Definition Exiguobacterium sp. AT1b, complete genome.
Accession NC_012673
Length 2,999,895

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The map label for this gene is rnr [H]

Identifier: 229916580

GI number: 229916580

Start: 803779

End: 806184

Strand: Reverse

Name: rnr [H]

Synonym: EAT1b_0852

Alternate gene names: 229916580

Gene position: 806184-803779 (Counterclockwise)

Preceding gene: 229916581

Following gene: 229916579

Centisome position: 26.87

GC content: 56.4

Gene sequence:

>2406_bases
TTGAATTTACGTGACCAATTACTAGAGATCTTGCAGGCGAGCGAAAAACCGCTCTCTGTGGATCAACTGACCGAGCGACT
ACAGCTCGCGTCGACGGATGACTTCAAAGAGCTCATCCGCACATTGAATGCCCTCGAGGAAGAGGGTGCCATCGGCCGGA
CGCGGACGAACCGTTACGGGACGCTCGCCACGCTCGGACAAGTCGCGGGAATCATCTCGATTCACCAGCGCGGCTTCGGC
TTCTTGTCGGTCGAAGGGGAAGCGGAAGACGTGTTCTTGCCGCCCGACCAACTGAAGGACGTCTACCATGGCGATACGAT
CCTCGTTAAAAAACGCGAGGACAATCGTGGCAAGACGGAAGGGATTTTATTGAAAGTACTGAAGCGCGGACTCTCCGAGT
TCGTCGGGACGTATACGCTCCCGAGCGGTCGACTCGACCAGTTCGCCTTCATCGAGCCGGATGATAAACGCATCAACTTC
TGGCCGGTCGTCAACCCGGACAAGTCACTCGGTGCCGTCGACGGACATAAAGTCGTCGTGCGCATCACGAAGTATCCGGA
CGGACGCTTCGCCGGTGCCTGTGACGTCGTCCGTATCATCGGGCATAAGAACGACCCTGGCGTCGACATCTTGTCGATCG
TCTATAAGCACGGCATCCCGACGGAGTTCCCGGAGGACGTGATCGCCCAGGCGAACGCGGTACCGGACGAGGCCGACGAG
AAAGACTTCATCGGACGCGTCGACCTTCGTGACGAGACGATCTTCACGATTGACGGTGAAGATGCGAAAGACTTGGACGA
TGCCGTCCACGTCAAAAAACTTGATAACGGCAACTACGAGCTCGGTGTCCATATCGCTGACGTCTCGCATTACGTGAAAG
AGGGCTCACCACTAGACGTCGAGGCGTTCGAACGTGGGACGAGTGTGTATCTCGTCGACCGTGTCATTCCGATGCTGCCG
CACCGACTCTCGAACGGGATTTGTTCCCTCAACCCGCACGTCAACCGCTTGACGCTCAGCTGCGTCATGGAGATCTCCCC
GCAAAACGGGAAGGTCGTTCGCCATGATCTGTTCCCGAGTGTCATCAAGACGACGGAGCGGATGACGTATACGAACGTCC
GTGAGATCATCGAACGTGATGACGAAGAGACATTGAAAAAGTACGAACCGTTCATCGGTGAGTTCGACCTCATGGCCGAG
CTCGCGGAAGTCCTTCGGAAACGTCGTAACTCGCGCGGTGCCATCAACTTCGATTTCGCTGAGGCGAAGGTTGTCGTCAA
CGAGGAAGGGAAGCCGGCAGATATCGTGCTTCGTCCACGTTCGGTCGCCGAGAAGTTGATCGAAGAGTTCATGCTCGCGG
CCAACGAGACGGTCGCGGAACACTTCCACAAGATGGACGTGCCGTTCATCTATCGTGTCCACGACAATCCGAAACCGGAC
AAGCTCGACTTCTTCTTCGACTTTGTCGCAAACTTTGGCGTTCACATCGAACGCATCAAAGGGCAGACGGTCGAACCGAA
GACGCTTCAAAAGATTTTGAAGGCGATCGACGGAGAACCGGAAGAGCCGGTCATCAGCACGATTATGCTTCGTTCGATGC
AACAGGCGAAATATGACGACGTCTCGCTCGGTCACTTCGGACTCGCGACAGACTTCTATACGCACTTCACGTCACCGATT
CGTCGTTATCCGGACTTGATCGTCCACCGTCTCATGCGCACGTACGTCTTCAACAACGATTTGTCGGAGAAGACGATCGC
GAAGTACGAGGACCGTCTCGGGGCGATCGCCGAACAGGCATCGAAACGGGAACGTCGCTCGGTCGACGCAGAGCGCGAGA
CGCAGGCGCTCAAGAAAGCCGAATACATGGAAGCCCATCTCGGTGAAGAGTTCGATGGTGTCGTCGCCGGCGTCACGAAC
TTCGGGATGTTCATCGAACTTCCGAATACGATTGAAGGGCTTGTCCGTCTCCAGTCGATGGATGACTACTACCACTTTGA
CGAATCACAGCTCATGCTCCTCGGGGAGCGGACGAAACGTCAATTCCGCATCGGGGACGCCGTCCGTGTCAAAGTCGATG
CCGTCAACTTAGACGAGCGGACGATCGACTTCACGGTCGTCGGCATGCCGAAACGGGAACAGTCAAGCCGTCGCCAACCG
ACGACGATCAAAGCGAAAGGCGGTCGTCCGAAGAAGGACGAGAAAGACCGTCGTGGCGGTCGCGGTCGGGACGACAAGAA
GAAGCGCGGCAAACCAGGAAGACCTGGCAAGCCGGGCAAACCAGGTGAGAAACCGAAACGAGACGGGGAGAAGTCTTCCC
AAGGCCGTTCGGCACTCGACCTGAAGAAGAAAGACAAGCACAAACGAAAAGGCGACGCCAAACGAGGTGCGAAGAAACGT
CGCTGA

