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The map label for this gene is 229917387

Identifier: 229917387

GI number: 229917387

Start: 1606050

End: 1607093

Strand: Reverse

Name: 229917387

Synonym: EAT1b_1662

Alternate gene names: NA

Gene position: 1607093-1606050 (Counterclockwise)

Preceding gene: 229917388

Following gene: 229917386

Centisome position: 53.57

GC content: 45.98

Gene sequence:

>1044_bases
ATGGAAACGTTCCTAACACATCCACTTGGTCCAAAAATGAAAGAGCGTGCCAAATTGGATGACCTGGTCGTCTCTACAAG
AATCCGACTGGCACGTAACGTCAAAGACACTGTGTTTTCGCCGGTCCTCTCTAAAGAAGGAGAACGTCAACTTTGTGATC
GTCTCGAAGGGCGGTTACGTGGGTTAAAAGGATTTGAATATCTTCATATGCGTGACTATGATGAGGTCACCCGGCAGGCG
TTGATGGAAAAACACTTAATTAGTCCGGCCGTTGCGGCAAACGAAGAAAGTGCAGTCTTTTTAAGTGAAGATGAAACCAT
CAGTGTGTTGATTAACGAAGAAGATCATTTACGAATTCAGACCTTACTCCCAGGTTATCAAGTGAAAGAGGCGTTTGAAT
TAGCGAATCAAGTAGACGCATTGTGCGCAGAATCACTCTCCTACGCCTTTGACGAACAGTTAGGCTACTTGACGACATGC
CCAAGCAATATCGGAACCGGACTCCGGGCCTCGGTCATGTTACACTTACCGGGACTCACGTTAACGGGTCGAATCAGCCC
CATTTTGCGAGAACTTCGAAAACTCGGCTATACGATTCGAGGTCGTTATGGAGAAGGCAGCGATGCGGCAGGACGGTTGT
TCCAGCTGTCAAATCAGCGGACATTGGGCAGTCATGAATCACAGCTGTTAGCTGACTTTATGGAAGTGACAGAACAAGTG
ATTCAAGCAGAACGTCATGCGCGTGAAGAGCTCATCGCACATCGACAAGAAGAGTTAGAGGATCGGTTTTATCGGTCATA
TGGTATTTTACGATATGCCAAACTTCTTTCTTCTACGGAAGCCATTGAGCGACTATCTGATTTACATTTAGCGAGTGACT
TAGGGATTTTGTCTGATTGGAGTCCGCCGAAGTTCCATGAACTCATCGTTCGGTTACAATCAGGTTTTCTACAAAAACAT
TTCGGGAAAACATTATCTACGCAAGAACGGGATCGAGAACGAGCGACACTTGTTCGTCGGACGTTAGATCAAGGCTTAGT
TTGA

Upstream 100 bases:

>100_bases
TGGCAGGGGAGTTGACCCGCGCTGTCGAACAAGAAGATTATGAACGAGCAGCACGTATTCAAAAAGAAATGAAGCAATTA
GAAGGGCAAGGTGATGTCTA

Downstream 100 bases:

>100_bases
TCCAACTATAAGGAGGTTATGTCAATGATGTTTGGACGATTTACAGAACGAGCACAACGCGTATTAGCTTTAGCACAAGA
GGAAGCCGTACGTCTTGGCC

Product: ATP:guanido phosphotransferase

Products: ADP; N-phospho-L-arginine

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
METFLTHPLGPKMKERAKLDDLVVSTRIRLARNVKDTVFSPVLSKEGERQLCDRLEGRLRGLKGFEYLHMRDYDEVTRQA
LMEKHLISPAVAANEESAVFLSEDETISVLINEEDHLRIQTLLPGYQVKEAFELANQVDALCAESLSYAFDEQLGYLTTC
PSNIGTGLRASVMLHLPGLTLTGRISPILRELRKLGYTIRGRYGEGSDAAGRLFQLSNQRTLGSHESQLLADFMEVTEQV
IQAERHAREELIAHRQEELEDRFYRSYGILRYAKLLSSTEAIERLSDLHLASDLGILSDWSPPKFHELIVRLQSGFLQKH
FGKTLSTQERDRERATLVRRTLDQGLV

Sequences:

>Translated_347_residues
METFLTHPLGPKMKERAKLDDLVVSTRIRLARNVKDTVFSPVLSKEGERQLCDRLEGRLRGLKGFEYLHMRDYDEVTRQA
LMEKHLISPAVAANEESAVFLSEDETISVLINEEDHLRIQTLLPGYQVKEAFELANQVDALCAESLSYAFDEQLGYLTTC
PSNIGTGLRASVMLHLPGLTLTGRISPILRELRKLGYTIRGRYGEGSDAAGRLFQLSNQRTLGSHESQLLADFMEVTEQV
IQAERHAREELIAHRQEELEDRFYRSYGILRYAKLLSSTEAIERLSDLHLASDLGILSDWSPPKFHELIVRLQSGFLQKH
FGKTLSTQERDRERATLVRRTLDQGLV
>Mature_347_residues
METFLTHPLGPKMKERAKLDDLVVSTRIRLARNVKDTVFSPVLSKEGERQLCDRLEGRLRGLKGFEYLHMRDYDEVTRQA
LMEKHLISPAVAANEESAVFLSEDETISVLINEEDHLRIQTLLPGYQVKEAFELANQVDALCAESLSYAFDEQLGYLTTC
PSNIGTGLRASVMLHLPGLTLTGRISPILRELRKLGYTIRGRYGEGSDAAGRLFQLSNQRTLGSHESQLLADFMEVTEQV
IQAERHAREELIAHRQEELEDRFYRSYGILRYAKLLSSTEAIERLSDLHLASDLGILSDWSPPKFHELIVRLQSGFLQKH
FGKTLSTQERDRERATLVRRTLDQGLV

Specific function: Unknown

COG id: COG3869

COG function: function code E; Arginine kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 phosphagen kinase C-terminal domain

Homologues:

Organism=Homo sapiens, GI21536286, Length=251, Percent_Identity=29.8804780876494, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI66346730, Length=243, Percent_Identity=29.6296296296296, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI10334859, Length=243, Percent_Identity=29.6296296296296, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI310110654, Length=263, Percent_Identity=28.5171102661597, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI153252003, Length=243, Percent_Identity=28.3950617283951, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI153251984, Length=243, Percent_Identity=28.3950617283951, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI153251982, Length=243, Percent_Identity=28.3950617283951, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI21536288, Length=251, Percent_Identity=28.2868525896414, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI310110652, Length=153, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI310110650, Length=183, Percent_Identity=31.1475409836066, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI310110648, Length=136, Percent_Identity=32.3529411764706, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17511011, Length=251, Percent_Identity=29.8804780876494, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17507069, Length=258, Percent_Identity=29.0697674418605, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17509681, Length=258, Percent_Identity=28.6821705426357, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17560974, Length=254, Percent_Identity=27.9527559055118, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI32566409, Length=241, Percent_Identity=26.5560165975104, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71990551, Length=241, Percent_Identity=26.5560165975104, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24661332, Length=246, Percent_Identity=31.3008130081301, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI161082598, Length=241, Percent_Identity=25.7261410788382, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI221331031, Length=241, Percent_Identity=25.7261410788382, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24661348, Length=241, Percent_Identity=25.7261410788382, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24661344, Length=241, Percent_Identity=25.7261410788382, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24661336, Length=241, Percent_Identity=25.7261410788382, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24661340, Length=241, Percent_Identity=25.7261410788382, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24647265, Length=242, Percent_Identity=28.9256198347107, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1662_EXISA (C4KZS5)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002886033.1
- GeneID:   7869723
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_1662
- OMA:   DRVFRSY
- ProtClustDB:   CLSK2488853
- HAMAP:   MF_00602
- InterPro:   IPR000749
- InterPro:   IPR022414
- InterPro:   IPR022415
- InterPro:   IPR014746
- Gene3D:   G3DSA:3.30.590.10
- PANTHER:   PTHR11547

Pfam domain/function: PF00217 ATP-gua_Ptrans

EC number: 2.7.3.3

Molecular weight: Translated: 39509; Mature: 39509

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00112 PHOSPHAGEN_KINASE; PS51510 PHOSPHAGEN_KINASE_C

Important sites: BINDING 85-85 BINDING 118-118

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METFLTHPLGPKMKERAKLDDLVVSTRIRLARNVKDTVFSPVLSKEGERQLCDRLEGRLR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
GLKGFEYLHMRDYDEVTRQALMEKHLISPAVAANEESAVFLSEDETISVLINEEDHLRIQ
CCCCCHHHHHCCHHHHHHHHHHHHHHCCCHHHCCCCCEEEEECCCEEEEEECCCCCEEEE
TLLPGYQVKEAFELANQVDALCAESLSYAFDEQLGYLTTCPSNIGTGLRASVMLHLPGLT
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHCCCHHHHHEEEECCCC
LTGRISPILRELRKLGYTIRGRYGEGSDAAGRLFQLSNQRTLGSHESQLLADFMEVTEQV
CCCCHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
IQAERHAREELIAHRQEELEDRFYRSYGILRYAKLLSSTEAIERLSDLHLASDLGILSDW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SPPKFHELIVRLQSGFLQKHFGKTLSTQERDRERATLVRRTLDQGLV
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
METFLTHPLGPKMKERAKLDDLVVSTRIRLARNVKDTVFSPVLSKEGERQLCDRLEGRLR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
GLKGFEYLHMRDYDEVTRQALMEKHLISPAVAANEESAVFLSEDETISVLINEEDHLRIQ
CCCCCHHHHHCCHHHHHHHHHHHHHHCCCHHHCCCCCEEEEECCCEEEEEECCCCCEEEE
TLLPGYQVKEAFELANQVDALCAESLSYAFDEQLGYLTTCPSNIGTGLRASVMLHLPGLT
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHCCCHHHHHEEEECCCC
LTGRISPILRELRKLGYTIRGRYGEGSDAAGRLFQLSNQRTLGSHESQLLADFMEVTEQV
CCCCHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
IQAERHAREELIAHRQEELEDRFYRSYGILRYAKLLSSTEAIERLSDLHLASDLGILSDW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SPPKFHELIVRLQSGFLQKHFGKTLSTQERDRERATLVRRTLDQGLV
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-arginine

Specific reaction: ATP + L-arginine = ADP + N-phospho-L-arginine

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA