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The map label for this gene is clpC [H]

Identifier: 229917386

GI number: 229917386

Start: 1603590

End: 1606025

Strand: Reverse

Name: clpC [H]

Synonym: EAT1b_1661

Alternate gene names: 229917386

Gene position: 1606025-1603590 (Counterclockwise)

Preceding gene: 229917387

Following gene: 229917385

Centisome position: 53.54

GC content: 50.12

Gene sequence:

>2436_bases
ATGATGTTTGGACGATTTACAGAACGAGCACAACGCGTATTAGCTTTAGCACAAGAGGAAGCCGTACGTCTTGGCCATCA
TAATATTGGTACAGAACATATTTTATTAGGATTGGTTCGTGAAGGAGAAGGAATCGCGGCAAAAGCGCTCTTCGCCCTCG
GATTGACCTCTGAAAAAATCCAACAAGAAGTAGAATCATTGATTGGTCGCGGTTCGGAGAACGGGTCGACGATTCATTAC
ACACCGCGTGCGAAAAAGGTCATTGAGCTCTCGATGGATGAGGCTCGGAAATTGGGACACTCTTACGTCGGAACGGAACA
CATCCTTCTAGGATTGATTCGTGAAGGAGAAGGGGTCGCGGCACGCGTCCTCAATAACCTTGGAATCAGTTTGACGAAAG
CACGCCAACAAGTGTTGCAACTTCTCGGGAACACGGAGTCATCTTCAAATGCTTCGCAACCTGGGGCGAGCGCCGCAACC
CCAACGCTTGACGGATTGGCACGCGATTTGACACAACAAGCACGCGAGTCTCGTTTGGATCCGGTCATCGGGCGTGCAGG
CGAAATTCAACGTGTCATCGAAGTATTGTCGCGTCGGACGAAGAACAACCCGGTTCTAATTGGGGAACCAGGGGTCGGGA
AAACAGCGGTCGTCGAAGGTCTCGCTCAGCAAATCATCAACAACGAGGTACCTGAAACGCTTCGCAACAAACGCGTCATG
GTACTCGACATGGGTACACTCGTCGCAGGTACAAAATATCGTGGTGAGTTCGAAGATCGCTTGAAAAAAGTAATGGACGA
AATTCGTCAAGCCGGTAACGTCATTCTCTTCATCGATGAGTTGCACACATTGATCGGTGCGGGTGGTGCAGAAGGTGCAA
TCGATGCGTCGAACATCCTCAAACCGTCATTGGCTCGCGGCGAACTTCAATGTATCGGGGCGACTACACTTGATGAATAC
CGGAAGTACATCGAAAAAGATGCAGCGCTTGAGCGCCGCTTCCAACCGATTCAAGTGAACGAACCGACAACAGAAGAAGC
TGAACAAATCTTACTCGGGTTACGCGATCGCTATGAAGCACACCACCGTGTGACGATTACAGATACGGCGATTCACGAGG
CGGTCGTCCTTTCAGACCGTTACATCTCAGATCGTTTCTTGCCGGATAAGGCGATCGACCTCGTCGACGAGGCGGCATCG
AAAGTACGACTTCGCTCATTCACGGCACCACCGAATTTGAAAGAGTTGGAATCCCGTCTCGAATCGATTCGTAAAGAGAA
AGACTCTGCCGTTCAAAGCCAAGAGTTTGAAAAAGCAGCTTCCCTTCGCGATACGGAACAAAAGTTACGCGATGAGTTAG
AAGAGTTGAAAGCAGAGTGGCAGAACAAGCAAGGGAACGAAAAACTTGAAGTGACGAAAGAAGATATCGCTCAAGTTGTT
GCGAACTGGACAGGTGTACCGGTCACGAAGATTGCCGAAGAAGAGACAGACCGTCTCCTTAAACTCGAATCGATTCTTCA
CAACCGGGTCATCGGTCAAGACGATGCGGTGAAATCCATTTCCCGCGCCATCCGTCGCGCCCGGGCCGGATTGAAAGATC
CGAAACGTCCAATCGGGTCATTCATCTTCCTCGGACCGACCGGAGTCGGGAAAACAGAGCTCGCCCGTGCAGTTGCCGAA
GCGATGTTTGGCGATGAAGATGCCATCATCCGAATCGACATGTCCGAGTACATGGAGAAACATGCGACGAGCCGTCTCGT
CGGTTCGCCTCCTGGTTATGTTGGTTACGAAGAAGGCGGTCAATTGACTGAAAAAGTGCGTCGGAAACCGTACTCGGTTA
TCCTACTCGATGAAATCGAAAAAGCGCACCCAGAAGTATTCAACATCTTGCTTCAAGTGTTAGACGACGGTCGCTTGACG
GATTCGAAAGGTCGCACCGTCGACTTCCGAAACACTGTCATCATCATGACGTCTAACGTCGGAGCCGCAGCGCTTCAACG
AAACAAATATGTAGGATTCACAGTGGAAGATGATGTGAAGCGTGAGTATACAGAAATGAAGGACAAAGTACTCGAGGAAT
TGAAGAAAGCGTTCCGACCTGAGTTCTTGAACCGGATTGATGAAATCACGGTATTCCATTCACTTCAAAAAGAGCACATT
CAAGAAATCATCAAACTTATGGCAGAGACACTCAAGAAACGTCTCGCCGAACAAGGTGTTGATTTCAGCTTGACGGATGC
GGCACTCGATAAAATTGCCGATGTCGGCTACGATCCGGAATACGGGGCTCGTCCTCTCCGTCGTGCCCTTCAACGGGAAG
TGGAGGACCGCCTCTCAGAAGCAATGCTCGGCGGCACAATCGCTAGAGGCAGTAAAGTTGCGCTCGACGTACAAGATGGA
GAGTTCGTCGTTCGTAACGAAGGTGTAGTTCAGTAA

Upstream 100 bases:

>100_bases
AACATTATCTACGCAAGAACGGGATCGAGAACGAGCGACACTTGTTCGTCGGACGTTAGATCAAGGCTTAGTTTGATCCA
ACTATAAGGAGGTTATGTCA

Downstream 100 bases:

>100_bases
AACATTCAGCTCCCTCGTCGTTTAGAGGGAGCTTTTTTTAGACAGGAAGGGAACTTATGGCCAAAATTAAAACGAAATAC
GTCTGCCAATCGTGCGGATA

Product: ATPase AAA-2 domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 811; Mature: 811

Protein sequence:

>811_residues
MMFGRFTERAQRVLALAQEEAVRLGHHNIGTEHILLGLVREGEGIAAKALFALGLTSEKIQQEVESLIGRGSENGSTIHY
TPRAKKVIELSMDEARKLGHSYVGTEHILLGLIREGEGVAARVLNNLGISLTKARQQVLQLLGNTESSSNASQPGASAAT
PTLDGLARDLTQQARESRLDPVIGRAGEIQRVIEVLSRRTKNNPVLIGEPGVGKTAVVEGLAQQIINNEVPETLRNKRVM
VLDMGTLVAGTKYRGEFEDRLKKVMDEIRQAGNVILFIDELHTLIGAGGAEGAIDASNILKPSLARGELQCIGATTLDEY
RKYIEKDAALERRFQPIQVNEPTTEEAEQILLGLRDRYEAHHRVTITDTAIHEAVVLSDRYISDRFLPDKAIDLVDEAAS
KVRLRSFTAPPNLKELESRLESIRKEKDSAVQSQEFEKAASLRDTEQKLRDELEELKAEWQNKQGNEKLEVTKEDIAQVV
ANWTGVPVTKIAEEETDRLLKLESILHNRVIGQDDAVKSISRAIRRARAGLKDPKRPIGSFIFLGPTGVGKTELARAVAE
AMFGDEDAIIRIDMSEYMEKHATSRLVGSPPGYVGYEEGGQLTEKVRRKPYSVILLDEIEKAHPEVFNILLQVLDDGRLT
DSKGRTVDFRNTVIIMTSNVGAAALQRNKYVGFTVEDDVKREYTEMKDKVLEELKKAFRPEFLNRIDEITVFHSLQKEHI
QEIIKLMAETLKKRLAEQGVDFSLTDAALDKIADVGYDPEYGARPLRRALQREVEDRLSEAMLGGTIARGSKVALDVQDG
EFVVRNEGVVQ

Sequences:

>Translated_811_residues
MMFGRFTERAQRVLALAQEEAVRLGHHNIGTEHILLGLVREGEGIAAKALFALGLTSEKIQQEVESLIGRGSENGSTIHY
TPRAKKVIELSMDEARKLGHSYVGTEHILLGLIREGEGVAARVLNNLGISLTKARQQVLQLLGNTESSSNASQPGASAAT
PTLDGLARDLTQQARESRLDPVIGRAGEIQRVIEVLSRRTKNNPVLIGEPGVGKTAVVEGLAQQIINNEVPETLRNKRVM
VLDMGTLVAGTKYRGEFEDRLKKVMDEIRQAGNVILFIDELHTLIGAGGAEGAIDASNILKPSLARGELQCIGATTLDEY
RKYIEKDAALERRFQPIQVNEPTTEEAEQILLGLRDRYEAHHRVTITDTAIHEAVVLSDRYISDRFLPDKAIDLVDEAAS
KVRLRSFTAPPNLKELESRLESIRKEKDSAVQSQEFEKAASLRDTEQKLRDELEELKAEWQNKQGNEKLEVTKEDIAQVV
ANWTGVPVTKIAEEETDRLLKLESILHNRVIGQDDAVKSISRAIRRARAGLKDPKRPIGSFIFLGPTGVGKTELARAVAE
AMFGDEDAIIRIDMSEYMEKHATSRLVGSPPGYVGYEEGGQLTEKVRRKPYSVILLDEIEKAHPEVFNILLQVLDDGRLT
DSKGRTVDFRNTVIIMTSNVGAAALQRNKYVGFTVEDDVKREYTEMKDKVLEELKKAFRPEFLNRIDEITVFHSLQKEHI
QEIIKLMAETLKKRLAEQGVDFSLTDAALDKIADVGYDPEYGARPLRRALQREVEDRLSEAMLGGTIARGSKVALDVQDG
EFVVRNEGVVQ
>Mature_811_residues
MMFGRFTERAQRVLALAQEEAVRLGHHNIGTEHILLGLVREGEGIAAKALFALGLTSEKIQQEVESLIGRGSENGSTIHY
TPRAKKVIELSMDEARKLGHSYVGTEHILLGLIREGEGVAARVLNNLGISLTKARQQVLQLLGNTESSSNASQPGASAAT
PTLDGLARDLTQQARESRLDPVIGRAGEIQRVIEVLSRRTKNNPVLIGEPGVGKTAVVEGLAQQIINNEVPETLRNKRVM
VLDMGTLVAGTKYRGEFEDRLKKVMDEIRQAGNVILFIDELHTLIGAGGAEGAIDASNILKPSLARGELQCIGATTLDEY
RKYIEKDAALERRFQPIQVNEPTTEEAEQILLGLRDRYEAHHRVTITDTAIHEAVVLSDRYISDRFLPDKAIDLVDEAAS
KVRLRSFTAPPNLKELESRLESIRKEKDSAVQSQEFEKAASLRDTEQKLRDELEELKAEWQNKQGNEKLEVTKEDIAQVV
ANWTGVPVTKIAEEETDRLLKLESILHNRVIGQDDAVKSISRAIRRARAGLKDPKRPIGSFIFLGPTGVGKTELARAVAE
AMFGDEDAIIRIDMSEYMEKHATSRLVGSPPGYVGYEEGGQLTEKVRRKPYSVILLDEIEKAHPEVFNILLQVLDDGRLT
DSKGRTVDFRNTVIIMTSNVGAAALQRNKYVGFTVEDDVKREYTEMKDKVLEELKKAFRPEFLNRIDEITVFHSLQKEHI
QEIIKLMAETLKKRLAEQGVDFSLTDAALDKIADVGYDPEYGARPLRRALQREVEDRLSEAMLGGTIARGSKVALDVQDG
EFVVRNEGVVQ

Specific function: Competence gene repressor; required for cell growth at high temperature. Negative regulator of comK expression. May interact with MecA to negatively regulate comK [H]

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=322, Percent_Identity=35.7142857142857, Blast_Score=205, Evalue=2e-52,
Organism=Escherichia coli, GI1788943, Length=871, Percent_Identity=48.105625717566, Blast_Score=760, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=799, Percent_Identity=38.0475594493116, Blast_Score=517, Evalue=1e-147,
Organism=Saccharomyces cerevisiae, GI6320464, Length=714, Percent_Identity=48.5994397759104, Blast_Score=645, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=886, Percent_Identity=36.4559819413093, Blast_Score=521, Evalue=1e-148,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 90166; Mature: 90166

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS50151 UVR ; PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMFGRFTERAQRVLALAQEEAVRLGHHNIGTEHILLGLVREGEGIAAKALFALGLTSEKI
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCHHHH
QQEVESLIGRGSENGSTIHYTPRAKKVIELSMDEARKLGHSYVGTEHILLGLIREGEGVA
HHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHH
ARVLNNLGISLTKARQQVLQLLGNTESSSNASQPGASAATPTLDGLARDLTQQARESRLD
HHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
PVIGRAGEIQRVIEVLSRRTKNNPVLIGEPGVGKTAVVEGLAQQIINNEVPETLRNKRVM
HHHCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHCCEEE
VLDMGTLVAGTKYRGEFEDRLKKVMDEIRQAGNVILFIDELHTLIGAGGAEGAIDASNIL
EEECCHHHCCCCCCCCHHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCCCCCHHHHC
KPSLARGELQCIGATTLDEYRKYIEKDAALERRFQPIQVNEPTTEEAEQILLGLRDRYEA
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCC
HHRVTITDTAIHEAVVLSDRYISDRFLPDKAIDLVDEAASKVRLRSFTAPPNLKELESRL
CCEEEEEHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ESIRKEKDSAVQSQEFEKAASLRDTEQKLRDELEELKAEWQNKQGNEKLEVTKEDIAQVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHH
ANWTGVPVTKIAEEETDRLLKLESILHNRVIGQDDAVKSISRAIRRARAGLKDPKRPIGS
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
FIFLGPTGVGKTELARAVAEAMFGDEDAIIRIDMSEYMEKHATSRLVGSPPGYVGYEEGG
EEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCC
QLTEKVRRKPYSVILLDEIEKAHPEVFNILLQVLDDGRLTDSKGRTVDFRNTVIIMTSNV
HHHHHHHHCCCEEEEEHHHHHHCHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECCC
GAAALQRNKYVGFTVEDDVKREYTEMKDKVLEELKKAFRPEFLNRIDEITVFHSLQKEHI
CHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
QEIIKLMAETLKKRLAEQGVDFSLTDAALDKIADVGYDPEYGARPLRRALQREVEDRLSE
HHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
AMLGGTIARGSKVALDVQDGEFVVRNEGVVQ
HHHCCHHCCCCEEEEEECCCCEEEECCCCCC
>Mature Secondary Structure
MMFGRFTERAQRVLALAQEEAVRLGHHNIGTEHILLGLVREGEGIAAKALFALGLTSEKI
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCHHHH
QQEVESLIGRGSENGSTIHYTPRAKKVIELSMDEARKLGHSYVGTEHILLGLIREGEGVA
HHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHH
ARVLNNLGISLTKARQQVLQLLGNTESSSNASQPGASAATPTLDGLARDLTQQARESRLD
HHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
PVIGRAGEIQRVIEVLSRRTKNNPVLIGEPGVGKTAVVEGLAQQIINNEVPETLRNKRVM
HHHCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHCCEEE
VLDMGTLVAGTKYRGEFEDRLKKVMDEIRQAGNVILFIDELHTLIGAGGAEGAIDASNIL
EEECCHHHCCCCCCCCHHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCCCCCHHHHC
KPSLARGELQCIGATTLDEYRKYIEKDAALERRFQPIQVNEPTTEEAEQILLGLRDRYEA
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCC
HHRVTITDTAIHEAVVLSDRYISDRFLPDKAIDLVDEAASKVRLRSFTAPPNLKELESRL
CCEEEEEHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ESIRKEKDSAVQSQEFEKAASLRDTEQKLRDELEELKAEWQNKQGNEKLEVTKEDIAQVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHH
ANWTGVPVTKIAEEETDRLLKLESILHNRVIGQDDAVKSISRAIRRARAGLKDPKRPIGS
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
FIFLGPTGVGKTELARAVAEAMFGDEDAIIRIDMSEYMEKHATSRLVGSPPGYVGYEEGG
EEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCC
QLTEKVRRKPYSVILLDEIEKAHPEVFNILLQVLDDGRLTDSKGRTVDFRNTVIIMTSNV
HHHHHHHHCCCEEEEEHHHHHHCHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECCC
GAAALQRNKYVGFTVEDDVKREYTEMKDKVLEELKKAFRPEFLNRIDEITVFHSLQKEHI
CHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
QEIIKLMAETLKKRLAEQGVDFSLTDAALDKIADVGYDPEYGARPLRRALQREVEDRLSE
HHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
AMLGGTIARGSKVALDVQDGEFVVRNEGVVQ
HHHCCHHCCCCEEEEEECCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8016066; 7584024; 9384377; 8195092 [H]