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The map label for this gene is tkt [H]

Identifier: 229916135

GI number: 229916135

Start: 368065

End: 370047

Strand: Reverse

Name: tkt [H]

Synonym: EAT1b_0404

Alternate gene names: 229916135

Gene position: 370047-368065 (Counterclockwise)

Preceding gene: 229916136

Following gene: 229916134

Centisome position: 12.34

GC content: 50.38

Gene sequence:

>1983_bases
GTGGAAACAACTACTAAAGAATTATTAGCGATTAACTCGATTCGGACGCTCTCAATTGATGCGGTCCAAAAAGCGAACTC
TGGTCACCCAGGGATGCCGATGGGCGCTGCCCCAATGGCGTTTACACTTTGGACAGATAAAATGCGTCACAACCCGAAAA
ACCCGAACTGGTTCAACCGTGACCGTTTCGTGCTTTCAGCGGGTCATGGATCGATGCTCTTGTATTCGCTCCTTCACTTG
TCTGGCTATGATTTGTCGATGGACGATTTGAAATCATTCCGTCAAATGGACTCGAAAACACCTGGTCACCCTGAGTACCG
CCACACGGCTGGGGTAGATGCGACAACGGGCCCACTTGGACAAGGGATTGCGATGGCTGTCGGGATGGCCATGGCAGAGA
AACACTTAGAAGCGACTTACAACCGCGACGAGTTCAACGTCGTTGACCACTACACGTTCGGCATTTGCGGTGACGGAGAC
TTGATGGAAGGTGTATCTGCTGAGGCGGCTTCCCTTGCAGGTCACTTGAAACTTGGTAAACTCGTCGTTCTTTACGATTC
AAACGACATCTCTCTCGATGGCGACCTTCATAAGTCATTCTCTGAAAGCGTAGAAGACCGATTCAACGCTTATGGATGGC
AAGTTATTCGTGTCGAAGACGGAACGGACATCGATTCAATCGCAAAAGCGATTGATGCTGCAAAAGCAGAGACGTCGAAG
CCGACATTGATCGAAGTTAAAACGGTCATCGGATTCGGTTCACCGAACAAGTCGGGTAAATCGGCATCACACGGTGCGCC
ACTTGGAGACGCTGAAATCGAATTGACGAAACAGTTCTACAAATGGGAAGGCGAGTCATTCTACGTTCCAAACGAAGTAT
ATGACTTATTCAACGAGAAAGTTGTCGAGCCTGGTGCGAAATATGAGTCAGACTGGAACGAACTCGTTGAAGCGTATAAA
GCGGCACACCCTGAGCTCGGAGCACAGTTCGAGCGTGCGATGAACAATGAGCTTCCTGAAGGTTGGGATAGCGAGTTGCC
GACATTCGAAATCGGTTCGAAAAAAGCAACACGTCAAACGAGCGGTGAAGTGTTAAACGCAATCGCAAAAGCAGTACCGA
CACTCTTCGGTGGGTCAGCTGACCTTGCCGGATCGAACAACTCGATGATCAAAGGTGCGGCAGACTTCGATGAAGATCCA
GCTGGCCGTAACATCTGGTTCGGTGTTCGTGAGTTCGCGATGGCTGCAGCTGTGAACGGTATGGCCCTTCACGGTGGTGT
CCTTCCTTACGGTGCGACGTTCTTCGTCTTCTCGGATTACCTCCGTCCTGCAGTCCGTCTCGCAGCACTTATGGGACTTC
CATCGACGTTCATCTTGACGCACGACTCAATCGCAGTCGGTGAAGATGGCCCAACGCACGAGCCGGTCGAACATTTGATG
AGCTTCCGCGCGATGCCGAACCTCTCTGTTCTTCGTCCTGCTGACGGCAAAGAAACGATTGCAGCTTGGAAACAAGCAGT
GACATCGAAAACGACTCCTTCACTTCTCGTCTTGACTCGTCAAGCGTTACCAGAACTCGAAGGTACATCTATTGAAACGG
CAGCAAAAGGAGCTTACGTCGTTGCAGGTGAATCGAAAGATGCAGACGTTCTCTTGCTCGGTACAGGTTCTGAAGTACAC
GTTCTCGTTGAAGCGCGTGAACAGCTCGCGTCAGAAGGCGTGAAAGCGGCAGTCGTCTCGATGCCATCATGGGAACTCTT
CGAAGCGCAATCTGCAGAGTACAAAGAATCTGTCCTTCCATCTTCAGTCACGAAACGTGTATCACTTGAAGCGGGTGCGA
CACTAGGATGGTACAAATATGTAGGATTCGGTGGTAAAGTGCTCGGAATCGACAAGTTCGGAGCATCTGCACCTGGTGAC
CTCCTCATGAAAGAATACGGCATGTCAGTCGACAACGTCGTCAATGCAGTAAAATCACTTTAA

Upstream 100 bases:

>100_bases
CACCAAATGTGTTATACTAATTAATTAGTTGTGACACACGATTGAGTGTGATAAAATATGACGGGTAGAAAACCTTCTTA
ACACAGAGAGGATGAAATTA

Downstream 100 bases:

>100_bases
TCTCTAGTTAGATTGATGTGACGGCCAATCGTTTGGCCGTCACTTTTTTTCTGGACGACTAGCGAAGTTGTTCAATTTAG
TGTATAGTAAAAAACGATGT

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 660; Mature: 660

Protein sequence:

>660_residues
METTTKELLAINSIRTLSIDAVQKANSGHPGMPMGAAPMAFTLWTDKMRHNPKNPNWFNRDRFVLSAGHGSMLLYSLLHL
SGYDLSMDDLKSFRQMDSKTPGHPEYRHTAGVDATTGPLGQGIAMAVGMAMAEKHLEATYNRDEFNVVDHYTFGICGDGD
LMEGVSAEAASLAGHLKLGKLVVLYDSNDISLDGDLHKSFSESVEDRFNAYGWQVIRVEDGTDIDSIAKAIDAAKAETSK
PTLIEVKTVIGFGSPNKSGKSASHGAPLGDAEIELTKQFYKWEGESFYVPNEVYDLFNEKVVEPGAKYESDWNELVEAYK
AAHPELGAQFERAMNNELPEGWDSELPTFEIGSKKATRQTSGEVLNAIAKAVPTLFGGSADLAGSNNSMIKGAADFDEDP
AGRNIWFGVREFAMAAAVNGMALHGGVLPYGATFFVFSDYLRPAVRLAALMGLPSTFILTHDSIAVGEDGPTHEPVEHLM
SFRAMPNLSVLRPADGKETIAAWKQAVTSKTTPSLLVLTRQALPELEGTSIETAAKGAYVVAGESKDADVLLLGTGSEVH
VLVEAREQLASEGVKAAVVSMPSWELFEAQSAEYKESVLPSSVTKRVSLEAGATLGWYKYVGFGGKVLGIDKFGASAPGD
LLMKEYGMSVDNVVNAVKSL

Sequences:

