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The map label for this gene is gapB [H]

Identifier: 229916388

GI number: 229916388

Start: 608546

End: 609577

Strand: Reverse

Name: gapB [H]

Synonym: EAT1b_0658

Alternate gene names: 229916388

Gene position: 609577-608546 (Counterclockwise)

Preceding gene: 229916390

Following gene: 229916387

Centisome position: 20.32

GC content: 50.39

Gene sequence:

>1032_bases
ATGGGGACAAAAGTGGCAATTAACGGATTTGGTCGAATCGGAAGAATGGTATTTCGAAAATTGATGCTCGAAGGACGTCA
TGAAGTAGTGGCGATTAACGCAAGTTATCCGGCGGAAACACTTGCGCATCTCATTAAACATGACTCGATTCATGGTCCAT
TCGGATTGACAGTACGTGCGCATGGGGATGCGCTCGAAGTCGATGGGAAACGGATTGAACTCATTTCGGAACGTGATCCA
TCACGCTTGCCTTGGTCAGACCTTGAAATCGACATCGTCGTCGAAGCGACCGGGAAGTTTAACTCTGATAGCGGGGCGCG
ACTTCATCTCGAGGCAGGGGCGAAAAAAGTGATTTTGACCGCACCGGGTAAAGGGGATTTACGAACGATCGTGATGGGGG
TCAATGATCGTGACTATCGCCCGGAGGAAGATCATATCATCTCAAACGCATCGTGTACGACGAACTGTCTCGGACCTGTC
GTGAAGGTCTTACATTCGACGTTCGGTATTGAAACGGGACTGATTACGACCGTTCACGCCTATACGAACGATCAGAACAA
TATTGATAACCCGCATAAAGATTTGCGTCGCGCGCGCGCGTGTGGCAGTTCCATCATCCCGACATCGACGGGAGCGGCTA
AGGCGATTGGTCTGGTGATGCCGGAACTACAAGGAAAGTTGAACGGAATGGCACTCCGTGTGCCGACTCCGAACGTATCA
CTTGTCGATTTGGTCGTCGAACTCCACCGAGATGTCACGGTCGATGAAGTCAATGAAGCGTTTGAACGGGCAGCGTTTGG
AGAAATGACAGGTATTTTAGGCGTTTCTCACGAACCGCTCGTCTCTATCGATTTTAACGGGGATGATCGCTCGTCGATTA
TCGACATGGATTCGACGATGGTGCTCGGCGGAAATCATGTCAAAGTACTCGCGTGGTATGACAACGAATGGGGCTATTCA
TGCCGTGTCGTGGACTTGTTGGACATGGTGGCCAGCTATCTTCAAATCGGTCAGCAAGAAACACACGCCTAA

Upstream 100 bases:

>100_bases
ATAAACAAAGAAAAACGAAAAAAATGTGACGATTCATAGTGAAAACGCTTACAGCTATCCGTTATAATGAAACCGTAATG
TAGAAAAAGGGGGATCTATC

Downstream 100 bases:

>100_bases
AAAATATTACGTTCAGGAAAATATTTTTGAATTTTTTTATCAAATGTCTTGTAACGACGTCCCAAACACGTTACACTCAA
TTTCGTGAACTTCAATTGGT

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase; GAPDH [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MGTKVAINGFGRIGRMVFRKLMLEGRHEVVAINASYPAETLAHLIKHDSIHGPFGLTVRAHGDALEVDGKRIELISERDP
SRLPWSDLEIDIVVEATGKFNSDSGARLHLEAGAKKVILTAPGKGDLRTIVMGVNDRDYRPEEDHIISNASCTTNCLGPV
VKVLHSTFGIETGLITTVHAYTNDQNNIDNPHKDLRRARACGSSIIPTSTGAAKAIGLVMPELQGKLNGMALRVPTPNVS
LVDLVVELHRDVTVDEVNEAFERAAFGEMTGILGVSHEPLVSIDFNGDDRSSIIDMDSTMVLGGNHVKVLAWYDNEWGYS
CRVVDLLDMVASYLQIGQQETHA

Sequences:

>Translated_343_residues
MGTKVAINGFGRIGRMVFRKLMLEGRHEVVAINASYPAETLAHLIKHDSIHGPFGLTVRAHGDALEVDGKRIELISERDP
SRLPWSDLEIDIVVEATGKFNSDSGARLHLEAGAKKVILTAPGKGDLRTIVMGVNDRDYRPEEDHIISNASCTTNCLGPV
VKVLHSTFGIETGLITTVHAYTNDQNNIDNPHKDLRRARACGSSIIPTSTGAAKAIGLVMPELQGKLNGMALRVPTPNVS
LVDLVVELHRDVTVDEVNEAFERAAFGEMTGILGVSHEPLVSIDFNGDDRSSIIDMDSTMVLGGNHVKVLAWYDNEWGYS
CRVVDLLDMVASYLQIGQQETHA
>Mature_342_residues
GTKVAINGFGRIGRMVFRKLMLEGRHEVVAINASYPAETLAHLIKHDSIHGPFGLTVRAHGDALEVDGKRIELISERDPS
RLPWSDLEIDIVVEATGKFNSDSGARLHLEAGAKKVILTAPGKGDLRTIVMGVNDRDYRPEEDHIISNASCTTNCLGPVV
KVLHSTFGIETGLITTVHAYTNDQNNIDNPHKDLRRARACGSSIIPTSTGAAKAIGLVMPELQGKLNGMALRVPTPNVSL
VDLVVELHRDVTVDEVNEAFERAAFGEMTGILGVSHEPLVSIDFNGDDRSSIIDMDSTMVLGGNHVKVLAWYDNEWGYSC
RVVDLLDMVASYLQIGQQETHA

Specific function: More active in anabolism [H]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=331, Percent_Identity=47.4320241691843, Blast_Score=297, Evalue=1e-80,
Organism=Homo sapiens, GI7657116, Length=330, Percent_Identity=47.2727272727273, Blast_Score=294, Evalue=6e-80,
Organism=Escherichia coli, GI1788079, Length=328, Percent_Identity=50.3048780487805, Blast_Score=327, Evalue=6e-91,
Organism=Escherichia coli, GI1789295, Length=329, Percent_Identity=45.2887537993921, Blast_Score=280, Evalue=8e-77,
Organism=Caenorhabditis elegans, GI17534679, Length=335, Percent_Identity=48.3582089552239, Blast_Score=308, Evalue=2e-84,
Organism=Caenorhabditis elegans, GI17534677, Length=335, Percent_Identity=48.0597014925373, Blast_Score=307, Evalue=4e-84,
Organism=Caenorhabditis elegans, GI32566163, Length=335, Percent_Identity=47.7611940298507, Blast_Score=297, Evalue=5e-81,
Organism=Caenorhabditis elegans, GI17568413, Length=335, Percent_Identity=47.7611940298507, Blast_Score=297, Evalue=6e-81,
Organism=Saccharomyces cerevisiae, GI6322409, Length=330, Percent_Identity=49.0909090909091, Blast_Score=321, Evalue=1e-88,
Organism=Saccharomyces cerevisiae, GI6322468, Length=330, Percent_Identity=49.3939393939394, Blast_Score=317, Evalue=2e-87,
Organism=Saccharomyces cerevisiae, GI6321631, Length=330, Percent_Identity=49.0909090909091, Blast_Score=315, Evalue=8e-87,
Organism=Drosophila melanogaster, GI19922412, Length=325, Percent_Identity=47.0769230769231, Blast_Score=301, Evalue=5e-82,
Organism=Drosophila melanogaster, GI17933600, Length=332, Percent_Identity=47.289156626506, Blast_Score=296, Evalue=1e-80,
Organism=Drosophila melanogaster, GI18110149, Length=332, Percent_Identity=47.289156626506, Blast_Score=296, Evalue=1e-80,
Organism=Drosophila melanogaster, GI85725000, Length=332, Percent_Identity=47.5903614457831, Blast_Score=295, Evalue=2e-80,
Organism=Drosophila melanogaster, GI22023983, Length=332, Percent_Identity=47.5903614457831, Blast_Score=295, Evalue=2e-80,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.59 [H]

Molecular weight: Translated: 37349; Mature: 37218

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTKVAINGFGRIGRMVFRKLMLEGRHEVVAINASYPAETLAHLIKHDSIHGPFGLTVRA
CCCEEEECCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCCCEEEEEEE
HGDALEVDGKRIELISERDPSRLPWSDLEIDIVVEATGKFNSDSGARLHLEAGAKKVILT
CCCEEEECCCEEEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEECCCCEEEEE
APGKGDLRTIVMGVNDRDYRPEEDHIISNASCTTNCLGPVVKVLHSTFGIETGLITTVHA
CCCCCCEEEEEECCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEE
YTNDQNNIDNPHKDLRRARACGSSIIPTSTGAAKAIGLVMPELQGKLNGMALRVPTPNVS
EECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCH
LVDLVVELHRDVTVDEVNEAFERAAFGEMTGILGVSHEPLVSIDFNGDDRSSIIDMDSTM
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEECCCEE
VLGGNHVKVLAWYDNEWGYSCRVVDLLDMVASYLQIGQQETHA
EECCCEEEEEEEECCCCCCEEHHHHHHHHHHHHHHCCCHHCCC
>Mature Secondary Structure 
GTKVAINGFGRIGRMVFRKLMLEGRHEVVAINASYPAETLAHLIKHDSIHGPFGLTVRA
CCEEEECCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCCCEEEEEEE
HGDALEVDGKRIELISERDPSRLPWSDLEIDIVVEATGKFNSDSGARLHLEAGAKKVILT
CCCEEEECCCEEEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEECCCCEEEEE
APGKGDLRTIVMGVNDRDYRPEEDHIISNASCTTNCLGPVVKVLHSTFGIETGLITTVHA
CCCCCCEEEEEECCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEE
YTNDQNNIDNPHKDLRRARACGSSIIPTSTGAAKAIGLVMPELQGKLNGMALRVPTPNVS
EECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCH
LVDLVVELHRDVTVDEVNEAFERAAFGEMTGILGVSHEPLVSIDFNGDDRSSIIDMDSTM
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEECCCEE
VLGGNHVKVLAWYDNEWGYSCRVVDLLDMVASYLQIGQQETHA
EECCCEEEEEEEECCCCCCEEHHHHHHHHHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10799476 [H]