Click here to switch to the map view.

The map label for this gene is murA2 [H]

Identifier: 229917073

GI number: 229917073

Start: 1316508

End: 1317764

Strand: Reverse

Name: murA2 [H]

Synonym: EAT1b_1347

Alternate gene names: 229917073

Gene position: 1317764-1316508 (Counterclockwise)

Preceding gene: 229917074

Following gene: 229917072

Centisome position: 43.93

GC content: 53.62

Gene sequence:

>1257_bases
GTGGAAATTCTCCATATCGTTGGGCAGCAAAAATTAGAAGGAACCGTCGAGATTAGCGGGGCGAAACAGAGTGCCCTCCC
TTGCCTTGTGGCTGCACTTCTCACGGAAGAGTCGGTGACGATTGAAAACGTTCCGATGATTGAAGATGTGGAAGTGATGG
TCAATTTGTTGAAAGAGCTCGGGGTTCGAGTCGAACGTGATGGCGAACGGACGACCATTCATTCGAATGAGGCGGTCGCC
ATGCCACTTCTCGGTTCTGAGACGCGGAAAGTCCGTGCCGCTGTCTACTTGCTCGGGGTCTTCGCGGCTCGCTTCGGAAA
AGGGGCGGTTGGGTTACCTGGAGGATATGCGATTGGTCCACGGCCGATTGACTTACATTTGAAAGCGTTGGAACGTCTCG
GCATTCACGTCGAGAATGAATCAGGTCTCTATCATGTCCGGGTCGATGAACTTGTCGGGAATCGAATTTACTTGGACTTG
CGGTCGTTTGGGGCAACCGTGAGTGCGATGCTTGCGGCTGTTTTAGCGACAGGGACGACGGTCATCGAAAACGCGGCCTG
CGACCCGGAAGTCGTCGATGTGGCTACGATGCTCACATCGATGGGGGCACATGTGAGTGGGGCCGGAACGGATGAGATTC
GAATCAAAGGGGTAGAGCGACTCCACGGTTGTACGCACACACTGATTCCGGATCGTCTCGAGGCCGGAACATTCATGATG
TTCGGTGCCGTATCTGGTCACGTGACCGTTCAACCGGTCATTCCGACACATCTCGAAGGGGTCATTCAAAAACTGTTGGA
CTTCGGAGCGGACGTCGAGGTCGGTGAAGAATCAATTACCGTGACGGCGAACCAATTCATGCCAACAGACATTCGTGTGT
TCCATTACTCAGGGTATCCGAGCGACTTGCAACCGGTGATGACGGCGGCCTTACTAAAAGCGGACGGAACGAGTGTCGTT
ACGGATAAATTGTATGCGCAACGATTCCGCCACATCGCCGAGATGCGACGGATGAATGCGCAAATCACTTTGGAAGATGC
GTCGGCTGTCATTCGTGGCGGGAATCAACTGGCGAACGCAGAGATGGAATGTACCGATGCACGGAGTGCTGCGGCCCTGG
TACTGTCGGCGCTCCAAGCATCTGGAGAATCGACGCTACTGCATGCAGAACGACTGAATGATTCGTATGTCGACTTTGTC
GGCAAATTAAAACAACTCGGTGCGCTCGTTTGGGTGGAGGAACATACCGAGGTATAA

Upstream 100 bases:

>100_bases
GATGAAACATCCGCTCACAGACAAAGGTATTGAGCAGTTCTTAGCGGATTGGAACAACGCTCAATCCAAATAAGTCCGTC
GTAGAAAGGTTTTGATCAGC

Downstream 100 bases:

>100_bases
AGGGGAGATTTCGGGTGGAACGAAGTTTATCGATGGAACTGGTTCGGGTGACAGAAGCTGCGGCACTTGCTTCAGCCCGT
TGGATGGGACGAGGATTAAA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2 [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MEILHIVGQQKLEGTVEISGAKQSALPCLVAALLTEESVTIENVPMIEDVEVMVNLLKELGVRVERDGERTTIHSNEAVA
MPLLGSETRKVRAAVYLLGVFAARFGKGAVGLPGGYAIGPRPIDLHLKALERLGIHVENESGLYHVRVDELVGNRIYLDL
RSFGATVSAMLAAVLATGTTVIENAACDPEVVDVATMLTSMGAHVSGAGTDEIRIKGVERLHGCTHTLIPDRLEAGTFMM
FGAVSGHVTVQPVIPTHLEGVIQKLLDFGADVEVGEESITVTANQFMPTDIRVFHYSGYPSDLQPVMTAALLKADGTSVV
TDKLYAQRFRHIAEMRRMNAQITLEDASAVIRGGNQLANAEMECTDARSAAALVLSALQASGESTLLHAERLNDSYVDFV
GKLKQLGALVWVEEHTEV

Sequences:

