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The map label for this gene is resD [H]

Identifier: 229916170

GI number: 229916170

Start: 402488

End: 403204

Strand: Reverse

Name: resD [H]

Synonym: EAT1b_0439

Alternate gene names: 229916170

Gene position: 403204-402488 (Counterclockwise)

Preceding gene: 229916171

Following gene: 229916169

Centisome position: 13.44

GC content: 49.09

Gene sequence:

>717_bases
ATGGCTGAGAAAACGAAGATTTTAGTAGTCGACGACGAGGAGAGAATTCGCCGACTTTTGAAAATGTACTTAGAACGTGA
ACAGTATGTGATTGAAGAAGCGGTCAATGGCGAAGAGGCGCTCGCGCTTGCCCTTGAAAACGAATACGACGTGATCTTGC
TTGATTTGATGATGCCAAAGATGGATGGGGTTGAAGTATGTACAGAACTCCGGAAGACGAAAGCGACTCCGGTCATCATG
CTCACAGCGAAAGGTGAGGAAATCGATCGTGTTCAAGGGTTTGAAGTCGGGGCGGATGATTACATCGTCAAGCCGTTCAG
TCCGCGTGAAGTCGTGCTCCGCGTCAAGGCACTCCTTCGCCGCTCTGGTTCGACAAAGTTCATGCACACGAGTGAGAAGT
CGAAGGATTTGATCGTCTTCCCACATCTCACAATCGATAATGATGCACACCGCGTCACGGTGGACGGCGAGGAAATCGCC
CTCACACCAAAAGAATATGAGTTATTGTTCTTCCTCGCCAAGCAGGTGGATAAAGTCTTTTCACGAGAGCAGTTGTTAAA
AGAAGTATGGAACTACGAATTTTTCGGAGACCTTCGGACCGTCGATACGCATGTGAAACGTCTTCGTGAGAAATTGAATC
GTGTCTCACCGGACGCGGCGCATATGATCACGACCGTATGGGGTGTCGGGTACAAGTTCGAAGCTGCCAGTGAATGA

Upstream 100 bases:

>100_bases
AGCGAAATAATAGAGTGGTATAGTTATGGCAGAGAGTGGAATGTTCACAATTGTGCAACATTCGCTACAACTCGTAATGG
GTCTTAGGAGGGTTTCAGGT

Downstream 100 bases:

>100_bases
TGATTCGTCGAAACAGCATCGTCACGAAACTGTGGCTGACGATTCTCGTTTTGGTCAGTGTCATCTTATTCATCGTCTCG
GTGTTGATGCTTGAATTTTT

Product: two component transcriptional regulator, winged helix family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MAEKTKILVVDDEERIRRLLKMYLEREQYVIEEAVNGEEALALALENEYDVILLDLMMPKMDGVEVCTELRKTKATPVIM
LTAKGEEIDRVQGFEVGADDYIVKPFSPREVVLRVKALLRRSGSTKFMHTSEKSKDLIVFPHLTIDNDAHRVTVDGEEIA
LTPKEYELLFFLAKQVDKVFSREQLLKEVWNYEFFGDLRTVDTHVKRLREKLNRVSPDAAHMITTVWGVGYKFEAASE

Sequences:

>Translated_238_residues
MAEKTKILVVDDEERIRRLLKMYLEREQYVIEEAVNGEEALALALENEYDVILLDLMMPKMDGVEVCTELRKTKATPVIM
LTAKGEEIDRVQGFEVGADDYIVKPFSPREVVLRVKALLRRSGSTKFMHTSEKSKDLIVFPHLTIDNDAHRVTVDGEEIA
LTPKEYELLFFLAKQVDKVFSREQLLKEVWNYEFFGDLRTVDTHVKRLREKLNRVSPDAAHMITTVWGVGYKFEAASE
>Mature_237_residues
AEKTKILVVDDEERIRRLLKMYLEREQYVIEEAVNGEEALALALENEYDVILLDLMMPKMDGVEVCTELRKTKATPVIML
TAKGEEIDRVQGFEVGADDYIVKPFSPREVVLRVKALLRRSGSTKFMHTSEKSKDLIVFPHLTIDNDAHRVTVDGEEIAL
TPKEYELLFFLAKQVDKVFSREQLLKEVWNYEFFGDLRTVDTHVKRLREKLNRVSPDAAHMITTVWGVGYKFEAASE

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=231, Percent_Identity=41.991341991342, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1786599, Length=231, Percent_Identity=40.6926406926407, Blast_Score=167, Evalue=5e-43,
Organism=Escherichia coli, GI87082012, Length=230, Percent_Identity=38.2608695652174, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1789809, Length=236, Percent_Identity=36.864406779661, Blast_Score=158, Evalue=2e-40,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=38.6266094420601, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=38.0952380952381, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1790860, Length=234, Percent_Identity=38.4615384615385, Blast_Score=143, Evalue=9e-36,
Organism=Escherichia coli, GI1786911, Length=230, Percent_Identity=35.6521739130435, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=32.4561403508772, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1790552, Length=234, Percent_Identity=33.7606837606838, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=33.1896551724138, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1789402, Length=229, Percent_Identity=30.5676855895196, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787375, Length=230, Percent_Identity=30.4347826086957, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=30.9012875536481, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1788550, Length=165, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788191, Length=112, Percent_Identity=35.7142857142857, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1788222, Length=116, Percent_Identity=32.7586206896552, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27482; Mature: 27351

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKTKILVVDDEERIRRLLKMYLEREQYVIEEAVNGEEALALALENEYDVILLDLMMPK
CCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCC
MDGVEVCTELRKTKATPVIMLTAKGEEIDRVQGFEVGADDYIVKPFSPREVVLRVKALLR
CCHHHHHHHHHHCCCCCEEEEEECCCHHHHCCCCEECCCCEEECCCCHHHHHHHHHHHHH
RSGSTKFMHTSEKSKDLIVFPHLTIDNDAHRVTVDGEEIALTPKEYELLFFLAKQVDKVF
CCCCCCEEECCCCCCCEEEEEEEEECCCCCEEEECCCEEEECCCHHHHHHHHHHHHHHHH
SREQLLKEVWNYEFFGDLRTVDTHVKRLREKLNRVSPDAAHMITTVWGVGYKFEAASE
HHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEECCCCC
>Mature Secondary Structure 
AEKTKILVVDDEERIRRLLKMYLEREQYVIEEAVNGEEALALALENEYDVILLDLMMPK
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCC
MDGVEVCTELRKTKATPVIMLTAKGEEIDRVQGFEVGADDYIVKPFSPREVVLRVKALLR
CCHHHHHHHHHHCCCCCEEEEEECCCHHHHCCCCEECCCCEEECCCCHHHHHHHHHHHHH
RSGSTKFMHTSEKSKDLIVFPHLTIDNDAHRVTVDGEEIALTPKEYELLFFLAKQVDKVF
CCCCCCEEECCCCCCCEEEEEEEEECCCCCEEEECCCEEEECCCHHHHHHHHHHHHHHHH
SREQLLKEVWNYEFFGDLRTVDTHVKRLREKLNRVSPDAAHMITTVWGVGYKFEAASE
HHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]