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The map label for this gene is degU [H]

Identifier: 229916670

GI number: 229916670

Start: 890948

End: 891640

Strand: Reverse

Name: degU [H]

Synonym: EAT1b_0942

Alternate gene names: 229916670

Gene position: 891640-890948 (Counterclockwise)

Preceding gene: 229916671

Following gene: 229916669

Centisome position: 29.72

GC content: 50.79

Gene sequence:

>693_bases
ATGGAAATGACACAGACACGCATTGCAATCGTGGATGATCACGAACTGTTCCGTGAAGGATTGAAGCGGATTTTTGATTT
GGAAGATGAATTTACAGTTGTCGCCGAAGGGCGCACGGGTCGTGAAGCCATTCGCATTGCTGGCGAGCAAAAACCAGAAA
TTTTAATCATGGATATCAACATGCCTGACATGAACGGGATCGAGGCGACAAAGCAACTTTCCCTCCTTTCACCGGAAACA
CGTGTCCTCATCCTTTCAATCCATGATGATGAGTCATATATCACGCATGCGCTTGAAGCAGGGGCATCAGGCTTCTTATT
GAAAGAAGTCGCATCGACAGAATTGATCTCGGCAGTCCGTGCCGTCGCAAAAGATGGGGCGTACCTTCATCCGAAAGTGA
CGACGAACGTACTGAAGGAGTACCGTCGCCTCTTGCAATTCAAAGGGGAACAAGCGGGACGCGGCGTCGAGAGCCGTACA
GATGACCCGGTCTATCAATTGTTGTCACGCCGTGAAGTCGAGGTGTTACACCTTCTCGCAGACGGTCGCTCGAACCGAGA
CATCAGTGACATGCTGTTTATCAGTGAGAAGACGGTCAAAAACCACGTCTCCTCCGTGCTTCGTAAAATGGACGTGAACG
ACCGGACACAAGCCGTCGTGGATGCGATTCGCCGGGGTTGGGTCGAGATTTGA

Upstream 100 bases:

>100_bases
TTGGTGAACGGAAGCATCACCATCGACTCGGAAGTCGGCAAAGGGACGGTCGTCCGAATGTCGATTCCGATTCCGTGAGA
GAACAAGGGGGAAGACATAC

Downstream 100 bases:

>100_bases
GCGTCACCGATGCTTTACCTCGTTTTTGTGTTACAATATGGAATGGAATCCTAACATAATTGGAAAAATGAAACGACGTA
AAGTGAGGATATAGTATGGG

Product: two component transcriptional regulator, LuxR family

Products: NA

Alternate protein names: Protease production enhancer protein [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MEMTQTRIAIVDDHELFREGLKRIFDLEDEFTVVAEGRTGREAIRIAGEQKPEILIMDINMPDMNGIEATKQLSLLSPET
RVLILSIHDDESYITHALEAGASGFLLKEVASTELISAVRAVAKDGAYLHPKVTTNVLKEYRRLLQFKGEQAGRGVESRT
DDPVYQLLSRREVEVLHLLADGRSNRDISDMLFISEKTVKNHVSSVLRKMDVNDRTQAVVDAIRRGWVEI

Sequences:

>Translated_230_residues
MEMTQTRIAIVDDHELFREGLKRIFDLEDEFTVVAEGRTGREAIRIAGEQKPEILIMDINMPDMNGIEATKQLSLLSPET
RVLILSIHDDESYITHALEAGASGFLLKEVASTELISAVRAVAKDGAYLHPKVTTNVLKEYRRLLQFKGEQAGRGVESRT
DDPVYQLLSRREVEVLHLLADGRSNRDISDMLFISEKTVKNHVSSVLRKMDVNDRTQAVVDAIRRGWVEI
>Mature_230_residues
MEMTQTRIAIVDDHELFREGLKRIFDLEDEFTVVAEGRTGREAIRIAGEQKPEILIMDINMPDMNGIEATKQLSLLSPET
RVLILSIHDDESYITHALEAGASGFLLKEVASTELISAVRAVAKDGAYLHPKVTTNVLKEYRRLLQFKGEQAGRGVESRT
DDPVYQLLSRREVEVLHLLADGRSNRDISDMLFISEKTVKNHVSSVLRKMDVNDRTQAVVDAIRRGWVEI

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=219, Percent_Identity=34.2465753424658, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1790102, Length=223, Percent_Identity=34.0807174887892, Blast_Score=113, Evalue=8e-27,
Organism=Escherichia coli, GI1788222, Length=219, Percent_Identity=27.3972602739726, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1787473, Length=221, Percent_Identity=33.4841628959276, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1788712, Length=203, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1786747, Length=208, Percent_Identity=27.4038461538462, Blast_Score=85, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 25985; Mature: 25985

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMTQTRIAIVDDHELFREGLKRIFDLEDEFTVVAEGRTGREAIRIAGEQKPEILIMDIN
CCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHCCCCCCCEEEEECC
MPDMNGIEATKQLSLLSPETRVLILSIHDDESYITHALEAGASGFLLKEVASTELISAVR
CCCCCCHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AVAKDGAYLHPKVTTNVLKEYRRLLQFKGEQAGRGVESRTDDPVYQLLSRREVEVLHLLA
HHHHCCCEECCHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCHHHHHHCCCHHHHHHHHH
DGRSNRDISDMLFISEKTVKNHVSSVLRKMDVNDRTQAVVDAIRRGWVEI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEMTQTRIAIVDDHELFREGLKRIFDLEDEFTVVAEGRTGREAIRIAGEQKPEILIMDIN
CCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHCCCCCCCEEEEECC
MPDMNGIEATKQLSLLSPETRVLILSIHDDESYITHALEAGASGFLLKEVASTELISAVR
CCCCCCHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AVAKDGAYLHPKVTTNVLKEYRRLLQFKGEQAGRGVESRTDDPVYQLLSRREVEVLHLLA
HHHHCCCEECCHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCHHHHHHCCCHHHHHHHHH
DGRSNRDISDMLFISEKTVKNHVSSVLRKMDVNDRTQAVVDAIRRGWVEI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3136143; 3141378; 3141377; 9384377 [H]