Upstream 100 bases:

>100_bases
ACACGTGATCACACTCGACAAAGAAAAAGAGAAACTGCACCAGGACGTGCTCGATTTTCTCGAAACGTTAGACTGGTCAG
TCTAAGAAGGAGGTGTCACG

Downstream 100 bases:

>100_bases
CGGGGAAGGGCTCATCCCTTCCTCCGTATCTTGTAGATAAAGGACTGAATGTGTATGGCCAAGAAGAAAGATTCGAACGC
ACTCGCCCAAAACCGCAAGG

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 801; Mature: 801

Protein sequence:

>801_residues
MNLRDQLLEILQASEKPLSVDQLTERLQLASTDDFKELIRTLNALEEEGAIGRTRTNRYGTLATLGQVAGIISIHQRGFG
FLSVEGEAEDVFLPPDQLKDVYHGDTILVKKREDNRGKTEGILLKVLKRGLSEFVGTYTLPSGRLDQFAFIEPDDKRINF
WPVVNPDKSLGAVDGHKVVVRITKYPDGRFAGACDVVRIIGHKNDPGVDILSIVYKHGIPTEFPEDVIAQANAVPDEADE
KDFIGRVDLRDETIFTIDGEDAKDLDDAVHVKKLDNGNYELGVHIADVSHYVKEGSPLDVEAFERGTSVYLVDRVIPMLP
HRLSNGICSLNPHVNRLTLSCVMEISPQNGKVVRHDLFPSVIKTTERMTYTNVREIIERDDEETLKKYEPFIGEFDLMAE
LAEVLRKRRNSRGAINFDFAEAKVVVNEEGKPADIVLRPRSVAEKLIEEFMLAANETVAEHFHKMDVPFIYRVHDNPKPD
KLDFFFDFVANFGVHIERIKGQTVEPKTLQKILKAIDGEPEEPVISTIMLRSMQQAKYDDVSLGHFGLATDFYTHFTSPI
RRYPDLIVHRLMRTYVFNNDLSEKTIAKYEDRLGAIAEQASKRERRSVDAERETQALKKAEYMEAHLGEEFDGVVAGVTN
FGMFIELPNTIEGLVRLQSMDDYYHFDESQLMLLGERTKRQFRIGDAVRVKVDAVNLDERTIDFTVVGMPKREQSSRRQP
TTIKAKGGRPKKDEKDRRGGRGRDDKKKRGKPGRPGKPGKPGEKPKRDGEKSSQGRSALDLKKKDKHKRKGDAKRGAKKR
R

Sequences:

>Translated_801_residues
MNLRDQLLEILQASEKPLSVDQLTERLQLASTDDFKELIRTLNALEEEGAIGRTRTNRYGTLATLGQVAGIISIHQRGFG
FLSVEGEAEDVFLPPDQLKDVYHGDTILVKKREDNRGKTEGILLKVLKRGLSEFVGTYTLPSGRLDQFAFIEPDDKRINF
WPVVNPDKSLGAVDGHKVVVRITKYPDGRFAGACDVVRIIGHKNDPGVDILSIVYKHGIPTEFPEDVIAQANAVPDEADE
KDFIGRVDLRDETIFTIDGEDAKDLDDAVHVKKLDNGNYELGVHIADVSHYVKEGSPLDVEAFERGTSVYLVDRVIPMLP
HRLSNGICSLNPHVNRLTLSCVMEISPQNGKVVRHDLFPSVIKTTERMTYTNVREIIERDDEETLKKYEPFIGEFDLMAE
LAEVLRKRRNSRGAINFDFAEAKVVVNEEGKPADIVLRPRSVAEKLIEEFMLAANETVAEHFHKMDVPFIYRVHDNPKPD
KLDFFFDFVANFGVHIERIKGQTVEPKTLQKILKAIDGEPEEPVISTIMLRSMQQAKYDDVSLGHFGLATDFYTHFTSPI
RRYPDLIVHRLMRTYVFNNDLSEKTIAKYEDRLGAIAEQASKRERRSVDAERETQALKKAEYMEAHLGEEFDGVVAGVTN
FGMFIELPNTIEGLVRLQSMDDYYHFDESQLMLLGERTKRQFRIGDAVRVKVDAVNLDERTIDFTVVGMPKREQSSRRQP
TTIKAKGGRPKKDEKDRRGGRGRDDKKKRGKPGRPGKPGKPGEKPKRDGEKSSQGRSALDLKKKDKHKRKGDAKRGAKKR
R
>Mature_801_residues
MNLRDQLLEILQASEKPLSVDQLTERLQLASTDDFKELIRTLNALEEEGAIGRTRTNRYGTLATLGQVAGIISIHQRGFG
FLSVEGEAEDVFLPPDQLKDVYHGDTILVKKREDNRGKTEGILLKVLKRGLSEFVGTYTLPSGRLDQFAFIEPDDKRINF
WPVVNPDKSLGAVDGHKVVVRITKYPDGRFAGACDVVRIIGHKNDPGVDILSIVYKHGIPTEFPEDVIAQANAVPDEADE
KDFIGRVDLRDETIFTIDGEDAKDLDDAVHVKKLDNGNYELGVHIADVSHYVKEGSPLDVEAFERGTSVYLVDRVIPMLP
HRLSNGICSLNPHVNRLTLSCVMEISPQNGKVVRHDLFPSVIKTTERMTYTNVREIIERDDEETLKKYEPFIGEFDLMAE
LAEVLRKRRNSRGAINFDFAEAKVVVNEEGKPADIVLRPRSVAEKLIEEFMLAANETVAEHFHKMDVPFIYRVHDNPKPD
KLDFFFDFVANFGVHIERIKGQTVEPKTLQKILKAIDGEPEEPVISTIMLRSMQQAKYDDVSLGHFGLATDFYTHFTSPI
RRYPDLIVHRLMRTYVFNNDLSEKTIAKYEDRLGAIAEQASKRERRSVDAERETQALKKAEYMEAHLGEEFDGVVAGVTN
FGMFIELPNTIEGLVRLQSMDDYYHFDESQLMLLGERTKRQFRIGDAVRVKVDAVNLDERTIDFTVVGMPKREQSSRRQP
TTIKAKGGRPKKDEKDRRGGRGRDDKKKRGKPGRPGKPGKPGEKPKRDGEKSSQGRSALDLKKKDKHKRKGDAKRGAKKR
R

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=618, Percent_Identity=27.9935275080906, Blast_Score=226, Evalue=7e-59,
Organism=Homo sapiens, GI190014623, Length=618, Percent_Identity=28.3171521035599, Blast_Score=225, Evalue=1e-58,
Organism=Homo sapiens, GI134288890, Length=450, Percent_Identity=31.7777777777778, Blast_Score=199, Evalue=9e-51,
Organism=Homo sapiens, GI19115966, Length=714, Percent_Identity=24.6498599439776, Blast_Score=175, Evalue=2e-43,
Organism=Homo sapiens, GI219521928, Length=714, Percent_Identity=24.9299719887955, Blast_Score=174, Evalue=3e-43,
Organism=Homo sapiens, GI156105695, Length=177, Percent_Identity=32.2033898305085, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI156105693, Length=181, Percent_Identity=31.4917127071823, Blast_Score=77, Evalue=5e-14,
Organism=Escherichia coli, GI87082383, Length=729, Percent_Identity=37.5857338820302, Blast_Score=474, Evalue=1e-135,
Organism=Escherichia coli, GI1787542, Length=646, Percent_Identity=26.1609907120743, Blast_Score=170, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17553506, Length=501, Percent_Identity=31.5369261477046, Blast_Score=202, Evalue=8e-52,
Organism=Caenorhabditis elegans, GI212645896, Length=503, Percent_Identity=30.4174950298211, Blast_Score=201, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6324552, Length=487, Percent_Identity=31.8275154004107, Blast_Score=201, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6320499, Length=461, Percent_Identity=23.644251626898, Blast_Score=98, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6323943, Length=433, Percent_Identity=24.4803695150115, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24649634, Length=551, Percent_Identity=31.5789473684211, Blast_Score=221, Evalue=2e-57,
Organism=Drosophila melanogaster, GI24654592, Length=572, Percent_Identity=27.972027972028, Blast_Score=176, Evalue=5e-44,
Organism=Drosophila melanogaster, GI19922976, Length=572, Percent_Identity=27.972027972028, Blast_Score=176, Evalue=6e-44,
Organism=Drosophila melanogaster, GI24654597, Length=572, Percent_Identity=27.972027972028, Blast_Score=176, Evalue=6e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805 [H]

Pfam domain/function: PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 90767; Mature: 90767

