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The map label for this gene is ribH [H]

Identifier: 229916728

GI number: 229916728

Start: 945338

End: 945802

Strand: Reverse

Name: ribH [H]

Synonym: EAT1b_1001

Alternate gene names: 229916728

Gene position: 945802-945338 (Counterclockwise)

Preceding gene: 229916729

Following gene: 229916727

Centisome position: 31.53

GC content: 52.04

Gene sequence:

>465_bases
ATGACCTATACATTTGAAGGAAATTTGGTTGGAGAAGGATTAAAGATTGGAATCGTCGTCGGACGGTTCAACGACTTGAT
TACGATGCGTCTGCTTGACGGGGCGAAGGATGCCTTGAGACGTCATGGGGTGAAAGAAGAGGATGTATCGCTTGCGTTCG
TCCCGGGTGCATTTGAACTCCCCCTCGTCGCGAAAAAAATGGCGATGAGCAAAAAATACGACGCGGTCATCACGCTCGGA
GCCGTCATCCGTGGTGCGACCCCGCATTTTGATTACGTCTGTAACGAAGCGGCAAAAGGGATCGCCCAGGCGAGCTATCA
ATCCGAAGTCCCGGTCATCTTTGGTGTGTTGACGACGGAGACGATTGAGCAGGCGATTGAGCGTGCGGGAACAAAAGCAG
GTAACAAAGGGTGGGAAGCGGCGACTTCCGCCATCGAGATGGCCAATCTGTTAAAGCAAGTCTAA

Upstream 100 bases:

>100_bases
TCGTCGAACGCGTTCCGATTCATGTCGGTGCGCATGAAGCGAACGAATCGTATCGGCTGACGAAACAACTCAAAATGAAT
CATATTGGAGGATAATGGAC

Downstream 100 bases:

>100_bases
TCAAAACCGGGTGGCGACCACCCGGTTTTTCAAATGGATAAACTAGGATAAAAAAACTGAAAATTGGGTAAAATAAGTGC
ATGGAATGAATGCATGTATT

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MTYTFEGNLVGEGLKIGIVVGRFNDLITMRLLDGAKDALRRHGVKEEDVSLAFVPGAFELPLVAKKMAMSKKYDAVITLG
AVIRGATPHFDYVCNEAAKGIAQASYQSEVPVIFGVLTTETIEQAIERAGTKAGNKGWEAATSAIEMANLLKQV

Sequences:

>Translated_154_residues
MTYTFEGNLVGEGLKIGIVVGRFNDLITMRLLDGAKDALRRHGVKEEDVSLAFVPGAFELPLVAKKMAMSKKYDAVITLG
AVIRGATPHFDYVCNEAAKGIAQASYQSEVPVIFGVLTTETIEQAIERAGTKAGNKGWEAATSAIEMANLLKQV
>Mature_153_residues
TYTFEGNLVGEGLKIGIVVGRFNDLITMRLLDGAKDALRRHGVKEEDVSLAFVPGAFELPLVAKKMAMSKKYDAVITLGA
VIRGATPHFDYVCNEAAKGIAQASYQSEVPVIFGVLTTETIEQAIERAGTKAGNKGWEAATSAIEMANLLKQV

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=151, Percent_Identity=56.2913907284768, Blast_Score=171, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6324429, Length=147, Percent_Identity=34.0136054421769, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 16546; Mature: 16415

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYTFEGNLVGEGLKIGIVVGRFNDLITMRLLDGAKDALRRHGVKEEDVSLAFVPGAFEL
CEEEECCCEECCCEEEEEEEECCCHHHHHHHHHCHHHHHHHCCCCCCCCEEEEECCCCCC
PLVAKKMAMSKKYDAVITLGAVIRGATPHFDYVCNEAAKGIAQASYQSEVPVIFGVLTTE
HHHHHHHHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHH
TIEQAIERAGTKAGNKGWEAATSAIEMANLLKQV
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TYTFEGNLVGEGLKIGIVVGRFNDLITMRLLDGAKDALRRHGVKEEDVSLAFVPGAFEL
EEEECCCEECCCEEEEEEEECCCHHHHHHHHHCHHHHHHHCCCCCCCCEEEEECCCCCC
PLVAKKMAMSKKYDAVITLGAVIRGATPHFDYVCNEAAKGIAQASYQSEVPVIFGVLTTE
HHHHHHHHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHH
TIEQAIERAGTKAGNKGWEAATSAIEMANLLKQV
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA