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The map label for this gene is norM [H]

Identifier: 229917147

GI number: 229917147

Start: 1389897

End: 1391225

Strand: Direct

Name: norM [H]

Synonym: EAT1b_1421

Alternate gene names: 229917147

Gene position: 1389897-1391225 (Clockwise)

Preceding gene: 229917146

Following gene: 229917148

Centisome position: 46.33

GC content: 47.4

Gene sequence:

>1329_bases
GTGAAAACCGTTGATTTGACGATTGGAAACGTGCAACGCGTCATTCTGGCTCTTGCCCTTCCGCTCGTCGGTAGCTCGTT
ATTACAATTTACGTATAGTCTCGTCGACATGTTTTGGGTCGGTGCGCTCGGGAGCGATGCTGTGGCAAGTATCGGTGCAG
CTAGTTTTTATATCATGCTCGGACAGGCGATTCAATCGTTGATTGTCGTTGGCGCCGGCATCAAAGTATCACAAGCTGTT
GGGAGACGTGACCTCAATTCGGTTCAGCGTCATGTCCGGGCCAGCAGGCGTCTGAATCTAACACTTGGTCTTTCGTACGC
CTCACTACTAATTATGTTCGGTCATACATTCATCGGCTTTTTGAATATGGGTGCCCTCGCTGTGGAGCAGCTTGCGTATG
AATATTTGTTCGTCAGCGCCCCGATGCTCATCTTTTCTTTCTTTAATTTGCTGTTTGCTCGTCTATTCAGTGCATATGGC
AATACGACAACAGCGATGCGAATCAATGCGACAGGTGTCATCCTCAATATGATTCTCTCCCCGATTTTCATTTATCCATT
CCAACTCGGTGTGATCGGGGCTGCTCTTGCAACACTTGTCGCCAACGTCATGATGTTCGGATTGTTTTGGCACCGCGCTC
GTACATTATTCAATTGGGATGAAGTCGTTCAGCCGACTCGAACTGACTATAAAGAAATCATCCGTCTTGGTTTTCCGATG
GCAACCCAACGGATTTTGTTCACGGTAATCAGTATTTTTCTTGCCCGCATGATTGGCTCATACGGGACGGAAGCGATTGC
GGCACAACGCATCGGACTTCAAATCGAATCGATTGCCTACATGATGATTGGTGGCTTGAACGGAGCAATGGCTAGCTATA
CCGGTCAAAACCTCGGGGCACGAAAAGTAGATCGTGTTTATGAAGGTTACCGGGTAACGACCCGACTCGGGATGGTTTAC
ACAGGATTCATTATGTTGTTCTTTTTATTCGTCCCAGATTTACTCATTGGTCTATTCGTCGATGACGTTCGAACCATCGA
AATTGGGGCGAGCTACTTGCGAATTATCGGCATTTCGCTCGTCTTCTCATCGATTGAAATGATCGGAAACGGATACTTCT
CAGGACTCGGATTACCGAAAATCCCCGCGACCATCTCGATTATTTTCACAGTGGCCCGTATCCCGCTCGCATTTTTTCTT
GAGCCTTATCTCGGAATCGATGCTATCTGGTGGAGTATCGCCATCTCAAGTATCACAAAAGGGCTTGTCTCTGCCCTCTT
TGTCCGACTAACGAAAAAGGAAGTGATTTCCCTTGCAGAAGCAGTTTAA

Upstream 100 bases:

>100_bases
TCCATTTTTCATCGATTCGGCTATCATGATTGCCAATTCTATTACACCGTGCTTATATATAACTAAATGGTTATATAAAG
AATGTAAGGAGTCTTGCTTT

Downstream 100 bases:

>100_bases
TCAACTACCCCACCATCTCATCACAAGTGGAAAATTTGCCATCGAGCGAGAAATGTTACGAGTCACGTCAGAAGGCACAC
TAGCTGTTACGAAGCATCCA

Product: MATE efflux family protein

Products: NA

Alternate protein names: Multidrug-efflux transporter [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MKTVDLTIGNVQRVILALALPLVGSSLLQFTYSLVDMFWVGALGSDAVASIGAASFYIMLGQAIQSLIVVGAGIKVSQAV
GRRDLNSVQRHVRASRRLNLTLGLSYASLLIMFGHTFIGFLNMGALAVEQLAYEYLFVSAPMLIFSFFNLLFARLFSAYG
NTTTAMRINATGVILNMILSPIFIYPFQLGVIGAALATLVANVMMFGLFWHRARTLFNWDEVVQPTRTDYKEIIRLGFPM
ATQRILFTVISIFLARMIGSYGTEAIAAQRIGLQIESIAYMMIGGLNGAMASYTGQNLGARKVDRVYEGYRVTTRLGMVY
TGFIMLFFLFVPDLLIGLFVDDVRTIEIGASYLRIIGISLVFSSIEMIGNGYFSGLGLPKIPATISIIFTVARIPLAFFL
EPYLGIDAIWWSIAISSITKGLVSALFVRLTKKEVISLAEAV

Sequences:

>Translated_442_residues
MKTVDLTIGNVQRVILALALPLVGSSLLQFTYSLVDMFWVGALGSDAVASIGAASFYIMLGQAIQSLIVVGAGIKVSQAV
GRRDLNSVQRHVRASRRLNLTLGLSYASLLIMFGHTFIGFLNMGALAVEQLAYEYLFVSAPMLIFSFFNLLFARLFSAYG
NTTTAMRINATGVILNMILSPIFIYPFQLGVIGAALATLVANVMMFGLFWHRARTLFNWDEVVQPTRTDYKEIIRLGFPM
ATQRILFTVISIFLARMIGSYGTEAIAAQRIGLQIESIAYMMIGGLNGAMASYTGQNLGARKVDRVYEGYRVTTRLGMVY
TGFIMLFFLFVPDLLIGLFVDDVRTIEIGASYLRIIGISLVFSSIEMIGNGYFSGLGLPKIPATISIIFTVARIPLAFFL
EPYLGIDAIWWSIAISSITKGLVSALFVRLTKKEVISLAEAV
>Mature_442_residues
MKTVDLTIGNVQRVILALALPLVGSSLLQFTYSLVDMFWVGALGSDAVASIGAASFYIMLGQAIQSLIVVGAGIKVSQAV
GRRDLNSVQRHVRASRRLNLTLGLSYASLLIMFGHTFIGFLNMGALAVEQLAYEYLFVSAPMLIFSFFNLLFARLFSAYG
NTTTAMRINATGVILNMILSPIFIYPFQLGVIGAALATLVANVMMFGLFWHRARTLFNWDEVVQPTRTDYKEIIRLGFPM
ATQRILFTVISIFLARMIGSYGTEAIAAQRIGLQIESIAYMMIGGLNGAMASYTGQNLGARKVDRVYEGYRVTTRLGMVY
TGFIMLFFLFVPDLLIGLFVDDVRTIEIGASYLRIIGISLVFSSIEMIGNGYFSGLGLPKIPATISIIFTVARIPLAFFL
EPYLGIDAIWWSIAISSITKGLVSALFVRLTKKEVISLAEAV

Specific function: Multidrug efflux pump [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=308, Percent_Identity=25, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48499; Mature: 48499

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVDLTIGNVQRVILALALPLVGSSLLQFTYSLVDMFWVGALGSDAVASIGAASFYIML
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
GQAIQSLIVVGAGIKVSQAVGRRDLNSVQRHVRASRRLNLTLGLSYASLLIMFGHTFIGF
HHHHHHHHHHCCCCHHHHHHCHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHH
LNMGALAVEQLAYEYLFVSAPMLIFSFFNLLFARLFSAYGNTTTAMRINATGVILNMILS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHH
PIFIYPFQLGVIGAALATLVANVMMFGLFWHRARTLFNWDEVVQPTRTDYKEIIRLGFPM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHCCCH
ATQRILFTVISIFLARMIGSYGTEAIAAQRIGLQIESIAYMMIGGLNGAMASYTGQNLGA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHCCCCCCCH
RKVDRVYEGYRVTTRLGMVYTGFIMLFFLFVPDLLIGLFVDDVRTIEIGASYLRIIGISL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
VFSSIEMIGNGYFSGLGLPKIPATISIIFTVARIPLAFFLEPYLGIDAIWWSIAISSITK
HHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLVSALFVRLTKKEVISLAEAV
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTVDLTIGNVQRVILALALPLVGSSLLQFTYSLVDMFWVGALGSDAVASIGAASFYIML
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
GQAIQSLIVVGAGIKVSQAVGRRDLNSVQRHVRASRRLNLTLGLSYASLLIMFGHTFIGF
HHHHHHHHHHCCCCHHHHHHCHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHH
LNMGALAVEQLAYEYLFVSAPMLIFSFFNLLFARLFSAYGNTTTAMRINATGVILNMILS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHH
PIFIYPFQLGVIGAALATLVANVMMFGLFWHRARTLFNWDEVVQPTRTDYKEIIRLGFPM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHCCCH
ATQRILFTVISIFLARMIGSYGTEAIAAQRIGLQIESIAYMMIGGLNGAMASYTGQNLGA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHCCCCCCCH
RKVDRVYEGYRVTTRLGMVYTGFIMLFFLFVPDLLIGLFVDDVRTIEIGASYLRIIGISL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
VFSSIEMIGNGYFSGLGLPKIPATISIIFTVARIPLAFFLEPYLGIDAIWWSIAISSITK
HHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLVSALFVRLTKKEVISLAEAV
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]