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The map label for this gene is ygbD [C]

Identifier: 229916751

GI number: 229916751

Start: 971418

End: 973076

Strand: Reverse

Name: ygbD [C]

Synonym: EAT1b_1024

Alternate gene names: 229916751

Gene position: 973076-971418 (Counterclockwise)

Preceding gene: 229916752

Following gene: 229916750

Centisome position: 32.44

GC content: 55.33

Gene sequence:

>1659_bases
ATGAAACTAGTCATCATTGGTTCAGTCGCTGCTGGGACATCGGTTGCGGCGAAAGCGCGTCGGAACAACGAAGACGCACA
AATCACGATTTACGATCGGGATTACGATATCTCGTACTCTGGTTGTGGGATTCCATACTACGTTGGCGGAGAAGTCGAGT
CACGTGACGATCTGACACCGCGCGATGCGGCCTTCTTCAAGAAGCGCTACAACATCGACGTCATGACACGCCATAACGTC
ACAGCTGTCGACAAAGACGCGAAGACGGTGACGGTTGAAAACTTAGAGACGGGTGACACGTTCACGGACGCCTATGACGT
CCTCGTCCTTGCGACGGGTGCGTCGAGCATCATCCCACCGATTCCAGGGGTGAAGTCGGACAACGTCTTCCCGATTCGAA
ACATCCAACATGCGGAGGCGACACGCTCCTTCGTCGATTCGACAGACCCGAAACATGCGACAATCATCGGAGCCGGCTTC
ATCGGTCTAGAGATGGCGGAACAGTTGAAGCTTCGTGGTGTGGACGTGACCATCATCGAACGTGTACCGCAAGTGATGCC
ACCACTCGACAAGGATATGGCGTGTCGCGTTGAGGAACACCTCGAGAAGAATGGAATCGAGCTCATGCTCGGAGAGACCG
TGACAGAACTTGTCGGCGACGGACATGTCGAACGGGTCGTCACGGAGAGCGGGAAGACGATTGAGACCGACTTCGTCATC
TTGTCTGTGGGAGTCCGTCCGAACGTCGAGCTCGCCATGAACATGGGAGTCAAACTGGGTGAAACGGGTGCAATCGCCGT
CAATGAGCGGATGGAGACAAACATCCCAGACGTCTATGCGGCAGGAGACGTCGCGGAGAGCTTCTCAATCGTGACAGGGA
AACCGATTTGGCGTCCACTCGGTTCGACAGCGAACAAGATGGGACGGACCGCCGGGGACGTCATCACGGGCGGTCACCTC
GAACATCGGGGCATCCTCGGCACAGGCATCTTCAAAGTGTTCGGACTTGCTGTCGCACAGACGGGTCTCGCCGAAAAAGA
AGCACGTGAACTCGGATACGATATCGAGGTACTTCATAATACGAAACCGGATAAGCCTGCCTATATGGGTGGGAAAGATA
TGACGATTAAAGCGGTCGCCGACCGTGCGACACGTCAACTGCTCGGCGTCCAAATCGTCGGATTTGAAGGAGTCGACAAA
CGGATCGACGTCTTCGTCACGGCCATCACCCTCAAGGCGAAAGTCGACGACTTGTTCCATCTCGACCTCGCCTACGCACC
ACCGTTCTCGACGACGAAAGACCCGGTCATGTATACGGGGATGGTCCTCGCGAACAGTATCGACAAGGCGGCGCGACTCA
TCACACCGGCCGAACTTCAGGCACGAATCGATGCCGGGGAAGACATGCAAATCATCGATACGCGGAAAGCTTCACAGTTC
GAGAAGGCGTGTGTCGATTGTGCGGTCAACGTCCCACTCGGCAACCTCCGGGAAGCGGCGAAAGACATGGACAAGGACAA
ACCGACCGTCGTCTACTGTAACGGTGGGGTGACGGGGAACGCGGCCCAGAACGTGCTCCGTAACCTCGGATTCACTGACG
TGTACAACTTGTCAGGTGGAAATAAGAACTATCAGTTGTTCAAAAAATACGGGAACTGA

Upstream 100 bases:

>100_bases
AGTATTTCAAAATCGGGATCATCTTGACGATTCCGACATTGGCTATCACGTTGCTCGGCCTATACATCAGCTTATTACTT
TATTGAGGAGTGGATTATAT

Downstream 100 bases:

>100_bases
GCAAGACGACGTCCATTGCGGGCGTCGTTTTTTGATATGCTGGACGTGAGGTGAAGCGGATGGATTATAAGATGTTACAT
GAGAAGTTTGAGCGACGGAA

Product: pyridine nucleotide-disulphide oxidoreductase dimerisation region

Products: NA

Alternate protein names: NOXase [H]

