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The map label for this gene is degS [H]

Identifier: 229916671

GI number: 229916671

Start: 891663

End: 892787

Strand: Reverse

Name: degS [H]

Synonym: EAT1b_0943

Alternate gene names: 229916671

Gene position: 892787-891663 (Counterclockwise)

Preceding gene: 229916674

Following gene: 229916670

Centisome position: 29.76

GC content: 48.09

Gene sequence:

>1125_bases
GTGAATCATATTACCGATCGGACAGCTTTAGAACATATCATAACAAATATGATTGAAACGGTGACGGAAAGTAAAGAGGA
GATTGTCCGTATAACCGAAAGTTCTGCAACTGAATATTCAGCAATTCAAAACGAGTTAAAAGAATTGACGGATAAAATCG
AGTTCTACATCGAGGAGTCCGATCGACTCGACCGACTCGTGAAAGCTGCAAAGGCCAAGCTCGTTCAAGTCAGCAAAAAG
TTTCATATACATAGTGAACAAGAAATTCGTGAAGCCTACGAACGGGCGAATCAAATGCAACTCGAGCGTTTTCTTGTTCA
AAAAGAAGAAATGGCGGCACAGCAACGCCGGAATGACTTAGAGCGTCGTCTGCTCATCTTAGAGGATACGATCGAACGTG
CCGAAAAGTTGATCGGTCGTGTGAGTGTCGTCTTGAACTTCTTACGGGATGACCTACAGCAAGAGTATTCGGACATGATG
AAGAAGCAAGAAATGGCCATCGGCGTATTCGAAGCGGCCGAGCGCGAACGGCGTCACCTCGCCCGCGAGATGCACGACGG
TCCAGCGCAATCGCTTGCCCACATCTTGATTCGTGCCGATTTGATTGAAAAGACGTTTGACAAACGAGGAAAAGATGAAG
CATTTGCCGAATTACATGAATTGAAAAAGTTGATTCGTGGGGCACTCGTCGACGTCCGTCGTTTGATCTATGATTTACGT
CCGATGTCGCTTGACGATTTAGGCTTTTTGCCGACGCTCGAGCGCTATCTCCATCAAACGGAGGAGTATACGGCGATCAA
GACACGTCTCAACTATCGGGGGTCGCGTGCGCGATTACCGGAGAAACTGGAGATCAACGTATTCCGTCTCGTTCAAGAAT
CGGTCCAAAATGCGATCAAACATGCAAAAACAGCCGAAATCATCGTCAATGTCGAGCAGGCGAGTGATGTGATTCATATT
CACGTCCGCGACTACGGTGTGGGGTTTGAACCGAGCGCGATTGGCGAAGAGTCGTTCGGGATTGTCGGAATGCGCGAACG
AATTGAATTGGTGAACGGAAGCATCACCATCGACTCGGAAGTCGGCAAAGGGACGGTCGTCCGAATGTCGATTCCGATTC
CGTGA

Upstream 100 bases:

>100_bases
ATTATAGAAAATCTCTCATGTCCGCTGTAAACCTGTTTAGAGTGGGACGATATATAAGAATAGATGAGGATTAACTACCG
AACTATTAGGGGATGGCATC

Downstream 100 bases:

>100_bases
GAGAACAAGGGGGAAGACATACATGGAAATGACACAGACACGCATTGCAATCGTGGATGATCACGAACTGTTCCGTGAAG
GATTGAAGCGGATTTTTGAT

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MNHITDRTALEHIITNMIETVTESKEEIVRITESSATEYSAIQNELKELTDKIEFYIEESDRLDRLVKAAKAKLVQVSKK
FHIHSEQEIREAYERANQMQLERFLVQKEEMAAQQRRNDLERRLLILEDTIERAEKLIGRVSVVLNFLRDDLQQEYSDMM
KKQEMAIGVFEAAERERRHLAREMHDGPAQSLAHILIRADLIEKTFDKRGKDEAFAELHELKKLIRGALVDVRRLIYDLR
PMSLDDLGFLPTLERYLHQTEEYTAIKTRLNYRGSRARLPEKLEINVFRLVQESVQNAIKHAKTAEIIVNVEQASDVIHI
HVRDYGVGFEPSAIGEESFGIVGMRERIELVNGSITIDSEVGKGTVVRMSIPIP

Sequences:

>Translated_374_residues
MNHITDRTALEHIITNMIETVTESKEEIVRITESSATEYSAIQNELKELTDKIEFYIEESDRLDRLVKAAKAKLVQVSKK
FHIHSEQEIREAYERANQMQLERFLVQKEEMAAQQRRNDLERRLLILEDTIERAEKLIGRVSVVLNFLRDDLQQEYSDMM
KKQEMAIGVFEAAERERRHLAREMHDGPAQSLAHILIRADLIEKTFDKRGKDEAFAELHELKKLIRGALVDVRRLIYDLR
PMSLDDLGFLPTLERYLHQTEEYTAIKTRLNYRGSRARLPEKLEINVFRLVQESVQNAIKHAKTAEIIVNVEQASDVIHI
HVRDYGVGFEPSAIGEESFGIVGMRERIELVNGSITIDSEVGKGTVVRMSIPIP
>Mature_374_residues
MNHITDRTALEHIITNMIETVTESKEEIVRITESSATEYSAIQNELKELTDKIEFYIEESDRLDRLVKAAKAKLVQVSKK
FHIHSEQEIREAYERANQMQLERFLVQKEEMAAQQRRNDLERRLLILEDTIERAEKLIGRVSVVLNFLRDDLQQEYSDMM
KKQEMAIGVFEAAERERRHLAREMHDGPAQSLAHILIRADLIEKTFDKRGKDEAFAELHELKKLIRGALVDVRRLIYDLR
PMSLDDLGFLPTLERYLHQTEEYTAIKTRLNYRGSRARLPEKLEINVFRLVQESVQNAIKHAKTAEIIVNVEQASDVIHI
HVRDYGVGFEPSAIGEESFGIVGMRERIELVNGSITIDSEVGKGTVVRMSIPIP

Specific function: Involved in a sensory transduction pathway that affect the production of enzymes that degrade polymeric carbon and nitrogen sources. DegS probably acts as a kinase that phosphorylates degU [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788812, Length=199, Percent_Identity=29.1457286432161, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787474, Length=201, Percent_Identity=27.363184079602, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI87082311, Length=226, Percent_Identity=29.646017699115, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR008595
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR016381 [H]

Pfam domain/function: PF05384 DegS; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 43299; Mature: 43299

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHITDRTALEHIITNMIETVTESKEEIVRITESSATEYSAIQNELKELTDKIEFYIEES
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCH
DRLDRLVKAAKAKLVQVSKKFHIHSEQEIREAYERANQMQLERFLVQKEEMAAQQRRNDL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERRLLILEDTIERAEKLIGRVSVVLNFLRDDLQQEYSDMMKKQEMAIGVFEAAERERRHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AREMHDGPAQSLAHILIRADLIEKTFDKRGKDEAFAELHELKKLIRGALVDVRRLIYDLR
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PMSLDDLGFLPTLERYLHQTEEYTAIKTRLNYRGSRARLPEKLEINVFRLVQESVQNAIK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
HAKTAEIIVNVEQASDVIHIHVRDYGVGFEPSAIGEESFGIVGMRERIELVNGSITIDSE
HCCHHHHEEEEHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEECC
VGKGTVVRMSIPIP
CCCCEEEEEECCCC
>Mature Secondary Structure
MNHITDRTALEHIITNMIETVTESKEEIVRITESSATEYSAIQNELKELTDKIEFYIEES
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCH
DRLDRLVKAAKAKLVQVSKKFHIHSEQEIREAYERANQMQLERFLVQKEEMAAQQRRNDL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERRLLILEDTIERAEKLIGRVSVVLNFLRDDLQQEYSDMMKKQEMAIGVFEAAERERRHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AREMHDGPAQSLAHILIRADLIEKTFDKRGKDEAFAELHELKKLIRGALVDVRRLIYDLR
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PMSLDDLGFLPTLERYLHQTEEYTAIKTRLNYRGSRARLPEKLEINVFRLVQESVQNAIK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
HAKTAEIIVNVEQASDVIHIHVRDYGVGFEPSAIGEESFGIVGMRERIELVNGSITIDSE
HCCHHHHEEEEHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEECC
VGKGTVVRMSIPIP
CCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]