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The map label for this gene is licH [H]

Identifier: 229916867

GI number: 229916867

Start: 1110266

End: 1111585

Strand: Direct

Name: licH [H]

Synonym: EAT1b_1140

Alternate gene names: 229916867

Gene position: 1110266-1111585 (Clockwise)

Preceding gene: 229916860

Following gene: 229916868

Centisome position: 37.01

GC content: 54.7

Gene sequence:

>1320_bases
ATGGCAGTCAAGGTCGTCATCATCGGCGGTGGGTCCAGTTACACCCCGGAAATCATCGAAGGATTGATTGATCGACAGGC
AACGTTCCCCGTTCGGGAGATCGTGCTCGTCGATATCGAAGAAGGGAGGGAGAAACTAGAGATCGTCGGTCGCCTCGCTC
AGCGGATGATTGAGAAGGCAAACGCCGAAATCACACTCAGTTGGACGCTCAATCGAAGAGCCGCACTCGTCGGCGCAGAT
TTTGTATCCACACAGATTCGGGTCGGTGGACTCAAGGCACGCGCGCTCGATGAACGCATCCCGCTCAAGCACGGCTTCAT
CGGGCAAGAGACGAATGGCGCAGGCGGATTATTCAAAGCGTTCCGTACCATCCCGGTCTTGATCGACTTGGCAAATGAAG
TCGCCGAGATTTGTCCGGATGCCTGGCTCGTCAACTTCACCAATCCGGCGGGCATCGTCACCGAGGCCGTACTCAAGCAC
TCATCTCATAAGAAGGTCATCGGTGTATGCAACATCCCGTTCAACATGCGAAACTCGGTCGCTGAGATCCTCGAGACGCC
TGTCGAACGAGTCGCGATTGAATTTATCGGATTGAACCACTTCGTCTTCGGTCGTCACGTATGGGTCGACGGCGTGGACC
GGACGAGTGACGTCCTCGCCTCGCTCAACGCAGGCAATGACTACTCGCCGGCGAACATCGTCGGTCTCGGTTGGAGCGAA
TCGTTCCTATCGTCACTCGGCATGTTACCGAACCCGTATCACCAGTATTACTTCCAGACGAAAGATGTGTTGAAGAAAGA
TCTCGAGGCGTATGCACAAAATGGCACCCGTGCCGAAGTCGTGCAACAAGTCGAGGCACAGTTGTTCGAGAAATACAAAG
ACGTCGATCTCGCCGTCAAACCGGAAGAGCTTGAAAAACGTGGAGGCGCCTACTATTCAGACGCCGCCTGCAACTTGATG
GACTCGATTCACAACGACCGCGGTGACATCCAGACGGTCAACACGCTCAATCACGGCACGATTCGAGATTTACCAGACGA
CGCGGTCATCGAAGTGAACGCCGTCATCACGAAGTCGGGGCCTCGCCCAATCTCCATCGGCGCGTTGCCGCTACCGATTC
GTGGGCTTATCACGAATTTAAAAACGTTTGAACAGCTCGCCATCCAAGCGGCTGTATCTGGCACGTATGAGGACGCCTAC
CTTGCCTGCCTCATGAACCCGCTCATTCAAGACGAGAAACGGATCGACCCGCTTCTTAAAGAGCTGTTCACAGCGCACGA
GGCGTACCTACCCCAATTCAAGAAGGAGGTTTACTCATGA

Upstream 100 bases:

>100_bases
TATTTGTATTATTTGTATTTTTTATATTGCGGTAAGTTGTATCATTTGTTATATTTGTTACGACAAAAAGAAATCGCTTT
CAAAAGGAGGAGTTGGCACC

Downstream 100 bases:

>100_bases
ACAAGTTTATTGAAATCGCGGGACGCATTGGGTCCCAAAGGCACTTAGTCGCCATCCGTGACGGATTCGTTTCCGTCATG
CCACTCATCATCGTCGGGTC

Product: glycoside hydrolase family 4

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MAVKVVIIGGGSSYTPEIIEGLIDRQATFPVREIVLVDIEEGREKLEIVGRLAQRMIEKANAEITLSWTLNRRAALVGAD
FVSTQIRVGGLKARALDERIPLKHGFIGQETNGAGGLFKAFRTIPVLIDLANEVAEICPDAWLVNFTNPAGIVTEAVLKH
SSHKKVIGVCNIPFNMRNSVAEILETPVERVAIEFIGLNHFVFGRHVWVDGVDRTSDVLASLNAGNDYSPANIVGLGWSE
SFLSSLGMLPNPYHQYYFQTKDVLKKDLEAYAQNGTRAEVVQQVEAQLFEKYKDVDLAVKPEELEKRGGAYYSDAACNLM
DSIHNDRGDIQTVNTLNHGTIRDLPDDAVIEVNAVITKSGPRPISIGALPLPIRGLITNLKTFEQLAIQAAVSGTYEDAY
LACLMNPLIQDEKRIDPLLKELFTAHEAYLPQFKKEVYS

Sequences:

>Translated_439_residues
MAVKVVIIGGGSSYTPEIIEGLIDRQATFPVREIVLVDIEEGREKLEIVGRLAQRMIEKANAEITLSWTLNRRAALVGAD
FVSTQIRVGGLKARALDERIPLKHGFIGQETNGAGGLFKAFRTIPVLIDLANEVAEICPDAWLVNFTNPAGIVTEAVLKH
SSHKKVIGVCNIPFNMRNSVAEILETPVERVAIEFIGLNHFVFGRHVWVDGVDRTSDVLASLNAGNDYSPANIVGLGWSE
SFLSSLGMLPNPYHQYYFQTKDVLKKDLEAYAQNGTRAEVVQQVEAQLFEKYKDVDLAVKPEELEKRGGAYYSDAACNLM
DSIHNDRGDIQTVNTLNHGTIRDLPDDAVIEVNAVITKSGPRPISIGALPLPIRGLITNLKTFEQLAIQAAVSGTYEDAY
LACLMNPLIQDEKRIDPLLKELFTAHEAYLPQFKKEVYS
>Mature_438_residues
AVKVVIIGGGSSYTPEIIEGLIDRQATFPVREIVLVDIEEGREKLEIVGRLAQRMIEKANAEITLSWTLNRRAALVGADF
VSTQIRVGGLKARALDERIPLKHGFIGQETNGAGGLFKAFRTIPVLIDLANEVAEICPDAWLVNFTNPAGIVTEAVLKHS
SHKKVIGVCNIPFNMRNSVAEILETPVERVAIEFIGLNHFVFGRHVWVDGVDRTSDVLASLNAGNDYSPANIVGLGWSES
FLSSLGMLPNPYHQYYFQTKDVLKKDLEAYAQNGTRAEVVQQVEAQLFEKYKDVDLAVKPEELEKRGGAYYSDAACNLMD
SIHNDRGDIQTVNTLNHGTIRDLPDDAVIEVNAVITKSGPRPISIGALPLPIRGLITNLKTFEQLAIQAAVSGTYEDAYL
ACLMNPLIQDEKRIDPLLKELFTAHEAYLPQFKKEVYS

Specific function: Hydrolyzes phospho-beta-glucosides (Probable) [H]

COG id: COG1486

COG function: function code G; Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1788029, Length=436, Percent_Identity=47.9357798165138, Blast_Score=411, Evalue=1e-116,
Organism=Escherichia coli, GI1790560, Length=457, Percent_Identity=25.382932166302, Blast_Score=119, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019802
- InterPro:   IPR001088
- InterPro:   IPR022616
- InterPro:   IPR015955
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02056 Glyco_hydro_4; PF11975 Glyco_hydro_4C [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 48454; Mature: 48323

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS01324 GLYCOSYL_HYDROL_F4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVKVVIIGGGSSYTPEIIEGLIDRQATFPVREIVLVDIEEGREKLEIVGRLAQRMIEKA
CEEEEEEECCCCCCCHHHHHHHHCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHC
NAEITLSWTLNRRAALVGADFVSTQIRVGGLKARALDERIPLKHGFIGQETNGAGGLFKA
CCEEEEEEEECCCEEEEECHHHHCEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHH
FRTIPVLIDLANEVAEICPDAWLVNFTNPAGIVTEAVLKHSSHKKVIGVCNIPFNMRNSV
HHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHH
AEILETPVERVAIEFIGLNHFVFGRHVWVDGVDRTSDVLASLNAGNDYSPANIVGLGWSE
HHHHHCHHHHHHHHHCCCCCEEECCEEEECCCCHHHHHHHHCCCCCCCCCCCEEECCCCH
SFLSSLGMLPNPYHQYYFQTKDVLKKDLEAYAQNGTRAEVVQQVEAQLFEKYKDVDLAVK
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEC
PEELEKRGGAYYSDAACNLMDSIHNDRGDIQTVNTLNHGTIRDLPDDAVIEVNAVITKSG
HHHHHHCCCCEECHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCEEEEEEEEECCC
PRPISIGALPLPIRGLITNLKTFEQLAIQAAVSGTYEDAYLACLMNPLIQDEKRIDPLLK
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHH
ELFTAHEAYLPQFKKEVYS
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AVKVVIIGGGSSYTPEIIEGLIDRQATFPVREIVLVDIEEGREKLEIVGRLAQRMIEKA
EEEEEEECCCCCCCHHHHHHHHCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHC
NAEITLSWTLNRRAALVGADFVSTQIRVGGLKARALDERIPLKHGFIGQETNGAGGLFKA
CCEEEEEEEECCCEEEEECHHHHCEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHH
FRTIPVLIDLANEVAEICPDAWLVNFTNPAGIVTEAVLKHSSHKKVIGVCNIPFNMRNSV
HHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHH
AEILETPVERVAIEFIGLNHFVFGRHVWVDGVDRTSDVLASLNAGNDYSPANIVGLGWSE
HHHHHCHHHHHHHHHCCCCCEEECCEEEECCCCHHHHHHHHCCCCCCCCCCCEEECCCCH
SFLSSLGMLPNPYHQYYFQTKDVLKKDLEAYAQNGTRAEVVQQVEAQLFEKYKDVDLAVK
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEC
PEELEKRGGAYYSDAACNLMDSIHNDRGDIQTVNTLNHGTIRDLPDDAVIEVNAVITKSG
HHHHHHCCCCEECHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCEEEEEEEEECCC
PRPISIGALPLPIRGLITNLKTFEQLAIQAAVSGTYEDAYLACLMNPLIQDEKRIDPLLK
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHH
ELFTAHEAYLPQFKKEVYS
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8990303; 9384377; 8969509 [H]