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The map label for this gene is yeaP [H]

Identifier: 229917010

GI number: 229917010

Start: 1261064

End: 1262002

Strand: Reverse

Name: yeaP [H]

Synonym: EAT1b_1284

Alternate gene names: 229917010

Gene position: 1262002-1261064 (Counterclockwise)

Preceding gene: 229917011

Following gene: 229917008

Centisome position: 42.07

GC content: 42.17

Gene sequence:

>939_bases
ATGCACTCATATGAGTTTCAAATGTATCGGAATTTCGATGAGCTAGCGATTGACTTGATTGAGTTAGCAAAAGAAATAGT
ACCAGATAAACTAGTCTATCTCACGTCAATTGAGAATGACACCCAACATATACTCAAACTGTCCTCACAAGATTCTCCTA
TCCTACTTGAAGAAGGCATGTCCTTTGATTTGAAGGATACGGTATGTAATCGAATCGATTTCAATCAACGAGAAGTTTTG
ATGTATGAAGACATTGAGTCGCAGATTGAATCGACGCGACTTCAGTCATTACTGCGCGAAGTGAACATCAAGTCGTATTT
GGGAATCCCGATTCTGACGAAGAACGGGGATATTTTCGGTACGCTCTGTGTCGCCAATCATAAAAGCGCCCAGTACGATT
CAAAAAGTGTCCGCTTGTTGAAGCGCGTGGTTCGTATGTTCAGTTACTATTTAGAACTCGAACGTCGTGCCTCACGGGAC
GAGTTGACGAATCTTTATAATCGACATTACTTGTCTAACTATTTTGAGACGAATCCGAATCAAGGTGGGGCACTGTTTTT
AATTGATTTAGATGGGTTCAAATGGGTGAATGACACATTCGGTCATGATGAAGGGGACCTTGTCCTAAAAGAAGTGGCGC
TTCGTCTGAGACGTTTGATGGAGCCGATACCTGATTCGAGAGTGTATCGTTTAGGTGGGGATGAATTTCTTATAAAAATC
GCAGATGCGTTATCCAAAGAGACTGTCATTGGGTATGCTGAACAAATCTTGTCTGTATTGAAAGAATGGGACGACCATCT
CCCGTTATCAACGAGCATCGGCATCGCTCAATATGATTCCGACGAACAGGCGGACCTCGGTCGATTGTTGAAAGAGGCAG
ACATTGCACTGTATCAATCTAAATCGAGCGGGAAAAACACGTACAAGTTTTATAAATAA

Upstream 100 bases:

>100_bases
CGCGATGAACGTCGTGAGGTATTTTTTATATATCGGTACAGGGAAAGACCAAACTGTTCGATATAATGAGTGTGGATGAT
TTTTAGCGTGGAGGTACCAT

Downstream 100 bases:

>100_bases
CGTCAGAAGGCTAAACCGATGGATTACGATTGGTTTAGCCTTCTGTTTTCGCATTCAGCACCAACGAACCGATTGGCGTG
AAAGGATCGAATGAAAAACG

Product: diguanylate cyclase with GAF sensor

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MHSYEFQMYRNFDELAIDLIELAKEIVPDKLVYLTSIENDTQHILKLSSQDSPILLEEGMSFDLKDTVCNRIDFNQREVL
MYEDIESQIESTRLQSLLREVNIKSYLGIPILTKNGDIFGTLCVANHKSAQYDSKSVRLLKRVVRMFSYYLELERRASRD
ELTNLYNRHYLSNYFETNPNQGGALFLIDLDGFKWVNDTFGHDEGDLVLKEVALRLRRLMEPIPDSRVYRLGGDEFLIKI
ADALSKETVIGYAEQILSVLKEWDDHLPLSTSIGIAQYDSDEQADLGRLLKEADIALYQSKSSGKNTYKFYK

Sequences:

>Translated_312_residues
MHSYEFQMYRNFDELAIDLIELAKEIVPDKLVYLTSIENDTQHILKLSSQDSPILLEEGMSFDLKDTVCNRIDFNQREVL
MYEDIESQIESTRLQSLLREVNIKSYLGIPILTKNGDIFGTLCVANHKSAQYDSKSVRLLKRVVRMFSYYLELERRASRD
ELTNLYNRHYLSNYFETNPNQGGALFLIDLDGFKWVNDTFGHDEGDLVLKEVALRLRRLMEPIPDSRVYRLGGDEFLIKI
ADALSKETVIGYAEQILSVLKEWDDHLPLSTSIGIAQYDSDEQADLGRLLKEADIALYQSKSSGKNTYKFYK
>Mature_312_residues
MHSYEFQMYRNFDELAIDLIELAKEIVPDKLVYLTSIENDTQHILKLSSQDSPILLEEGMSFDLKDTVCNRIDFNQREVL
MYEDIESQIESTRLQSLLREVNIKSYLGIPILTKNGDIFGTLCVANHKSAQYDSKSVRLLKRVVRMFSYYLELERRASRD
ELTNLYNRHYLSNYFETNPNQGGALFLIDLDGFKWVNDTFGHDEGDLVLKEVALRLRRLMEPIPDSRVYRLGGDEFLIKI
ADALSKETVIGYAEQILSVLKEWDDHLPLSTSIGIAQYDSDEQADLGRLLKEADIALYQSKSSGKNTYKFYK

Specific function: Catalyzes the condensation of two GTP molecules to the cyclic dinucleotide di-GMP (c-di-GMP), which acts as a secondary messenger (Probable). Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87081977, Length=326, Percent_Identity=27.6073619631902, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787056, Length=167, Percent_Identity=37.125748502994, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI145693134, Length=166, Percent_Identity=34.9397590361446, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI87081881, Length=165, Percent_Identity=35.7575757575758, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787262, Length=195, Percent_Identity=28.7179487179487, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788381, Length=183, Percent_Identity=31.1475409836066, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787541, Length=172, Percent_Identity=31.9767441860465, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1786584, Length=238, Percent_Identity=29.8319327731092, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788956, Length=172, Percent_Identity=34.8837209302326, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787816, Length=199, Percent_Identity=30.6532663316583, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787802, Length=166, Percent_Identity=29.5180722891566, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR003018 [H]

Pfam domain/function: PF01590 GAF; PF00990 GGDEF [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 36112; Mature: 36112

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSYEFQMYRNFDELAIDLIELAKEIVPDKLVYLTSIENDTQHILKLSSQDSPILLEEGM
CCCCHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCCEEEECCC
SFDLKDTVCNRIDFNQREVLMYEDIESQIESTRLQSLLREVNIKSYLGIPILTKNGDIFG
CCCHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEECCCCEEE
TLCVANHKSAQYDSKSVRLLKRVVRMFSYYLELERRASRDELTNLYNRHYLSNYFETNPN
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCC
QGGALFLIDLDGFKWVNDTFGHDEGDLVLKEVALRLRRLMEPIPDSRVYRLGGDEFLIKI
CCCEEEEEECCCCEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHH
ADALSKETVIGYAEQILSVLKEWDDHLPLSTSIGIAQYDSDEQADLGRLLKEADIALYQS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHEEC
KSSGKNTYKFYK
CCCCCCCCCCCC
>Mature Secondary Structure
MHSYEFQMYRNFDELAIDLIELAKEIVPDKLVYLTSIENDTQHILKLSSQDSPILLEEGM
CCCCHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCCEEEECCC
SFDLKDTVCNRIDFNQREVLMYEDIESQIESTRLQSLLREVNIKSYLGIPILTKNGDIFG
CCCHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEECCCCEEE
TLCVANHKSAQYDSKSVRLLKRVVRMFSYYLELERRASRDELTNLYNRHYLSNYFETNPN
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCC
QGGALFLIDLDGFKWVNDTFGHDEGDLVLKEVALRLRRLMEPIPDSRVYRLGGDEFLIKI
CCCEEEEEECCCCEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHH
ADALSKETVIGYAEQILSVLKEWDDHLPLSTSIGIAQYDSDEQADLGRLLKEADIALYQS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHEEC
KSSGKNTYKFYK
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]