Click here to switch to the map view.

The map label for this gene is oxaA1 [H]

Identifier: 229917458

GI number: 229917458

Start: 1701993

End: 1702853

Strand: Direct

Name: oxaA1 [H]

Synonym: EAT1b_1733

Alternate gene names: 229917458

Gene position: 1701993-1702853 (Clockwise)

Preceding gene: 229917457

Following gene: 229917459

Centisome position: 56.74

GC content: 47.27

Gene sequence:

>861_bases
ATGAGCAAAAAGCTAAAATTAGGATTACTCGCTGCCATGACCGCGGTCATCATGCTGATGGCAGGCTGTGTGGATCCGTC
TACCATCCAAGCCGAACCAGTAACGGCTGACACAGAAGGTTTCTGGGCGAAGTACTTTGTATGGCCGCTCGCATGGCTTT
TGAAGGAAGTTGCTTACTTGGTCGGTGGCCCGTGGCAATACGGGATTTCAATCATCATCGCGACGATTATCGTCCGGTTA
TTGATTCTCCCACTCATGATCAAGCAGACGAAGAGTATGGGTGCGATGCAAGTGTTGCAACCAGAAATGCTGAAGCTTCG
TGAAAAGTACAGCTCAAAAGACCAGGAAACACAACGTAAACTCCAAGAAGAGATGATGAAGCTTTATCAGGAATACCAAA
TCAACCCGCTCGCGGGATGTTTGCCGATCTTGATTCAAATGCCGATTCTCTTCGCATTCTATGATGCGATTCGCCGTACA
CCTGAGATTTTCGAAGCGAACTTCTTATGGTTCGACCTCGGTGCTCCGGATCCAACGTTCGTCTTGCCGATCTTAGCGGC
AATCTTGACGTTCGCACAACAAAAAATCTCAATGGCGGGTCAAGAACAGAACCCGCAGTTGAAGATGATGCTTTATATCT
TCCCGGTTATGATCTTCGTCATGTCGATCAACCTCCCAGCTGCCCTTTCGTTATACTGGGTAGTCGGTTATATCATCTCG
ATCATCGTCACGATGGCAATCATGCTCCCAATGCGTGAGAAGATGAAGGTTGCGGCTGAAGCGAAAATCGCTGCGAAAGA
AGCAGAGCGTGCAGCGCTTGCTGAAGAAGAAAAGAAAAATAAAAAGAAAAAGCGTAAATAA

Upstream 100 bases:

>100_bases
GACAATCTGAATTTGTTCTCTCATATAATTAGAGTCTGATAAGATTGCCCGATCGACGTGTGCGTTAAAAAGAATTGATA
AAGAAAGCGTAGGAGGAACT

Downstream 100 bases:

>100_bases
TCGCTAAGCTGAGTGTCTTCTGACGCTCAGCTTTTTTGTGGGATTGCAAGCCGGTCAGAGGGGAATAGAGATAGAAACGA
GTAAACGGAGGTGTGGAAAA

Product: 60 kDa inner membrane insertion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MSKKLKLGLLAAMTAVIMLMAGCVDPSTIQAEPVTADTEGFWAKYFVWPLAWLLKEVAYLVGGPWQYGISIIIATIIVRL
LILPLMIKQTKSMGAMQVLQPEMLKLREKYSSKDQETQRKLQEEMMKLYQEYQINPLAGCLPILIQMPILFAFYDAIRRT
PEIFEANFLWFDLGAPDPTFVLPILAAILTFAQQKISMAGQEQNPQLKMMLYIFPVMIFVMSINLPAALSLYWVVGYIIS
IIVTMAIMLPMREKMKVAAEAKIAAKEAERAALAEEEKKNKKKKRK

Sequences:

>Translated_286_residues
MSKKLKLGLLAAMTAVIMLMAGCVDPSTIQAEPVTADTEGFWAKYFVWPLAWLLKEVAYLVGGPWQYGISIIIATIIVRL
LILPLMIKQTKSMGAMQVLQPEMLKLREKYSSKDQETQRKLQEEMMKLYQEYQINPLAGCLPILIQMPILFAFYDAIRRT
PEIFEANFLWFDLGAPDPTFVLPILAAILTFAQQKISMAGQEQNPQLKMMLYIFPVMIFVMSINLPAALSLYWVVGYIIS
IIVTMAIMLPMREKMKVAAEAKIAAKEAERAALAEEEKKNKKKKRK
>Mature_285_residues
SKKLKLGLLAAMTAVIMLMAGCVDPSTIQAEPVTADTEGFWAKYFVWPLAWLLKEVAYLVGGPWQYGISIIIATIIVRLL
ILPLMIKQTKSMGAMQVLQPEMLKLREKYSSKDQETQRKLQEEMMKLYQEYQINPLAGCLPILIQMPILFAFYDAIRRTP
EIFEANFLWFDLGAPDPTFVLPILAAILTFAQQKISMAGQEQNPQLKMMLYIFPVMIFVMSINLPAALSLYWVVGYIISI
IVTMAIMLPMREKMKVAAEAKIAAKEAERAALAEEEKKNKKKKRK

Specific function: Required for the insertion of integral membrane proteins into the membrane. May also be involved in protein secretion processes [H]

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790140, Length=223, Percent_Identity=36.7713004484305, Blast_Score=125, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6321002, Length=261, Percent_Identity=25.6704980842912, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24662345, Length=213, Percent_Identity=28.169014084507, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21356443, Length=213, Percent_Identity=28.169014084507, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001708
- InterPro:   IPR023060 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 32474; Mature: 32343

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
7.0 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
6.7 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKKLKLGLLAAMTAVIMLMAGCVDPSTIQAEPVTADTEGFWAKYFVWPLAWLLKEVAYL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VGGPWQYGISIIIATIIVRLLILPLMIKQTKSMGAMQVLQPEMLKLREKYSSKDQETQRK
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LQEEMMKLYQEYQINPLAGCLPILIQMPILFAFYDAIRRTPEIFEANFLWFDLGAPDPTF
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEEEECCCCCHHH
VLPILAAILTFAQQKISMAGQEQNPQLKMMLYIFPVMIFVMSINLPAALSLYWVVGYIIS
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
IIVTMAIMLPMREKMKVAAEAKIAAKEAERAALAEEEKKNKKKKRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721630 [H]