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The map label for this gene is ftsK [H]

Identifier: 229918680

GI number: 229918680

Start: 2929605

End: 2931797

Strand: Direct

Name: ftsK [H]

Synonym: EAT1b_2967

Alternate gene names: 229918680

Gene position: 2929605-2931797 (Clockwise)

Preceding gene: 229918679

Following gene: 229918681

Centisome position: 97.66

GC content: 49.48

Gene sequence:

>2193_bases
GTGGCTCAAAAAACAAGAAAGACTCCCGTAAAGCGAAAGCGACCAGCGACGCGAAATACGAGGAACCGTAAAAAACAACC
GATTGCGCCACGTACATATGGGTGGGGCATCTTTGTCCTCGCCATCGTCGCATTCGTATTTGCCTTATTTGATTTAGGGT
GGATTGGTCAACAGTTGTCCGATTTATCTGTCTATCTTTTCGGAGGATGGGATGCGCTCACTTACTTGATGATGGCTGTC
TTGTTATGGATTGTCCTCACTCCGATGAAGCCGATGCGACGAACGGGACTATTCGCGATGCTCGCCTCGTTCTTACTATT
TGGAGACTTACTTTGGGGAGAGGCGAGGGGTGGCATCAATGGCACTTTCTATAACTTGAATCAATATTTATTCTCTGACT
TCGGGATTGTCTTCTTAGGAATCGTCTGCTTCCTCGTCGGTGTCTCGCTCTATGCCCCAACGATTTGGGGAACGCTCTAT
CATCGAATGCAGGAATCCGTCACGGCCGTCAGAAAAGAATGGCAAGCCAGACCGAAAGTGGAAAAGCAGCAAGAGACGAA
ACGAACGCGCAAGACGTCACCTCGTCCAAAACAAGAGGAAACGCAGCCGGACGCGGAAATAGAGTCAGATGTGGTCACGA
TGCAAGACATTCCAATCGTCGGGTTTAGTGAAAAGGTCGTAGCGGAAAAAAGTGAGAAGAACAATCAGACTCGAACGGAT
TCTTCGGAAGTCGATTCCACGATCACGACCGAGGAGATGATGATGACTGCGGCCCAAGATGTCTCGGATACATACGAACT
TCCGCCATTCTCGAATTTGAAAGAACCCGTCATTACGGATTTGTCTGGTGAGAATGCGCGATTGAAAGAAAATGCATCCA
AGCTTGTAAAGACGCTTAAGTCATTCGGAGTCGGTGTCAAAGTGTTGAAGATCCACCTTGGTCCAACCGTCACGAAATAT
GAACTACAACCAGATATCGGTGTGAAGGTCAGTCGCATCACCTCATTGAGTGATGATTTGGCATTGGCGCTGGCTGCAAA
AGATATTCGGATTGAAGCTCCGATTCCCGGTAAAGCCGCAATTGGTATTGAAGTACCGAACCAGGAGGTCGCACCGGTAT
GCTTACGTGAAGTGCTAGAGGCAGAACCGGTGAAACAAGATGACTCGAAGCTGCTCGTCGCACTCGGTCGTAGTATCAGT
GGCGAGACGGTTGGGATCTCGCTCAACAAAATGCCGCATTTGCTTGTCGCAGGATCGACAGGGTCTGGGAAATCCGTCTG
TATCAATGGCATGATCGTGTCACTCTTGATGCGTTCTCGACCCGATGAGGTCCGACTTATGATGATTGATCCGAAGATGG
TCGAGTTGAACGTCTATAACGGTGTGCCACACCTGTTGACACCGGTCGTCACCGATCCGAAAAAAGCCGCACAAGCACTG
AAGCAGGTCGTCGCAGAGATGGAACGACGATATGAACTGTTCAGTCGATATGGAGTTCGCAATATCGAAGGGTACAATGA
ACTCGTCGATCAGTCAGATGACGAGGATGCGAAACGTTTACCGTTCATCGTTGTGATCGTCGATGAATTGGCGGACTTGA
TGATGGTCGCATCAAATGACGTCGAAGATGCCATCATGCGACTTGCACAAATGGCACGTGCTGCCGGCATTCACATGGTC
CTCGCGACACAACGTCCATCTGTCGACGTCATCACAGGCGTCATCAAGGCGAACATTCCGTCCCGCATCGCTTTCGCCGT
CTCATCGCAAACCGATTCAAGGACCATTCTTGATGGCGGGGGAGCAGAAAAACTGCTTGGACGCGGTGACATGTTGATGC
TTGCGAACGGAATGAACAAGCCGGTCCGTGTACAAGGTGCATTCGTCTCCGATCAAGAAGTCGAGACGGTCGTCAATCAT
GTCATCGCGCAGCAGCGTGCGCAATATGTGGAAGCGATGATGCCAAAAGAAGAAGAAGTGACGACGATTGACTCGGATGA
TTCATTGTTCGGAGAAGTCGTGCAATTCATCGTGACACAAGAGACGGCATCTACTTCGATGATTCAACGTAGATTTCGAA
TCGGGTATAATCGTGCCGCCCGTTTGATTGACTCACTTGAGGAAGCGGGGTATGTCGGTCCGTCAGAAGGTTCAAAACCG
AGGAAAGTACTCATTCAAGAACAAGAAGAATAA

Upstream 100 bases:

>100_bases
CGTCGTCCGATGATCTTGCCGATCATCATGGAGATTTAATGGAATGAGAGTGAGGCAAAAGTCATCTGACTTTTGCCTTC
TTTTTTTAGGAGGAACTGAT

Downstream 100 bases:

>100_bases
TCACAAAAACGAACGATTATATATCGATATATATAATCGTTCGTTTTTTAATACTGTATATACGATATAATAATATTCGC
TCTATTCTGAGATGTTCGCT

Product: cell divisionFtsK/SpoIIIE

Products: NA

Alternate protein names: DNA translocase SpoIIIE; Stage III sporulation protein E [H]

Number of amino acids: Translated: 730; Mature: 729

Protein sequence:

>730_residues
MAQKTRKTPVKRKRPATRNTRNRKKQPIAPRTYGWGIFVLAIVAFVFALFDLGWIGQQLSDLSVYLFGGWDALTYLMMAV
LLWIVLTPMKPMRRTGLFAMLASFLLFGDLLWGEARGGINGTFYNLNQYLFSDFGIVFLGIVCFLVGVSLYAPTIWGTLY
HRMQESVTAVRKEWQARPKVEKQQETKRTRKTSPRPKQEETQPDAEIESDVVTMQDIPIVGFSEKVVAEKSEKNNQTRTD
SSEVDSTITTEEMMMTAAQDVSDTYELPPFSNLKEPVITDLSGENARLKENASKLVKTLKSFGVGVKVLKIHLGPTVTKY
ELQPDIGVKVSRITSLSDDLALALAAKDIRIEAPIPGKAAIGIEVPNQEVAPVCLREVLEAEPVKQDDSKLLVALGRSIS
GETVGISLNKMPHLLVAGSTGSGKSVCINGMIVSLLMRSRPDEVRLMMIDPKMVELNVYNGVPHLLTPVVTDPKKAAQAL
KQVVAEMERRYELFSRYGVRNIEGYNELVDQSDDEDAKRLPFIVVIVDELADLMMVASNDVEDAIMRLAQMARAAGIHMV
LATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDGGGAEKLLGRGDMLMLANGMNKPVRVQGAFVSDQEVETVVNH
VIAQQRAQYVEAMMPKEEEVTTIDSDDSLFGEVVQFIVTQETASTSMIQRRFRIGYNRAARLIDSLEEAGYVGPSEGSKP
RKVLIQEQEE

Sequences:

>Translated_730_residues
MAQKTRKTPVKRKRPATRNTRNRKKQPIAPRTYGWGIFVLAIVAFVFALFDLGWIGQQLSDLSVYLFGGWDALTYLMMAV
LLWIVLTPMKPMRRTGLFAMLASFLLFGDLLWGEARGGINGTFYNLNQYLFSDFGIVFLGIVCFLVGVSLYAPTIWGTLY
HRMQESVTAVRKEWQARPKVEKQQETKRTRKTSPRPKQEETQPDAEIESDVVTMQDIPIVGFSEKVVAEKSEKNNQTRTD
SSEVDSTITTEEMMMTAAQDVSDTYELPPFSNLKEPVITDLSGENARLKENASKLVKTLKSFGVGVKVLKIHLGPTVTKY
ELQPDIGVKVSRITSLSDDLALALAAKDIRIEAPIPGKAAIGIEVPNQEVAPVCLREVLEAEPVKQDDSKLLVALGRSIS
GETVGISLNKMPHLLVAGSTGSGKSVCINGMIVSLLMRSRPDEVRLMMIDPKMVELNVYNGVPHLLTPVVTDPKKAAQAL
KQVVAEMERRYELFSRYGVRNIEGYNELVDQSDDEDAKRLPFIVVIVDELADLMMVASNDVEDAIMRLAQMARAAGIHMV
LATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDGGGAEKLLGRGDMLMLANGMNKPVRVQGAFVSDQEVETVVNH
VIAQQRAQYVEAMMPKEEEVTTIDSDDSLFGEVVQFIVTQETASTSMIQRRFRIGYNRAARLIDSLEEAGYVGPSEGSKP
RKVLIQEQEE
>Mature_729_residues
AQKTRKTPVKRKRPATRNTRNRKKQPIAPRTYGWGIFVLAIVAFVFALFDLGWIGQQLSDLSVYLFGGWDALTYLMMAVL
LWIVLTPMKPMRRTGLFAMLASFLLFGDLLWGEARGGINGTFYNLNQYLFSDFGIVFLGIVCFLVGVSLYAPTIWGTLYH
RMQESVTAVRKEWQARPKVEKQQETKRTRKTSPRPKQEETQPDAEIESDVVTMQDIPIVGFSEKVVAEKSEKNNQTRTDS
SEVDSTITTEEMMMTAAQDVSDTYELPPFSNLKEPVITDLSGENARLKENASKLVKTLKSFGVGVKVLKIHLGPTVTKYE
LQPDIGVKVSRITSLSDDLALALAAKDIRIEAPIPGKAAIGIEVPNQEVAPVCLREVLEAEPVKQDDSKLLVALGRSISG
ETVGISLNKMPHLLVAGSTGSGKSVCINGMIVSLLMRSRPDEVRLMMIDPKMVELNVYNGVPHLLTPVVTDPKKAAQALK
QVVAEMERRYELFSRYGVRNIEGYNELVDQSDDEDAKRLPFIVVIVDELADLMMVASNDVEDAIMRLAQMARAAGIHMVL
ATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDGGGAEKLLGRGDMLMLANGMNKPVRVQGAFVSDQEVETVVNHV
IAQQRAQYVEAMMPKEEEVTTIDSDDSLFGEVVQFIVTQETASTSMIQRRFRIGYNRAARLIDSLEEAGYVGPSEGSKPR
KVLIQEQEE

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=483, Percent_Identity=50.3105590062112, Blast_Score=424, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 80906; Mature: 80774

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQKTRKTPVKRKRPATRNTRNRKKQPIAPRTYGWGIFVLAIVAFVFALFDLGWIGQQLS
CCCCCCCCCCHHCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
DLSVYLFGGWDALTYLMMAVLLWIVLTPMKPMRRTGLFAMLASFLLFGDLLWGEARGGIN
CCEEEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GTFYNLNQYLFSDFGIVFLGIVCFLVGVSLYAPTIWGTLYHRMQESVTAVRKEWQARPKV
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EKQQETKRTRKTSPRPKQEETQPDAEIESDVVTMQDIPIVGFSEKVVAEKSEKNNQTRTD
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHCEEEECCCCEECCCHHHHHHHHHCCCCCCCC
SSEVDSTITTEEMMMTAAQDVSDTYELPPFSNLKEPVITDLSGENARLKENASKLVKTLK
HHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHH
SFGVGVKVLKIHLGPTVTKYELQPDIGVKVSRITSLSDDLALALAAKDIRIEAPIPGKAA
HHCCCEEEEEEECCCCEEEEEECCCCCCCHHHHHHCCHHHHHEEEECCEEEECCCCCCEE
IGIEVPNQEVAPVCLREVLEAEPVKQDDSKLLVALGRSISGETVGISLNKMPHLLVAGST
EEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCEEEEECCC
GSGKSVCINGMIVSLLMRSRPDEVRLMMIDPKMVELNVYNGVPHLLTPVVTDPKKAAQAL
CCCCCEEHHHHHHHHHHHCCCCCEEEEEECCEEEEEEECCCCHHHHCCCCCCHHHHHHHH
KQVVAEMERRYELFSRYGVRNIEGYNELVDQSDDEDAKRLPFIVVIVDELADLMMVASND
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCHHHCCEEEEEHHHHHHHHHHHCCC
VEDAIMRLAQMARAAGIHMVLATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDGG
HHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEECCC
GAEKLLGRGDMLMLANGMNKPVRVQGAFVSDQEVETVVNHVIAQQRAQYVEAMMPKEEEV
CHHHHHCCCCEEEEECCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TTIDSDDSLFGEVVQFIVTQETASTSMIQRRFRIGYNRAARLIDSLEEAGYVGPSEGSKP
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCC
RKVLIQEQEE
CEECCCCCCC
>Mature Secondary Structure 
AQKTRKTPVKRKRPATRNTRNRKKQPIAPRTYGWGIFVLAIVAFVFALFDLGWIGQQLS
CCCCCCCCCHHCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
DLSVYLFGGWDALTYLMMAVLLWIVLTPMKPMRRTGLFAMLASFLLFGDLLWGEARGGIN
CCEEEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GTFYNLNQYLFSDFGIVFLGIVCFLVGVSLYAPTIWGTLYHRMQESVTAVRKEWQARPKV
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EKQQETKRTRKTSPRPKQEETQPDAEIESDVVTMQDIPIVGFSEKVVAEKSEKNNQTRTD
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHCEEEECCCCEECCCHHHHHHHHHCCCCCCCC
SSEVDSTITTEEMMMTAAQDVSDTYELPPFSNLKEPVITDLSGENARLKENASKLVKTLK
HHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHH
SFGVGVKVLKIHLGPTVTKYELQPDIGVKVSRITSLSDDLALALAAKDIRIEAPIPGKAA
HHCCCEEEEEEECCCCEEEEEECCCCCCCHHHHHHCCHHHHHEEEECCEEEECCCCCCEE
IGIEVPNQEVAPVCLREVLEAEPVKQDDSKLLVALGRSISGETVGISLNKMPHLLVAGST
EEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCEEEEECCC
GSGKSVCINGMIVSLLMRSRPDEVRLMMIDPKMVELNVYNGVPHLLTPVVTDPKKAAQAL
CCCCCEEHHHHHHHHHHHCCCCCEEEEEECCEEEEEEECCCCHHHHCCCCCCHHHHHHHH
KQVVAEMERRYELFSRYGVRNIEGYNELVDQSDDEDAKRLPFIVVIVDELADLMMVASND
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCHHHCCEEEEEHHHHHHHHHHHCCC
VEDAIMRLAQMARAAGIHMVLATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDGG
HHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEECCC
GAEKLLGRGDMLMLANGMNKPVRVQGAFVSDQEVETVVNHVIAQQRAQYVEAMMPKEEEV
CHHHHHCCCCEEEEECCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TTIDSDDSLFGEVVQFIVTQETASTSMIQRRFRIGYNRAARLIDSLEEAGYVGPSEGSKP
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCC
RKVLIQEQEE
CEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3129532; 2507870; 9384377; 8160014; 10588743; 11062134; 11778051 [H]