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The map label for this gene is bglB [H]

Identifier: 229917905

GI number: 229917905

Start: 2120265

End: 2121617

Strand: Direct

Name: bglB [H]

Synonym: EAT1b_2183

Alternate gene names: 229917905

Gene position: 2120265-2121617 (Clockwise)

Preceding gene: 229917904

Following gene: 229917906

Centisome position: 70.68

GC content: 51.52

Gene sequence:

>1353_bases
ATGCATTTTAAGAAAGACTTCGTATTCGGGACAGCCACGTCCTCGTACCAAATTGAAGGCGCACATAACGAAGGAGGCCG
TACTCCTTCCATCTGGGATATGTTCTGTGACATCGACGGGCGCGTGTTTGAAAAGCATAACGGCGATGTCGCATGTGACC
ACTACCATCGTTACGAAGAAGACATTAAGCACATCAAAAAGCTAGGTGTCGACACGTATCGATTCTCCATCGCGTGGCCA
CGAATCTTCCCTGCCAAGGGAGAGTACAACCCAGAAGGGATGGCGTTCTACAAAAACTTGGCGCTGTGTCTCCGTGAAGA
AGGAATCAAACCAGCCGTCACCATTTATCACTGGGACCTTCCGATGTGGGCTCACGAAGAAGGTGGCTGGGTCAACCGTG
AATCGGTCGACTGGTTCCTCGATTATGCGAAAGTCTGTTTTGAAGAGCTCGATGACATCGTCGACTCTTGGATCACTCAC
AATGAGCCTTGGTGTGCCGGCTTCCTCGGCTATCACGTCGGTGTTCACGCACCGGGTCATCGTGATATGAACGAAGCGGT
GCGCGCCGTGCACCATATCTTGTTGTCGCACGGAAAAGCGGTCGAGTTGTTGAAGCGAGAGATGACGTCCACGACCCCGA
TCGGCATCACGCTCAACTTATCACCGATGTACGCGAAGACGGATTCGGCGAATGACCGCCTTGCGATGAACAATGCCGAC
GGGTATTCGAATCGCTGGTTCCTCGATCCGGTCTTCAAAGGTGAGTATCCGGTCGACATGATGAACTTGTTCTCCAAATA
TGTGCATAACTTTGATTTCATCCAACCGGGTGATATGGAGACAATCTCGACAGCTTGCGATTTCTTCGGTATCAATTTCT
ACAGCCGTGGCATTGTCGAGTTTAACGCAGCAAATGATTTCTTGAAGGCAGACGCTTACTCGGACTACGAGAAGACGGGC
ATGGGTTGGGATATCGCCCCGAACGAATTCAAAGACCTGATCCGTCGTTTACGCGCCGAGTATACTGACCTTCCGATCTA
CATCACAGAGAACGGCGCCGCATTTGACGACGTGCTGGAAAATGGCGAAGTCCATGACGATAACCGGATCGACTACGTCC
GCCAGCACCTCGAAGCCGTCTCCGATTTGAACGATGAGGGCATGAACATTCAAGGCTACTACCTCTGGTCGCTCATGGAT
AACTTCGAATGGAGCTTCGGATATGAGAAGCGTTTTGGCATCCTCTATATCGACTTTGAGACACAGGAGCGCATCTGGAA
AGACAGCGCGAAGTGGTATGCCGGTGTCATCGCCGACCATAAAGCCAAACACGCGGATAGCGTCGAGGCGTAA

Upstream 100 bases:

>100_bases
ACCGATTATGATTGCCTTCTTGTTCCTCTCGAAGTACATCGTCAGCAGTATTTCGGCAGGTGCTGTCAAAGAATAAATAT
AGAGAAAAGAGGAAAACACT

Downstream 100 bases:

>100_bases
TATGCATCCATCCCCACCGCTACGGGGATGGATTTTTTGTGTGGAATGCTATCTTTTTGGGAACGAGGATAGGGGAGGGA
TGTTCTATGAAACGCGAGTT

Product: beta-galactosidase

Products: NA

Alternate protein names: Amygdalase; Beta-D-glucoside glucohydrolase; Cellobiase; Gentiobiase [H]

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MHFKKDFVFGTATSSYQIEGAHNEGGRTPSIWDMFCDIDGRVFEKHNGDVACDHYHRYEEDIKHIKKLGVDTYRFSIAWP
RIFPAKGEYNPEGMAFYKNLALCLREEGIKPAVTIYHWDLPMWAHEEGGWVNRESVDWFLDYAKVCFEELDDIVDSWITH
NEPWCAGFLGYHVGVHAPGHRDMNEAVRAVHHILLSHGKAVELLKREMTSTTPIGITLNLSPMYAKTDSANDRLAMNNAD
GYSNRWFLDPVFKGEYPVDMMNLFSKYVHNFDFIQPGDMETISTACDFFGINFYSRGIVEFNAANDFLKADAYSDYEKTG
MGWDIAPNEFKDLIRRLRAEYTDLPIYITENGAAFDDVLENGEVHDDNRIDYVRQHLEAVSDLNDEGMNIQGYYLWSLMD
NFEWSFGYEKRFGILYIDFETQERIWKDSAKWYAGVIADHKAKHADSVEA

Sequences:

>Translated_450_residues
MHFKKDFVFGTATSSYQIEGAHNEGGRTPSIWDMFCDIDGRVFEKHNGDVACDHYHRYEEDIKHIKKLGVDTYRFSIAWP
RIFPAKGEYNPEGMAFYKNLALCLREEGIKPAVTIYHWDLPMWAHEEGGWVNRESVDWFLDYAKVCFEELDDIVDSWITH
NEPWCAGFLGYHVGVHAPGHRDMNEAVRAVHHILLSHGKAVELLKREMTSTTPIGITLNLSPMYAKTDSANDRLAMNNAD
GYSNRWFLDPVFKGEYPVDMMNLFSKYVHNFDFIQPGDMETISTACDFFGINFYSRGIVEFNAANDFLKADAYSDYEKTG
MGWDIAPNEFKDLIRRLRAEYTDLPIYITENGAAFDDVLENGEVHDDNRIDYVRQHLEAVSDLNDEGMNIQGYYLWSLMD
NFEWSFGYEKRFGILYIDFETQERIWKDSAKWYAGVIADHKAKHADSVEA
>Mature_450_residues
MHFKKDFVFGTATSSYQIEGAHNEGGRTPSIWDMFCDIDGRVFEKHNGDVACDHYHRYEEDIKHIKKLGVDTYRFSIAWP
RIFPAKGEYNPEGMAFYKNLALCLREEGIKPAVTIYHWDLPMWAHEEGGWVNRESVDWFLDYAKVCFEELDDIVDSWITH
NEPWCAGFLGYHVGVHAPGHRDMNEAVRAVHHILLSHGKAVELLKREMTSTTPIGITLNLSPMYAKTDSANDRLAMNNAD
GYSNRWFLDPVFKGEYPVDMMNLFSKYVHNFDFIQPGDMETISTACDFFGINFYSRGIVEFNAANDFLKADAYSDYEKTG
MGWDIAPNEFKDLIRRLRAEYTDLPIYITENGAAFDDVLENGEVHDDNRIDYVRQHLEAVSDLNDEGMNIQGYYLWSLMD
NFEWSFGYEKRFGILYIDFETQERIWKDSAKWYAGVIADHKAKHADSVEA

