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The map label for this gene is iap [H]

Identifier: 229917069

GI number: 229917069

Start: 1313014

End: 1313709

Strand: Direct

Name: iap [H]

Synonym: EAT1b_1343

Alternate gene names: 229917069

Gene position: 1313014-1313709 (Clockwise)

Preceding gene: 229917058

Following gene: 229917079

Centisome position: 43.77

GC content: 46.12

Gene sequence:

>696_bases
ATGTTAAAGCGTATTGCATCAATCGTTGTCGCTGCCACTGTCGCTTTCTCGGGTCTTATGTTCTCAACAGGTGAACAAGC
AGAAGCCGCTACCGGTACATTTGCTTACTCGAAAGTAAACGGTTTGAACATCCGTACTGCCCCGTCACTTACGTCATCGA
AAGTCGTCGCGAAAATGGATAAAGGTCAACGCTATACATACCTTGGTAAATCCGGTTCGTTCTACAAAATCAACTACAAA
GGCACACACCGTTACATCTCAGCATCTTCAACGTATACGTACTTGAAAGCGAGCACGTCGACATCAACAACGGTTTCAAC
GTCATCTTCAAGCAAACGTTCGAAACTCGTCGCTGAATCGAAGAAATATCTCGGAACACCATATCGCTATGGCGGAACAA
CAACTGCAGGCTTTGACTGCTCAGGATATACTGGACACGTTTATAAGAAAGCAATCGGAAAAACACTTCCACGTTCTTCA
CGTCAGCAATACTCAAGCGCGAAGAAAATCTCGAAGTCATCGATCCAAGCGGGTGACCTCGTCTTCTTCTCACATTCAGG
CGGAACGATTCAACACGTTGGAATGGCACTTAGCAAAACACAAATGATCAACTCAGAAACAGGCGGCGTGAAATACGCGA
GCTTCACTTCTGGATACTGGGCACCACGCTACGTTGGCGCTGGATCATACCTTTAA

Upstream 100 bases:

>100_bases
AGGAAACCGGGTATATCTCGCAACTTGTGCTCTACCATAAAAATTACTCGATTTGTCATATACGAATGTCTTGATTTTAA
AAAACGGAGGGATTTACACA

Downstream 100 bases:

>100_bases
TACAACATCACGACTCGGTTCATCGGAACCGAGTCGTTTTATTTTTGCTTCAACGCCCCTCTCGCGTTCGTCGCCGCAAA
GACGATCATGAGCACGCTCA

Product: NLP/P60 protein

Products: NA

Alternate protein names: Invasion-associated protein [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MLKRIASIVVAATVAFSGLMFSTGEQAEAATGTFAYSKVNGLNIRTAPSLTSSKVVAKMDKGQRYTYLGKSGSFYKINYK
GTHRYISASSTYTYLKASTSTSTTVSTSSSSKRSKLVAESKKYLGTPYRYGGTTTAGFDCSGYTGHVYKKAIGKTLPRSS
RQQYSSAKKISKSSIQAGDLVFFSHSGGTIQHVGMALSKTQMINSETGGVKYASFTSGYWAPRYVGAGSYL

Sequences:

>Translated_231_residues
MLKRIASIVVAATVAFSGLMFSTGEQAEAATGTFAYSKVNGLNIRTAPSLTSSKVVAKMDKGQRYTYLGKSGSFYKINYK
GTHRYISASSTYTYLKASTSTSTTVSTSSSSKRSKLVAESKKYLGTPYRYGGTTTAGFDCSGYTGHVYKKAIGKTLPRSS
RQQYSSAKKISKSSIQAGDLVFFSHSGGTIQHVGMALSKTQMINSETGGVKYASFTSGYWAPRYVGAGSYL
>Mature_231_residues
MLKRIASIVVAATVAFSGLMFSTGEQAEAATGTFAYSKVNGLNIRTAPSLTSSKVVAKMDKGQRYTYLGKSGSFYKINYK
GTHRYISASSTYTYLKASTSTSTTVSTSSSSKRSKLVAESKKYLGTPYRYGGTTTAGFDCSGYTGHVYKKAIGKTLPRSS
RQQYSSAKKISKSSIQAGDLVFFSHSGGTIQHVGMALSKTQMINSETGGVKYASFTSGYWAPRYVGAGSYL

Specific function: This major extracellular protein may be involved in the invasion of non-professional phagocytic cells by Listeria [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1788501, Length=120, Percent_Identity=35, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1787944, Length=110, Percent_Identity=38.1818181818182, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1788001, Length=114, Percent_Identity=37.719298245614, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786421, Length=117, Percent_Identity=32.4786324786325, Blast_Score=71, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482
- InterPro:   IPR003646
- InterPro:   IPR013247 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60; PF08239 SH3_3 [H]

EC number: NA

Molecular weight: Translated: 24717; Mature: 24717

Theoretical pI: Translated: 10.55; Mature: 10.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRIASIVVAATVAFSGLMFSTGEQAEAATGTFAYSKVNGLNIRTAPSLTSSKVVAKMD
CHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEEEEEECCCEEEECCCCCCCHHEEECC
KGQRYTYLGKSGSFYKINYKGTHRYISASSTYTYLKASTSTSTTVSTSSSSKRSKLVAES
CCCEEEEECCCCCEEEEEECCCEEEEECCCEEEEEEECCCCCEEEECCCCCHHHHHHHHH
KKYLGTPYRYGGTTTAGFDCSGYTGHVYKKAIGKTLPRSSRQQYSSAKKISKSSIQAGDL
HHHCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCE
VFFSHSGGTIQHVGMALSKTQMINSETGGVKYASFTSGYWAPRYVGAGSYL
EEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEECCCCCCC
>Mature Secondary Structure
MLKRIASIVVAATVAFSGLMFSTGEQAEAATGTFAYSKVNGLNIRTAPSLTSSKVVAKMD
CHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEEEEEECCCEEEECCCCCCCHHEEECC
KGQRYTYLGKSGSFYKINYKGTHRYISASSTYTYLKASTSTSTTVSTSSSSKRSKLVAES
CCCEEEEECCCCCEEEEEECCCEEEEECCCEEEEEEECCCCCEEEECCCCCHHHHHHHHH
KKYLGTPYRYGGTTTAGFDCSGYTGHVYKKAIGKTLPRSSRQQYSSAKKISKSSIQAGDL
HHHCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCE
VFFSHSGGTIQHVGMALSKTQMINSETGGVKYASFTSGYWAPRYVGAGSYL
EEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1514809; 1459966 [H]