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The map label for this gene is hrcA

Identifier: 229916348

GI number: 229916348

Start: 570215

End: 571237

Strand: Reverse

Name: hrcA

Synonym: EAT1b_0618

Alternate gene names: 229916348

Gene position: 571237-570215 (Counterclockwise)

Preceding gene: 229916350

Following gene: 229916347

Centisome position: 19.04

GC content: 48.68

Gene sequence:

>1023_bases
GTGCTGACAGATCGACAATTGCTCATTCTTCGAGCCATCATTGACGATTACATTCAGACGGCTCAGCCGGTCGGTTCTCG
AACATTGTCGAAACGAGACGATTTGACGTTTAGTTCAGCAACGATTCGGAATGATATGGCCGATTTGGAAGACATGGGGC
TGATTGAAAAACCGCATACTTCTGCAGGTCGCATCCCGTCAGAGGTCGGCTATCGATATTACGTGGACCACCTCGTCGAG
AAGCAGATCATCGACGAACGGGAGACAGGTCGACTAGAAGAACGTTTGAAACAATCTTCAAAAGAGTCTGAGATCCTGAT
TCGACAAGCTGCAGATCTCCTTTCTGATTTGACCAATTATACGACGGTCGCCCTCGGTCCGAACAGCCAAATGGAAACGT
TGGCCCGTGTGGACTTTATGCCATTAGATGAGCGGCGTGGTGTTGTTCTCATCGTCACGGATCAAGGTCATGTCGAGCAT
CGTACCGTCATGTTTGAATCGCGGGTCGCTCCTGACGTCATCGAGGAAACGATTCGACTGTTGAACGACCGCCTTGTCGG
AACGCCAATCGGACAATTGAAAATCCGGATTGGGGAGGAAGTTGCCAAATTGCAACTCGCTCAGCGACAGCAGTACGAGA
ACATGATGCAACTGATTCAATCGACGGTCGGAATCCAAACGCCGTCTTCGCTTTATCTCGGGGGCAAGAAGAAGATCTTC
AATCAACCCGAGTTTCAGACGCTCGACACGTTACGCCCATTCCTAGAATGGATTGATGAGCAAGAACGATTGACGCACTG
GCTCGAATCGTTGCCAAATCGTGAGATTTATGTGAGCATTGGGAGCGAGAACGGAATTGTCGCCCTTCAAAATTGTAGTG
TCATCACCTCGGATTATACACTAGACGGAAAAACATTCGGAACAATCGCTATGATTGGTCCAACGCGTATGAATTACCGT
CATGGTGTCCAAATGATGGGACAAATTATCGAAGCGTTGCGACGAACGAAACTAGATGAGTGA

Upstream 100 bases:

>100_bases
GACAAATAGTGAGAACATGATAATATTTGAAGTGTGATTAGCACTCGTTAAATATGAGTGCTAATAAAGCGGGGTAACCT
TTTCAGAGAGGAGTGATGTT

Downstream 100 bases:

>100_bases
CGGAAAGGAGTTTTACTATGACAGCAGATCACCAAAACGGGCATGAGCAAGATGACGTGCTTGAAGAAAAATCTGTAGAC
TCGGCACAAACAGAAGAGAA

Product: heat-inducible transcription repressor HrcA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MLTDRQLLILRAIIDDYIQTAQPVGSRTLSKRDDLTFSSATIRNDMADLEDMGLIEKPHTSAGRIPSEVGYRYYVDHLVE
KQIIDERETGRLEERLKQSSKESEILIRQAADLLSDLTNYTTVALGPNSQMETLARVDFMPLDERRGVVLIVTDQGHVEH
RTVMFESRVAPDVIEETIRLLNDRLVGTPIGQLKIRIGEEVAKLQLAQRQQYENMMQLIQSTVGIQTPSSLYLGGKKKIF
NQPEFQTLDTLRPFLEWIDEQERLTHWLESLPNREIYVSIGSENGIVALQNCSVITSDYTLDGKTFGTIAMIGPTRMNYR
HGVQMMGQIIEALRRTKLDE

Sequences:

>Translated_340_residues
MLTDRQLLILRAIIDDYIQTAQPVGSRTLSKRDDLTFSSATIRNDMADLEDMGLIEKPHTSAGRIPSEVGYRYYVDHLVE
KQIIDERETGRLEERLKQSSKESEILIRQAADLLSDLTNYTTVALGPNSQMETLARVDFMPLDERRGVVLIVTDQGHVEH
RTVMFESRVAPDVIEETIRLLNDRLVGTPIGQLKIRIGEEVAKLQLAQRQQYENMMQLIQSTVGIQTPSSLYLGGKKKIF
NQPEFQTLDTLRPFLEWIDEQERLTHWLESLPNREIYVSIGSENGIVALQNCSVITSDYTLDGKTFGTIAMIGPTRMNYR
HGVQMMGQIIEALRRTKLDE
>Mature_340_residues
MLTDRQLLILRAIIDDYIQTAQPVGSRTLSKRDDLTFSSATIRNDMADLEDMGLIEKPHTSAGRIPSEVGYRYYVDHLVE
KQIIDERETGRLEERLKQSSKESEILIRQAADLLSDLTNYTTVALGPNSQMETLARVDFMPLDERRGVVLIVTDQGHVEH
RTVMFESRVAPDVIEETIRLLNDRLVGTPIGQLKIRIGEEVAKLQLAQRQQYENMMQLIQSTVGIQTPSSLYLGGKKKIF
NQPEFQTLDTLRPFLEWIDEQERLTHWLESLPNREIYVSIGSENGIVALQNCSVITSDYTLDGKTFGTIAMIGPTRMNYR
HGVQMMGQIIEALRRTKLDE

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HRCA_EXISA (C4L427)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002884994.1
- GeneID:   7871357
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_0618
- OMA:   LEQPHTS
- ProtClustDB:   CLSK2489125
- GO:   GO:0006350
- HAMAP:   MF_00081
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF005485
- TIGRFAMs:   TIGR00331

Pfam domain/function: PF01628 HrcA

EC number: NA

Molecular weight: Translated: 38780; Mature: 38780

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTDRQLLILRAIIDDYIQTAQPVGSRTLSKRDDLTFSSATIRNDMADLEDMGLIEKPHT
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
SAGRIPSEVGYRYYVDHLVEKQIIDERETGRLEERLKQSSKESEILIRQAADLLSDLTNY
CCCCCHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHC
TTVALGPNSQMETLARVDFMPLDERRGVVLIVTDQGHVEHRTVMFESRVAPDVIEETIRL
EEEEECCCHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHEEEHHCCCHHHHHHHHHH
LNDRLVGTPIGQLKIRIGEEVAKLQLAQRQQYENMMQLIQSTVGIQTPSSLYLGGKKKIF
HHHHHCCCCHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHC
NQPEFQTLDTLRPFLEWIDEQERLTHWLESLPNREIYVSIGSENGIVALQNCSVITSDYT
CCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCEEEECCEE
LDGKTFGTIAMIGPTRMNYRHGVQMMGQIIEALRRTKLDE
ECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLTDRQLLILRAIIDDYIQTAQPVGSRTLSKRDDLTFSSATIRNDMADLEDMGLIEKPHT
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
SAGRIPSEVGYRYYVDHLVEKQIIDERETGRLEERLKQSSKESEILIRQAADLLSDLTNY
CCCCCHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHC
TTVALGPNSQMETLARVDFMPLDERRGVVLIVTDQGHVEHRTVMFESRVAPDVIEETIRL
EEEEECCCHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHEEEHHCCCHHHHHHHHHH
LNDRLVGTPIGQLKIRIGEEVAKLQLAQRQQYENMMQLIQSTVGIQTPSSLYLGGKKKIF
HHHHHCCCCHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHC
NQPEFQTLDTLRPFLEWIDEQERLTHWLESLPNREIYVSIGSENGIVALQNCSVITSDYT
CCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCEEEECCEE
LDGKTFGTIAMIGPTRMNYRHGVQMMGQIIEALRRTKLDE
ECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA