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The map label for this gene is yabD [H]

Identifier: 229917421

GI number: 229917421

Start: 1646717

End: 1647484

Strand: Reverse

Name: yabD [H]

Synonym: EAT1b_1696

Alternate gene names: 229917421

Gene position: 1647484-1646717 (Counterclockwise)

Preceding gene: 229917422

Following gene: 229917420

Centisome position: 54.92

GC content: 49.35

Gene sequence:

>768_bases
ATGTTAATTGATACACATACGCACATCAATGCGGAACAGTTCAGTGAAGACGTGGAGGAGACGATTGAGCGAGCGAGAGA
AGCGGGCGTTTCTCCGCTACTCGTCGTCGGATTTGATACACCGACCATCGATCGAGCCATTGAACTGGCAGAAACGCATG
AAGATATCTATGCCATTGTCGGATGGCATCCAGTCGATGCGATTGACTGTACGGATGCGGATTTAGCACGAATCGAAACA
CTCATGAGTCATCCAAAAGTCATGGCACTCGGTGAAATCGGACTCGATTATCATTGGGACAAATCACCGAAAGACGTGCA
ACAGCGCCTCTTCCGTCAACAAATCGCCATTGCCAAGCGAACGAATATGCCAATTGTCATTCATAACCGAGACGCAACGG
CGGATGTCCTTGATATTTTAGAAGAAGAGCATGCTGAGGAAGTCGGTGGTGTGTTCCATAGTTACAGCATGTCCGTCGAA
CTTTTGCCTCGGTGCCTAGACTTGAACTTCTATATTTCGTTAGGAGGACCGGTCACGTTCAAAAATGCGAAAGTTCCGAA
GGCGGTAGCGCAAGAAGTTCCACTGGATCGTCTGCTTGTCGAGACGGACTGCCCGTACTTGACGCCAACACCGTTCCGTG
GAAAACGAAATGAACCAGCGTACGTCAAATACGTAGCCGAAGAAATCGCCACTCTTCGCGATATGCCTTACGATGAACTC
GCTGCTGCTACGACAGTCAACGCGAAGAAGTTGTTCCGACTCCCATGA

Upstream 100 bases:

>100_bases
GCTCGCGACGGTCTCAGACCAGATGCCGAACGGTGCCATCGTCAAATAATGGAATGGGGGAGACCGCGGTCTCCCTCTCT
TTTTCTAAGGAGGAAACAAG

Downstream 100 bases:

>100_bases
TCAAGCGTGTATTAGCGAGTATCGGTATTATTGCGACGGCTTCTGTGGCGTACGTGATGTTACAACCTGAATCGATTCGA
ATCGTCGATGACGGTGTAGT

Product: hydrolase, TatD family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MLIDTHTHINAEQFSEDVEETIERAREAGVSPLLVVGFDTPTIDRAIELAETHEDIYAIVGWHPVDAIDCTDADLARIET
LMSHPKVMALGEIGLDYHWDKSPKDVQQRLFRQQIAIAKRTNMPIVIHNRDATADVLDILEEEHAEEVGGVFHSYSMSVE
LLPRCLDLNFYISLGGPVTFKNAKVPKAVAQEVPLDRLLVETDCPYLTPTPFRGKRNEPAYVKYVAEEIATLRDMPYDEL
AAATTVNAKKLFRLP

Sequences:

>Translated_255_residues
MLIDTHTHINAEQFSEDVEETIERAREAGVSPLLVVGFDTPTIDRAIELAETHEDIYAIVGWHPVDAIDCTDADLARIET
LMSHPKVMALGEIGLDYHWDKSPKDVQQRLFRQQIAIAKRTNMPIVIHNRDATADVLDILEEEHAEEVGGVFHSYSMSVE
LLPRCLDLNFYISLGGPVTFKNAKVPKAVAQEVPLDRLLVETDCPYLTPTPFRGKRNEPAYVKYVAEEIATLRDMPYDEL
AAATTVNAKKLFRLP
>Mature_255_residues
MLIDTHTHINAEQFSEDVEETIERAREAGVSPLLVVGFDTPTIDRAIELAETHEDIYAIVGWHPVDAIDCTDADLARIET
LMSHPKVMALGEIGLDYHWDKSPKDVQQRLFRQQIAIAKRTNMPIVIHNRDATADVLDILEEEHAEEVGGVFHSYSMSVE
LLPRCLDLNFYISLGGPVTFKNAKVPKAVAQEVPLDRLLVETDCPYLTPTPFRGKRNEPAYVKYVAEEIATLRDMPYDEL
AAATTVNAKKLFRLP

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=270, Percent_Identity=28.8888888888889, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI110349730, Length=264, Percent_Identity=28.4090909090909, Blast_Score=104, Evalue=6e-23,
Organism=Homo sapiens, GI110349734, Length=264, Percent_Identity=27.2727272727273, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI225903439, Length=248, Percent_Identity=28.6290322580645, Blast_Score=101, Evalue=5e-22,
Organism=Homo sapiens, GI226061853, Length=270, Percent_Identity=26.6666666666667, Blast_Score=101, Evalue=6e-22,
Organism=Homo sapiens, GI226061614, Length=256, Percent_Identity=28.515625, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI225903424, Length=205, Percent_Identity=26.8292682926829, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI226061595, Length=227, Percent_Identity=24.6696035242291, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1787342, Length=258, Percent_Identity=40.6976744186046, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI87082439, Length=256, Percent_Identity=33.984375, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI48994985, Length=257, Percent_Identity=31.9066147859922, Blast_Score=132, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17559024, Length=280, Percent_Identity=29.6428571428571, Blast_Score=131, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI71980746, Length=264, Percent_Identity=25.7575757575758, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17543026, Length=188, Percent_Identity=29.7872340425532, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17565396, Length=227, Percent_Identity=28.1938325991189, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24648690, Length=285, Percent_Identity=31.9298245614035, Blast_Score=128, Evalue=5e-30,
Organism=Drosophila melanogaster, GI221330018, Length=277, Percent_Identity=29.9638989169675, Blast_Score=101, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24586117, Length=277, Percent_Identity=29.9638989169675, Blast_Score=101, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.- [C]

Molecular weight: Translated: 28678; Mature: 28678

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS01137 TATD_1 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIDTHTHINAEQFSEDVEETIERAREAGVSPLLVVGFDTPTIDRAIELAETHEDIYAIV
CEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCEEEEE
GWHPVDAIDCTDADLARIETLMSHPKVMALGEIGLDYHWDKSPKDVQQRLFRQQIAIAKR
CCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
TNMPIVIHNRDATADVLDILEEEHAEEVGGVFHSYSMSVELLPRCLDLNFYISLGGPVTF
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCEEEEEEECCEEEE
KNAKVPKAVAQEVPLDRLLVETDCPYLTPTPFRGKRNEPAYVKYVAEEIATLRDMPYDEL
CCCCCCHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHH
AAATTVNAKKLFRLP
HHHHCCCHHHHCCCC
>Mature Secondary Structure
MLIDTHTHINAEQFSEDVEETIERAREAGVSPLLVVGFDTPTIDRAIELAETHEDIYAIV
CEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCEEEEE
GWHPVDAIDCTDADLARIETLMSHPKVMALGEIGLDYHWDKSPKDVQQRLFRQQIAIAKR
CCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
TNMPIVIHNRDATADVLDILEEEHAEEVGGVFHSYSMSVELLPRCLDLNFYISLGGPVTF
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCEEEEEEECCEEEE
KNAKVPKAVAQEVPLDRLLVETDCPYLTPTPFRGKRNEPAYVKYVAEEIATLRDMPYDEL
CCCCCCHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHH
AAATTVNAKKLFRLP
HHHHCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]