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The map label for this gene is ctaD [H]

Identifier: 229918523

GI number: 229918523

Start: 2778442

End: 2780328

Strand: Direct

Name: ctaD [H]

Synonym: EAT1b_2810

Alternate gene names: 229918523

Gene position: 2778442-2780328 (Clockwise)

Preceding gene: 229918522

Following gene: 229918524

Centisome position: 92.62

GC content: 49.18

Gene sequence:

>1887_bases
GTGGCACAGACCACTGCAATGCAGCAATCGCGTAAATACAATGGCATCATGGATTGGATTACGACGGTTGACCACAAAAA
AATCGGTATTTTGTATTTGTTCTCAGGAATCTTCTTCCTCCTTCTCGGTGGAATTGAAGCATTACTGATTCGTTGGCAAC
TCGTCAAACCAATGAACGACTTCGTCAGCGGTGAGACGTTTAACCAGTTGATTACGATGCACGGAACGACGATGATCTTC
CTTGCGGCCATGCCGATGTTATTCGGTTTCATGAACGCCGTCGTACCACTTCAAATCGGGGCACGCGACGTTGCGTTCCC
ATTCATTAACTCATTAGGTTTTTGGTTGTTCTTCTTCGGTGGAGTCATGCTTAACTTGAGCTGGTTCTTCGGAGCAGCAC
CAAACGCAGGGTGGACGGCTTACGCTCCACTTTCAACACAACCGGAAGCGACAGGGGTAGACTTCTACGCTCTCGGTCTT
CAGATTTCAGGTTTCGGTTCATTGATGGCCGGGATTAACTTCCTCGTCACCATCTTGAACATGCGTGCGCCAGGAATGAA
ACTCATGCGTATGCCACTCTTCACATGGACGACTTTCGTTGCATCGGCATTGATCGTCTTCGCCTTCCCACCACTTACGG
TCGGATTGTTCATGTTGATGTTCGAGCGACTCTTCGGAGCTGCTTATTTTGACCCGGCACTTGGCGGGAACGTTGTTATC
TGGGAACACCTTTTCTGGATCTTCGGTCACCCGGAGGTATACATCTTGATCTTACCGGCATTCGGTATTTTCTCGGAAAT
CATTCCGACATTTGCGCGTAAACGCCTCTTCGGTTACACGACGATGGTCTTTGCGACAATGCTCATCGGTTTCCTTGGAT
TCATGGTTTGGGTTCACCACATGTTCACAGTCGGTCTTGGTCCGGTTGCCAACTCGATCTTCGCTGTTGCAACGATGGCG
ATTGCCGTACCAACGGGTGTTAAAATCTTTAACTGGCTCTTCACACTGTGGGGCGGTCAAATTAAATTCAACGTCGCCAT
GCTTTACTCAGTCGCGTTCATTCCTTCATTCCTCGTAGGTGGGATGACAGGGGTTATGCTCTCAGTCGCACCGGCTGACT
ATCAGTACCACGACAGCTACTTCGTTGTCGCTCACTTCCACTATGTAATCGTAGGTGGGGTTGTATACGGTCTCTTCGCA
GGACTTTACTACTGGTTCCCACTCATGTTCGGAAAAGCCCTTTCTGAAAAGCTTGGCTACTGGCAGTTCTGGTTGTTCTT
TATCGGGTTCCACTTGACGTTCTTCCCGCAACATTTCCTCGGATTGTTCGGTATGCCACGTCGAGTCTTCACATACCTCG
ATGGTCAAGGTTGGGATACACTCAACATGCTCTCGACAATCGGGGCATTCTTCATGGGTGTGTCAACGATTGTCTTGCTC
GTCGCTGTTGTGAAAGCTTTCTTGTCGAAAGACCGCGTCAAACCAGACCACTGGGGAGATGGACGTACGCTTGAGTGGAC
ACTTCCTGTTCCGACTCCAGAGTACAACTTTGCACAAACACCACTCGTCAAAGGACTTGATACGTTCTGGCTCGAGAAAA
TGGCTGGCAACAAACGCGTGTCAGTCGCTGAAGAAGTTTCGGACATCCACATGCCGAACAACTCGCTCATTCCGTTCTTC
ATGTCACTCGGCCTCTTTATCGCAGGACTCGGTGCCATCTTCCAGATGGATAACACGGTCGTCGGTTGGTCATTGATTGG
ATTTGGATTAGCGATGACGTTCGTCTCGATGTTCCTACGTTCTTGGATTGACGATCACGGCTACTACATTCCGAAGTCAC
AAGTCGAAGCAGACTTGAAAGCGATTCGTGAGAAAGGAGAACAATAA

Upstream 100 bases:

>100_bases
CAGGATTCAATGAAGGTCAAATCAGCAACGAAGAATTAGATGCACTCGTTGACTTCTTGTATGAGCAGAAGATTGACTAA
CGGGAAAAGGGGGATTTCAC

Downstream 100 bases:

>100_bases
ATGGCACATGCAGTTGAAAAACACCCAGTGACCGGTATCCCGGCCAATCCAGAGAAAGCAACACTGGAAGGGAAAAATAA
ATATGTGGCCTTCTGGTTCT

Product: cytochrome c oxidase, subunit I

Products: NA

Alternate protein names: Caa-3605 subunit 1; Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1 [H]

Number of amino acids: Translated: 628; Mature: 627

Protein sequence:

>628_residues
MAQTTAMQQSRKYNGIMDWITTVDHKKIGILYLFSGIFFLLLGGIEALLIRWQLVKPMNDFVSGETFNQLITMHGTTMIF
LAAMPMLFGFMNAVVPLQIGARDVAFPFINSLGFWLFFFGGVMLNLSWFFGAAPNAGWTAYAPLSTQPEATGVDFYALGL
QISGFGSLMAGINFLVTILNMRAPGMKLMRMPLFTWTTFVASALIVFAFPPLTVGLFMLMFERLFGAAYFDPALGGNVVI
WEHLFWIFGHPEVYILILPAFGIFSEIIPTFARKRLFGYTTMVFATMLIGFLGFMVWVHHMFTVGLGPVANSIFAVATMA
IAVPTGVKIFNWLFTLWGGQIKFNVAMLYSVAFIPSFLVGGMTGVMLSVAPADYQYHDSYFVVAHFHYVIVGGVVYGLFA
GLYYWFPLMFGKALSEKLGYWQFWLFFIGFHLTFFPQHFLGLFGMPRRVFTYLDGQGWDTLNMLSTIGAFFMGVSTIVLL
VAVVKAFLSKDRVKPDHWGDGRTLEWTLPVPTPEYNFAQTPLVKGLDTFWLEKMAGNKRVSVAEEVSDIHMPNNSLIPFF
MSLGLFIAGLGAIFQMDNTVVGWSLIGFGLAMTFVSMFLRSWIDDHGYYIPKSQVEADLKAIREKGEQ

Sequences:

>Translated_628_residues
MAQTTAMQQSRKYNGIMDWITTVDHKKIGILYLFSGIFFLLLGGIEALLIRWQLVKPMNDFVSGETFNQLITMHGTTMIF
LAAMPMLFGFMNAVVPLQIGARDVAFPFINSLGFWLFFFGGVMLNLSWFFGAAPNAGWTAYAPLSTQPEATGVDFYALGL
QISGFGSLMAGINFLVTILNMRAPGMKLMRMPLFTWTTFVASALIVFAFPPLTVGLFMLMFERLFGAAYFDPALGGNVVI
WEHLFWIFGHPEVYILILPAFGIFSEIIPTFARKRLFGYTTMVFATMLIGFLGFMVWVHHMFTVGLGPVANSIFAVATMA
IAVPTGVKIFNWLFTLWGGQIKFNVAMLYSVAFIPSFLVGGMTGVMLSVAPADYQYHDSYFVVAHFHYVIVGGVVYGLFA
GLYYWFPLMFGKALSEKLGYWQFWLFFIGFHLTFFPQHFLGLFGMPRRVFTYLDGQGWDTLNMLSTIGAFFMGVSTIVLL
VAVVKAFLSKDRVKPDHWGDGRTLEWTLPVPTPEYNFAQTPLVKGLDTFWLEKMAGNKRVSVAEEVSDIHMPNNSLIPFF
MSLGLFIAGLGAIFQMDNTVVGWSLIGFGLAMTFVSMFLRSWIDDHGYYIPKSQVEADLKAIREKGEQ
>Mature_627_residues
AQTTAMQQSRKYNGIMDWITTVDHKKIGILYLFSGIFFLLLGGIEALLIRWQLVKPMNDFVSGETFNQLITMHGTTMIFL
AAMPMLFGFMNAVVPLQIGARDVAFPFINSLGFWLFFFGGVMLNLSWFFGAAPNAGWTAYAPLSTQPEATGVDFYALGLQ
ISGFGSLMAGINFLVTILNMRAPGMKLMRMPLFTWTTFVASALIVFAFPPLTVGLFMLMFERLFGAAYFDPALGGNVVIW
EHLFWIFGHPEVYILILPAFGIFSEIIPTFARKRLFGYTTMVFATMLIGFLGFMVWVHHMFTVGLGPVANSIFAVATMAI
AVPTGVKIFNWLFTLWGGQIKFNVAMLYSVAFIPSFLVGGMTGVMLSVAPADYQYHDSYFVVAHFHYVIVGGVVYGLFAG
LYYWFPLMFGKALSEKLGYWQFWLFFIGFHLTFFPQHFLGLFGMPRRVFTYLDGQGWDTLNMLSTIGAFFMGVSTIVLLV
AVVKAFLSKDRVKPDHWGDGRTLEWTLPVPTPEYNFAQTPLVKGLDTFWLEKMAGNKRVSVAEEVSDIHMPNNSLIPFFM
SLGLFIAGLGAIFQMDNTVVGWSLIGFGLAMTFVSMFLRSWIDDHGYYIPKSQVEADLKAIREKGEQ

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=515, Percent_Identity=42.7184466019417, Blast_Score=380, Evalue=1e-105,
Organism=Escherichia coli, GI1786634, Length=607, Percent_Identity=44.8105436573311, Blast_Score=503, Evalue=1e-143,
Organism=Saccharomyces cerevisiae, GI6226519, Length=466, Percent_Identity=44.4206008583691, Blast_Score=388, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6226524, Length=323, Percent_Identity=42.7244582043344, Blast_Score=261, Evalue=2e-70,
Organism=Saccharomyces cerevisiae, GI6226523, Length=247, Percent_Identity=35.6275303643725, Blast_Score=149, Evalue=9e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 70480; Mature: 70349

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQTTAMQQSRKYNGIMDWITTVDHKKIGILYLFSGIFFLLLGGIEALLIRWQLVKPMND
CCCCHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVSGETFNQLITMHGTTMIFLAAMPMLFGFMNAVVPLQIGARDVAFPFINSLGFWLFFFG
HHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
GVMLNLSWFFGAAPNAGWTAYAPLSTQPEATGVDFYALGLQISGFGSLMAGINFLVTILN
HHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCEEEECEEECCHHHHHHHHHHHHHHHH
MRAPGMKLMRMPLFTWTTFVASALIVFAFPPLTVGLFMLMFERLFGAAYFDPALGGNVVI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHCCCCCCCCEEH
WEHLFWIFGHPEVYILILPAFGIFSEIIPTFARKRLFGYTTMVFATMLIGFLGFMVWVHH
HHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MFTVGLGPVANSIFAVATMAIAVPTGVKIFNWLFTLWGGQIKFNVAMLYSVAFIPSFLVG
HHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHH
GMTGVMLSVAPADYQYHDSYFVVAHFHYVIVGGVVYGLFAGLYYWFPLMFGKALSEKLGY
HHHHHHHEECCCCCEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WQFWLFFIGFHLTFFPQHFLGLFGMPRRVFTYLDGQGWDTLNMLSTIGAFFMGVSTIVLL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
VAVVKAFLSKDRVKPDHWGDGRTLEWTLPVPTPEYNFAQTPLVKGLDTFWLEKMAGNKRV
HHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
SVAEEVSDIHMPNNSLIPFFMSLGLFIAGLGAIFQMDNTVVGWSLIGFGLAMTFVSMFLR
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
SWIDDHGYYIPKSQVEADLKAIREKGEQ
HHHHCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AQTTAMQQSRKYNGIMDWITTVDHKKIGILYLFSGIFFLLLGGIEALLIRWQLVKPMND
CCCHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH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HHHHCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1847686; 9384377 [H]