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The map label for this gene is ribBA [H]

Identifier: 229916729

GI number: 229916729

Start: 945808

End: 946983

Strand: Reverse

Name: ribBA [H]

Synonym: EAT1b_1002

Alternate gene names: 229916729

Gene position: 946983-945808 (Counterclockwise)

Preceding gene: 229916730

Following gene: 229916728

Centisome position: 31.57

GC content: 55.61

Gene sequence:

>1176_bases
ATGTTTGATTCGATTGAACTGGCGATTGAGGAACTGAGACGAGGGCGTCCCATCATCGTCGTGGATGACGAGGACCGTGA
GAATGAAGGGGACTTTGTCGTACTCGGTGACAAGATGACGCCGGAAACGATGAACTTTTTGATCACGGAAGGGAAAGGGC
TCGTCTGTAGCGCCATCGCAGAAGAAGTGGCAGTTCGTCTCGACCTCGCGCCGATGGTAACGAACAGTACGGACCCACAC
GGTACCGCCTTCACGGTCAGTGTTGACCATATCGATTCGACGACTGGCATCTCGGCGAGTGAACGGTCTCACACCGTTCG
TGAGTTAGCGAACCCATCGTCCCGTCCGTCCGATTTTCAACGTCCGGGACATCTGTTCCCGTTGATTGCGAAAAAGGGAG
GCGTCTCCGTTCGACGAGGTCATACCGAAGCGTCCGTCGACCTGGCGCGACTCGCAGGAAGTGAGCCGGTCGCAGTCATC
TGTGAAATCATTCGAGAAGACGGGGAGATGGCGCGCGTACCGGATTTAGTCCAAGTCGCCGAACGCCACGGGTTGGCATT
CATCACCATCGAAGCGATCGTTCGATATATGGAGACGAACCTCGTCACACGTGTTGCGGACGTGTCTCTACCTTCCTCGA
AAGGAACGTTTCGCATGATGGGGTATGAGAATCGAATGGATCGTGAAGAGCATGTGGCGCTCGTGACGGAAACGCTCGAA
GAAGTCCCGCTCGTTCGCATTCATTCCGAGTGTCTGACCGGTGACGTCTTCGGCTCGTTCCGATGTGACTGCGGACCGCA
ACTCGACGCGGCGATGACACGAATCGAGCAGGAATCGGGCATCGTGCTCTATATGCGTCAAGAAGGGCGAGGCATCGGAC
TGTTGAACAAATTGAAGGCGTACGCCCTTCAAGAGAACGGATTGGACACGGTCGAGGCGAATGTGGCGCTCGGATTGCAT
CCGGACCTTCGGGACTACCGAGTGAGCGCGGCGATGCTGCGTGACCTTGGCGTCACCCATGTCCGGCTCATGACGAACAA
CCCCGAGAAAGTCGATGCCTTGGAATCCTGTGGCATCACGGTCGTCGAACGCGTTCCGATTCATGTCGGTGCGCATGAAG
CGAACGAATCGTATCGGCTGACGAAACAACTCAAAATGAATCATATTGGAGGATAA

Upstream 100 bases:

>100_bases
AATGTGATCTGTTAGCAAAATATATGGAAAAGGTCGTCGGGCAGTCGAAGATGACGCTCGAGTCCTTGACAGAACAAGGA
TATGGAAAGGCGGGATGGTA

Downstream 100 bases:

>100_bases
TGGACATGACCTATACATTTGAAGGAAATTTGGTTGGAGAAGGATTAAAGATTGGAATCGTCGTCGGACGGTTCAACGAC
TTGATTACGATGCGTCTGCT

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: 3,4-dihydroxy-2-butanone 4-phosphate synthase; DHBP synthase; GTP cyclohydrolase-2; GTP cyclohydrolase II [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MFDSIELAIEELRRGRPIIVVDDEDRENEGDFVVLGDKMTPETMNFLITEGKGLVCSAIAEEVAVRLDLAPMVTNSTDPH
GTAFTVSVDHIDSTTGISASERSHTVRELANPSSRPSDFQRPGHLFPLIAKKGGVSVRRGHTEASVDLARLAGSEPVAVI
CEIIREDGEMARVPDLVQVAERHGLAFITIEAIVRYMETNLVTRVADVSLPSSKGTFRMMGYENRMDREEHVALVTETLE
EVPLVRIHSECLTGDVFGSFRCDCGPQLDAAMTRIEQESGIVLYMRQEGRGIGLLNKLKAYALQENGLDTVEANVALGLH
PDLRDYRVSAAMLRDLGVTHVRLMTNNPEKVDALESCGITVVERVPIHVGAHEANESYRLTKQLKMNHIGG

Sequences:

>Translated_391_residues
MFDSIELAIEELRRGRPIIVVDDEDRENEGDFVVLGDKMTPETMNFLITEGKGLVCSAIAEEVAVRLDLAPMVTNSTDPH
GTAFTVSVDHIDSTTGISASERSHTVRELANPSSRPSDFQRPGHLFPLIAKKGGVSVRRGHTEASVDLARLAGSEPVAVI
CEIIREDGEMARVPDLVQVAERHGLAFITIEAIVRYMETNLVTRVADVSLPSSKGTFRMMGYENRMDREEHVALVTETLE
EVPLVRIHSECLTGDVFGSFRCDCGPQLDAAMTRIEQESGIVLYMRQEGRGIGLLNKLKAYALQENGLDTVEANVALGLH
PDLRDYRVSAAMLRDLGVTHVRLMTNNPEKVDALESCGITVVERVPIHVGAHEANESYRLTKQLKMNHIGG
>Mature_391_residues
MFDSIELAIEELRRGRPIIVVDDEDRENEGDFVVLGDKMTPETMNFLITEGKGLVCSAIAEEVAVRLDLAPMVTNSTDPH
GTAFTVSVDHIDSTTGISASERSHTVRELANPSSRPSDFQRPGHLFPLIAKKGGVSVRRGHTEASVDLARLAGSEPVAVI
CEIIREDGEMARVPDLVQVAERHGLAFITIEAIVRYMETNLVTRVADVSLPSSKGTFRMMGYENRMDREEHVALVTETLE
EVPLVRIHSECLTGDVFGSFRCDCGPQLDAAMTRIEQESGIVLYMRQEGRGIGLLNKLKAYALQENGLDTVEANVALGLH
PDLRDYRVSAAMLRDLGVTHVRLMTNNPEKVDALESCGITVVERVPIHVGAHEANESYRLTKQLKMNHIGG

Specific function: Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1787533, Length=191, Percent_Identity=53.9267015706806, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI1789420, Length=196, Percent_Identity=47.4489795918367, Blast_Score=191, Evalue=5e-50,
Organism=Saccharomyces cerevisiae, GI6320695, Length=207, Percent_Identity=43.9613526570048, Blast_Score=173, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6319438, Length=170, Percent_Identity=45.8823529411765, Blast_Score=126, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12; =3.5.4.25 [H]

Molecular weight: Translated: 43008; Mature: 43008

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDSIELAIEELRRGRPIIVVDDEDRENEGDFVVLGDKMTPETMNFLITEGKGLVCSAIA
CCCHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEECCCCCCCCEEEEEECCCCEEHHHHH
EEVAVRLDLAPMVTNSTDPHGTAFTVSVDHIDSTTGISASERSHTVRELANPSSRPSDFQ
HHHHHEEEECHHCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCC
RPGHLFPLIAKKGGVSVRRGHTEASVDLARLAGSEPVAVICEIIREDGEMARVPDLVQVA
CCCCEEEEEECCCCCEEECCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHH
ERHGLAFITIEAIVRYMETNLVTRVADVSLPSSKGTFRMMGYENRMDREEHVALVTETLE
HHCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHH
EVPLVRIHSECLTGDVFGSFRCDCGPQLDAAMTRIEQESGIVLYMRQEGRGIGLLNKLKA
HCCEEEEHHHHHCCCCCCCEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHH
YALQENGLDTVEANVALGLHPDLRDYRVSAAMLRDLGVTHVRLMTNNPEKVDALESCGIT
HHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHCCCE
VVERVPIHVGAHEANESYRLTKQLKMNHIGG
EEEECCEEECCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MFDSIELAIEELRRGRPIIVVDDEDRENEGDFVVLGDKMTPETMNFLITEGKGLVCSAIA
CCCHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEECCCCCCCCEEEEEECCCCEEHHHHH
EEVAVRLDLAPMVTNSTDPHGTAFTVSVDHIDSTTGISASERSHTVRELANPSSRPSDFQ
HHHHHEEEECHHCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCC
RPGHLFPLIAKKGGVSVRRGHTEASVDLARLAGSEPVAVICEIIREDGEMARVPDLVQVA
CCCCEEEEEECCCCCEEECCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHH
ERHGLAFITIEAIVRYMETNLVTRVADVSLPSSKGTFRMMGYENRMDREEHVALVTETLE
HHCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHH
EVPLVRIHSECLTGDVFGSFRCDCGPQLDAAMTRIEQESGIVLYMRQEGRGIGLLNKLKA
HCCEEEEHHHHHCCCCCCCEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHH
YALQENGLDTVEANVALGLHPDLRDYRVSAAMLRDLGVTHVRLMTNNPEKVDALESCGIT
HHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHCCCE
VVERVPIHVGAHEANESYRLTKQLKMNHIGG
EEEECCEEECCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA