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The map label for this gene is speH

Identifier: 229916387

GI number: 229916387

Start: 607928

End: 608314

Strand: Reverse

Name: speH

Synonym: EAT1b_0657

Alternate gene names: 229916387

Gene position: 608314-607928 (Counterclockwise)

Preceding gene: 229916388

Following gene: 229916386

Centisome position: 20.28

GC content: 46.25

Gene sequence:

>387_bases
ATGGATACTATGGGACGTCACATTATTACAGAACTTTGGGAGTGCAATCCCGACAAATTGAATGATATCGACTACATCGA
GCGTTTGTTCGTCGATGCTGCTCTTCGTTCGGGCGCTGAAGTCCGCGAAGTTGCATTCCACAAATTTGCGCCACACGGTG
TAAGTGGAGTCGTCATCATTTCAGAATCACACTTAACGATTCACAGTTTCCCAGAACATGGCTATGCGTCAGTTGACGTG
TTTACATGTGGAGATCGAATCGATCCGGCTACAGCATCGCAGTATATTGCTGAAGGATTGGATGCAAAAGTACGTGAAGA
TGTGAAACTTGAGCGTGGAATGGGACCGATTCGTGTTCCAGAAGCGCAAGTGGCAATCAGCAAATAA

Upstream 100 bases:

>100_bases
CTTAGGACTAACTTGCCCCCGTGGTTGTGGGCGATTCAGGCACAAAGTGAGTGATCATCAACTACTTTGAGACCATTGAT
GTAAAGGGGGATCCACTAAT

Downstream 100 bases:

>100_bases
ATCAGATTGACCTTTTGAGGCTGGCCGTTTAACGGTCAGCCCTTTTAATTGTTTTGTTGTCGCCTTAATTTTGATATGCT
TAACGTATATAACTCAGGCG

Product: S-adenosylmethionine decarboxylase proenzyme

Products: NA

Alternate protein names: AdoMetDC; SAMDC

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MDTMGRHIITELWECNPDKLNDIDYIERLFVDAALRSGAEVREVAFHKFAPHGVSGVVIISESHLTIHSFPEHGYASVDV
FTCGDRIDPATASQYIAEGLDAKVREDVKLERGMGPIRVPEAQVAISK

Sequences:

>Translated_128_residues
MDTMGRHIITELWECNPDKLNDIDYIERLFVDAALRSGAEVREVAFHKFAPHGVSGVVIISESHLTIHSFPEHGYASVDV
FTCGDRIDPATASQYIAEGLDAKVREDVKLERGMGPIRVPEAQVAISK
>Mature_128_residues
MDTMGRHIITELWECNPDKLNDIDYIERLFVDAALRSGAEVREVAFHKFAPHGVSGVVIISESHLTIHSFPEHGYASVDV
FTCGDRIDPATASQYIAEGLDAKVREDVKLERGMGPIRVPEAQVAISK

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPEH_EXISA (C4L466)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002885033.1
- GeneID:   7871429
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_0657
- OMA:   ISNKFEP
- ProtClustDB:   PRK03124
- HAMAP:   MF_00464
- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716
- Gene3D:   G3DSA:3.60.90.10
- TIGRFAMs:   TIGR03330

Pfam domain/function: PF02675 AdoMet_dc; SSF56276 S-AdenosylMet_decarbase_core

EC number: =4.1.1.50

Molecular weight: Translated: 14176; Mature: 14176

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: ACT_SITE 63-63 ACT_SITE 68-68 ACT_SITE 83-83

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTMGRHIITELWECNPDKLNDIDYIERLFVDAALRSGAEVREVAFHKFAPHGVSGVVII
CCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEE
SESHLTIHSFPEHGYASVDVFTCGDRIDPATASQYIAEGLDAKVREDVKLERGMGPIRVP
ECCCEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCC
EAQVAISK
CCEEEECC
>Mature Secondary Structure
MDTMGRHIITELWECNPDKLNDIDYIERLFVDAALRSGAEVREVAFHKFAPHGVSGVVII
CCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEE
SESHLTIHSFPEHGYASVDVFTCGDRIDPATASQYIAEGLDAKVREDVKLERGMGPIRVP
ECCCEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCC
EAQVAISK
CCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA