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The map label for this gene is gluP [H]

Identifier: 229916284

GI number: 229916284

Start: 500450

End: 501502

Strand: Reverse

Name: gluP [H]

Synonym: EAT1b_0553

Alternate gene names: 229916284

Gene position: 501502-500450 (Counterclockwise)

Preceding gene: 229916285

Following gene: 229916283

Centisome position: 16.72

GC content: 48.05

Gene sequence:

>1053_bases
TTGGCGACAACTTGTTTTTGGGAAGATATTTATCGAAGAGTCGAAAACGGTGGGCGAATTGAAGGCATACTCGAACCCTC
CCGTGCGGTCATCTTATTCGATACGAAAGCAGGTGATCGGTATGATTTGTTCATTCAGACTGAAAAAGCATGGGCGAATC
ACGTTGGGATGGATATACACGCGATTTTGAACGCATTTCGCTTATCTCGCATCGGGCGGAAACGATTGACCATTCATGTT
TATGGTGAGCGTCTCGTGGATGAAGAGCGTGTAGACTCGTTGACGTTCCAAATCCCTGCGAAAGTGACATTGTCCCGTTC
GATTTGCACACCGACTATGGAAGAAGACCGGTTCCGACTGCTGGCGGTCTCCCTCGACCGAAAAAAGAAGGCGGAGCTGA
AGAAACGATTTTCTTTCGGGAAACCACAAGTGGTGTATGGGCTACTGTTCGTCACCTTTTTAGTCATGTGGTTAGCTGAA
TCGGTCGGTTCGACGCTTGATCCGAACACGCTGGTCGCATTCGGGGCCAAAGTGAACCCGTTGATTGAACAAGGGGAATG
GTGGCGTTTGATTACACCGATGTTCCTGCATATCGGTTGGTTCCATTTTGCGATTAATATGTTTGCACTCTGGTCGCTCG
GTCCGCTCGTCGAACGGATGTACGGCTCCATACGATTTTTAATCATCTATCTGCTCAGTGGAATATTAGCGACATCCGCA
TCGTTTGCATTCAGCGAATCGATATCAGCAGGCGCTTCAGGAGCGTTATTTGGATTGGTCGGTGCGCTCTTATACTTTGG
GTTGCGTGATCGTTCTCTCTTCATGAAGACGCTCGGACCTCCGCTCTTTATTATGTTAGGATTAAACGTAGGACTTGCGT
TTGTATTAGGTGCAGGTCTTGACCATTTCGCACATGCGGGAGGTCTGATTGGAGGTTTTGTCGTTTCTGGAGTCGTCGGG
CTACCGGATGAGAAGAACCGTATACAACGAATCTTATTTTCCGTACTCACCATCTCGATGTTTGGACTATTCGTCGGGTA
CGGATTTTGGTAA

Upstream 100 bases:

>100_bases
GCCATATGGTTACGGGTTTTTATACATATAGAACGAATCATCGTTTGGTCGTGGGTCGTGTCGTGATTTACAATAGAATT
GAGAGAGAGGAGGGGTTTCT

Downstream 100 bases:

>100_bases
GGGGAGAATTCAATGATTGAAACATTAAAAACACTCGTTAACATCCCGAGTCCTTCCGGGATGACGGAAGAGGCCATCCG
CTTCGCGGAGCAAGAATTGA

Product: Rhomboid family protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MATTCFWEDIYRRVENGGRIEGILEPSRAVILFDTKAGDRYDLFIQTEKAWANHVGMDIHAILNAFRLSRIGRKRLTIHV
YGERLVDEERVDSLTFQIPAKVTLSRSICTPTMEEDRFRLLAVSLDRKKKAELKKRFSFGKPQVVYGLLFVTFLVMWLAE
SVGSTLDPNTLVAFGAKVNPLIEQGEWWRLITPMFLHIGWFHFAINMFALWSLGPLVERMYGSIRFLIIYLLSGILATSA
SFAFSESISAGASGALFGLVGALLYFGLRDRSLFMKTLGPPLFIMLGLNVGLAFVLGAGLDHFAHAGGLIGGFVVSGVVG
LPDEKNRIQRILFSVLTISMFGLFVGYGFW

Sequences:

>Translated_350_residues
MATTCFWEDIYRRVENGGRIEGILEPSRAVILFDTKAGDRYDLFIQTEKAWANHVGMDIHAILNAFRLSRIGRKRLTIHV
YGERLVDEERVDSLTFQIPAKVTLSRSICTPTMEEDRFRLLAVSLDRKKKAELKKRFSFGKPQVVYGLLFVTFLVMWLAE
SVGSTLDPNTLVAFGAKVNPLIEQGEWWRLITPMFLHIGWFHFAINMFALWSLGPLVERMYGSIRFLIIYLLSGILATSA
SFAFSESISAGASGALFGLVGALLYFGLRDRSLFMKTLGPPLFIMLGLNVGLAFVLGAGLDHFAHAGGLIGGFVVSGVVG
LPDEKNRIQRILFSVLTISMFGLFVGYGFW
>Mature_349_residues
ATTCFWEDIYRRVENGGRIEGILEPSRAVILFDTKAGDRYDLFIQTEKAWANHVGMDIHAILNAFRLSRIGRKRLTIHVY
GERLVDEERVDSLTFQIPAKVTLSRSICTPTMEEDRFRLLAVSLDRKKKAELKKRFSFGKPQVVYGLLFVTFLVMWLAES
VGSTLDPNTLVAFGAKVNPLIEQGEWWRLITPMFLHIGWFHFAINMFALWSLGPLVERMYGSIRFLIIYLLSGILATSAS
FAFSESISAGASGALFGLVGALLYFGLRDRSLFMKTLGPPLFIMLGLNVGLAFVLGAGLDHFAHAGGLIGGFVVSGVVGL
PDEKNRIQRILFSVLTISMFGLFVGYGFW

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Important for normal cell division and sporulation. May act as a glucose exporter [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002610
- InterPro:   IPR022764
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF01694 Rhomboid; PF00515 TPR_1 [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 39136; Mature: 39004

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTCFWEDIYRRVENGGRIEGILEPSRAVILFDTKAGDRYDLFIQTEKAWANHVGMDIH
CCCHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCEEEEEEEECHHHHHHCCCHHH
AILNAFRLSRIGRKRLTIHVYGERLVDEERVDSLTFQIPAKVTLSRSICTPTMEEDRFRL
HHHHHHHHHHCCCCEEEEEEECCHHCCHHHHHHEEEEECCEEEECHHHCCCCCCCCCEEE
LAVSLDRKKKAELKKRFSFGKPQVVYGLLFVTFLVMWLAESVGSTLDPNTLVAFGAKVNP
EEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCH
LIEQGEWWRLITPMFLHIGWFHFAINMFALWSLGPLVERMYGSIRFLIIYLLSGILATSA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFAFSESISAGASGALFGLVGALLYFGLRDRSLFMKTLGPPLFIMLGLNVGLAFVLGAGL
HHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHCCH
DHFAHAGGLIGGFVVSGVVGLPDEKNRIQRILFSVLTISMFGLFVGYGFW
HHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ATTCFWEDIYRRVENGGRIEGILEPSRAVILFDTKAGDRYDLFIQTEKAWANHVGMDIH
CCHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCEEEEEEEECHHHHHHCCCHHH
AILNAFRLSRIGRKRLTIHVYGERLVDEERVDSLTFQIPAKVTLSRSICTPTMEEDRFRL
HHHHHHHHHHCCCCEEEEEEECCHHCCHHHHHHEEEEECCEEEECHHHCCCCCCCCCEEE
LAVSLDRKKKAELKKRFSFGKPQVVYGLLFVTFLVMWLAESVGSTLDPNTLVAFGAKVNP
EEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCH
LIEQGEWWRLITPMFLHIGWFHFAINMFALWSLGPLVERMYGSIRFLIIYLLSGILATSA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFAFSESISAGASGALFGLVGALLYFGLRDRSLFMKTLGPPLFIMLGLNVGLAFVLGAGL
HHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHCCH
DHFAHAGGLIGGFVVSGVVGLPDEKNRIQRILFSVLTISMFGLFVGYGFW
HHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]