>Translated_418_residues
MEILHIVGQQKLEGTVEISGAKQSALPCLVAALLTEESVTIENVPMIEDVEVMVNLLKELGVRVERDGERTTIHSNEAVA
MPLLGSETRKVRAAVYLLGVFAARFGKGAVGLPGGYAIGPRPIDLHLKALERLGIHVENESGLYHVRVDELVGNRIYLDL
RSFGATVSAMLAAVLATGTTVIENAACDPEVVDVATMLTSMGAHVSGAGTDEIRIKGVERLHGCTHTLIPDRLEAGTFMM
FGAVSGHVTVQPVIPTHLEGVIQKLLDFGADVEVGEESITVTANQFMPTDIRVFHYSGYPSDLQPVMTAALLKADGTSVV
TDKLYAQRFRHIAEMRRMNAQITLEDASAVIRGGNQLANAEMECTDARSAAALVLSALQASGESTLLHAERLNDSYVDFV
GKLKQLGALVWVEEHTEV
>Mature_418_residues
MEILHIVGQQKLEGTVEISGAKQSALPCLVAALLTEESVTIENVPMIEDVEVMVNLLKELGVRVERDGERTTIHSNEAVA
MPLLGSETRKVRAAVYLLGVFAARFGKGAVGLPGGYAIGPRPIDLHLKALERLGIHVENESGLYHVRVDELVGNRIYLDL
RSFGATVSAMLAAVLATGTTVIENAACDPEVVDVATMLTSMGAHVSGAGTDEIRIKGVERLHGCTHTLIPDRLEAGTFMM
FGAVSGHVTVQPVIPTHLEGVIQKLLDFGADVEVGEESITVTANQFMPTDIRVFHYSGYPSDLQPVMTAALLKADGTSVV
TDKLYAQRFRHIAEMRRMNAQITLEDASAVIRGGNQLANAEMECTDARSAAALVLSALQASGESTLLHAERLNDSYVDFV
GKLKQLGALVWVEEHTEV

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=412, Percent_Identity=41.2621359223301, Blast_Score=304, Evalue=6e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 44940; Mature: 44940

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEILHIVGQQKLEGTVEISGAKQSALPCLVAALLTEESVTIENVPMIEDVEVMVNLLKEL
CCCEEECCCHHCCCEEEECCCCHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHH
GVRVERDGERTTIHSNEAVAMPLLGSETRKVRAAVYLLGVFAARFGKGAVGLPGGYAIGP
CCEEECCCCEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
RPIDLHLKALERLGIHVENESGLYHVRVDELVGNRIYLDLRSFGATVSAMLAAVLATGTT
CCHHHHHHHHHHCCCEEECCCCEEEEEHHHHHCCEEEEEHHHHCHHHHHHHHHHHHCCCH
VIENAACDPEVVDVATMLTSMGAHVSGAGTDEIRIKGVERLHGCTHTLIPDRLEAGTFMM
HHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECHHHHCCCHHHCCCCCCCCCCEEE
FGAVSGHVTVQPVIPTHLEGVIQKLLDFGADVEVGEESITVTANQFMPTDIRVFHYSGYP
EEECCCCEEEEECCCHHHHHHHHHHHHCCCCCEECCCEEEEEECCCCCCEEEEEEECCCC
SDLQPVMTAALLKADGTSVVTDKLYAQRFRHIAEMRRMNAQITLEDASAVIRGGNQLANA
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHCCCHHCCC
EMECTDARSAAALVLSALQASGESTLLHAERLNDSYVDFVGKLKQLGALVWVEEHTEV
CCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHCCCHHHHHHHHHHHCCEEEEEECCCCC
>Mature Secondary Structure
MEILHIVGQQKLEGTVEISGAKQSALPCLVAALLTEESVTIENVPMIEDVEVMVNLLKEL
CCCEEECCCHHCCCEEEECCCCHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHH
GVRVERDGERTTIHSNEAVAMPLLGSETRKVRAAVYLLGVFAARFGKGAVGLPGGYAIGP
CCEEECCCCEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
RPIDLHLKALERLGIHVENESGLYHVRVDELVGNRIYLDLRSFGATVSAMLAAVLATGTT
CCHHHHHHHHHHCCCEEECCCCEEEEEHHHHHCCEEEEEHHHHCHHHHHHHHHHHHCCCH
VIENAACDPEVVDVATMLTSMGAHVSGAGTDEIRIKGVERLHGCTHTLIPDRLEAGTFMM
HHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECHHHHCCCHHHCCCCCCCCCCEEE
FGAVSGHVTVQPVIPTHLEGVIQKLLDFGADVEVGEESITVTANQFMPTDIRVFHYSGYP
EEECCCCEEEEECCCHHHHHHHHHHHHCCCCCEECCCEEEEEECCCCCCEEEEEEECCCC
SDLQPVMTAALLKADGTSVVTDKLYAQRFRHIAEMRRMNAQITLEDASAVIRGGNQLANA
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHCCCHHCCC
EMECTDARSAAALVLSALQASGESTLLHAERLNDSYVDFVGKLKQLGALVWVEEHTEV
CCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHCCCHHHHHHHHHHHCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]