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The map label for this gene is dapH

Identifier: 229917985

GI number: 229917985

Start: 2218066

End: 2218773

Strand: Direct

Name: dapH

Synonym: EAT1b_2264

Alternate gene names: 229917985

Gene position: 2218066-2218773 (Clockwise)

Preceding gene: 229917984

Following gene: 229917986

Centisome position: 73.94

GC content: 52.26

Gene sequence:

>708_bases
ATGTTACTCACAAACGCTTATGAAATCGCACAATATATTAAAGATGCTAAGAAGGAAACACCAGTCAAGCTTTACGTCAA
CGGTCAATTGGCAGGTCTTGAAATCGAGGAAGCGAAAGCATTCGGAACGGATGAGTCGAAACTGTTCTTGACGACGGCAG
AACGCGCTGCGGCATTTTTGGAAGCCAATGCATCGGTCATCACGGATTCACATCTTGAATACGACCGTCGCAACAGTGCC
GTACCGATGCTTGATACGACACGACTCAATGCCCGAATCGAACCAGGCTCGTTCATCCGAGACCACGTCCAAATCGGAAA
CAACGCGGTTGTCATGATGGGAGCTGTCGTCAACATCGGAGCGGTCATCGGAGATGGTTCGATGGTCGACATGAACGCTG
TCATCGGAGCGCGCGGAACGCTCGGGAAAAACGTTCACCTCGGTGCGGGTGCCGTGGTCGCGGGTGTCCTTGAGCCACCT
TCAAAAGATCCGGTCATCATCGAGGACGGTGTCATGATCGGGGCGAACGCGGTCATCTTAGAGGGCGTTCGCGTCGGTGA
AAATGCGGTTGTCGCGGCAGGCAGTGTCGTCACACAAGACGTCCCTCCAGGCGTCGTCGTTGCGGGAACACCGGCACGAA
TCATCAAACAGAAAGATGAAAAAACTTCTGAAAAAACGCAACTTGTTGATGACTTACGCTCTCTCTAA

Upstream 100 bases:

>100_bases
AAACGCGTCTTTGCAAACGGGGCCCTTGCCGCTGCGGCAACGATCATCGATCGCCCGGCAGGACTTTATAATCTATCGAA
CTTATACGAGGAGGCTACTC

Downstream 100 bases:

>100_bases
CGTATAATAGACAGAAAATATAAAAAATGAGGAATGGGAGAGTTGCATTATGGAACAGTATGGACAATGGATGTGGAAAG
ATGGGGCTTGGATTGAGCCG

Product: Tetrahydrodipicolinate succinyltransferase domain protein

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-acetyltransferase; THP acetyltransferase; Tetrahydropicolinate acetylase

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MLLTNAYEIAQYIKDAKKETPVKLYVNGQLAGLEIEEAKAFGTDESKLFLTTAERAAAFLEANASVITDSHLEYDRRNSA
VPMLDTTRLNARIEPGSFIRDHVQIGNNAVVMMGAVVNIGAVIGDGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLEPP
SKDPVIIEDGVMIGANAVILEGVRVGENAVVAAGSVVTQDVPPGVVVAGTPARIIKQKDEKTSEKTQLVDDLRSL

Sequences:

>Translated_235_residues
MLLTNAYEIAQYIKDAKKETPVKLYVNGQLAGLEIEEAKAFGTDESKLFLTTAERAAAFLEANASVITDSHLEYDRRNSA
VPMLDTTRLNARIEPGSFIRDHVQIGNNAVVMMGAVVNIGAVIGDGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLEPP
SKDPVIIEDGVMIGANAVILEGVRVGENAVVAAGSVVTQDVPPGVVVAGTPARIIKQKDEKTSEKTQLVDDLRSL
>Mature_235_residues
MLLTNAYEIAQYIKDAKKETPVKLYVNGQLAGLEIEEAKAFGTDESKLFLTTAERAAAFLEANASVITDSHLEYDRRNSA
VPMLDTTRLNARIEPGSFIRDHVQIGNNAVVMMGAVVNIGAVIGDGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLEPP
SKDPVIIEDGVMIGANAVILEGVRVGENAVVAAGSVVTQDVPPGVVVAGTPARIIKQKDEKTSEKTQLVDDLRSL

Specific function: Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. DapH subfamily

Homologues:

Organism=Escherichia coli, GI1786362, Length=194, Percent_Identity=34.020618556701, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1786537, Length=166, Percent_Identity=29.5180722891566, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786664, Length=54, Percent_Identity=61.1111111111111, Blast_Score=63, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322243, Length=118, Percent_Identity=36.4406779661017, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPH_EXISA (C4L2D4)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002886631.1
- ProteinModelPortal:   C4L2D4
- GeneID:   7870851
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_2264
- OMA:   KNAVIMM
- ProtClustDB:   CLSK2488981
- HAMAP:   MF_01691
- InterPro:   IPR013710
- InterPro:   IPR018357
- InterPro:   IPR019873
- InterPro:   IPR011004
- TIGRFAMs:   TIGR03532

Pfam domain/function: PF08503 DapD_N; SSF51161 Trimer_LpxA_like

EC number: =2.3.1.89

Molecular weight: Translated: 24702; Mature: 24702

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLTNAYEIAQYIKDAKKETPVKLYVNGQLAGLEIEEAKAFGTDESKLFLTTAERAAAFL
CEECCHHHHHHHHHHHHCCCCEEEEECCEEECEEEHHHHHCCCCCCEEEEEEHHHHHHHH
EANASVITDSHLEYDRRNSAVPMLDTTRLNARIEPGSFIRDHVQIGNNAVVMMGAVVNIG
HCCCEEEECCCCCCCCCCCCCCEEECCEEEEEECCCHHHHHHHHCCCCEEEEEEHHEEEE
AVIGDGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLEPPSKDPVIIEDGVMIGANAVIL
EEECCCCEEEEHEEEECCCCCCCEEEECCCCEEEEECCCCCCCCEEEECCEEECCCEEEE
EGVRVGENAVVAAGSVVTQDVPPGVVVAGTPARIIKQKDEKTSEKTQLVDDLRSL
ECEEECCCEEEEECCEEECCCCCCEEEECCCHHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLLTNAYEIAQYIKDAKKETPVKLYVNGQLAGLEIEEAKAFGTDESKLFLTTAERAAAFL
CEECCHHHHHHHHHHHHCCCCEEEEECCEEECEEEHHHHHCCCCCCEEEEEEHHHHHHHH
EANASVITDSHLEYDRRNSAVPMLDTTRLNARIEPGSFIRDHVQIGNNAVVMMGAVVNIG
HCCCEEEECCCCCCCCCCCCCCEEECCEEEEEECCCHHHHHHHHCCCCEEEEEEHHEEEE
AVIGDGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLEPPSKDPVIIEDGVMIGANAVIL
EEECCCCEEEEHEEEECCCCCCCEEEECCCCEEEEECCCCCCCCEEEECCEEECCCEEEE
EGVRVGENAVVAAGSVVTQDVPPGVVVAGTPARIIKQKDEKTSEKTQLVDDLRSL
ECEEECCCEEEEECCEEECCCCCCEEEECCCHHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA