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The map label for this gene is walR [H]

Identifier: 229917735

GI number: 229917735

Start: 1964995

End: 1965687

Strand: Direct

Name: walR [H]

Synonym: EAT1b_2012

Alternate gene names: 229917735

Gene position: 1964995-1965687 (Clockwise)

Preceding gene: 229917732

Following gene: 229917736

Centisome position: 65.5

GC content: 49.49

Gene sequence:

>693_bases
ATGAATCGAATTTTAGTAGCTGAGGATGAACATGCGATTCGCAGCTTCATTATTGTCAATTTAAAACGAGCCGGATTCGA
TGTGTTCGAAGCGACGAACGGCCGAGAAGCGGTCACCGCATTTGACCGTGAACCGTTCGATGTCGTCTTATTGGATGTCA
TGATGCCAGAAATGGACGGATTCGAGGCATGTGCAGCCATTCGTGATCTTGACGAAAATGTAGGGATCATCATGTTGACG
GCACGGACGCTCGAAGAAGATAAAATAGAGGGGCTCGGTAAAGGTGCAGACGATTACATCGCCAAACCGTTCAGTCCAGG
TGAATTGGTGGCACGCATCCAAGCGTTGTTGCGCCGTGTTGAAAAAGTGAAACGAAAAGATTCGAAGCGCTTGAAGTCGG
GACCGTTCGCCATCGATCTCGCCGCAAAACAAGTGACGAAGTATGGACAGTCGATCGATTTGACGCCGACGGAGTATGAC
TTGATCTGTCATCTCGTCCAAAATGAAGAGATCGTCTTGTCACGTGATGCGCTACTCGATGCGGTGTGGGGCGTCAACTA
TTTCGGTGACCGAAAGACAGTCGACGTCAACATTCGTCGCTTGCGACAAAAAATCGAAGATGACCCGAGTCATCCGGTGT
ACATCGAGACGTTGTGGGGTCACGGATATAAATGGCGGAGACATGAGGCATGA

Upstream 100 bases:

>100_bases
TCTAATGACTCCATCCTAAACCTTTTTAAGGTCAATTGACAACCTTGTCGCAAAAACGTAACTATAATGTAGAGAAGTGA
ACTCTAGAAGAGGTGTAAAT

Downstream 100 bases:

>100_bases
AACAACAGTTAGTCATTCGCATGATGATTGTCGTGACGATCGTCTTGCTCTTACTCGTCAGCGTTTTGTCTTACGGGACG
TATCGCTACTATTACGAGTA

Product: two component transcriptional regulator, winged helix family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MNRILVAEDEHAIRSFIIVNLKRAGFDVFEATNGREAVTAFDREPFDVVLLDVMMPEMDGFEACAAIRDLDENVGIIMLT
ARTLEEDKIEGLGKGADDYIAKPFSPGELVARIQALLRRVEKVKRKDSKRLKSGPFAIDLAAKQVTKYGQSIDLTPTEYD
LICHLVQNEEIVLSRDALLDAVWGVNYFGDRKTVDVNIRRLRQKIEDDPSHPVYIETLWGHGYKWRRHEA

Sequences:

>Translated_230_residues
MNRILVAEDEHAIRSFIIVNLKRAGFDVFEATNGREAVTAFDREPFDVVLLDVMMPEMDGFEACAAIRDLDENVGIIMLT
ARTLEEDKIEGLGKGADDYIAKPFSPGELVARIQALLRRVEKVKRKDSKRLKSGPFAIDLAAKQVTKYGQSIDLTPTEYD
LICHLVQNEEIVLSRDALLDAVWGVNYFGDRKTVDVNIRRLRQKIEDDPSHPVYIETLWGHGYKWRRHEA
>Mature_230_residues
MNRILVAEDEHAIRSFIIVNLKRAGFDVFEATNGREAVTAFDREPFDVVLLDVMMPEMDGFEACAAIRDLDENVGIIMLT
ARTLEEDKIEGLGKGADDYIAKPFSPGELVARIQALLRRVEKVKRKDSKRLKSGPFAIDLAAKQVTKYGQSIDLTPTEYD
LICHLVQNEEIVLSRDALLDAVWGVNYFGDRKTVDVNIRRLRQKIEDDPSHPVYIETLWGHGYKWRRHEA

Specific function: Member of the two-component regulatory system walK/walR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=36.8888888888889, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=37.3333333333333, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=39.4736842105263, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=34.9775784753363, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=33.4841628959276, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=32.7354260089686, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=34.9775784753363, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=33.9366515837104, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=33.4841628959276, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=36.4035087719298, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=31.6742081447964, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=29.9559471365639, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=33.0543933054393, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788550, Length=118, Percent_Identity=38.135593220339, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790437, Length=120, Percent_Identity=31.6666666666667, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789149, Length=74, Percent_Identity=39.1891891891892, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI1788713, Length=102, Percent_Identity=33.3333333333333, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI145693157, Length=102, Percent_Identity=33.3333333333333, Blast_Score=61, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=103, Percent_Identity=30.0970873786408, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26200; Mature: 26200

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRILVAEDEHAIRSFIIVNLKRAGFDVFEATNGREAVTAFDREPFDVVLLDVMMPEMDG
CCCEEEECCHHHHHHHHHEEEHHCCCEEEECCCCCCEEEECCCCCHHEEEHHHHCCCCCC
FEACAAIRDLDENVGIIMLTARTLEEDKIEGLGKGADDYIAKPFSPGELVARIQALLRRV
HHHHHHHHHCCCCCCEEEEEECCCCHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHH
EKVKRKDSKRLKSGPFAIDLAAKQVTKYGQSIDLTPTEYDLICHLVQNEEIVLSRDALLD
HHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEEHHHHHH
AVWGVNYFGDRKTVDVNIRRLRQKIEDDPSHPVYIETLWGHGYKWRRHEA
HHHCCCCCCCCEEEEHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MNRILVAEDEHAIRSFIIVNLKRAGFDVFEATNGREAVTAFDREPFDVVLLDVMMPEMDG
CCCEEEECCHHHHHHHHHEEEHHCCCEEEECCCCCCEEEECCCCCHHEEEHHHHCCCCCC
FEACAAIRDLDENVGIIMLTARTLEEDKIEGLGKGADDYIAKPFSPGELVARIQALLRRV
HHHHHHHHHCCCCCCEEEEEECCCCHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHH
EKVKRKDSKRLKSGPFAIDLAAKQVTKYGQSIDLTPTEYDLICHLVQNEEIVLSRDALLD
HHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEEHHHHHH
AVWGVNYFGDRKTVDVNIRRLRQKIEDDPSHPVYIETLWGHGYKWRRHEA
HHHCCCCCCCCEEEEHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA