAIRALSASIGIPSGLAALGVKAEDHEVMAGNAQKDACMLTNPRKATLAQVIAIFAAAM

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=258, Percent_Identity=25.968992248062, Blast_Score=89, Evalue=4e-18,
Organism=Escherichia coli, GI48994951, Length=225, Percent_Identity=62.2222222222222, Blast_Score=279, Evalue=1e-76,
Organism=Escherichia coli, GI1789163, Length=223, Percent_Identity=45.7399103139013, Blast_Score=187, Evalue=5e-49,
Organism=Escherichia coli, GI87082107, Length=213, Percent_Identity=44.6009389671362, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1787493, Length=241, Percent_Identity=34.0248962655602, Blast_Score=130, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17537053, Length=229, Percent_Identity=22.707423580786, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321181, Length=226, Percent_Identity=57.0796460176991, Blast_Score=254, Evalue=1e-68,
Organism=Drosophila melanogaster, GI24657991, Length=257, Percent_Identity=24.5136186770428, Blast_Score=84, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 23246; Mature: 23246

Theoretical pI: Translated: 6.49; Mature: 6.49

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
8.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
8.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMAIVDWRCTPLIAIDDPSLMVAMPPALTAATGMDALTHAVEAYVSTAATPITDACAEK
CCEEEEECCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AIALIGEWLPKAVANGESMQARAAMCYAQYLAGMAFNNASLGYVHAMAHQLGGFYNLPHG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHH
VCNAILLPHVCEFNLIAAPERFAAIAPLLGVRTAGMSTPDAARAAIAAIRALSASIGIPS
HHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC
GLAALGVKAEDHEVMAGNAQKDACMLTNPRKATLAQVIAIFAAAM
CHHHHCCCCCCCEEEECCCCCCEEEECCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKMAIVDWRCTPLIAIDDPSLMVAMPPALTAATGMDALTHAVEAYVSTAATPITDACAEK
CCEEEEECCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AIALIGEWLPKAVANGESMQARAAMCYAQYLAGMAFNNASLGYVHAMAHQLGGFYNLPHG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHH
VCNAILLPHVCEFNLIAAPERFAAIAPLLGVRTAGMSTPDAARAAIAAIRALSASIGIPS
HHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC
GLAALGVKAEDHEVMAGNAQKDACMLTNPRKATLAQVIAIFAAAM
CHHHHCCCCCCCEEEECCCCCCEEEECCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]