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The map label for this gene is cbaA [H]

Identifier: 237811638

GI number: 237811638

Start: 1322608

End: 1324212

Strand: Direct

Name: cbaA [H]

Synonym: GBP346_A1375

Alternate gene names: 237811638

Gene position: 1322608-1324212 (Clockwise)

Preceding gene: 237811637

Following gene: 237811639

Centisome position: 32.27

GC content: 66.11

Gene sequence:

>1605_bases
GTGCTCGCGCACTTCTGGCTCGCGTTCGCGGTCTTCGGCGTCGCGCTGTTGCTCGGCGCGTGGCAGATGCTCGCGCGCAG
CCCGCTGCATCCGTGGCTCGGCAATCCCGAGCTCTACTACCGCTCGGTGACGGCGCACGGCTCCGTGATGGGCTATGTGT
TTCCGACGCTGATCGCGATGGGTTTCGGCTACGCGATCAGCGAGCTCGCGCTGAAGATGCCGCTCGTCGGCCGCCGCTGG
GCATGGACGGGCTTCTGGCTGATCGGGCTCGGCTCGGTCGTCGCGATGACGCCCGTGTCGCTCGGCCTGTCGTCGGTGCT
GTATACGTTCTATCCGCCGATGATCGGCAGCCCGTTCTACTACCTCGGCGTCGTGCTCGTCGTCGTCGGCTCGTGGATCT
GGGTCGCGCTGATGTCGGTGAACCTCTATGCGTGGAAGAAGCGCAATCCCGGCACGCCGATTCCGCTCGCGATGTTCGCC
AACGTCGCGGGCGCGTATCTGTGGGGCTGGACCGCGGTGGGCGCCGCGATCGAGATCCTGTTCCAGATCCTGCCCGTCGC
GGTCGGCCTGAAGACGACGATCGACGCGGGCCTCGCGCGCGTGTTCTTCTCGTGGACGCTGCACGCGATCGTCTACTTCT
GGCTGATTCCCGCGTACATCGCGTACTACACGCTCGTGCCGCGCGCGATCGGCGGCAAGCTGTACAGCGACGGGATGGCG
CGCATCTCGTTCATCCTGTTCCTCGTCGGCGCGATGCCGATCGGCGTGCACCACCTGTTCGCCGATCCGCAGGTCGGCTC
GGGCTTCAAGTTCCTGCAATCGGTGTTCACCGCGCTCGTCGCGGTGCCGACGCTGCTCACGGTATTTACGGTGTGCGCAT
CGGTCGAGATCGCCGCGCGCCTGCGCGGCGGCAAGGGCGCGTTCGGCTGGCTGCGCGCGCTGCCCTGGCACGAGCCGATG
ATGCTCGCCGTCGCGTTCTCGTTTGTGATGCTCGGCTTCGGCGGCGCGGGCGGGCTCATCAACATGAGCTATCAGCTCGA
TTCGACGATCCACAACACGCAGTGGATCACCGGGCACTTTCACCTGATCTTCGGCGGCGCCGTCGTCATCATGTACTTCG
CGATCGCGTATGAACTGTGGCCGCATCTGACGGGCCGCGCGCTCGGCAGCCTGCGGCTCGTGAAGGCGCAGCTCTGGCTG
TGGTTCATCGGGATGATCGTCACGACGTTCCCGTGGCACTACGTCGGCATTCTCGGCATGCCGCGCCGGATGGCCTACTA
CGACTACAGCGATCCGGCGCTCGCGCCGCAGGCGGCGTGGGTGATCATGTCGGTCGTCGGCGCGCTGATCCTCGTCGCGT
CGGCCGTGCTGTTCTTCGTCGTGCTGCTACGCAGCCATTGCGGCGCGAAGGTCAAGCCGGCCGAGTTCGCGTTCAGCTCG
GCCGTCCATGAGCCGAAGACGCTGCCCGTCGCGCTCAACAGCTTCGGGCTGTGGATCGCGCTGATGATCGGCCTCACGGT
CGTCAACTACGGCTATCCGATCGCGCAATTGATGTCGCTCAAGCAACCGTCGGTGCCGGCGATCTACATGGGGGCGCAGC
GATGA

Upstream 100 bases:

>100_bases
GAGGGGATGTGGGCGCACGTCAAGGTCATTGACCGTGCGGAATTCGACAAACTGGCGTCCAGCGCGCGGAGACTGAGCTG
TGTTAAAGAATAATCGACTG

Downstream 100 bases:

>100_bases
GCACGGAACGTCTGTTTTCGATTCGCAACCGCTGGTTGACGGTCAGCGTCGGGCTCACGCTGTTCGCGGTGGTCGCGTCG
GTGCTGATCGGCTTCGTCTG

Product: cytochrome c oxidase subunit 1

Products: NA

Alternate protein names: Cytochrome c ba(3) subunit I; Cytochrome c oxidase polypeptide I; Cytochrome cba3 subunit 1 [H]

Number of amino acids: Translated: 534; Mature: 534

Protein sequence:

>534_residues
MLAHFWLAFAVFGVALLLGAWQMLARSPLHPWLGNPELYYRSVTAHGSVMGYVFPTLIAMGFGYAISELALKMPLVGRRW
AWTGFWLIGLGSVVAMTPVSLGLSSVLYTFYPPMIGSPFYYLGVVLVVVGSWIWVALMSVNLYAWKKRNPGTPIPLAMFA
NVAGAYLWGWTAVGAAIEILFQILPVAVGLKTTIDAGLARVFFSWTLHAIVYFWLIPAYIAYYTLVPRAIGGKLYSDGMA
RISFILFLVGAMPIGVHHLFADPQVGSGFKFLQSVFTALVAVPTLLTVFTVCASVEIAARLRGGKGAFGWLRALPWHEPM
MLAVAFSFVMLGFGGAGGLINMSYQLDSTIHNTQWITGHFHLIFGGAVVIMYFAIAYELWPHLTGRALGSLRLVKAQLWL
WFIGMIVTTFPWHYVGILGMPRRMAYYDYSDPALAPQAAWVIMSVVGALILVASAVLFFVVLLRSHCGAKVKPAEFAFSS
AVHEPKTLPVALNSFGLWIALMIGLTVVNYGYPIAQLMSLKQPSVPAIYMGAQR

Sequences:

>Translated_534_residues
MLAHFWLAFAVFGVALLLGAWQMLARSPLHPWLGNPELYYRSVTAHGSVMGYVFPTLIAMGFGYAISELALKMPLVGRRW
AWTGFWLIGLGSVVAMTPVSLGLSSVLYTFYPPMIGSPFYYLGVVLVVVGSWIWVALMSVNLYAWKKRNPGTPIPLAMFA
NVAGAYLWGWTAVGAAIEILFQILPVAVGLKTTIDAGLARVFFSWTLHAIVYFWLIPAYIAYYTLVPRAIGGKLYSDGMA
RISFILFLVGAMPIGVHHLFADPQVGSGFKFLQSVFTALVAVPTLLTVFTVCASVEIAARLRGGKGAFGWLRALPWHEPM
MLAVAFSFVMLGFGGAGGLINMSYQLDSTIHNTQWITGHFHLIFGGAVVIMYFAIAYELWPHLTGRALGSLRLVKAQLWL
WFIGMIVTTFPWHYVGILGMPRRMAYYDYSDPALAPQAAWVIMSVVGALILVASAVLFFVVLLRSHCGAKVKPAEFAFSS
AVHEPKTLPVALNSFGLWIALMIGLTVVNYGYPIAQLMSLKQPSVPAIYMGAQR
>Mature_534_residues
MLAHFWLAFAVFGVALLLGAWQMLARSPLHPWLGNPELYYRSVTAHGSVMGYVFPTLIAMGFGYAISELALKMPLVGRRW
AWTGFWLIGLGSVVAMTPVSLGLSSVLYTFYPPMIGSPFYYLGVVLVVVGSWIWVALMSVNLYAWKKRNPGTPIPLAMFA
NVAGAYLWGWTAVGAAIEILFQILPVAVGLKTTIDAGLARVFFSWTLHAIVYFWLIPAYIAYYTLVPRAIGGKLYSDGMA
RISFILFLVGAMPIGVHHLFADPQVGSGFKFLQSVFTALVAVPTLLTVFTVCASVEIAARLRGGKGAFGWLRALPWHEPM
MLAVAFSFVMLGFGGAGGLINMSYQLDSTIHNTQWITGHFHLIFGGAVVIMYFAIAYELWPHLTGRALGSLRLVKAQLWL
WFIGMIVTTFPWHYVGILGMPRRMAYYDYSDPALAPQAAWVIMSVVGALILVASAVLFFVVLLRSHCGAKVKPAEFAFSS
AVHEPKTLPVALNSFGLWIALMIGLTVVNYGYPIAQLMSLKQPSVPAIYMGAQR

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. This Ubiquinol Oxidase Shows Proton Pump Activity Across The Membrane In Addition To The Electron T

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Escherichia coli, GI1786634, Length=483, Percent_Identity=24.4306418219462, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6226519, Length=283, Percent_Identity=28.2685512367491, Blast_Score=80, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 58601; Mature: 58601

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS50855 COX1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEECCCCC
>Mature Secondary Structure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HCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7657607; 10338009; 10775261 [H]