Click here to switch to the map view.

The map label for this gene is arcR [H]

Identifier: 229917197

GI number: 229917197

Start: 1439667

End: 1440356

Strand: Reverse

Name: arcR [H]

Synonym: EAT1b_1472

Alternate gene names: 229917197

Gene position: 1440356-1439667 (Counterclockwise)

Preceding gene: 229917198

Following gene: 229917196

Centisome position: 48.01

GC content: 48.12

Gene sequence:

>690_bases
ATGCGACATAAGTGGACGATTGATGATTTACGCCAGTTGACACTGTTTGCGAACTGTTCGAGTCGAGCGCTTGAACAGCT
CGTCCCGCACGTCTATTGCCGAACATATCGAAAAGGACAGCTCCTGTTCATGGAAGGAGACCCGCGAGAGCGCGTGTATT
TCTTAATGAGTGGATACATCAGACTCGAACGGATGAACGAGCATGCGACGCATCAATATGCGGACTACGTGAAGCCCAAA
CAGTTCTTTCCGTACAATGGTTTGTTCACGGAGGAAGACTACCGTCATACGGCCGAAGCGGTGACGGATATTGACGTCAT
CTACATCCCGACCGAACGGTTCGAGCGGTTTGTATCTACACAGTCGAATATGCTGCTCTATATCATCGGACAGATGAATC
GTATTTTAGATTTACATGAACGACGTGTCCAAGAGATCATTACCCCGAGCGCGAAAGAACGTGTACTCAATACCATCCAT
TTTTTGATTGAAGATTTAGGTGAACCGGATGAGCAAGGGGTACGTGTCCGCTGTCCGTTCACGGCGATGGAACTATCTCG
TCTATCTGGAACGTCCCGAGAGACGGTTTCTACGATTTTAGCGAAGCTTCGTAAAGAAGAGGTGCTTCGAATGGATGACC
ACCAACTTGTCATCGGGCATCCTGAATACTTTGAGCAAGACTTCGATTGA

Upstream 100 bases:

>100_bases
CTTTTGTCATGTCAGAAAACTGTCGGATTTTGAAAGCGGTATCATTCTGAATCGTTTTATACTTAAGGTAGGGGATTTAA
CTAGAAATGAGGGGATACAG

Downstream 100 bases:

>100_bases
CGCCACTCAGGAGAGGGCGTCTTTTGCATGTCGGAACGAGCGGAGCGTTCGCTTCAAGACGTGTCATATTGTATAATTAG
TGATGAATCTCACAAAGCAA

Product: Crp/Fnr family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MRHKWTIDDLRQLTLFANCSSRALEQLVPHVYCRTYRKGQLLFMEGDPRERVYFLMSGYIRLERMNEHATHQYADYVKPK
QFFPYNGLFTEEDYRHTAEAVTDIDVIYIPTERFERFVSTQSNMLLYIIGQMNRILDLHERRVQEIITPSAKERVLNTIH
FLIEDLGEPDEQGVRVRCPFTAMELSRLSGTSRETVSTILAKLRKEEVLRMDDHQLVIGHPEYFEQDFD

Sequences:

>Translated_229_residues
MRHKWTIDDLRQLTLFANCSSRALEQLVPHVYCRTYRKGQLLFMEGDPRERVYFLMSGYIRLERMNEHATHQYADYVKPK
QFFPYNGLFTEEDYRHTAEAVTDIDVIYIPTERFERFVSTQSNMLLYIIGQMNRILDLHERRVQEIITPSAKERVLNTIH
FLIEDLGEPDEQGVRVRCPFTAMELSRLSGTSRETVSTILAKLRKEEVLRMDDHQLVIGHPEYFEQDFD
>Mature_229_residues
MRHKWTIDDLRQLTLFANCSSRALEQLVPHVYCRTYRKGQLLFMEGDPRERVYFLMSGYIRLERMNEHATHQYADYVKPK
QFFPYNGLFTEEDYRHTAEAVTDIDVIYIPTERFERFVSTQSNMLLYIIGQMNRILDLHERRVQEIITPSAKERVLNTIH
FLIEDLGEPDEQGVRVRCPFTAMELSRLSGTSRETVSTILAKLRKEEVLRMDDHQLVIGHPEYFEQDFD

Specific function: Positively regulates the expression of the arcABDCR operon under anaerobic conditions, thus playing an essential role in arginine catabolism. May also control the expression of genes encoding proteins which are involved in anaerobic metabolism. Can bind c

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR014710
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding [H]

EC number: NA

Molecular weight: Translated: 27227; Mature: 27227

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHKWTIDDLRQLTLFANCSSRALEQLVPHVYCRTYRKGQLLFMEGDPRERVYFLMSGYI
CCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHH
RLERMNEHATHQYADYVKPKQFFPYNGLFTEEDYRHTAEAVTDIDVIYIPTERFERFVST
HEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEECHHHHHHHHCC
QSNMLLYIIGQMNRILDLHERRVQEIITPSAKERVLNTIHFLIEDLGEPDEQGVRVRCPF
CCCEEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCH
TAMELSRLSGTSRETVSTILAKLRKEEVLRMDDHQLVIGHPEYFEQDFD
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHCCCCC
>Mature Secondary Structure
MRHKWTIDDLRQLTLFANCSSRALEQLVPHVYCRTYRKGQLLFMEGDPRERVYFLMSGYI
CCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHH
RLERMNEHATHQYADYVKPKQFFPYNGLFTEEDYRHTAEAVTDIDVIYIPTERFERFVST
HEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEECHHHHHHHHCC
QSNMLLYIIGQMNRILDLHERRVQEIITPSAKERVLNTIHFLIEDLGEPDEQGVRVRCPF
CCCEEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCH
TAMELSRLSGTSRETVSTILAKLRKEEVLRMDDHQLVIGHPEYFEQDFD
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA