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The map label for this gene is mmgB [H]

Identifier: 237811741

GI number: 237811741

Start: 1418227

End: 1419345

Strand: Direct

Name: mmgB [H]

Synonym: GBP346_A1479

Alternate gene names: 237811741

Gene position: 1418227-1419345 (Clockwise)

Preceding gene: 237811740

Following gene: 237811744

Centisome position: 34.6

GC content: 70.06

Gene sequence:

>1119_bases
GTGCGCGTGCACGGCGAGGGCCGCGCGAATCGAAACAACCGCATGACGCTTCGGCGCGCAGGCGGTTTTTTTGCGACGGG
CAGGCGCGCGCGGGCGGCCGCGCGCGTGCGGCGGCGGCCGGACGGACTCGGCGCGTCGCGCAGCCAGGGTGGTTCGATGC
GACAATCGTGCGCACATTCGAACATCTTGGAGACCCCGCCCATGAAGATTCAGCGGATCGCCGTCGTCGGCGCCGGCGTG
ATCGGCGCGAGCTGGACCGCGTTCTATTTGTCGAAGGGCTTCGACGTCGCCGTGACCGATCCCGCGCCCGGCGCGCGCGA
GCGGCTCGACGCCGCGCTTGCGAATTTTCTAGGCGAGCGCGCCGGCACGCTCGCGTCGCGCGTGGCGTTCGAGCCGACGC
TCGACGCCGCGCTCGAAGGCGCGGACTTCGTGCAGGAGAACGGCCCCGAGCGTCTCGATTTCAAGCGCGAGCTGTATCGC
CGGATCGACGCGCGCCTGCCCGCGCACGTGCTCGTCGCATCGAGCTCGTCCGGGCTCAAGATGTCCGATATCCAGACCGC
GTGCGACGCGCATCCGCAGCGCTGCCTCGTCGCGCATCCGTTCAATCCGCCGCACCTGATTCCGCTCGTCGAACTCGTCG
GCGGCGCGGCGACGTCGGCCGACGCGATCGCGCGGGCGAAGCGCTTCTACGACAGCCTCGGCAAGGTGACGATCGTGCTC
AACAAGGAGAGGGCGGGCCACGTCGCGAACCGGCTCGCGGCCGCGCTCTTTCGCGAGGTGTATTACCTGGTGGGCGAAGG
CGTCGTGAGCGTCGAGGACGCGGACAAGGCGGTGTCGTGGGGGCCCGGCCTGCGTTGGGGGCTGATGGGGCAGAGCCTCG
TCTACCACCTCGGCGGCGGAGAGGGCGGCATCGCGCATTTCCTCGAGCACCTGTCGGGCCCGATGGCGAGCTGGTGGAAC
GACCTCGGCGCGCCGTCGTTCTCGCCCGACGTCGATCGCCAACTGATCGACGCGCTGCGCGAGATCCAGGGCGCGCATTC
GATGCGCGAGCTCGGCGCGGAGCGCGACCGTCTGCTCGTCGAGCTGATCGACGCACGGCGCAACAGCTTTCTGCCGTAG

Upstream 100 bases:

>100_bases
GGCTGAGCAACGCGGCAAATCGCGAGCACGCCGCGCGGCGGCGACGCGGCCGGGACGGCGCGCGCCGGAGCCGCGCGCGA
GATATGCCGCTCGCGCCGCC

Downstream 100 bases:

>100_bases
GCGTCGCACGCCGGTCGCGGTGCGCCCCCACCGTACACGGCGGCGTGCGGCGGCATACGGCGGCGTGCGCCGGCGGCACG
CGGCGGCGCGGCATCGAGCG

Product: 3-hydroxyacyl-CoA dehydrogenase NAD binding domain/C- domain protein

Products: NA

Alternate protein names: Beta-hydroxybutyryl-CoA dehydrogenase; BHBD [H]

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MRVHGEGRANRNNRMTLRRAGGFFATGRRARAAARVRRRPDGLGASRSQGGSMRQSCAHSNILETPPMKIQRIAVVGAGV
IGASWTAFYLSKGFDVAVTDPAPGARERLDAALANFLGERAGTLASRVAFEPTLDAALEGADFVQENGPERLDFKRELYR
RIDARLPAHVLVASSSSGLKMSDIQTACDAHPQRCLVAHPFNPPHLIPLVELVGGAATSADAIARAKRFYDSLGKVTIVL
NKERAGHVANRLAAALFREVYYLVGEGVVSVEDADKAVSWGPGLRWGLMGQSLVYHLGGGEGGIAHFLEHLSGPMASWWN
DLGAPSFSPDVDRQLIDALREIQGAHSMRELGAERDRLLVELIDARRNSFLP

Sequences:

>Translated_372_residues
MRVHGEGRANRNNRMTLRRAGGFFATGRRARAAARVRRRPDGLGASRSQGGSMRQSCAHSNILETPPMKIQRIAVVGAGV
IGASWTAFYLSKGFDVAVTDPAPGARERLDAALANFLGERAGTLASRVAFEPTLDAALEGADFVQENGPERLDFKRELYR
RIDARLPAHVLVASSSSGLKMSDIQTACDAHPQRCLVAHPFNPPHLIPLVELVGGAATSADAIARAKRFYDSLGKVTIVL
NKERAGHVANRLAAALFREVYYLVGEGVVSVEDADKAVSWGPGLRWGLMGQSLVYHLGGGEGGIAHFLEHLSGPMASWWN
DLGAPSFSPDVDRQLIDALREIQGAHSMRELGAERDRLLVELIDARRNSFLP
>Mature_372_residues
MRVHGEGRANRNNRMTLRRAGGFFATGRRARAAARVRRRPDGLGASRSQGGSMRQSCAHSNILETPPMKIQRIAVVGAGV
IGASWTAFYLSKGFDVAVTDPAPGARERLDAALANFLGERAGTLASRVAFEPTLDAALEGADFVQENGPERLDFKRELYR
RIDARLPAHVLVASSSSGLKMSDIQTACDAHPQRCLVAHPFNPPHLIPLVELVGGAATSADAIARAKRFYDSLGKVTIVL
NKERAGHVANRLAAALFREVYYLVGEGVVSVEDADKAVSWGPGLRWGLMGQSLVYHLGGGEGGIAHFLEHLSGPMASWWN
DLGAPSFSPDVDRQLIDALREIQGAHSMRELGAERDRLLVELIDARRNSFLP

Specific function: Butyrate/butanol-producing pathway. Phenylacetic acid aerobic catabolism. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Mitochondria or Peroxisomes [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI115430219, Length=270, Percent_Identity=34.4444444444444, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI20127408, Length=223, Percent_Identity=28.2511210762332, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI296179429, Length=233, Percent_Identity=27.0386266094421, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1787661, Length=243, Percent_Identity=27.9835390946502, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788682, Length=137, Percent_Identity=31.3868613138686, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115533614, Length=247, Percent_Identity=31.1740890688259, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI193203623, Length=247, Percent_Identity=32.3886639676113, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI25144276, Length=210, Percent_Identity=27.6190476190476, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17508953, Length=210, Percent_Identity=27.6190476190476, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17508951, Length=210, Percent_Identity=27.6190476190476, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17549919, Length=234, Percent_Identity=25.2136752136752, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17553560, Length=241, Percent_Identity=24.4813278008299, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17558304, Length=210, Percent_Identity=27.1428571428571, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI20129993, Length=315, Percent_Identity=30.7936507936508, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI45549573, Length=309, Percent_Identity=28.4789644012945, Blast_Score=131, Evalue=6e-31,
Organism=Drosophila melanogaster, GI19921000, Length=233, Percent_Identity=26.6094420600858, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24583077, Length=233, Percent_Identity=26.6094420600858, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24583079, Length=233, Percent_Identity=26.6094420600858, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022694
- InterPro:   IPR006180
- InterPro:   IPR006176
- InterPro:   IPR006108
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00725 3HCDH; PF02737 3HCDH_N [H]

EC number: =1.1.1.157 [H]

Molecular weight: Translated: 40256; Mature: 40256

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVHGEGRANRNNRMTLRRAGGFFATGRRARAAARVRRRPDGLGASRSQGGSMRQSCAHS
CCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHC
NILETPPMKIQRIAVVGAGVIGASWTAFYLSKGFDVAVTDPAPGARERLDAALANFLGER
CCCCCCCHHHEEEHEEECCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHH
AGTLASRVAFEPTLDAALEGADFVQENGPERLDFKRELYRRIDARLPAHVLVASSSSGLK
HHHHHHHHCCCCCHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCC
MSDIQTACDAHPQRCLVAHPFNPPHLIPLVELVGGAATSADAIARAKRFYDSLGKVTIVL
HHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEE
NKERAGHVANRLAAALFREVYYLVGEGVVSVEDADKAVSWGPGLRWGLMGQSLVYHLGGG
ECCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHCCCHHEEEECCC
EGGIAHFLEHLSGPMASWWNDLGAPSFSPDVDRQLIDALREIQGAHSMRELGAERDRLLV
CCHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ELIDARRNSFLP
HHHHHHHHCCCC
>Mature Secondary Structure
MRVHGEGRANRNNRMTLRRAGGFFATGRRARAAARVRRRPDGLGASRSQGGSMRQSCAHS
CCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHC
NILETPPMKIQRIAVVGAGVIGASWTAFYLSKGFDVAVTDPAPGARERLDAALANFLGER
CCCCCCCHHHEEEHEEECCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHH
AGTLASRVAFEPTLDAALEGADFVQENGPERLDFKRELYRRIDARLPAHVLVASSSSGLK
HHHHHHHHCCCCCHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCC
MSDIQTACDAHPQRCLVAHPFNPPHLIPLVELVGGAATSADAIARAKRFYDSLGKVTIVL
HHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEE
NKERAGHVANRLAAALFREVYYLVGEGVVSVEDADKAVSWGPGLRWGLMGQSLVYHLGGG
ECCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHCCCHHEEEECCC
EGGIAHFLEHLSGPMASWWNDLGAPSFSPDVDRQLIDALREIQGAHSMRELGAERDRLLV
CCHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ELIDARRNSFLP
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]