>Translated_660_residues
METTTKELLAINSIRTLSIDAVQKANSGHPGMPMGAAPMAFTLWTDKMRHNPKNPNWFNRDRFVLSAGHGSMLLYSLLHL
SGYDLSMDDLKSFRQMDSKTPGHPEYRHTAGVDATTGPLGQGIAMAVGMAMAEKHLEATYNRDEFNVVDHYTFGICGDGD
LMEGVSAEAASLAGHLKLGKLVVLYDSNDISLDGDLHKSFSESVEDRFNAYGWQVIRVEDGTDIDSIAKAIDAAKAETSK
PTLIEVKTVIGFGSPNKSGKSASHGAPLGDAEIELTKQFYKWEGESFYVPNEVYDLFNEKVVEPGAKYESDWNELVEAYK
AAHPELGAQFERAMNNELPEGWDSELPTFEIGSKKATRQTSGEVLNAIAKAVPTLFGGSADLAGSNNSMIKGAADFDEDP
AGRNIWFGVREFAMAAAVNGMALHGGVLPYGATFFVFSDYLRPAVRLAALMGLPSTFILTHDSIAVGEDGPTHEPVEHLM
SFRAMPNLSVLRPADGKETIAAWKQAVTSKTTPSLLVLTRQALPELEGTSIETAAKGAYVVAGESKDADVLLLGTGSEVH
VLVEAREQLASEGVKAAVVSMPSWELFEAQSAEYKESVLPSSVTKRVSLEAGATLGWYKYVGFGGKVLGIDKFGASAPGD
LLMKEYGMSVDNVVNAVKSL
>Mature_660_residues
METTTKELLAINSIRTLSIDAVQKANSGHPGMPMGAAPMAFTLWTDKMRHNPKNPNWFNRDRFVLSAGHGSMLLYSLLHL
SGYDLSMDDLKSFRQMDSKTPGHPEYRHTAGVDATTGPLGQGIAMAVGMAMAEKHLEATYNRDEFNVVDHYTFGICGDGD
LMEGVSAEAASLAGHLKLGKLVVLYDSNDISLDGDLHKSFSESVEDRFNAYGWQVIRVEDGTDIDSIAKAIDAAKAETSK
PTLIEVKTVIGFGSPNKSGKSASHGAPLGDAEIELTKQFYKWEGESFYVPNEVYDLFNEKVVEPGAKYESDWNELVEAYK
AAHPELGAQFERAMNNELPEGWDSELPTFEIGSKKATRQTSGEVLNAIAKAVPTLFGGSADLAGSNNSMIKGAADFDEDP
AGRNIWFGVREFAMAAAVNGMALHGGVLPYGATFFVFSDYLRPAVRLAALMGLPSTFILTHDSIAVGEDGPTHEPVEHLM
SFRAMPNLSVLRPADGKETIAAWKQAVTSKTTPSLLVLTRQALPELEGTSIETAAKGAYVVAGESKDADVLLLGTGSEVH
VLVEAREQLASEGVKAAVVSMPSWELFEAQSAEYKESVLPSSVTKRVSLEAGATLGWYKYVGFGGKVLGIDKFGASAPGD
LLMKEYGMSVDNVVNAVKSL

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=571, Percent_Identity=28.5464098073555, Blast_Score=184, Evalue=3e-46,
Organism=Homo sapiens, GI4507521, Length=571, Percent_Identity=28.5464098073555, Blast_Score=184, Evalue=3e-46,
Organism=Homo sapiens, GI133778974, Length=578, Percent_Identity=27.1626297577855, Blast_Score=159, Evalue=1e-38,
Organism=Homo sapiens, GI225637459, Length=677, Percent_Identity=22.5997045790251, Blast_Score=111, Evalue=3e-24,
Organism=Homo sapiens, GI225637463, Length=502, Percent_Identity=23.1075697211155, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI225637461, Length=602, Percent_Identity=23.0897009966777, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI48994911, Length=665, Percent_Identity=52.1804511278196, Blast_Score=688, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=650, Percent_Identity=49.8461538461538, Blast_Score=654, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=668, Percent_Identity=27.0958083832335, Blast_Score=183, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6325331, Length=662, Percent_Identity=49.3957703927492, Blast_Score=616, Evalue=1e-177,
Organism=Saccharomyces cerevisiae, GI6319593, Length=658, Percent_Identity=48.0243161094225, Blast_Score=600, Evalue=1e-172,
Organism=Drosophila melanogaster, GI45551847, Length=661, Percent_Identity=27.3827534039334, Blast_Score=186, Evalue=7e-47,
Organism=Drosophila melanogaster, GI45550715, Length=661, Percent_Identity=27.3827534039334, Blast_Score=186, Evalue=7e-47,
Organism=Drosophila melanogaster, GI24645119, Length=633, Percent_Identity=27.0142180094787, Blast_Score=170, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24666278, Length=574, Percent_Identity=27.8745644599303, Blast_Score=168, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 71070; Mature: 71070