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MNLRDQLLEILQASEKPLSVDQLTERLQLASTDDFKELIRTLNALEEEGAIGRTRTNRYG
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
TLATLGQVAGIISIHQRGFGFLSVEGEAEDVFLPPDQLKDVYHGDTILVKKREDNRGKTE
HHHHHHHHHHHHHHHCCCCEEEEECCCCCCEECCHHHHHHHHCCCEEEEEECCCCCCCHH
GILLKVLKRGLSEFVGTYTLPSGRLDQFAFIEPDDKRINFWPVVNPDKSLGAVDGHKVVV
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCEEEEEECCCCCCCCCCCCCCEEEE
RITKYPDGRFAGACDVVRIIGHKNDPGVDILSIVYKHGIPTEFPEDVIAQANAVPDEADE
EEEECCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCC
KDFIGRVDLRDETIFTIDGEDAKDLDDAVHVKKLDNGNYELGVHIADVSHYVKEGSPLDV
CCCCEEEECCCCEEEEECCCCCHHHHHHHHHEEECCCCEEEEEEEEHHHHHHHCCCCCCH
EAFERGTSVYLVDRVIPMLPHRLSNGICSLNPHVNRLTLSCVMEISPQNGKVVRHDLFPS
HHHHCCCEEEEHHHHHHHHHHHHHCCEEECCCCCHHEEEEEEEEECCCCCCEEEHHHHHH
VIKTTERMTYTNVREIIERDDEETLKKYEPFIGEFDLMAELAEVLRKRRNSRGAINFDFA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEE
EAKVVVNEEGKPADIVLRPRSVAEKLIEEFMLAANETVAEHFHKMDVPFIYRVHDNPKPD
EEEEEECCCCCCCEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCC
KLDFFFDFVANFGVHIERIKGQTVEPKTLQKILKAIDGEPEEPVISTIMLRSMQQAKYDD
HHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
VSLGHFGLATDFYTHFTSPIRRYPDLIVHRLMRTYVFNNDLSEKTIAKYEDRLGAIAEQA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
SKRERRSVDAERETQALKKAEYMEAHLGEEFDGVVAGVTNFGMFIELPNTIEGLVRLQSM
HHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEECCHHHHHHHHHHHC
DDYYHFDESQLMLLGERTKRQFRIGDAVRVKVDAVNLDERTIDFTVVGMPKREQSSRRQP
CHHHCCCCCCEEEEEHHHHHHEECCCEEEEEEEEECCCCCEEEEEEECCCCHHHHHCCCC
TTIKAKGGRPKKDEKDRRGGRGRDDKKKRGKPGRPGKPGKPGEKPKRDGEKSSQGRSALD
CEEEECCCCCCCCHHHHCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHC
LKKKDKHKRKGDAKRGAKKRR
CHHHHHHHHCCCHHCCCCCCC
>Mature Secondary Structure
MNLRDQLLEILQASEKPLSVDQLTERLQLASTDDFKELIRTLNALEEEGAIGRTRTNRYG
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
TLATLGQVAGIISIHQRGFGFLSVEGEAEDVFLPPDQLKDVYHGDTILVKKREDNRGKTE
HHHHHHHHHHHHHHHCCCCEEEEECCCCCCEECCHHHHHHHHCCCEEEEEECCCCCCCHH
GILLKVLKRGLSEFVGTYTLPSGRLDQFAFIEPDDKRINFWPVVNPDKSLGAVDGHKVVV
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCEEEEEECCCCCCCCCCCCCCEEEE
RITKYPDGRFAGACDVVRIIGHKNDPGVDILSIVYKHGIPTEFPEDVIAQANAVPDEADE
EEEECCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCC
KDFIGRVDLRDETIFTIDGEDAKDLDDAVHVKKLDNGNYELGVHIADVSHYVKEGSPLDV
CCCCEEEECCCCEEEEECCCCCHHHHHHHHHEEECCCCEEEEEEEEHHHHHHHCCCCCCH
EAFERGTSVYLVDRVIPMLPHRLSNGICSLNPHVNRLTLSCVMEISPQNGKVVRHDLFPS
HHHHCCCEEEEHHHHHHHHHHHHHCCEEECCCCCHHEEEEEEEEECCCCCCEEEHHHHHH
VIKTTERMTYTNVREIIERDDEETLKKYEPFIGEFDLMAELAEVLRKRRNSRGAINFDFA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEE
EAKVVVNEEGKPADIVLRPRSVAEKLIEEFMLAANETVAEHFHKMDVPFIYRVHDNPKPD
EEEEEECCCCCCCEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCC
KLDFFFDFVANFGVHIERIKGQTVEPKTLQKILKAIDGEPEEPVISTIMLRSMQQAKYDD
HHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
VSLGHFGLATDFYTHFTSPIRRYPDLIVHRLMRTYVFNNDLSEKTIAKYEDRLGAIAEQA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
SKRERRSVDAERETQALKKAEYMEAHLGEEFDGVVAGVTNFGMFIELPNTIEGLVRLQSM
HHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEECCHHHHHHHHHHHC
DDYYHFDESQLMLLGERTKRQFRIGDAVRVKVDAVNLDERTIDFTVVGMPKREQSSRRQP
CHHHCCCCCCEEEEEHHHHHHEECCCEEEEEEEEECCCCCEEEEEEECCCCHHHHHCCCC
TTIKAKGGRPKKDEKDRRGGRGRDDKKKRGKPGRPGKPGKPGEKPKRDGEKSSQGRSALD
CEEEECCCCCCCCHHHHCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHC
LKKKDKHKRKGDAKRGAKKRR
CHHHHHHHHCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]