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The map label for this gene is yciR [C]

Identifier: 229917956

GI number: 229917956

Start: 2183474

End: 2185762

Strand: Direct

Name: yciR [C]

Synonym: EAT1b_2235

Alternate gene names: 229917956

Gene position: 2183474-2185762 (Clockwise)

Preceding gene: 229917955

Following gene: 229917957

Centisome position: 72.79

GC content: 47.92

Gene sequence:

>2289_bases
GTGGTCGGCCTGCGTGTTCAAACAAAATTATTTATTGCGATAGCCGTGAACATCGTACTCTTCATCGGGGTCATTTTATT
CGTCATCAAACCGTATTTTGTAGAGAAAAGTATTGAACAGGACAGGGCGATGACCCGCGATCAAATCGAAAGTGTGTCAG
AAGTGTTCGCCAATCACCGACTTATGCTCGAGCGGATTCTTGTCGATTGGTCAGTTTGGACGAATGCCTATGATTTTGTT
CAAAATCAGAATGAAGCATTCATTGAAAACAACATGGGGGAAGAGACACTCGAAAACTTAGGGGTCGGCGCAATGATTTT
CCTCGACCGTGATCGAAAGGTCGTCTACTCGGAATTTACTCAATTTTATGAATTGGATCGTGAAGAGGACAAAGAGATCT
TCACGAACGACTTGATCCGTTACGTCAACTCGTCAGGAATCAAACAAAGTGCGGTGTACGGCACCGATTTCGGTCCGGTC
GTCTTCATGAGTCACCCGATTGTGAAGAGTGATGGGACAGGAGAACCCGGTGGGACGCTCGTGCTCATTCAGAAAATCGG
TCCAGATTTCATGGCCGCGATGAGTGCTCAAGCAAAAACGAAATTATCGATCAGCCCTCTTTCTCACCAGCAGTTGACGG
TCGATCAAGACAATCAATTTGCCCGTGTCTCGTTACCGCTTCAATCCGTCTATCAAGATGCGAACTGGGAACTCAACTTC
TCGGTGAAGCGAACGTACTATACCAACACGCAGACCATGTTAGAAACGGGGATGATCGGGCTTCTTGTCCTCGGTCTTGG
TCTATTGTTGACACTGTTTTGGACGGTGAATCAAATTGTCACGAAACGATTGATGGGCATCGTCAACCAACTGAAATGGA
TCACGAAAGAACGGAATAGTCGGTTACGGATTCAATTGCATCCGAATCAACAAGACGAAATCGAAGAGATGGCCATCAGC
ATGAACGAGGTGCTCGATGCACTCGAACAGACACAAAAGGAATCGTTGACGCGTGCCTTCCGCGATTCCTTGACCCGTCT
TCCGAACCGCTTGGCAGTCGAAGAGATGTTCGTGAGCTTACCGGACACGACCCGATCGATTGGAGTGATGGGAATCGATC
TCGACAACTTCCGCCGCATCAACGATCAATTTGGTCAGCGTACGGGAGATGCGATGCTGACGTTCTTTGCCTCTCGTTTG
ATGTTTTATAAAGAGGATGGCTTCGTTGCGAGAATCGGAGCGGACGAGTTCATCTTGATTCATCCGGAATGGACGACCGA
GGAGCTCATGATCATTGCCAATCAATTGGTGAAAGATTTGCGCGAATGGGGTTTGAAGCAAGGGATGAACCATTTGACCT
TGAGTATCGGCATCGACGAATTGACTGGACCGACGCATCATTCCTATGAGGTGATGATGGCGCGACTCGATGTCGTCTTA
CACGAAGCCAAAGCATCCGGGAAAGATCAGATTCTTTCCTATCATGAGATTGAAGATGGGAGTCATTACTTGCAGGCGCT
CGAAATGGAACGTGATTTACGTCATGCGCTGCGTCATGATGAGTTCGAACTCTATTACCAACCAATCGTCTCTCCGCAGC
CGTTTCAAGTTAGAGGAGTCGAGGCGTTGATTCGCTGGCACCATCCACAGAAAGGGTTCGTCTCTCCCGGCGTTTTCATT
CCGGTTGCGGAGCAACTCGGGCTCATCTCAGATGTAGGACGCTGGGTGCTTGTGCGCGCCATCACCGAGATTCAAGAGTA
CGCAGAGCAGTTTGATTTATTTTTATCGATCAACGTATCGAAGCGTCAGATTTTAGACGACTCGTTTTTAGAAGCGTTGG
AGGAGACGCTCGCTAAGACAGGATTTCCCCCACACCGGTTGCATGTGGAAATCACAGAGAGTGAGGTCGGTGGGAATGTG
TATGAACTTCAACAGTTCATTCAAGCGTTAAAGACCATCGGGGTCAAAATTTCACTCGATGACTTCGGTGTCGGGACATC
GTCACTGTCATATCTGCAATCCCTACGTCTCGACATCGTTAAAATCGATCAGAATTTCGTGAAAGGGATTCCGGAGAATA
AGTTTGACCGCGCGCTGTTAGAGGGGCTGTATCAAACTTTCCAGACGCTTGGACTCGAGATTGTCACGGAAGGGGTCGAG
CGACCGGAACAGCTTGCGTTCGTATTAGAATATAGTGGTTCGCTCATTCAAGGTTATCATTACAGTAAACCGATTCCGGT
CGATCAATTGCACCTGTACTTACGTAAAACCGTCATGACTCAAATTTGA

Upstream 100 bases:

>100_bases
GATTATTTGAAGGATGGGTCAACCCATCCTTTTTTTCATGCGAAAAAAAGGAAATGCCGATATCCTGTTCTACAATAATA
AAGTAGCTTGAAGAAGGAGG

Downstream 100 bases:

>100_bases
TGTAGGTGACTCTTCATAGGAAGAGTCGCCTTTTTTGTGAAAAATATATGTGAAATTTGTTACAATAGGGAACATAACTT
GCGACCCATTCAGAGAAAAG

Product: diguanylate cyclase/phosphodiesterase with extracellular sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 762; Mature: 762

Protein sequence:

>762_residues
MVGLRVQTKLFIAIAVNIVLFIGVILFVIKPYFVEKSIEQDRAMTRDQIESVSEVFANHRLMLERILVDWSVWTNAYDFV
QNQNEAFIENNMGEETLENLGVGAMIFLDRDRKVVYSEFTQFYELDREEDKEIFTNDLIRYVNSSGIKQSAVYGTDFGPV
VFMSHPIVKSDGTGEPGGTLVLIQKIGPDFMAAMSAQAKTKLSISPLSHQQLTVDQDNQFARVSLPLQSVYQDANWELNF
SVKRTYYTNTQTMLETGMIGLLVLGLGLLLTLFWTVNQIVTKRLMGIVNQLKWITKERNSRLRIQLHPNQQDEIEEMAIS
MNEVLDALEQTQKESLTRAFRDSLTRLPNRLAVEEMFVSLPDTTRSIGVMGIDLDNFRRINDQFGQRTGDAMLTFFASRL
MFYKEDGFVARIGADEFILIHPEWTTEELMIIANQLVKDLREWGLKQGMNHLTLSIGIDELTGPTHHSYEVMMARLDVVL
HEAKASGKDQILSYHEIEDGSHYLQALEMERDLRHALRHDEFELYYQPIVSPQPFQVRGVEALIRWHHPQKGFVSPGVFI
PVAEQLGLISDVGRWVLVRAITEIQEYAEQFDLFLSINVSKRQILDDSFLEALEETLAKTGFPPHRLHVEITESEVGGNV
YELQQFIQALKTIGVKISLDDFGVGTSSLSYLQSLRLDIVKIDQNFVKGIPENKFDRALLEGLYQTFQTLGLEIVTEGVE
RPEQLAFVLEYSGSLIQGYHYSKPIPVDQLHLYLRKTVMTQI

Sequences:

>Translated_762_residues
MVGLRVQTKLFIAIAVNIVLFIGVILFVIKPYFVEKSIEQDRAMTRDQIESVSEVFANHRLMLERILVDWSVWTNAYDFV
QNQNEAFIENNMGEETLENLGVGAMIFLDRDRKVVYSEFTQFYELDREEDKEIFTNDLIRYVNSSGIKQSAVYGTDFGPV
VFMSHPIVKSDGTGEPGGTLVLIQKIGPDFMAAMSAQAKTKLSISPLSHQQLTVDQDNQFARVSLPLQSVYQDANWELNF
SVKRTYYTNTQTMLETGMIGLLVLGLGLLLTLFWTVNQIVTKRLMGIVNQLKWITKERNSRLRIQLHPNQQDEIEEMAIS
MNEVLDALEQTQKESLTRAFRDSLTRLPNRLAVEEMFVSLPDTTRSIGVMGIDLDNFRRINDQFGQRTGDAMLTFFASRL
MFYKEDGFVARIGADEFILIHPEWTTEELMIIANQLVKDLREWGLKQGMNHLTLSIGIDELTGPTHHSYEVMMARLDVVL
HEAKASGKDQILSYHEIEDGSHYLQALEMERDLRHALRHDEFELYYQPIVSPQPFQVRGVEALIRWHHPQKGFVSPGVFI
PVAEQLGLISDVGRWVLVRAITEIQEYAEQFDLFLSINVSKRQILDDSFLEALEETLAKTGFPPHRLHVEITESEVGGNV
YELQQFIQALKTIGVKISLDDFGVGTSSLSYLQSLRLDIVKIDQNFVKGIPENKFDRALLEGLYQTFQTLGLEIVTEGVE
RPEQLAFVLEYSGSLIQGYHYSKPIPVDQLHLYLRKTVMTQI
>Mature_762_residues
MVGLRVQTKLFIAIAVNIVLFIGVILFVIKPYFVEKSIEQDRAMTRDQIESVSEVFANHRLMLERILVDWSVWTNAYDFV
QNQNEAFIENNMGEETLENLGVGAMIFLDRDRKVVYSEFTQFYELDREEDKEIFTNDLIRYVNSSGIKQSAVYGTDFGPV
VFMSHPIVKSDGTGEPGGTLVLIQKIGPDFMAAMSAQAKTKLSISPLSHQQLTVDQDNQFARVSLPLQSVYQDANWELNF
SVKRTYYTNTQTMLETGMIGLLVLGLGLLLTLFWTVNQIVTKRLMGIVNQLKWITKERNSRLRIQLHPNQQDEIEEMAIS
MNEVLDALEQTQKESLTRAFRDSLTRLPNRLAVEEMFVSLPDTTRSIGVMGIDLDNFRRINDQFGQRTGDAMLTFFASRL
MFYKEDGFVARIGADEFILIHPEWTTEELMIIANQLVKDLREWGLKQGMNHLTLSIGIDELTGPTHHSYEVMMARLDVVL
HEAKASGKDQILSYHEIEDGSHYLQALEMERDLRHALRHDEFELYYQPIVSPQPFQVRGVEALIRWHHPQKGFVSPGVFI
PVAEQLGLISDVGRWVLVRAITEIQEYAEQFDLFLSINVSKRQILDDSFLEALEETLAKTGFPPHRLHVEITESEVGGNV
YELQQFIQALKTIGVKISLDDFGVGTSSLSYLQSLRLDIVKIDQNFVKGIPENKFDRALLEGLYQTFQTLGLEIVTEGVE
RPEQLAFVLEYSGSLIQGYHYSKPIPVDQLHLYLRKTVMTQI

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=412, Percent_Identity=31.0679611650485, Blast_Score=214, Evalue=2e-56,
Organism=Escherichia coli, GI87081921, Length=436, Percent_Identity=30.7339449541284, Blast_Score=177, Evalue=3e-45,
Organism=Escherichia coli, GI87081980, Length=242, Percent_Identity=32.2314049586777, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI1788502, Length=268, Percent_Identity=30.9701492537313, Blast_Score=136, Evalue=5e-33,
Organism=Escherichia coli, GI226510982, Length=513, Percent_Identity=24.3664717348928, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI1790496, Length=241, Percent_Identity=30.7053941908714, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI87081845, Length=252, Percent_Identity=32.9365079365079, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI1787055, Length=244, Percent_Identity=31.1475409836066, Blast_Score=121, Evalue=2e-28,
Organism=Escherichia coli, GI1786507, Length=259, Percent_Identity=30.1158301158301, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI87081743, Length=239, Percent_Identity=31.3807531380753, Blast_Score=110, Evalue=5e-25,
Organism=Escherichia coli, GI1788849, Length=299, Percent_Identity=28.4280936454849, Blast_Score=109, Evalue=7e-25,
Organism=Escherichia coli, GI1788381, Length=420, Percent_Identity=21.6666666666667, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1789650, Length=537, Percent_Identity=21.2290502793296, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87082096, Length=418, Percent_Identity=22.9665071770335, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1787802, Length=192, Percent_Identity=29.1666666666667, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI87081977, Length=107, Percent_Identity=34.5794392523364, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787410, Length=224, Percent_Identity=25.4464285714286, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI145693134, Length=217, Percent_Identity=27.1889400921659, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 87170; Mature: 87170

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGLRVQTKLFIAIAVNIVLFIGVILFVIKPYFVEKSIEQDRAMTRDQIESVSEVFANHR
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMLERILVDWSVWTNAYDFVQNQNEAFIENNMGEETLENLGVGAMIFLDRDRKVVYSEFT
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHCCCCEEEEEECCCHHHHHHHH
QFYELDREEDKEIFTNDLIRYVNSSGIKQSAVYGTDFGPVVFMSHPIVKSDGTGEPGGTL
HHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCEECCCCCCCCCCEE
VLIQKIGPDFMAAMSAQAKTKLSISPLSHQQLTVDQDNQFARVSLPLQSVYQDANWELNF
EEEECCCCHHHHHHHHHHCCEEEECCCCCCEEEECCCCCEEEEECCHHHHHCCCCCEEEE
SVKRTYYTNTQTMLETGMIGLLVLGLGLLLTLFWTVNQIVTKRLMGIVNQLKWITKERNS
EEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RLRIQLHPNQQDEIEEMAISMNEVLDALEQTQKESLTRAFRDSLTRLPNRLAVEEMFVSL
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
PDTTRSIGVMGIDLDNFRRINDQFGQRTGDAMLTFFASRLMFYKEDGFVARIGADEFILI
CCCCCCCEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEECCCEEEEECCCCEEEE
HPEWTTEELMIIANQLVKDLREWGLKQGMNHLTLSIGIDELTGPTHHSYEVMMARLDVVL
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHCCCCCCCHHHHHHHHHHHHH
HEAKASGKDQILSYHEIEDGSHYLQALEMERDLRHALRHDEFELYYQPIVSPQPFQVRGV
HHHHCCCHHHHEEHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEHHH
EALIRWHHPQKGFVSPGVFIPVAEQLGLISDVGRWVLVRAITEIQEYAEQFDLFLSINVS
HHHHHHCCCCCCCCCCCCEEECHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCH
KRQILDDSFLEALEETLAKTGFPPHRLHVEITESEVGGNVYELQQFIQALKTIGVKISLD
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEC
DFGVGTSSLSYLQSLRLDIVKIDQNFVKGIPENKFDRALLEGLYQTFQTLGLEIVTEGVE
CCCCCHHHHHHHHHHHHHHEEECHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
RPEQLAFVLEYSGSLIQGYHYSKPIPVDQLHLYLRKTVMTQI
CHHHHEEHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVGLRVQTKLFIAIAVNIVLFIGVILFVIKPYFVEKSIEQDRAMTRDQIESVSEVFANHR
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMLERILVDWSVWTNAYDFVQNQNEAFIENNMGEETLENLGVGAMIFLDRDRKVVYSEFT
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHCCCCEEEEEECCCHHHHHHHH
QFYELDREEDKEIFTNDLIRYVNSSGIKQSAVYGTDFGPVVFMSHPIVKSDGTGEPGGTL
HHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCEECCCCCCCCCCEE
VLIQKIGPDFMAAMSAQAKTKLSISPLSHQQLTVDQDNQFARVSLPLQSVYQDANWELNF
EEEECCCCHHHHHHHHHHCCEEEECCCCCCEEEECCCCCEEEEECCHHHHHCCCCCEEEE
SVKRTYYTNTQTMLETGMIGLLVLGLGLLLTLFWTVNQIVTKRLMGIVNQLKWITKERNS
EEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RLRIQLHPNQQDEIEEMAISMNEVLDALEQTQKESLTRAFRDSLTRLPNRLAVEEMFVSL
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
PDTTRSIGVMGIDLDNFRRINDQFGQRTGDAMLTFFASRLMFYKEDGFVARIGADEFILI
CCCCCCCEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEECCCEEEEECCCCEEEE
HPEWTTEELMIIANQLVKDLREWGLKQGMNHLTLSIGIDELTGPTHHSYEVMMARLDVVL
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHCCCCCCCHHHHHHHHHHHHH
HEAKASGKDQILSYHEIEDGSHYLQALEMERDLRHALRHDEFELYYQPIVSPQPFQVRGV
HHHHCCCHHHHEEHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEHHH
EALIRWHHPQKGFVSPGVFIPVAEQLGLISDVGRWVLVRAITEIQEYAEQFDLFLSINVS
HHHHHHCCCCCCCCCCCCEEECHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCH
KRQILDDSFLEALEETLAKTGFPPHRLHVEITESEVGGNVYELQQFIQALKTIGVKISLD
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEC
DFGVGTSSLSYLQSLRLDIVKIDQNFVKGIPENKFDRALLEGLYQTFQTLGLEIVTEGVE
CCCCCHHHHHHHHHHHHHHEEECHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
RPEQLAFVLEYSGSLIQGYHYSKPIPVDQLHLYLRKTVMTQI
CHHHHEEHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]