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The map label for this gene is tdk [H]

Identifier: 229917065

GI number: 229917065

Start: 1308928

End: 1309539

Strand: Reverse

Name: tdk [H]

Synonym: EAT1b_1339

Alternate gene names: 229917065

Gene position: 1309539-1308928 (Counterclockwise)

Preceding gene: 229917066

Following gene: 229917064

Centisome position: 43.65

GC content: 52.45

Gene sequence:

>612_bases
ATGATGCATGTGACGAACCGATATGGTTGGATTGAAGTGATTTGTGGGAGTATGTTTTCGGGGAAGTCGGAGGAATTGAT
TCGCCGAGTCCGCCGTGCTCATTATGGAAAGATTCCGGTCCAAGTGTTCAAACCAGCAATCGACGACCGGTATCATGAAG
AGAACGTCGTCTCACACACAGGGAACTCGGTCGTGGCCGTGCCGATCGCATCGAGCCAAGAATTATATGATGCTGTACGT
GAAGAAACACAGGTCATCGCGATTGATGAGGTACAATTCTTTGATGAGGGAATTGTGGACGTCATCGAACAACTTGCGAA
CGAAGACAAACGCGTCATCTGCGCCGGGCTCGACATGGACTTTCGGGGCGAACCGTTCACGATGATGCCTGAACTGTTGT
CACGCGCGGAGTTCGTGACGAAACTACAGGCAATCTGTTTATCATGCGGCGCGCCTGCTTCACGGACACAGCGTCTGATT
GACGGGCAACCGGCTCGGTATGAGGACCCGGTCATCTTGGTCGGGGCTTCCGAGTCTTACGAACCACGATGCCGACATTG
TCATGATGTACCGAATAAACCACATCCGGTCCGCCATACGGTGGTAGACTGA

Upstream 100 bases:

>100_bases
GAGTTCTTTCAATCAGCATTTAGGAGAAGTCAACCCTTTTCCTCAACTCGAAAGATAGGTATAATCGGAAAGCGATTATC
GATGGAGAGGGCGAAGAACA

Downstream 100 bases:

>100_bases
TGAATCGACGGACCGCCCTCGGCGGTCCGTTTTTTTGCTATAATAGATAGAGTTTGATTTGACGGAGAAAGGACGGATCA
TCATGTTTGACCGTTTAAGT

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MMHVTNRYGWIEVICGSMFSGKSEELIRRVRRAHYGKIPVQVFKPAIDDRYHEENVVSHTGNSVVAVPIASSQELYDAVR
EETQVIAIDEVQFFDEGIVDVIEQLANEDKRVICAGLDMDFRGEPFTMMPELLSRAEFVTKLQAICLSCGAPASRTQRLI
DGQPARYEDPVILVGASESYEPRCRHCHDVPNKPHPVRHTVVD

Sequences:

>Translated_203_residues
MMHVTNRYGWIEVICGSMFSGKSEELIRRVRRAHYGKIPVQVFKPAIDDRYHEENVVSHTGNSVVAVPIASSQELYDAVR
EETQVIAIDEVQFFDEGIVDVIEQLANEDKRVICAGLDMDFRGEPFTMMPELLSRAEFVTKLQAICLSCGAPASRTQRLI
DGQPARYEDPVILVGASESYEPRCRHCHDVPNKPHPVRHTVVD
>Mature_203_residues
MMHVTNRYGWIEVICGSMFSGKSEELIRRVRRAHYGKIPVQVFKPAIDDRYHEENVVSHTGNSVVAVPIASSQELYDAVR
EETQVIAIDEVQFFDEGIVDVIEQLANEDKRVICAGLDMDFRGEPFTMMPELLSRAEFVTKLQAICLSCGAPASRTQRLI
DGQPARYEDPVILVGASESYEPRCRHCHDVPNKPHPVRHTVVD

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Homo sapiens, GI164698438, Length=182, Percent_Identity=40.1098901098901, Blast_Score=108, Evalue=4e-24,
Organism=Escherichia coli, GI1787490, Length=178, Percent_Identity=32.0224719101124, Blast_Score=72, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17543396, Length=188, Percent_Identity=34.0425531914894, Blast_Score=94, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 22937; Mature: 22937

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMHVTNRYGWIEVICGSMFSGKSEELIRRVRRAHYGKIPVQVFKPAIDDRYHEENVVSHT
CCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHCCHHHHHHCHHHHHHCC
GNSVVAVPIASSQELYDAVREETQVIAIDEVQFFDEGIVDVIEQLANEDKRVICAGLDMD
CCEEEEEECCCCHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
FRGEPFTMMPELLSRAEFVTKLQAICLSCGAPASRTQRLIDGQPARYEDPVILVGASESY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCEEEEECCCCC
EPRCRHCHDVPNKPHPVRHTVVD
CCHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MMHVTNRYGWIEVICGSMFSGKSEELIRRVRRAHYGKIPVQVFKPAIDDRYHEENVVSHT
CCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHCCHHHHHHCHHHHHHCC
GNSVVAVPIASSQELYDAVREETQVIAIDEVQFFDEGIVDVIEQLANEDKRVICAGLDMD
CCEEEEEECCCCHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
FRGEPFTMMPELLSRAEFVTKLQAICLSCGAPASRTQRLIDGQPARYEDPVILVGASESY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCEEEEECCCCC
EPRCRHCHDVPNKPHPVRHTVVD
CCHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]