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The map label for this gene is mtnA [H]

Identifier: 229917160

GI number: 229917160

Start: 1401879

End: 1402913

Strand: Reverse

Name: mtnA [H]

Synonym: EAT1b_1434

Alternate gene names: 229917160

Gene position: 1402913-1401879 (Counterclockwise)

Preceding gene: 229917161

Following gene: 229917159

Centisome position: 46.77

GC content: 53.43

Gene sequence:

>1035_bases
ATGAGTGTGCAAAGTATTCATTTCGATGCCGACACGGAAGTGTTGACGATTTTAGATCAGACGCTGTTGCCGCAAGAAGA
GCGCTATGTCGAAGTGTTGACGCTCGAACAGGCCGAGCAGGCAATCAAGTCGCTTCAAGTTCGCGGTGCACCGGCCATCG
CTTATTTCGGAGCGTTTGTCCTTGCGAAAGAAGCGTCACGTCTGCAAGACAATCCATATTTTCATCTCCAATTGAATCAA
GTCGGTCAACGGTTGATTGCGACAAGACCGACCGCGGTCAACTTACAGCATGTCATCGAATCACTCCTTCGATTGAATGT
GGGGGAGGACTTTGAACAGATTGCAAAAGCAATCAAGCAGCGTGCGATTGAAATCTTTGAACAAGACGTGGCTACGTATC
GCACGATTGGGGAACATGCGCTCACCGTGTTACCCGCTGGTGGCAACGTATTGACGATTTGTAACGCCGGTGCCATCGCG
ACGTCACGATACGGTACCGCGCTCGCGCCGTTCTATGTCGGGAAAGAGCGTGGCATCCCGTTTCGGGTGTTCGCGTCCGA
AACGCGACCGCTGCTTCAAGGGGCACGGTTGACGGTATGGGAGCTCGACCGGGCGGACATCGACGTCACATTGATCACGG
ATAATATGGCGGCGTGGACGATCCAGACGAAACAAATCGATGCCATCATCGTCGGGGCGGACCGCATCACCCGTACCGGT
CATACGGCCAACAAGATTGGAACACTCCAGCTTGCGATTTTGGCGAAGCATTACGGCATCCCATTCTATGTGGCAGCCCC
GCATTCGACGTTCGATTTAGAGGCGGACGACACGATTCAAATCGAGGAACGGGACGCCCATGAAGTGACCCATATCGGAG
GACATCCAACGGCACTCGTCGGCATCACCGTCTTCAATCCGGCGTTTGATGTGACCCCACCCGAACTGATCACCGGTCTG
ATCACAGAGACTGGTGTGCTCGAACCGACTGAGTCGGTCATTGTAGAACATGTAGGAGGAAACACATATGTCTAA

Upstream 100 bases:

>100_bases
GGAAACGCCACGCCTTAGAGCTCGGTACGCGTCTCATCAAACAGCGCCATCAAATTCAATCCATCGATCAATTGATTCCA
GTCTTGTCGGAGGTGCGCGT

Downstream 100 bases:

>100_bases
AAAAATCATCTTCTTCCTGTTGACCGTCATCTTAGCACTTGCCGGATGCACGAACGAACAGGCGCAACCGAAAACGACTA
CGACAACAAGTAAAACGGAA

Product: translation initiation factor, aIF-2BI family

Products: NA

Alternate protein names: M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MSVQSIHFDADTEVLTILDQTLLPQEERYVEVLTLEQAEQAIKSLQVRGAPAIAYFGAFVLAKEASRLQDNPYFHLQLNQ
VGQRLIATRPTAVNLQHVIESLLRLNVGEDFEQIAKAIKQRAIEIFEQDVATYRTIGEHALTVLPAGGNVLTICNAGAIA
TSRYGTALAPFYVGKERGIPFRVFASETRPLLQGARLTVWELDRADIDVTLITDNMAAWTIQTKQIDAIIVGADRITRTG
HTANKIGTLQLAILAKHYGIPFYVAAPHSTFDLEADDTIQIEERDAHEVTHIGGHPTALVGITVFNPAFDVTPPELITGL
ITETGVLEPTESVIVEHVGGNTYV

Sequences:

>Translated_344_residues
MSVQSIHFDADTEVLTILDQTLLPQEERYVEVLTLEQAEQAIKSLQVRGAPAIAYFGAFVLAKEASRLQDNPYFHLQLNQ
VGQRLIATRPTAVNLQHVIESLLRLNVGEDFEQIAKAIKQRAIEIFEQDVATYRTIGEHALTVLPAGGNVLTICNAGAIA
TSRYGTALAPFYVGKERGIPFRVFASETRPLLQGARLTVWELDRADIDVTLITDNMAAWTIQTKQIDAIIVGADRITRTG
HTANKIGTLQLAILAKHYGIPFYVAAPHSTFDLEADDTIQIEERDAHEVTHIGGHPTALVGITVFNPAFDVTPPELITGL
ITETGVLEPTESVIVEHVGGNTYV
>Mature_343_residues
SVQSIHFDADTEVLTILDQTLLPQEERYVEVLTLEQAEQAIKSLQVRGAPAIAYFGAFVLAKEASRLQDNPYFHLQLNQV
GQRLIATRPTAVNLQHVIESLLRLNVGEDFEQIAKAIKQRAIEIFEQDVATYRTIGEHALTVLPAGGNVLTICNAGAIAT
SRYGTALAPFYVGKERGIPFRVFASETRPLLQGARLTVWELDRADIDVTLITDNMAAWTIQTKQIDAIIVGADRITRTGH
TANKIGTLQLAILAKHYGIPFYVAAPHSTFDLEADDTIQIEERDAHEVTHIGGHPTALVGITVFNPAFDVTPPELITGLI
TETGVLEPTESVIVEHVGGNTYV

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) [H]

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily [H]

Homologues:

Organism=Homo sapiens, GI72534748, Length=350, Percent_Identity=44.2857142857143, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI23943880, Length=341, Percent_Identity=39.8826979472141, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17557462, Length=340, Percent_Identity=36.7647058823529, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17557123, Length=275, Percent_Identity=25.4545454545455, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6325375, Length=402, Percent_Identity=37.3134328358209, Blast_Score=206, Evalue=3e-54,
Organism=Saccharomyces cerevisiae, GI6322878, Length=162, Percent_Identity=31.4814814814815, Blast_Score=63, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21357667, Length=355, Percent_Identity=41.1267605633803, Blast_Score=240, Evalue=9e-64,
Organism=Drosophila melanogaster, GI24651647, Length=355, Percent_Identity=41.1267605633803, Blast_Score=240, Evalue=9e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559 [H]

Pfam domain/function: PF01008 IF-2B [H]

EC number: =5.3.1.23 [H]

Molecular weight: Translated: 37695; Mature: 37564

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVQSIHFDADTEVLTILDQTLLPQEERYVEVLTLEQAEQAIKSLQVRGAPAIAYFGAFV
CCCCEEEECCCCHHHHHHHHHHCCCHHHEEEEEEHHHHHHHHHHHHCCCCCHHHHHHHHH
LAKEASRLQDNPYFHLQLNQVGQRLIATRPTAVNLQHVIESLLRLNVGEDFEQIAKAIKQ
HHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCEECHHHHHHHHHHCCCCCCHHHHHHHHHH
RAIEIFEQDVATYRTIGEHALTVLPAGGNVLTICNAGAIATSRYGTALAPFYVGKERGIP
HHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCEEECCCCCEECCEEECCCCCCE
FRVFASETRPLLQGARLTVWELDRADIDVTLITDNMAAWTIQTKQIDAIIVGADRITRTG
EEEEECCCCHHHCCCEEEEEEECCCCEEEEEEECCCEEEEEEECEEEEEEEECCHHCCCC
HTANKIGTLQLAILAKHYGIPFYVAAPHSTFDLEADDTIQIEERDAHEVTHIGGHPTALV
CCCCCCHHEEEEEEHHHCCCEEEEECCCCEEECCCCCEEEEECCCCCCEEECCCCCEEEE
GITVFNPAFDVTPPELITGLITETGVLEPTESVIVEHVGGNTYV
EEEEECCCCCCCCHHHHHHHHHCCCCCCCCHHHHHEECCCCCCC
>Mature Secondary Structure 
SVQSIHFDADTEVLTILDQTLLPQEERYVEVLTLEQAEQAIKSLQVRGAPAIAYFGAFV
CCCEEEECCCCHHHHHHHHHHCCCHHHEEEEEEHHHHHHHHHHHHCCCCCHHHHHHHHH
LAKEASRLQDNPYFHLQLNQVGQRLIATRPTAVNLQHVIESLLRLNVGEDFEQIAKAIKQ
HHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCEECHHHHHHHHHHCCCCCCHHHHHHHHHH
RAIEIFEQDVATYRTIGEHALTVLPAGGNVLTICNAGAIATSRYGTALAPFYVGKERGIP
HHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCEEECCCCCEECCEEECCCCCCE
FRVFASETRPLLQGARLTVWELDRADIDVTLITDNMAAWTIQTKQIDAIIVGADRITRTG
EEEEECCCCHHHCCCEEEEEEECCCCEEEEEEECCCEEEEEEECEEEEEEEECCHHCCCC
HTANKIGTLQLAILAKHYGIPFYVAAPHSTFDLEADDTIQIEERDAHEVTHIGGHPTALV
CCCCCCHHEEEEEEHHHCCCEEEEECCCCEEECCCCCEEEEECCCCCCEEECCCCCEEEE
GITVFNPAFDVTPPELITGLITETGVLEPTESVIVEHVGGNTYV
EEEEECCCCCCCCHHHHHHHHHCCCCCCCCHHHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA