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The map label for this gene is rnpA

Identifier: 229917457

GI number: 229917457

Start: 1701544

End: 1701888

Strand: Direct

Name: rnpA

Synonym: EAT1b_1732

Alternate gene names: 229917457

Gene position: 1701544-1701888 (Clockwise)

Preceding gene: 229917456

Following gene: 229917458

Centisome position: 56.72

GC content: 49.57

Gene sequence:

>345_bases
TTGAAAAAAGAATACCGCCTGCAAAAGAATGAAGAGTTCCAAGCGGTGTTTCGCGAAGGACGCTCCGTGGCCAATCGTCA
GTTTGTCGTCTACACGCTCAAAGCGGATCAAACGCATTTCAGAGTGGGTCTTTCCGTCAGTAAGAAACTTGGAAATGCTG
TGGAACGGAACCGGATGAAACGATTGATGCGTGAGTCGCTTCGCTTGCTCGAACCAAACGTTGCACCGAATGATTATGTC
ATCATCGCTCGAAAACCTGCGACCGCATTGACGCAGTCGGAAGTGACCGAGAGTTTAAAACACGTATTCAAACGGGCCAA
GGTTTGGCAAAAGCAGGGCCGGTGA

Upstream 100 bases:

>100_bases
ACAGAAACGTAGTATTTCATGGATTCTCCCTCGTTCAAATGATGTGGATATGATATGATGTTAGTTGACGATTTTTGAAG
CGAAGGATGGAGTGAGAATT

Downstream 100 bases:

>100_bases
CCATGACAATCTGAATTTGTTCTCTCATATAATTAGAGTCTGATAAGATTGCCCGATCGACGTGTGCGTTAAAAAGAATT
GATAAAGAAAGCGTAGGAGG

Product: ribonuclease P

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5

Number of amino acids: Translated: 114; Mature: 114

Protein sequence:

>114_residues
MKKEYRLQKNEEFQAVFREGRSVANRQFVVYTLKADQTHFRVGLSVSKKLGNAVERNRMKRLMRESLRLLEPNVAPNDYV
IIARKPATALTQSEVTESLKHVFKRAKVWQKQGR

Sequences:

>Translated_114_residues
MKKEYRLQKNEEFQAVFREGRSVANRQFVVYTLKADQTHFRVGLSVSKKLGNAVERNRMKRLMRESLRLLEPNVAPNDYV
IIARKPATALTQSEVTESLKHVFKRAKVWQKQGR
>Mature_114_residues
MKKEYRLQKNEEFQAVFREGRSVANRQFVVYTLKADQTHFRVGLSVSKKLGNAVERNRMKRLMRESLRLLEPNVAPNDYV
IIARKPATALTQSEVTESLKHVFKRAKVWQKQGR

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family

Homologues:

Organism=Escherichia coli, GI1790139, Length=104, Percent_Identity=33.6538461538462, Blast_Score=59, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNPA_EXISA (C4KZZ5)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002886103.1
- GeneID:   7870779
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_1732
- OMA:   KIGNAVM
- ProtClustDB:   PRK00499
- HAMAP:   MF_00227
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- InterPro:   IPR020539
- Gene3D:   G3DSA:3.30.230.10
- ProDom:   PD003629
- TIGRFAMs:   TIGR00188

Pfam domain/function: PF00825 Ribonuclease_P; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =3.1.26.5

Molecular weight: Translated: 13375; Mature: 13375

Theoretical pI: Translated: 11.34; Mature: 11.34

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEYRLQKNEEFQAVFREGRSVANRQFVVYTLKADQTHFRVGLSVSKKLGNAVERNRMK
CCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHH
RLMRESLRLLEPNVAPNDYVIIARKPATALTQSEVTESLKHVFKRAKVWQKQGR
HHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKEYRLQKNEEFQAVFREGRSVANRQFVVYTLKADQTHFRVGLSVSKKLGNAVERNRMK
CCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHH
RLMRESLRLLEPNVAPNDYVIIARKPATALTQSEVTESLKHVFKRAKVWQKQGR
HHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA