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The map label for this gene is ade [C]

Identifier: 229917957

GI number: 229917957

Start: 2185944

End: 2187686

Strand: Direct

Name: ade [C]

Synonym: EAT1b_2236

Alternate gene names: 229917957

Gene position: 2185944-2187686 (Clockwise)

Preceding gene: 229917956

Following gene: 229917958

Centisome position: 72.87

GC content: 51.0

Gene sequence:

>1743_bases
ATGCCAACAAAAAGAACGGCGCGGGCACCGTGGTCTAAAGTGATGATTCGTTCACAACTTGAAGTCGTAGATCGATTGCG
GCCACCTTCGCTCGTCTTACAAAATGCAACGTATTTGAACGTTTACGTAAAACAATGGAGAACCGCGAATATTTGGATTG
AGGGAGATCGCATCGTGTATGTCGGTCCAGACTTACCAGAATCAGCGGTCGAAACGGTCGATGTGACAGGAAAGTATATT
GTACCTGGGTATATCGAGCCTCACGCTCATCCGTTTCAATTATACAATCCGGCGACGTTGTCAAAATATGCAGGAGAGCG
TGGAACGACGACGCTCGTCAATGACAACATGCTGCTTTTTTTACAAGAGAAAGAGCAAGCGTTTGCGCAACTCGATGCGA
TTCAACAATTGCCGACGAGTACGTATTGGTGGGCCCGTCTGGATACGCAAACGGAGTTGGACCGGGAGAGCGTAGCTGTC
GACTCGGAACGCATTCACGAGTGGTTTAACCATCCGGACGTCGTCATGGCAGGTGAATTGACGGCATGGCCGCGCGCCTT
GAAGGGCGATGATGAGATGCTTCAGTGGATGCTTGACGCCGAGACGTGCGGTTTGCCGGTCGAGGGACATTTTCCGGGAG
CGTCGCCGAAGACATTGACTAAAATGGCGTTGATGGGAGTACACAGCGACCATGAGGCGATGACGGCGGAAGAGGCGTTC
AATCGATTGGAACTAGGTTATACGACGACGCTTCGACATTCCTCGATTCGTCCGGACCTTCCGGGGATGATTCGTGACCT
ATTGGCGAATGGACTGACGGCGTTCGACCATCTCATGGTGACGACGGACGGTTCGACACCGGGCTTTTATGAGGACGGCA
TGCAGGATGCGCTCGTCCGCATTTTAATCGAAGCGGGATTACCGGCCATCGAAGCCTACCGGATTGTCTCTCATAACGTG
GCCCGTCACTTTGACCTCGATCACATTTTAGGTGCGATTGCGCCAGGCCGCATCGCGCACTTGAACATTCTAGATGCCAT
CGAGGAACCGCGTCCGACGGCTGTGATTGCGAAAGGGCAATGGATTTATCGTGATGGGGTATCGCTTTTCCCGAACGAAT
TAGTGGAAGCGGTCCTCGATAAGATGCCGTCGACAGACGTTTCAATCGAGCTGACGCCACAAGACCTATCTTTCAGCATG
CCCGTCGGACTCGACATGATCAACTCGGTCATCATGAAACTGTTTAAAATTACGCATGACACGGGTCAAGATGAATTACC
GCGTGATGGAGACGAATCGTTTCTCATGTTGCTTGATAAAGAAGGGAAATGGCGATTGAACACAGTTCTGAAAGGTTTCG
CCCGAGATTTTGGTGGACTTGTCAGTTCGTACTCGATCAGTGGGGACTACTTGATTCTAGGGAAATGCAAACAGGATATG
TTACTGGCGTTCAAACGAATGAACGAGCTCGGAGGTGGGATTGTCCTCGTAGACCAGGGCGAAATCGTTGCCGAGATCCC
GTTACCACTCTGTGGGATGACGTCGACGGAGCCGCTCGAAACGCTCATCGGTCAAGAGAAACAGCTGCGAGACGAGCTCA
TGGCGAGGGGCTATCAGTTCGAAGATCCGATTTATACATTACTATTTTTAGCATCTACCCATTTGCCGTATGTTCGGGCG
ACACCTCTCGGCATTTACGAAGTCATGAAGAAACAAGTACTATTTCCTGCGATTTTGCGATGA

Upstream 100 bases:

>100_bases
CGACCCATTCAGAGAAAAGGTAAACTTGAAACAGGGAAAGAAAACGCTTTCAAAACTATTCTTTTATAGCTTTGAAAGGG
AAAAGGGAGGATTGGGTTCG

Downstream 100 bases:

>100_bases
ATAGTTGAGTCCAAGGCGCCCCTGCTTTAGAATGATAAAGAAGTATGAGTAGAGAGGATGCTTGCGGATGCAACTCGATA
AATTACGAGGTCGAGAGCTT

Product: adenine deaminase

Products: NA

Alternate protein names: Adenase; Adenine aminase [H]

Number of amino acids: Translated: 580; Mature: 579

Protein sequence:

>580_residues
MPTKRTARAPWSKVMIRSQLEVVDRLRPPSLVLQNATYLNVYVKQWRTANIWIEGDRIVYVGPDLPESAVETVDVTGKYI
VPGYIEPHAHPFQLYNPATLSKYAGERGTTTLVNDNMLLFLQEKEQAFAQLDAIQQLPTSTYWWARLDTQTELDRESVAV
DSERIHEWFNHPDVVMAGELTAWPRALKGDDEMLQWMLDAETCGLPVEGHFPGASPKTLTKMALMGVHSDHEAMTAEEAF
NRLELGYTTTLRHSSIRPDLPGMIRDLLANGLTAFDHLMVTTDGSTPGFYEDGMQDALVRILIEAGLPAIEAYRIVSHNV
ARHFDLDHILGAIAPGRIAHLNILDAIEEPRPTAVIAKGQWIYRDGVSLFPNELVEAVLDKMPSTDVSIELTPQDLSFSM
PVGLDMINSVIMKLFKITHDTGQDELPRDGDESFLMLLDKEGKWRLNTVLKGFARDFGGLVSSYSISGDYLILGKCKQDM
LLAFKRMNELGGGIVLVDQGEIVAEIPLPLCGMTSTEPLETLIGQEKQLRDELMARGYQFEDPIYTLLFLASTHLPYVRA
TPLGIYEVMKKQVLFPAILR

Sequences:

>Translated_580_residues
MPTKRTARAPWSKVMIRSQLEVVDRLRPPSLVLQNATYLNVYVKQWRTANIWIEGDRIVYVGPDLPESAVETVDVTGKYI
VPGYIEPHAHPFQLYNPATLSKYAGERGTTTLVNDNMLLFLQEKEQAFAQLDAIQQLPTSTYWWARLDTQTELDRESVAV
DSERIHEWFNHPDVVMAGELTAWPRALKGDDEMLQWMLDAETCGLPVEGHFPGASPKTLTKMALMGVHSDHEAMTAEEAF
NRLELGYTTTLRHSSIRPDLPGMIRDLLANGLTAFDHLMVTTDGSTPGFYEDGMQDALVRILIEAGLPAIEAYRIVSHNV
ARHFDLDHILGAIAPGRIAHLNILDAIEEPRPTAVIAKGQWIYRDGVSLFPNELVEAVLDKMPSTDVSIELTPQDLSFSM
PVGLDMINSVIMKLFKITHDTGQDELPRDGDESFLMLLDKEGKWRLNTVLKGFARDFGGLVSSYSISGDYLILGKCKQDM
LLAFKRMNELGGGIVLVDQGEIVAEIPLPLCGMTSTEPLETLIGQEKQLRDELMARGYQFEDPIYTLLFLASTHLPYVRA
TPLGIYEVMKKQVLFPAILR
>Mature_579_residues
PTKRTARAPWSKVMIRSQLEVVDRLRPPSLVLQNATYLNVYVKQWRTANIWIEGDRIVYVGPDLPESAVETVDVTGKYIV
PGYIEPHAHPFQLYNPATLSKYAGERGTTTLVNDNMLLFLQEKEQAFAQLDAIQQLPTSTYWWARLDTQTELDRESVAVD
SERIHEWFNHPDVVMAGELTAWPRALKGDDEMLQWMLDAETCGLPVEGHFPGASPKTLTKMALMGVHSDHEAMTAEEAFN
RLELGYTTTLRHSSIRPDLPGMIRDLLANGLTAFDHLMVTTDGSTPGFYEDGMQDALVRILIEAGLPAIEAYRIVSHNVA
RHFDLDHILGAIAPGRIAHLNILDAIEEPRPTAVIAKGQWIYRDGVSLFPNELVEAVLDKMPSTDVSIELTPQDLSFSMP
VGLDMINSVIMKLFKITHDTGQDELPRDGDESFLMLLDKEGKWRLNTVLKGFARDFGGLVSSYSISGDYLILGKCKQDML
LAFKRMNELGGGIVLVDQGEIVAEIPLPLCGMTSTEPLETLIGQEKQLRDELMARGYQFEDPIYTLLFLASTHLPYVRAT
PLGIYEVMKKQVLFPAILR

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family [H]

Homologues:

Organism=Escherichia coli, GI1790098, Length=595, Percent_Identity=26.0504201680672, Blast_Score=160, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.2 [H]

Molecular weight: Translated: 65008; Mature: 64876

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTKRTARAPWSKVMIRSQLEVVDRLRPPSLVLQNATYLNVYVKQWRTANIWIEGDRIVY
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHEECCCCEEEEEEECCEEEEEEEECCEEEE
VGPDLPESAVETVDVTGKYIVPGYIEPHAHPFQLYNPATLSKYAGERGTTTLVNDNMLLF
ECCCCCHHHHHEEECCCCEEECCEECCCCCCEEECCCHHHHHHCCCCCCEEEECCCEEEE
LQEKEQAFAQLDAIQQLPTSTYWWARLDTQTELDRESVAVDSERIHEWFNHPDVVMAGEL
EECHHHHHHHHHHHHHCCCCCEEEEEECCHHHCCHHHHHCCHHHHHHHHCCCCEEEECCC
TAWPRALKGDDEMLQWMLDAETCGLPVEGHFPGASPKTLTKMALMGVHSDHEAMTAEEAF
CCCCHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHH
NRLELGYTTTLRHSSIRPDLPGMIRDLLANGLTAFDHLMVTTDGSTPGFYEDGMQDALVR
HHHHCCEEEEEECCCCCCCCHHHHHHHHHCCCHHHHEEEEEECCCCCCCHHCCHHHHHHH
ILIEAGLPAIEAYRIVSHNVARHFDLDHILGAIAPGRIAHLNILDAIEEPRPTAVIAKGQ
HHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEHHHHHHCCCCCCEEEECCC
WIYRDGVSLFPNELVEAVLDKMPSTDVSIELTPQDLSFSMPVGLDMINSVIMKLFKITHD
EEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCC
TGQDELPRDGDESFLMLLDKEGKWRLNTVLKGFARDFGGLVSSYSISGDYLILGKCKQDM
CCCCCCCCCCCCCEEEEEECCCCEEHHHHHHHHHHHHHHHHHCEECCCCEEEEECCCHHH
LLAFKRMNELGGGIVLVDQGEIVAEIPLPLCGMTSTEPLETLIGQEKQLRDELMARGYQF
HHHHHHHHHCCCCEEEEECCCEEEECCCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCCC
EDPIYTLLFLASTHLPYVRATPLGIYEVMKKQVLFPAILR
CCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PTKRTARAPWSKVMIRSQLEVVDRLRPPSLVLQNATYLNVYVKQWRTANIWIEGDRIVY
CCCCCCCCCHHHHHHHHHHHHHHHCCCCHHEECCCCEEEEEEECCEEEEEEEECCEEEE
VGPDLPESAVETVDVTGKYIVPGYIEPHAHPFQLYNPATLSKYAGERGTTTLVNDNMLLF
ECCCCCHHHHHEEECCCCEEECCEECCCCCCEEECCCHHHHHHCCCCCCEEEECCCEEEE
LQEKEQAFAQLDAIQQLPTSTYWWARLDTQTELDRESVAVDSERIHEWFNHPDVVMAGEL
EECHHHHHHHHHHHHHCCCCCEEEEEECCHHHCCHHHHHCCHHHHHHHHCCCCEEEECCC
TAWPRALKGDDEMLQWMLDAETCGLPVEGHFPGASPKTLTKMALMGVHSDHEAMTAEEAF
CCCCHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHH
NRLELGYTTTLRHSSIRPDLPGMIRDLLANGLTAFDHLMVTTDGSTPGFYEDGMQDALVR
HHHHCCEEEEEECCCCCCCCHHHHHHHHHCCCHHHHEEEEEECCCCCCCHHCCHHHHHHH
ILIEAGLPAIEAYRIVSHNVARHFDLDHILGAIAPGRIAHLNILDAIEEPRPTAVIAKGQ
HHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEHHHHHHCCCCCCEEEECCC
WIYRDGVSLFPNELVEAVLDKMPSTDVSIELTPQDLSFSMPVGLDMINSVIMKLFKITHD
EEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCC
TGQDELPRDGDESFLMLLDKEGKWRLNTVLKGFARDFGGLVSSYSISGDYLILGKCKQDM
CCCCCCCCCCCCCEEEEEECCCCEEHHHHHHHHHHHHHHHHHCEECCCCEEEEECCCHHH
LLAFKRMNELGGGIVLVDQGEIVAEIPLPLCGMTSTEPLETLIGQEKQLRDELMARGYQF
HHHHHHHHHCCCCEEEEECCCEEEECCCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCCC
EDPIYTLLFLASTHLPYVRATPLGIYEVMKKQVLFPAILR
CCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]