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The map label for this gene is ctaC [H]

Identifier: 229918522

GI number: 229918522

Start: 2777405

End: 2778421

Strand: Direct

Name: ctaC [H]

Synonym: EAT1b_2809

Alternate gene names: 229918522

Gene position: 2777405-2778421 (Clockwise)

Preceding gene: 229918521

Following gene: 229918523

Centisome position: 92.58

GC content: 46.8

Gene sequence:

>1017_bases
GTGAAATCATTTAAGAAGCTTCTGTTTGGCATCGTCCCGATGATGATGTTCGCAGTCCTGTTATCAGGTTGCGGTCAAGA
GGGATTGTCTGCATTGAAGCCGATGGGAGAAGGGGCTGAGCTTCAGCTCCGCATCATTCTCATCAGTTTGGCGATCATGC
TCTTCGTACTCATCATCGTCTCGGTCATTTACGTGTACGTGCTCATGAAGTTCCGTCGGAAAGATGAATCGATTCCGAAG
CAAGTTGAAGGTAGCAGTACACTCGAGATGATTTGGACAGTCGTTCCGATTATCCTTCTCATCATTCTCGCTGTTCCGAC
AATCACGACGACTGTCGAACTCGCGAAAGCGAAAGAAGCGAAAAAAGAAGAAGAAATCAACGTTACAGCTAACTTGTACT
GGTGGGAATTTGAATATCCAGAAGCAGGTGTTGTGACAGGGCAAGAACTCGTCATTCCGGTCGGAAAACGAGTCGGCATC
AACTTGACGTCTAAAGATGTCATTCACTCATTCTGGGTACCAGCTTTATCTGGTAAGACAGATACGAACCCAGGACTTGA
TAACGAAATGTGGTTACATGCAAATGAACCAGGTACTTACTACGGGAAATGTGCTGAGCTTTGCGGTCCGTCACATGCCC
TTATGGACTTTAAAGTCATCGCGCTCGAGCAAGAAGAATATGATCAATGGCTCGCTGACATGAAAGCCAAGCAAGACGAG
AACGGTGAGAAACTCGTCGCAGACAACACGAACTTGACGACAGGTGAGCAAGTGTATGTCGAAAGCTGCTTGAGCTGTCA
CGGCGGCGGTAAAGTGGCACCAAGTTTAACGAACTTCGGTGATCGTGAATGGCTCGCAGGTTACCTCGAAAACAACGAGG
ACAACTTGAAAGAGTGGATTCGTGACCCGCAAGAGAAGAAACAAGGGGCTCTTATGCCAGGATTCAATGAAGGTCAAATC
AGCAACGAAGAATTAGATGCACTCGTTGACTTCTTGTATGAGCAGAAGATTGACTAA

Upstream 100 bases:

>100_bases
GTCGTGTGGATTATCGCGCTGATTTTGACAGCACTCTGGTGATCGCACTCACTATATAGAAAACCATTACACATCATTTT
GGGAGAAAGTGGGGATTGTT

Downstream 100 bases:

>100_bases
CGGGAAAAGGGGGATTTCACGTGGCACAGACCACTGCAATGCAGCAATCGCGTAAATACAATGGCATCATGGATTGGATT
ACGACGGTTGACCACAAAAA

Product: cytochrome c oxidase, subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKSFKKLLFGIVPMMMFAVLLSGCGQEGLSALKPMGEGAELQLRIILISLAIMLFVLIIVSVIYVYVLMKFRRKDESIPK
QVEGSSTLEMIWTVVPIILLIILAVPTITTTVELAKAKEAKKEEEINVTANLYWWEFEYPEAGVVTGQELVIPVGKRVGI
NLTSKDVIHSFWVPALSGKTDTNPGLDNEMWLHANEPGTYYGKCAELCGPSHALMDFKVIALEQEEYDQWLADMKAKQDE
NGEKLVADNTNLTTGEQVYVESCLSCHGGGKVAPSLTNFGDREWLAGYLENNEDNLKEWIRDPQEKKQGALMPGFNEGQI
SNEELDALVDFLYEQKID

Sequences:

>Translated_338_residues
MKSFKKLLFGIVPMMMFAVLLSGCGQEGLSALKPMGEGAELQLRIILISLAIMLFVLIIVSVIYVYVLMKFRRKDESIPK
QVEGSSTLEMIWTVVPIILLIILAVPTITTTVELAKAKEAKKEEEINVTANLYWWEFEYPEAGVVTGQELVIPVGKRVGI
NLTSKDVIHSFWVPALSGKTDTNPGLDNEMWLHANEPGTYYGKCAELCGPSHALMDFKVIALEQEEYDQWLADMKAKQDE
NGEKLVADNTNLTTGEQVYVESCLSCHGGGKVAPSLTNFGDREWLAGYLENNEDNLKEWIRDPQEKKQGALMPGFNEGQI
SNEELDALVDFLYEQKID
>Mature_338_residues
MKSFKKLLFGIVPMMMFAVLLSGCGQEGLSALKPMGEGAELQLRIILISLAIMLFVLIIVSVIYVYVLMKFRRKDESIPK
QVEGSSTLEMIWTVVPIILLIILAVPTITTTVELAKAKEAKKEEEINVTANLYWWEFEYPEAGVVTGQELVIPVGKRVGI
NLTSKDVIHSFWVPALSGKTDTNPGLDNEMWLHANEPGTYYGKCAELCGPSHALMDFKVIALEQEEYDQWLADMKAKQDE
NGEKLVADNTNLTTGEQVYVESCLSCHGGGKVAPSLTNFGDREWLAGYLENNEDNLKEWIRDPQEKKQGALMPGFNEGQI
SNEELDALVDFLYEQKID

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=156, Percent_Identity=28.2051282051282, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1786635, Length=247, Percent_Identity=34.412955465587, Blast_Score=120, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6226540, Length=209, Percent_Identity=27.2727272727273, Blast_Score=90, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR009056
- InterPro:   IPR003088
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM; PF00034 Cytochrom_C [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 37787; Mature: 37787

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSFKKLLFGIVPMMMFAVLLSGCGQEGLSALKPMGEGAELQLRIILISLAIMLFVLIIV
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHH
SVIYVYVLMKFRRKDESIPKQVEGSSTLEMIWTVVPIILLIILAVPTITTTVELAKAKEA
HHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKEEEINVTANLYWWEFEYPEAGVVTGQELVIPVGKRVGINLTSKDVIHSFWVPALSGKT
HHHCCEEEEEEEEEEEEECCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCC
DTNPGLDNEMWLHANEPGTYYGKCAELCGPSHALMDFKVIALEQEEYDQWLADMKAKQDE
CCCCCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHEEEEEEECHHHHHHHHHHHHHCCCC
NGEKLVADNTNLTTGEQVYVESCLSCHGGGKVAPSLTNFGDREWLAGYLENNEDNLKEWI
CCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCHHCCCCHHHHHHHHCCCHHHHHHHH
RDPQEKKQGALMPGFNEGQISNEELDALVDFLYEQKID
CCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKSFKKLLFGIVPMMMFAVLLSGCGQEGLSALKPMGEGAELQLRIILISLAIMLFVLIIV
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHH
SVIYVYVLMKFRRKDESIPKQVEGSSTLEMIWTVVPIILLIILAVPTITTTVELAKAKEA
HHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKEEEINVTANLYWWEFEYPEAGVVTGQELVIPVGKRVGINLTSKDVIHSFWVPALSGKT
HHHCCEEEEEEEEEEEEECCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCC
DTNPGLDNEMWLHANEPGTYYGKCAELCGPSHALMDFKVIALEQEEYDQWLADMKAKQDE
CCCCCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHEEEEEEECHHHHHHHHHHHHHCCCC
NGEKLVADNTNLTTGEQVYVESCLSCHGGGKVAPSLTNFGDREWLAGYLENNEDNLKEWI
CCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCHHCCCCHHHHHHHHCCCHHHHHHHH
RDPQEKKQGALMPGFNEGQISNEELDALVDFLYEQKID
CCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7678007 [H]