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00801 TRANSKETOLASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METTTKELLAINSIRTLSIDAVQKANSGHPGMPMGAAPMAFTLWTDKMRHNPKNPNWFNR
CCCCHHHHHHHCCCEEEEHHHHHHCCCCCCCCCCCCCCEEEEEEHHHHHCCCCCCCCCCC
DRFVLSAGHGSMLLYSLLHLSGYDLSMDDLKSFRQMDSKTPGHPEYRHTAGVDATTGPLG
CEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
QGIAMAVGMAMAEKHLEATYNRDEFNVVDHYTFGICGDGDLMEGVSAEAASLAGHLKLGK
CHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCHHHHCCCHHHHHHHCCEEECC
LVVLYDSNDISLDGDLHKSFSESVEDRFNAYGWQVIRVEDGTDIDSIAKAIDAAKAETSK
EEEEECCCCCEECCHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHCCCCC
PTLIEVKTVIGFGSPNKSGKSASHGAPLGDAEIELTKQFYKWEGESFYVPNEVYDLFNEK
CEEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEECCHHHHHHHHHH
VVEPGAKYESDWNELVEAYKAAHPELGAQFERAMNNELPEGWDSELPTFEIGSKKATRQT
HCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCEEECCCCHHHHHH
SGEVLNAIAKAVPTLFGGSADLAGSNNSMIKGAADFDEDPAGRNIWFGVREFAMAAAVNG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCEEHHHHHHHHHHHHCC
MALHGGVLPYGATFFVFSDYLRPAVRLAALMGLPSTFILTHDSIAVGEDGPTHEPVEHLM
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEECCCCCCHHHHHHHH
SFRAMPNLSVLRPADGKETIAAWKQAVTSKTTPSLLVLTRQALPELEGTSIETAAKGAYV
HHHCCCCCCEECCCCCHHHHHHHHHHHHCCCCCHHEEEEHHHCCCCCCCCCCHHCCCEEE
VAGESKDADVLLLGTGSEVHVLVEAREQLASEGVKAAVVSMPSWELFEAQSAEYKESVLP
EECCCCCCCEEEEECCCCEEEEHHHHHHHHHCCCEEEEEECCCHHHHHCCCHHHHHHHCC
SSVTKRVSLEAGATLGWYKYVGFGGKVLGIDKFGASAPGDLLMKEYGMSVDNVVNAVKSL
HHHHHHEECCCCCCCCHHHHHCCCCEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHCC
>Mature Secondary Structure
METTTKELLAINSIRTLSIDAVQKANSGHPGMPMGAAPMAFTLWTDKMRHNPKNPNWFNR
CCCCHHHHHHHCCCEEEEHHHHHHCCCCCCCCCCCCCCEEEEEEHHHHHCCCCCCCCCCC
DRFVLSAGHGSMLLYSLLHLSGYDLSMDDLKSFRQMDSKTPGHPEYRHTAGVDATTGPLG
CEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
QGIAMAVGMAMAEKHLEATYNRDEFNVVDHYTFGICGDGDLMEGVSAEAASLAGHLKLGK
CHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCHHHHCCCHHHHHHHCCEEECC
LVVLYDSNDISLDGDLHKSFSESVEDRFNAYGWQVIRVEDGTDIDSIAKAIDAAKAETSK
EEEEECCCCCEECCHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHCCCCC
PTLIEVKTVIGFGSPNKSGKSASHGAPLGDAEIELTKQFYKWEGESFYVPNEVYDLFNEK
CEEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEECCHHHHHHHHHH
VVEPGAKYESDWNELVEAYKAAHPELGAQFERAMNNELPEGWDSELPTFEIGSKKATRQT
HCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCEEECCCCHHHHHH
SGEVLNAIAKAVPTLFGGSADLAGSNNSMIKGAADFDEDPAGRNIWFGVREFAMAAAVNG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCEEHHHHHHHHHHHHCC
MALHGGVLPYGATFFVFSDYLRPAVRLAALMGLPSTFILTHDSIAVGEDGPTHEPVEHLM
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEECCCCCCHHHHHHHH
SFRAMPNLSVLRPADGKETIAAWKQAVTSKTTPSLLVLTRQALPELEGTSIETAAKGAYV
HHHCCCCCCEECCCCCHHHHHHHHHHHHCCCCCHHEEEEHHHCCCCCCCCCCHHCCCEEE
VAGESKDADVLLLGTGSEVHVLVEAREQLASEGVKAAVVSMPSWELFEAQSAEYKESVLP
EECCCCCCCEEEEECCCCEEEEHHHHHHHHHCCCEEEEEECCCHHHHHCCCHHHHHHHCC
SSVTKRVSLEAGATLGWYKYVGFGGKVLGIDKFGASAPGDLLMKEYGMSVDNVVNAVKSL
HHHHHHEECCCCCCCCHHHHHCCCCEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]