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MKLVIIGSVAAGTSVAAKARRNNEDAQITIYDRDYDISYSGCGIPYYVGGEVESRDDLTPRDAAFFKKRYNIDVMTRHNV
TAVDKDAKTVTVENLETGDTFTDAYDVLVLATGASSIIPPIPGVKSDNVFPIRNIQHAEATRSFVDSTDPKHATIIGAGF
IGLEMAEQLKLRGVDVTIIERVPQVMPPLDKDMACRVEEHLEKNGIELMLGETVTELVGDGHVERVVTESGKTIETDFVI
LSVGVRPNVELAMNMGVKLGETGAIAVNERMETNIPDVYAAGDVAESFSIVTGKPIWRPLGSTANKMGRTAGDVITGGHL
EHRGILGTGIFKVFGLAVAQTGLAEKEARELGYDIEVLHNTKPDKPAYMGGKDMTIKAVADRATRQLLGVQIVGFEGVDK
RIDVFVTAITLKAKVDDLFHLDLAYAPPFSTTKDPVMYTGMVLANSIDKAARLITPAELQARIDAGEDMQIIDTRKASQF
EKACVDCAVNVPLGNLREAAKDMDKDKPTVVYCNGGVTGNAAQNVLRNLGFTDVYNLSGGNKNYQLFKKYGN

Sequences:

>Translated_552_residues
MKLVIIGSVAAGTSVAAKARRNNEDAQITIYDRDYDISYSGCGIPYYVGGEVESRDDLTPRDAAFFKKRYNIDVMTRHNV
TAVDKDAKTVTVENLETGDTFTDAYDVLVLATGASSIIPPIPGVKSDNVFPIRNIQHAEATRSFVDSTDPKHATIIGAGF
IGLEMAEQLKLRGVDVTIIERVPQVMPPLDKDMACRVEEHLEKNGIELMLGETVTELVGDGHVERVVTESGKTIETDFVI
LSVGVRPNVELAMNMGVKLGETGAIAVNERMETNIPDVYAAGDVAESFSIVTGKPIWRPLGSTANKMGRTAGDVITGGHL
EHRGILGTGIFKVFGLAVAQTGLAEKEARELGYDIEVLHNTKPDKPAYMGGKDMTIKAVADRATRQLLGVQIVGFEGVDK
RIDVFVTAITLKAKVDDLFHLDLAYAPPFSTTKDPVMYTGMVLANSIDKAARLITPAELQARIDAGEDMQIIDTRKASQF
EKACVDCAVNVPLGNLREAAKDMDKDKPTVVYCNGGVTGNAAQNVLRNLGFTDVYNLSGGNKNYQLFKKYGN
>Mature_552_residues
MKLVIIGSVAAGTSVAAKARRNNEDAQITIYDRDYDISYSGCGIPYYVGGEVESRDDLTPRDAAFFKKRYNIDVMTRHNV
TAVDKDAKTVTVENLETGDTFTDAYDVLVLATGASSIIPPIPGVKSDNVFPIRNIQHAEATRSFVDSTDPKHATIIGAGF
IGLEMAEQLKLRGVDVTIIERVPQVMPPLDKDMACRVEEHLEKNGIELMLGETVTELVGDGHVERVVTESGKTIETDFVI
LSVGVRPNVELAMNMGVKLGETGAIAVNERMETNIPDVYAAGDVAESFSIVTGKPIWRPLGSTANKMGRTAGDVITGGHL
EHRGILGTGIFKVFGLAVAQTGLAEKEARELGYDIEVLHNTKPDKPAYMGGKDMTIKAVADRATRQLLGVQIVGFEGVDK
RIDVFVTAITLKAKVDDLFHLDLAYAPPFSTTKDPVMYTGMVLANSIDKAARLITPAELQARIDAGEDMQIIDTRKASQF
EKACVDCAVNVPLGNLREAAKDMDKDKPTVVYCNGGVTGNAAQNVLRNLGFTDVYNLSGGNKNYQLFKKYGN

Specific function: Catalyzes the four-electron reduction of molecular oxygen to water [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=323, Percent_Identity=28.4829721362229, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI65787454, Length=323, Percent_Identity=28.4829721362229, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI226437568, Length=323, Percent_Identity=28.4829721362229, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI91199540, Length=387, Percent_Identity=25.3229974160207, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1789065, Length=308, Percent_Identity=27.2727272727273, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1789765, Length=402, Percent_Identity=25.1243781094527, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1788892, Length=227, Percent_Identity=26.8722466960352, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87082354, Length=254, Percent_Identity=26.7716535433071, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1786307, Length=323, Percent_Identity=27.2445820433437, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87081717, Length=301, Percent_Identity=25.5813953488372, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789915, Length=366, Percent_Identity=25.1366120218579, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17559934, Length=240, Percent_Identity=29.1666666666667, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI32565766, Length=300, Percent_Identity=28, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325166, Length=197, Percent_Identity=24.3654822335025, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24639257, Length=290, Percent_Identity=27.9310344827586, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI281359715, Length=290, Percent_Identity=27.9310344827586, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI281359713, Length=290, Percent_Identity=27.9310344827586, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24639250, Length=290, Percent_Identity=27.9310344827586, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI18543267, Length=290, Percent_Identity=27.9310344827586, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24639252, Length=290, Percent_Identity=27.9310344827586, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24585130, Length=243, Percent_Identity=28.8065843621399, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI21358499, Length=338, Percent_Identity=26.9230769230769, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 59766; Mature: 59766

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVIIGSVAAGTSVAAKARRNNEDAQITIYDRDYDISYSGCGIPYYVGGEVESRDDLTP
CEEEEEECCCCCCHHHHHHHCCCCCCEEEEEECCEECCCCCCCCCEEECCCCCCCCCCCC
RDAAFFKKRYNIDVMTRHNVTAVDKDAKTVTVENLETGDTFTDAYDVLVLATGASSIIPP
CHHHHHHHHCCEEEEEECCCEEECCCCCEEEEECCCCCCCHHCCEEEEEEECCCCCCCCC
IPGVKSDNVFPIRNIQHAEATRSFVDSTDPKHATIIGAGFIGLEMAEQLKLRGVDVTIIE
CCCCCCCCEECCCCCCHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCHHHH
RVPQVMPPLDKDMACRVEEHLEKNGIELMLGETVTELVGDGHVERVVTESGKTIETDFVI
HHHHHCCCCCCHHHHHHHHHHHCCCCEEEECHHHHHHHCCCCHHHHHHCCCCEEEEEEEE
LSVGVRPNVELAMNMGVKLGETGAIAVNERMETNIPDVYAAGDVAESFSIVTGKPIWRPL
EEECCCCCCEEEEECCEEECCCCEEEECCCCCCCCCCEEECCCHHHCCEEEECCCHHHHC
GSTANKMGRTAGDVITGGHLEHRGILGTGIFKVFGLAVAQTGLAEKEARELGYDIEVLHN
CHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEEC
TKPDKPAYMGGKDMTIKAVADRATRQLLGVQIVGFEGVDKRIDVFVTAITLKAKVDDLFH
CCCCCCCCCCCCCCEEEHHHHHHHHHHHCEEEEECCCCCCEEEEEEEEEEEEEECCCEEE
LDLAYAPPFSTTKDPVMYTGMVLANSIDKAARLITPAELQARIDAGEDMQIIDTRKASQF
EEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCHHHHEECCCCCCEEEEECCHHHHH
EKACVDCAVNVPLGNLREAAKDMDKDKPTVVYCNGGVTGNAAQNVLRNLGFTDVYNLSGG
HHHHHHEEEECCCHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEECCCC
NKNYQLFKKYGN
CCCHHHHEECCC
>Mature Secondary Structure
MKLVIIGSVAAGTSVAAKARRNNEDAQITIYDRDYDISYSGCGIPYYVGGEVESRDDLTP
CEEEEEECCCCCCHHHHHHHCCCCCCEEEEEECCEECCCCCCCCCEEECCCCCCCCCCCC
RDAAFFKKRYNIDVMTRHNVTAVDKDAKTVTVENLETGDTFTDAYDVLVLATGASSIIPP
CHHHHHHHHCCEEEEEECCCEEECCCCCEEEEECCCCCCCHHCCEEEEEEECCCCCCCCC
IPGVKSDNVFPIRNIQHAEATRSFVDSTDPKHATIIGAGFIGLEMAEQLKLRGVDVTIIE
CCCCCCCCEECCCCCCHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCHHHH
RVPQVMPPLDKDMACRVEEHLEKNGIELMLGETVTELVGDGHVERVVTESGKTIETDFVI
HHHHHCCCCCCHHHHHHHHHHHCCCCEEEECHHHHHHHCCCCHHHHHHCCCCEEEEEEEE
LSVGVRPNVELAMNMGVKLGETGAIAVNERMETNIPDVYAAGDVAESFSIVTGKPIWRPL
EEECCCCCCEEEEECCEEECCCCEEEECCCCCCCCCCEEECCCHHHCCEEEECCCHHHHC
GSTANKMGRTAGDVITGGHLEHRGILGTGIFKVFGLAVAQTGLAEKEARELGYDIEVLHN
CHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEEC
TKPDKPAYMGGKDMTIKAVADRATRQLLGVQIVGFEGVDKRIDVFVTAITLKAKVDDLFH
CCCCCCCCCCCCCCEEEHHHHHHHHHHHCEEEEECCCCCCEEEEEEEEEEEEEECCCEEE
LDLAYAPPFSTTKDPVMYTGMVLANSIDKAARLITPAELQARIDAGEDMQIIDTRKASQF
EEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCHHHHEECCCCCCEEEEECCHHHHH
EKACVDCAVNVPLGNLREAAKDMDKDKPTVVYCNGGVTGNAAQNVLRNLGFTDVYNLSGG
HHHHHHEEEECCCHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEECCCC
NKNYQLFKKYGN
CCCHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]