Specific function: Unknown

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=467, Percent_Identity=34.475374732334, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI110681710, Length=481, Percent_Identity=31.3929313929314, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI13273313, Length=468, Percent_Identity=30.3418803418803, Blast_Score=215, Evalue=7e-56,
Organism=Homo sapiens, GI28376633, Length=449, Percent_Identity=29.6213808463252, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI24497614, Length=462, Percent_Identity=30.5194805194805, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI190360571, Length=85, Percent_Identity=45.8823529411765, Blast_Score=86, Evalue=5e-17,
Organism=Escherichia coli, GI2367174, Length=485, Percent_Identity=30.1030927835052, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1789070, Length=478, Percent_Identity=29.4979079497908, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI2367270, Length=467, Percent_Identity=32.1199143468951, Blast_Score=189, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI17552856, Length=476, Percent_Identity=34.453781512605, Blast_Score=253, Evalue=1e-67,
Organism=Caenorhabditis elegans, GI17539390, Length=475, Percent_Identity=33.4736842105263, Blast_Score=234, Evalue=6e-62,
Organism=Drosophila melanogaster, GI21356577, Length=454, Percent_Identity=34.1409691629956, Blast_Score=239, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017736
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.21 [H]

Molecular weight: Translated: 52107; Mature: 52107

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFKKDFVFGTATSSYQIEGAHNEGGRTPSIWDMFCDIDGRVFEKHNGDVACDHYHRYEE
CCCCCCEEEEECCCCEEEECCCCCCCCCCCHHHHEECCCCEEEECCCCCEEEHHHHHHHH
DIKHIKKLGVDTYRFSIAWPRIFPAKGEYNPEGMAFYKNLALCLREEGIKPAVTIYHWDL
HHHHHHHCCCCEEEEEEECCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECC
PMWAHEEGGWVNRESVDWFLDYAKVCFEELDDIVDSWITHNEPWCAGFLGYHVGVHAPGH
CCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCEECCCCC
RDMNEAVRAVHHILLSHGKAVELLKREMTSTTPIGITLNLSPMYAKTDSANDRLAMNNAD
CCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEECCCCEECCCCCCCEEEECCCC
GYSNRWFLDPVFKGEYPVDMMNLFSKYVHNFDFIQPGDMETISTACDFFGINFYSRGIVE
CCCCCEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHCCEEE
FNAANDFLKADAYSDYEKTGMGWDIAPNEFKDLIRRLRAEYTDLPIYITENGAAFDDVLE
EECCCCHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHC
NGEVHDDNRIDYVRQHLEAVSDLNDEGMNIQGYYLWSLMDNFEWSFGYEKRFGILYIDFE
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEHHCCCCCCCCCCCEEEEEEEEC
TQERIWKDSAKWYAGVIADHKAKHADSVEA
HHHHHHHHCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MHFKKDFVFGTATSSYQIEGAHNEGGRTPSIWDMFCDIDGRVFEKHNGDVACDHYHRYEE
CCCCCCEEEEECCCCEEEECCCCCCCCCCCHHHHEECCCCEEEECCCCCEEEHHHHHHHH
DIKHIKKLGVDTYRFSIAWPRIFPAKGEYNPEGMAFYKNLALCLREEGIKPAVTIYHWDL
HHHHHHHCCCCEEEEEEECCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECC
PMWAHEEGGWVNRESVDWFLDYAKVCFEELDDIVDSWITHNEPWCAGFLGYHVGVHAPGH
CCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCEECCCCC
RDMNEAVRAVHHILLSHGKAVELLKREMTSTTPIGITLNLSPMYAKTDSANDRLAMNNAD
CCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEECCCCEECCCCCCCEEEECCCC
GYSNRWFLDPVFKGEYPVDMMNLFSKYVHNFDFIQPGDMETISTACDFFGINFYSRGIVE
CCCCCEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHCCEEE
FNAANDFLKADAYSDYEKTGMGWDIAPNEFKDLIRRLRAEYTDLPIYITENGAAFDDVLE
EECCCCHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHC
NGEVHDDNRIDYVRQHLEAVSDLNDEGMNIQGYYLWSLMDNFEWSFGYEKRFGILYIDFE
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEHHCCCCCCCCCCCEEEEEEEEC
TQERIWKDSAKWYAGVIADHKAKHADSVEA
HHHHHHHHCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2123813 [H]