Click here to switch to the map view.

The map label for this gene is livK [C]

Identifier: 237812253

GI number: 237812253

Start: 1954424

End: 1955641

Strand: Reverse

Name: livK [C]

Synonym: GBP346_A2001

Alternate gene names: 237812253

Gene position: 1955641-1954424 (Counterclockwise)

Preceding gene: 237812254

Following gene: 237812251

Centisome position: 47.72

GC content: 68.8

Gene sequence:

>1218_bases
GTGTCGATCCATGCCGAAAGCGATTGGGCATCCGAACCGATCGATTCGTTTGAGGCCGCCCGGCAATCGAAAATCGTGAC
GTTTTCTCGAGCGAGGGTCGACATGAACGTTCGCATGGGGTGTTTATCGCTGCTGGCCGCCGTCGCATTCGACGCGCACG
CGCAATCATCGGTCGTCCGGATCGGCGTCGCGATGCCGCTGACGGGGCCCGTCGCCCATCTGGGCAAGGACGTGCAGAAC
GGCGCGCAGCTCGCCGTCGACGAGCTGAACCGCGCGCCGCCGACAATCGAAGGCAAGCCGGTGAAGTTCGTGCTCGTCGT
CGAAGACGATCAGGGCGATCCACGGCAGGCGGTGCAGGTCGCGCAGCGCCTCGTCGACGCGCGGGTCGCGGGCGTCGTCG
GCGATCTGAACTCGGGGCCGACGATCGTCGCGGCGAAGGTCTACGCGGCGGCCGGCATCGCGCAGATCGCGCCCGCCGCG
ACCCATCCCGCGTACACGCAGCTAGGCTACAAGACCGCGTTCCGGCTGATGGCGACCGACAACCAGCAAGGCGCGTCGCT
CGCCGGGCTCGCCGCGAAGCTCGCGAAAGGCCGGCCGATCGCGCTGATCGACGATCGCGGCGCCTACGGCCAGGGCCTCA
TCGATCAGACGGAGAAGACACTGCGCGCGAGCGGCGTCACGCGAATCATCCGCGACTACACGACGGACACCGCGGTCAAT
TTCGCGTCGATTCTCACGCGCGTGAAGGGCGCGCATGCGGCCGTGATCGTCTACGGCGGCGCCGATGCACAGGCGGGGCC
GATGGTGCGGCAGATGAAGGCGCTCGGAATCGACGCGGCGTTCGTCGGCAGCGACGGCGTGTGCACCGGGCAGTGGACGG
CGCTGTCGTCGGGCGCGAACGAAGGCCAGTTCTGCACGCAAGCGGGCGACCCGCGCGCGAGGATGGCGGGTTACGCGGCG
TTCGAGCGGCGTTTCGAGGCGCGCTACGGCAAGGTGATCGTGTTCGCGCCGTATGGCTACGACGCGGTGATGCTGCTCGC
CGACGCGATGCGGCGCGCGAATTCGACCGAGCCGGCCGCTTTGCTCGGCGCGCTCGCGACGACCCGTTACGACGGCGTGA
TCGGCCGCATCCGCTTCAGTCCGCAGGGCGACAACCTGAACGGCGCGGTGACGGTCTACCGCGTGCAGCGCGGCGCGCTC
GTGCCGGTGTCCGACTGA

Upstream 100 bases:

>100_bases
CATTCCGAGGGCCTGGCTTCGTGCGCGACGTCGCCGCACCGCGCACGGCGTATCACGAGAACCCGAACGCGCGGCGAGTT
TCCCGACGGGCGCGCCCACT

Downstream 100 bases:

>100_bases
CACGCGATGCGGCGGCCGCGGAAGGCGCGCGCGCCGCTTTGTCGAAGGCGCCGTTCGCGGCTCGGCAAGACCGGTTTGCC
GGACGCGCGCCCGTTCGCCG

Product: extracellular ligand-binding receptor

Products: ADP; phosphate; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MSIHAESDWASEPIDSFEAARQSKIVTFSRARVDMNVRMGCLSLLAAVAFDAHAQSSVVRIGVAMPLTGPVAHLGKDVQN
GAQLAVDELNRAPPTIEGKPVKFVLVVEDDQGDPRQAVQVAQRLVDARVAGVVGDLNSGPTIVAAKVYAAAGIAQIAPAA
THPAYTQLGYKTAFRLMATDNQQGASLAGLAAKLAKGRPIALIDDRGAYGQGLIDQTEKTLRASGVTRIIRDYTTDTAVN
FASILTRVKGAHAAVIVYGGADAQAGPMVRQMKALGIDAAFVGSDGVCTGQWTALSSGANEGQFCTQAGDPRARMAGYAA
FERRFEARYGKVIVFAPYGYDAVMLLADAMRRANSTEPAALLGALATTRYDGVIGRIRFSPQGDNLNGAVTVYRVQRGAL
VPVSD

Sequences:

>Translated_405_residues
MSIHAESDWASEPIDSFEAARQSKIVTFSRARVDMNVRMGCLSLLAAVAFDAHAQSSVVRIGVAMPLTGPVAHLGKDVQN
GAQLAVDELNRAPPTIEGKPVKFVLVVEDDQGDPRQAVQVAQRLVDARVAGVVGDLNSGPTIVAAKVYAAAGIAQIAPAA
THPAYTQLGYKTAFRLMATDNQQGASLAGLAAKLAKGRPIALIDDRGAYGQGLIDQTEKTLRASGVTRIIRDYTTDTAVN
FASILTRVKGAHAAVIVYGGADAQAGPMVRQMKALGIDAAFVGSDGVCTGQWTALSSGANEGQFCTQAGDPRARMAGYAA
FERRFEARYGKVIVFAPYGYDAVMLLADAMRRANSTEPAALLGALATTRYDGVIGRIRFSPQGDNLNGAVTVYRVQRGAL
VPVSD
>Mature_404_residues
SIHAESDWASEPIDSFEAARQSKIVTFSRARVDMNVRMGCLSLLAAVAFDAHAQSSVVRIGVAMPLTGPVAHLGKDVQNG
AQLAVDELNRAPPTIEGKPVKFVLVVEDDQGDPRQAVQVAQRLVDARVAGVVGDLNSGPTIVAAKVYAAAGIAQIAPAAT
HPAYTQLGYKTAFRLMATDNQQGASLAGLAAKLAKGRPIALIDDRGAYGQGLIDQTEKTLRASGVTRIIRDYTTDTAVNF
ASILTRVKGAHAAVIVYGGADAQAGPMVRQMKALGIDAAFVGSDGVCTGQWTALSSGANEGQFCTQAGDPRARMAGYAAF
ERRFEARYGKVIVFAPYGYDAVMLLADAMRRANSTEPAALLGALATTRYDGVIGRIRFSPQGDNLNGAVTVYRVQRGALV
PVSD

Specific function: Component of an amino-acid transport system (Potential) [H]

COG id: COG0683

COG function: function code E; ABC-type branched-chain amino acid transport systems, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the leucine-binding protein family [H]

Homologues:

Organism=Escherichia coli, GI1789867, Length=344, Percent_Identity=31.6860465116279, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI48994941, Length=355, Percent_Identity=28.169014084507, Blast_Score=131, Evalue=1e-31,

Paralogues:

None

Copy number: 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001828
- InterPro:   IPR000709 [H]

Pfam domain/function: PF01094 ANF_receptor [H]

EC number: NA

Molecular weight: Translated: 42578; Mature: 42447

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIHAESDWASEPIDSFEAARQSKIVTFSRARVDMNVRMGCLSLLAAVAFDAHAQSSVVR
CCCCCCCCCCCCCHHHHHHHHHCCEEEEEEEEEECHHHHHHHHHHHHHHHCCCCCCCEEE
IGVAMPLTGPVAHLGKDVQNGAQLAVDELNRAPPTIEGKPVKFVLVVEDDQGDPRQAVQV
EEEECCCCCHHHHHCHHHHCCHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCHHHHHHH
AQRLVDARVAGVVGDLNSGPTIVAAKVYAAAGIAQIAPAATHPAYTQLGYKTAFRLMATD
HHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHCHHHHCCCCCCCHHHHHHHHHEEEEEECC
NQQGASLAGLAAKLAKGRPIALIDDRGAYGQGLIDQTEKTLRASGVTRIIRDYTTDTAVN
CCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHH
FASILTRVKGAHAAVIVYGGADAQAGPMVRQMKALGIDAAFVGSDGVCTGQWTALSSGAN
HHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCEEEECCCCC
EGQFCTQAGDPRARMAGYAAFERRFEARYGKVIVFAPYGYDAVMLLADAMRRANSTEPAA
CCCEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHCCCCCHHH
LLGALATTRYDGVIGRIRFSPQGDNLNGAVTVYRVQRGALVPVSD
HHHHHHHHHHCCEEEEEEECCCCCCCCCEEEEEEEECCCEEECCC
>Mature Secondary Structure 
SIHAESDWASEPIDSFEAARQSKIVTFSRARVDMNVRMGCLSLLAAVAFDAHAQSSVVR
CCCCCCCCCCCCHHHHHHHHHCCEEEEEEEEEECHHHHHHHHHHHHHHHCCCCCCCEEE
IGVAMPLTGPVAHLGKDVQNGAQLAVDELNRAPPTIEGKPVKFVLVVEDDQGDPRQAVQV
EEEECCCCCHHHHHCHHHHCCHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCHHHHHHH
AQRLVDARVAGVVGDLNSGPTIVAAKVYAAAGIAQIAPAATHPAYTQLGYKTAFRLMATD
HHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHCHHHHCCCCCCCHHHHHHHHHEEEEEECC
NQQGASLAGLAAKLAKGRPIALIDDRGAYGQGLIDQTEKTLRASGVTRIIRDYTTDTAVN
CCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHH
FASILTRVKGAHAAVIVYGGADAQAGPMVRQMKALGIDAAFVGSDGVCTGQWTALSSGAN
HHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCEEEECCCCC
EGQFCTQAGDPRARMAGYAAFERRFEARYGKVIVFAPYGYDAVMLLADAMRRANSTEPAA
CCCEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHCCCCCHHH
LLGALATTRYDGVIGRIRFSPQGDNLNGAVTVYRVQRGALVPVSD
HHHHHHHHHHCCEEEEEEECCCCCCCCCEEEEEEEECCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA