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The map label for this gene is cbaA [H]

Identifier: 229918062

GI number: 229918062

Start: 2295780

End: 2297465

Strand: Direct

Name: cbaA [H]

Synonym: EAT1b_2341

Alternate gene names: 229918062

Gene position: 2295780-2297465 (Clockwise)

Preceding gene: 229918061

Following gene: 229918063

Centisome position: 76.53

GC content: 50.89

Gene sequence:

>1686_bases
ATGAATGACGTATCATCTAAACTGAAGCAATGGGAGATGGAACGCGGCGTACCGGTTCCGAGTATCGGAGCCAAAGAGGC
ACGTCTTGCCTACGGACACGTTCTCGTATCCGTTCTCGCCATCTTGATTGGGGCGCTAGCTGGATTGACTCAGACGTTGA
TTCGGACGGGTGTCATTCCTGAAATCTTTGGATACTACCAACTTCTGACTGCGCACGGGATCATGCTCGGAATCGTCTTT
ACGACGATGTTCATTATCGGTCTTTTATATGCGTTACTCGCGAAATCGTTCGGTCGCTTTGAATCATTCCCGACGCGTGT
CGCGTGGCTCGGTTTTTGGACGATGATCATCGGTGCTGTCATGGTAACCGTCATGATTTTGGCCAATAAAGGAACGGTCT
TATATACGTTTTATGCGCCGCTCATGGCAGATCCGCTCTTCTATGTCGGACTCGTGTTATTTGTAGTCGGGACATGGTTG
TCGTCATTCGCGATGTTCCGCATGTATGCGGATTACAAGCGTGACAACCCTGGTGTTCATCCACCACTTCCGGCTTATAT
GAGTATCATGACGATGCTTCTTTGGGACATTGCGACACTTGGTGTCGCAGCCACGATTTTATTCCAGCTCCTTCCGCTCT
CGTTAGGATGGACGGATACAGTCGGAATCGAGTTATCTCGTACATTGTTCTGGTACTTCGGTCACCCGCTCGTTTATTTC
TGGCTCATGCCGGCATACATCGTGTGGTATACGGTCGTACCGAAAGTGATCGGTGGGAAAATCTTCTCGGATGCGTTGGC
GCGGATGGCGTTCTTGCTGTTCTTACTCTTCTCATTCCCGGTCGGTTTCCACCATCAGTTGACAGAGCCAGGGATTGAAC
CGTTCTGGAAGTTCGTTCAAGTCATCTTGACGTTCTTGGTCGTCATCCCTTCATTCATGACTGCATTCTCGCTCTTTGCG
ACGTTTGAACTTCGTGGACGTGCGCTCGGCGCGAAAGGGCTGTTCGGTTGGGTGAAGAAAATGCCGTATGGCGATGTTCG
CTTCCTTGCTCCTTTCGTTGGGATGTTGTTCTTCATCCCGGCCGGTGCAGGTGGAATCATCAACGCTTCGCACCAATTGA
ACGCGATGGTCCACAATACGCTTTGGGTCACAGGACACTTCCACATCACAGTCGGAACTGCCGTCGCCTTAACCTTCTTC
GGAACAGCGTACTGGCTCGTCCCAGTCCTACGCGGTCGCACGTTGACGAAGGCGATGAACAAGCTTGGATTGATTCAAGC
AGGAACATGGGCGTTCGGTATGGCGATCATGTCCTATGCAATGCATATCTCAGGATTGAACGGGAACCCACGTCGTACGG
GTCCGGCAACTTATTTCTCAGATGCATTGACGCGTGAGTGGATCCCATATCATGTCATGATGGCAATCGGGGGAACGATT
TTGTTCATCTCCGTGCTCATCTTTGTCTACTCGATGTTCAACTTGTCATTCCTCGCTCCAAAAGGCGAAGAGGAATTCCC
GCTCGCCGAGACAGAAGAGGCGGCGATGGATACACCGCGCTATTTCGAAAACTGGAAATTGTGGATTACTGTGACGTTCG
TCTTAATCGCATTTGCATACACCGTTCCAATCTGGCACTTGATTGAGAGTGCGCCTCCAGGAGCGCGTGGTTGGGTACTC
TGGTAA

Upstream 100 bases:

>100_bases
ATACACATTCGAGGAAGCTGGCGAATTTTTAATCTTATGTAACGAATATTGTGGTACAGGGCATCACATGATGTCGACTA
AAATCAAGGTGGTGGAATAA

Downstream 100 bases:

>100_bases
ACTGAAGTCAGCTCATTCGTGAGCTGACTTCTTTTGTGTGAGGAGGAACGATATGGACATAGTAGACGTCATCCGTGCGG
CGAGTTCGATGCACTCAGAG

Product: cytochrome c oxidase subunit I

Products: NA

Alternate protein names: Cytochrome c ba(3) subunit I; Cytochrome c oxidase polypeptide I; Cytochrome cba3 subunit 1 [H]

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:

>561_residues
MNDVSSKLKQWEMERGVPVPSIGAKEARLAYGHVLVSVLAILIGALAGLTQTLIRTGVIPEIFGYYQLLTAHGIMLGIVF
TTMFIIGLLYALLAKSFGRFESFPTRVAWLGFWTMIIGAVMVTVMILANKGTVLYTFYAPLMADPLFYVGLVLFVVGTWL
SSFAMFRMYADYKRDNPGVHPPLPAYMSIMTMLLWDIATLGVAATILFQLLPLSLGWTDTVGIELSRTLFWYFGHPLVYF
WLMPAYIVWYTVVPKVIGGKIFSDALARMAFLLFLLFSFPVGFHHQLTEPGIEPFWKFVQVILTFLVVIPSFMTAFSLFA
TFELRGRALGAKGLFGWVKKMPYGDVRFLAPFVGMLFFIPAGAGGIINASHQLNAMVHNTLWVTGHFHITVGTAVALTFF
GTAYWLVPVLRGRTLTKAMNKLGLIQAGTWAFGMAIMSYAMHISGLNGNPRRTGPATYFSDALTREWIPYHVMMAIGGTI
LFISVLIFVYSMFNLSFLAPKGEEEFPLAETEEAAMDTPRYFENWKLWITVTFVLIAFAYTVPIWHLIESAPPGARGWVL
W

Sequences:

>Translated_561_residues
MNDVSSKLKQWEMERGVPVPSIGAKEARLAYGHVLVSVLAILIGALAGLTQTLIRTGVIPEIFGYYQLLTAHGIMLGIVF
TTMFIIGLLYALLAKSFGRFESFPTRVAWLGFWTMIIGAVMVTVMILANKGTVLYTFYAPLMADPLFYVGLVLFVVGTWL
SSFAMFRMYADYKRDNPGVHPPLPAYMSIMTMLLWDIATLGVAATILFQLLPLSLGWTDTVGIELSRTLFWYFGHPLVYF
WLMPAYIVWYTVVPKVIGGKIFSDALARMAFLLFLLFSFPVGFHHQLTEPGIEPFWKFVQVILTFLVVIPSFMTAFSLFA
TFELRGRALGAKGLFGWVKKMPYGDVRFLAPFVGMLFFIPAGAGGIINASHQLNAMVHNTLWVTGHFHITVGTAVALTFF
GTAYWLVPVLRGRTLTKAMNKLGLIQAGTWAFGMAIMSYAMHISGLNGNPRRTGPATYFSDALTREWIPYHVMMAIGGTI
LFISVLIFVYSMFNLSFLAPKGEEEFPLAETEEAAMDTPRYFENWKLWITVTFVLIAFAYTVPIWHLIESAPPGARGWVL
W
>Mature_561_residues
MNDVSSKLKQWEMERGVPVPSIGAKEARLAYGHVLVSVLAILIGALAGLTQTLIRTGVIPEIFGYYQLLTAHGIMLGIVF
TTMFIIGLLYALLAKSFGRFESFPTRVAWLGFWTMIIGAVMVTVMILANKGTVLYTFYAPLMADPLFYVGLVLFVVGTWL
SSFAMFRMYADYKRDNPGVHPPLPAYMSIMTMLLWDIATLGVAATILFQLLPLSLGWTDTVGIELSRTLFWYFGHPLVYF
WLMPAYIVWYTVVPKVIGGKIFSDALARMAFLLFLLFSFPVGFHHQLTEPGIEPFWKFVQVILTFLVVIPSFMTAFSLFA
TFELRGRALGAKGLFGWVKKMPYGDVRFLAPFVGMLFFIPAGAGGIINASHQLNAMVHNTLWVTGHFHITVGTAVALTFF
GTAYWLVPVLRGRTLTKAMNKLGLIQAGTWAFGMAIMSYAMHISGLNGNPRRTGPATYFSDALTREWIPYHVMMAIGGTI
LFISVLIFVYSMFNLSFLAPKGEEEFPLAETEEAAMDTPRYFENWKLWITVTFVLIAFAYTVPIWHLIESAPPGARGWVL
W

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. This Ubiquinol Oxidase Shows Proton Pump Activity Across The Membrane In Addition To The Electron T

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6226519, Length=279, Percent_Identity=25.4480286738351, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 62780; Mature: 62780

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7657607; 10338009; 10775261 [H]