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The map label for this gene is dapB

Identifier: 229917984

GI number: 229917984

Start: 2217339

End: 2218088

Strand: Direct

Name: dapB

Synonym: EAT1b_2263

Alternate gene names: 229917984

Gene position: 2217339-2218088 (Clockwise)

Preceding gene: 229917983

Following gene: 229917985

Centisome position: 73.91

GC content: 52.93

Gene sequence:

>750_bases
ATGAATGTTCTCATCCATGGGTTTGGCGCAATGGGACGGATTGTCGAAGAGGTCGCTCATGCGCAAGGTGTGAATGTCAC
GGCAATCGTCTCACCGGGAAGTGACGAGCACACGGCGACTCTGAATGAGGTGGACGTACCCGTCGATGTCGTGATCGATT
TTTCGAACCCGGCGTTACTCCCTGATTTACTCGCGTTCGGACGGGAGCGCAATATTCCGCTCGTCATTGCGACGACGGGC
TTCACACCGGAAGAATTGGCCGAGATTGAAACGGCTTCACAAGAGATCCCAATCTTCCAGTCTTACAACACCTCATACGG
GATCGCGCTCTTGAAGCAGTTGCTCGACCAACTCGTCCCACTCACTCTCGGGTATGATATTGAAGTGATTGAGGCACACC
ATCGAAAGAAAGTGGACGCACCAAGCGGCACGGCAGAATTGTTGGCACGTGCCATCGAAGCGAAGCGTGACGTGACACCG
ATTTACGAACGAACGTCACGTCGGGAAGCGCGTGGTGCTGAAGAGTTAGGCATGCATTCCATTCGGGGTGGCACGATTTT
CGGTGAGCATACCGTGCTCTTCGCCGGAGATGATGAAATGATTGAACTGAAACATACCGCGTTATCGAAACGCGTCTTTG
CAAACGGGGCCCTTGCCGCTGCGGCAACGATCATCGATCGCCCGGCAGGACTTTATAATCTATCGAACTTATACGAGGAG
GCTACTCATGTTACTCACAAACGCTTATGA

Upstream 100 bases:

>100_bases
GTTTTGAAGTCGGCGCGCCACGCCTACCGCTCGTTCCGATGAGCGCGACGGCTGAAGCGAAATTACTGTCGGCGATGGAG
CAATTCAATGAGGTGAGACA

Downstream 100 bases:

>100_bases
AATCGCACAATATATTAAAGATGCTAAGAAGGAAACACCAGTCAAGCTTTACGTCAACGGTCAATTGGCAGGTCTTGAAA
TCGAGGAAGCGAAAGCATTC

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MNVLIHGFGAMGRIVEEVAHAQGVNVTAIVSPGSDEHTATLNEVDVPVDVVIDFSNPALLPDLLAFGRERNIPLVIATTG
FTPEELAEIETASQEIPIFQSYNTSYGIALLKQLLDQLVPLTLGYDIEVIEAHHRKKVDAPSGTAELLARAIEAKRDVTP
IYERTSRREARGAEELGMHSIRGGTIFGEHTVLFAGDDEMIELKHTALSKRVFANGALAAAATIIDRPAGLYNLSNLYEE
ATHVTHKRL

Sequences:

>Translated_249_residues
MNVLIHGFGAMGRIVEEVAHAQGVNVTAIVSPGSDEHTATLNEVDVPVDVVIDFSNPALLPDLLAFGRERNIPLVIATTG
FTPEELAEIETASQEIPIFQSYNTSYGIALLKQLLDQLVPLTLGYDIEVIEAHHRKKVDAPSGTAELLARAIEAKRDVTP
IYERTSRREARGAEELGMHSIRGGTIFGEHTVLFAGDDEMIELKHTALSKRVFANGALAAAATIIDRPAGLYNLSNLYEE
ATHVTHKRL
>Mature_249_residues
MNVLIHGFGAMGRIVEEVAHAQGVNVTAIVSPGSDEHTATLNEVDVPVDVVIDFSNPALLPDLLAFGRERNIPLVIATTG
FTPEELAEIETASQEIPIFQSYNTSYGIALLKQLLDQLVPLTLGYDIEVIEAHHRKKVDAPSGTAELLARAIEAKRDVTP
IYERTSRREARGAEELGMHSIRGGTIFGEHTVLFAGDDEMIELKHTALSKRVFANGALAAAATIIDRPAGLYNLSNLYEE
ATHVTHKRL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=206, Percent_Identity=36.4077669902913, Blast_Score=118, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_EXISA (C4L2D3)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002886630.1
- GeneID:   7870850
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_2263
- OMA:   GALKACE
- ProtClustDB:   PRK00048
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 27083; Mature: 27083

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLIHGFGAMGRIVEEVAHAQGVNVTAIVSPGSDEHTATLNEVDVPVDVVIDFSNPALL
CCEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCEECCCCCCCEEEEEECCCCCHH
PDLLAFGRERNIPLVIATTGFTPEELAEIETASQEIPIFQSYNTSYGIALLKQLLDQLVP
HHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCC
LTLGYDIEVIEAHHRKKVDAPSGTAELLARAIEAKRDVTPIYERTSRREARGAEELGMHS
CCCCCCEEEEEHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHCCHH
IRGGTIFGEHTVLFAGDDEMIELKHTALSKRVFANGALAAAATIIDRPAGLYNLSNLYEE
CCCCEEECCEEEEEECCCCEEEHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHH
ATHVTHKRL
HHHHHHCCC
>Mature Secondary Structure
MNVLIHGFGAMGRIVEEVAHAQGVNVTAIVSPGSDEHTATLNEVDVPVDVVIDFSNPALL
CCEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCEECCCCCCCEEEEEECCCCCHH
PDLLAFGRERNIPLVIATTGFTPEELAEIETASQEIPIFQSYNTSYGIALLKQLLDQLVP
HHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCC
LTLGYDIEVIEAHHRKKVDAPSGTAELLARAIEAKRDVTPIYERTSRREARGAEELGMHS
CCCCCCEEEEEHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHCCHH
IRGGTIFGEHTVLFAGDDEMIELKHTALSKRVFANGALAAAATIIDRPAGLYNLSNLYEE
CCCCEEECCEEEEEECCCCEEEHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHH
ATHVTHKRL
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA